[Immunomorphometric study of megakaryocytes in patients with myelodysplastic syndrome].

Abstract:

:The purpose of this study was to analyse, by immunomorphometry, megakaryocytopoiesis in patients with myelodysplatsic syndrome. The results revealed that, in spite of marked megakaryocyte hyperplasia, patients with myelodysplastic syndrome suffer from severe peripheral thrombocytopenia. Megakaryocytes in myelodisplastic syndrome have, in average, small cellular and nuclear diameter and 35.3% of them (s. c. micromegakaryocyres) can be identified only by using immunohistochemical technique. In conclusion, there is severe maturation disturbancy, ineffectiveness and disregulation of megakaryocytopoiesis in myelodysplastic syndrome.

journal_name

Srp Arh Celok Lek

authors

Marisavljević D,Rolović Z

keywords:

subject

Has Abstract

pub_date

1992-11-01 00:00:00

pages

317-20

issue

11-12

eissn

0370-8179

issn

2406-0895

journal_volume

120

pub_type

杂志文章
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  • Changing the structure of the hospitalized patients at the Psychiatric Clinic Vrapce.

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  • [Obesity and chronic obstructive pulmonary disease].

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  • [Development of pharmacy in the Leskovac region for the period from liberation from the Turks until World War II].

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  • [Breech presentation at term: caesarean section or vaginal delivery?].

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