Abstract:
:Blood serum concentrations of thyrotropic hormone (TSH), triiodothyronine (T3), thyroxine (T4) and cortisol have been measured in 50 patients with duodenal ulcer. The determinations were repeated after a specific time of treatment with ranitidine: in 45 patients after 3 weeks and in 37 after additional 30 days of treatment. During the first period of treatment ranitidine was administered at a dose of 300 mg divided into two daily doses and during the second period of treatment at a single daily dose of 150 mg. A small but statistically significant changes, an increase in T3 and a decrease in TSH concentration, were observed before the treatment. No changes concerning these two parameters were found as an effect of the treatment. A decrease in the concentration of T4 was found, on the other hand, after three weeks of ranitidine administration. This decrease persisted after further 30 days of chronic treatment with ranitidine. No significant changes concerning blood serum cortisol concentration were found in any of the studied groups.
journal_name
Endokrynol Poljournal_title
Endokrynologia Polskaauthors
Przybyłowski J,Kowalski D,Widłak H,Kowalska K,Garmulewicz Mkeywords:
subject
Has Abstractpub_date
1991-01-01 00:00:00pages
415-20issue
3eissn
0423-104Xissn
2299-8306journal_volume
42pub_type
杂志文章abstract::Thyroid disorders are more frequently observed in diabetic patients. These conditions have been shown to be mainly of autoimmune origin and all of them may lead to hormonal imbalance. Especially strong links exist between autoimmune thyroid diseases (AITD) and type 1 diabetes. Importantly, both hypothyroidism and hype...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,实务指引
doi:
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignancies and constitutes approximately 1.6-5% of the malignant neoplasms of the thyroid gland. ATC usually manifests itself with the local symptoms due to a rapidly enlarging thyroid mass, and as other thyroid cancers, has only seld...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.a2018.0010
更新日期:2018-01-01 00:00:00
abstract::A group of 153 patients with scintigraphically detected autonomic "hot" nodules of the thyroid has been subjected to clinical and histopathological analysis. Substantial part of these patients (30.1%) had hyperthyroidism, partly (in 19.9% of cases) in the form of the thyrocardiac syndrome. A most frequent histopatholo...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::We present the diagnostic and therapeutic difficulties encountered in a patient with a clinically advanced pancreatic neuroendocrine tumour. The report concerns a 60-year-old female patient with the diagnosis of non-functioning pancreatic neuroendocrine tumour (NET G1) with liver, peripancreatic lymph node and mediast...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::Most medical agents currently applied in osteoporosis therapy act by inhibiting bone resorption and reducing bone remodelling, i.e. they inhibit the process of bone mass loss by suppressing bone resorption processes. These drugs provide an ideal therapeutic option to prevent osteoporosis progression. They however have...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
abstract::Primary aldosteronism is the commonest form of hormone-related hypertension, with an estimated prevalence of 6-13% in the generalpopulation of hypertensive patients. Among patients with resistant hypertension, the proportion of PA is even higher. Through intensiveresearch in the field of basic science and the creation...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/ep.2013.0011
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Follicular Lesion of Undetermined Significance (FLUS) belongs to the most controversial category of the Bethesda System. The aim of the study was to specify the risk of malignancy in patients with FLUS diagnosis in the material from the Institute of Oncology in Gliwice. This is the first Polish study speci...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.2016.0002
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:In the current study, we evaluated the accuracy of sentinel node mapping in thyroid cancer patients using both radiotracer and blue dye. MATERIAL AND METHODS:30 patients with a diagnosis of papillary thyroid carcinoma (PTC) were included in the study; 2-3 hours before surgery, 0.5 mCi 99m-Tc-Antimony Sulf...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.2014.0038
更新日期:2014-01-01 00:00:00
abstract::The aim of immunohistochemistry and immunocytochemistry is to reveal specific antigens in cells and tissue samples. Those techniques are based on an antigen-antibody reaction and visualization of its product in microscopic examination. The precursor of this new diagnostic procedure was an immunofluorescent reaction in...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2005-05-01 00:00:00
abstract::Renalase is a recently identified flavoprotein oxidase, secreted mainly by the kidneys, which takes part in the degradation of catecholamines. The catecholamine inactivating effect results in the modulation of the sympathetic system tension and, consequently, in a decrease of blood pressure, myocardial contractility, ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2020.0044
更新日期:2020-01-01 00:00:00
abstract::The study was aimed at the assessment of frequency of occurrence of thyroid antimicrosomal and antithyreoglobuln autoantibodies in children with insulin-dependent diabetes and healthy control children. The occurrence of thyroid autoantibodies was analyzed with respect to the age and sex of children and the duration of...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION:Patients with hypogonadism are at increased risk of cardiac and metabolic diseases and osteoporosis. Vitamin D and Fibroblast growth factor-23 (FGF-23) play role in the regulation of bone mineral metabolism and endothelial functions. Low vitamin D levels are reported in hypogonadism, while there is no data...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2017.0009
更新日期:2017-01-01 00:00:00
abstract::Osteoporosis is a chronic disease of the osseous system characterised by decreased strength of bone tissue, which in turn leads to increased fracture risk. It has been demonstrated that osteoporosis affects more than 30% of women after the menopause (WHO, 1994). However, the disease is also observed in men. The primar...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
abstract::We describe a 37 year-old woman case of latent autoimmune diabetes in adults (LADA). She was presented with unfounded weight loss. The diagnosis of diabetes mellitus was established on twice plasma glucose measurements above 200 mg/dl. In other routine biochemical examinations we did not observe dehydratation, electro...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2006-05-01 00:00:00
