Deconjugation of bile acids by intestinal lactobacilli.

Abstract:

:Lactobacillus species normally found in the intestinal tract of humans varied in the ability to deconjugate bile acids, whereas laboratory strains of Lactobacillus acidophilus deconjugated both glycocholate and taurocholate. All isolates of L. acidophilus from human feces deconjugated taurocholate, whereas only one of six deconjugated glycocholate. None of 13 isolates identified as L. casei deconjugated taurocholate, whereas 9 deconjugated glycocholate. The deconjugating system of L. acidophilus appeared to be constitutive, required low oxidation-reduction potential, and was most active at pH 6. No degradation beyond deconjugation was detected.

journal_name

Appl Environ Microbiol

authors

Gilliland SE,Speck ML

doi

10.1128/AEM.33.1.15-18.1977

keywords:

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

15-8

issue

1

eissn

0099-2240

issn

1098-5336

journal_volume

33

pub_type

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