abstract::The paper concerns osteonecrosis of the jaw (ONJ). It is a rare but serious clinical condition. It can develop in patients treated in oncologic doses with bisphosphonates but also with denosumab. In osteoporosis ONJ seems to be very rare. Definition, pathogenesis, risk factors, prevention and treatment, and the freque...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:The influence of adolescent obesity on weight loss following bariatric surgery in adults has not been evaluated. The purpose of this study was to determine the impact of prior adolescent obesity on long-term weight changes following Roux-en-Y gastric bypass (RYGB) in adulthood. MATERIAL AND METHODS:This s...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Calcitonin gene-related peptide is an important vasodilator. It plays an important role in the metabolism of chewing muscles. The aim of the study was to evaluate the plasma level of CGRP in patients with myofascial pain (RDC/TMD Ia) and myofascial pain with limited opening (RDC/TMD Ib) before and after oc...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,随机对照试验
doi:10.5603/EP.2017.0025
更新日期:2017-01-01 00:00:00
abstract::Among genetic alterations most important for the initiation of papillary thyroid carcinoma (PTC) is mutation T1799A in the BRAF gene which is the most frequent event (54.5%) in this type of thyroid cancer. It is seen in all stages, from microcarcinoma through clinically overt disease to anaplastic cancer. It has been ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2006-07-01 00:00:00
abstract::The World Health Organization (WHO) issued a recommendation (Technical Consultation: Paris 2006, Luxembourg 2007) that salt consumption, as a risk factor for hypertension, atherosclerosis, myocardial infarction, stroke, and select cancers, should be restricted. The European Commission looked to adhere to this recommen...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2010-01-01 00:00:00
abstract::The present study is aimed to present the potential role of thyroid hormones (TH) in the pathogenesis of glioblastoma multiforme (GBM). In first part of this presentation the effect of general homeostasis of TH on GBM formation and course was shown. Then the evidence concerning present state of the knowledge about act...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.2015.0055
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Surgeries that spare the adrenal cortex during adrenalectomy have profound justification. Indications for this type of surgery are fairly strict, and more than 30 years of observations continuously verify the results of the procedure. MATERIAL AND METHODS:Of a total of 650 adrenalectomies, 22 (3.4%) were ...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2020.0033
更新日期:2020-01-01 00:00:00
abstract::The clinical manifestation of oncogenic osteomalacia includes bone pain, pathological fractures, general fatigue and muscle weakness. Such unspecific symptoms hinder the establishment of a proper diagnosis which very often requires long-lasting investigations with many diagnostic imaging methods. Here, we discuss di...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:To assess in a prospective study the course and the predictors of microalbuminuria in children and adolescents with type 1 diabetes. MATERIAL AND METHODS:438 children and adolescents who developed diabetes in the years 1985-2004 were followed for 9.2 ± 3.4 years from the diagnosis. Microalbuminuria was as...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.2014.0012
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Poorly differentiated thyroid carcinoma (PDTC, insular carcinoma) occurs rarely. It is described with more aggressive behaviour, poorer prognosis, and higher mortality than well differentiated thyroid carcinoma (WDTC). The aim of this study was to evaluate the clinical course of patients with PDTC, in addi...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract::There is a growing number of diseases which prevalence can be associated with vitamin D deficiency. The link between low cholecalciferol concentration and bone diseases is well established, however there is also data suggesting that it may influence development and progression of different cancers and autoimmune disea...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:
更新日期:2007-03-01 00:00:00
abstract:INTRODUCTION:Childhood obesity has been associated with the development of insulin resistance, potentially leading to several metabolic disorders. Osteocalcin has been reported to contribute to the regulation of glucose tolerance and insulin sensitivity. The purpose of this study was to examine the relationship between...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.2013.0016
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Multiple sclerosis (MS) is an autoimmune disease of the central nervous system. The exact aetiology is unknown. However, genetic and environmental factors are suggested to be involved in the pathogenesis of MS. Improper diet, resulting in obesity and metabolic syndrome, can contribute to this disease. Adip...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:10.5603/EP.a2020.0008
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Secretory products from adipocytes may contribute to deterioration in glycaemic control and increased insulin resistance (IR). Retinol-binding protein 4 (RBP-4) may increase IR in mice, with elevated levels in insulin-resistant mice and humans with obesity and type 2 diabetes. However, the mechanisms regul...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2008-07-01 00:00:00
abstract::We present a case of a woman with unique multisystem disorder--POEMS syndrome and endocrine abnormalities coexisting with it. The POEMS acronym comprises the dominant features: polyneuropathy, organomegaly, endocrinopathy, monoclonal protein (M protein), skin changes. Association between plasma cell dyscrasia and poly...
journal_title:Endokrynologia Polska
pub_type: 杂志文章
doi:
更新日期:2007-05-01 00:00:00
abstract:INTRODUCTION:To assess the rate of thyroid cancer and mortality rate in a cohort of patients who received RAI¹³¹ treatment for hyperthyroidism and to report the index cases' characteristics and management MATERIAL AND METHODS: A cohort of 264 patients who received RAI¹³¹ treatment for different causes of thyrotoxicosis...
journal_title:Endokrynologia Polska
pub_type: 杂志文章,评审
doi:10.5603/EP.a2017.0037
更新日期:2017-01-01 00:00:00