[Psoriatic onycho-pachydermo- periostitis].

abstract：:Rheumatoid arthritis (RA) is associated with a shortened life expectancy. Most premature deaths are caused by cardiovascular (CV) events; therefore it is of importance to consider the increased CV risk when treating RA patients. Traditional CV risk factors cannot fully explain the increased risk but the common underst...

journal_title：Zeitschrift fur Rheumatologie

authors： Pieringer H,Hoppe UC

更新日期：2013-05-01 00:00:00

abstract：:In order to measure therapeutic effects or assess disease course, outcomes measurement parameters are commonly used in patients with rheumatoid arthritis. From the patient's perspective, possibly the most important outcome measurement parameter is quality of life (QoL). QoL may be defined in terms of "health status" a...

journal_title：Zeitschrift fur Rheumatologie

authors： Stamm T

更新日期：2010-05-01 00:00:00

abstract：:In rheumatologic diseases magnet resonance imaging (MRI) is capable of depicting early inflammatory changes which are frequently missed by other imaging modalities. New MRI protocols and hardware, primarily whole-body MRI and low-field extremity MRI facilitate the use of MRI in rheumatology patients. The increasing nu...

journal_title：Zeitschrift fur Rheumatologie

authors： Buchbender C,Schneider M,Ostendorf B

更新日期：2013-03-01 00:00:00

abstract：:Due to the relative increase of age-diabetes and to the different forms of rheumatic diseases, long-term medicament therapy and the question of possible interactions between oral antidiabetic drugs ( OAD ) and nonsteroidal anti-inflammatory drugs (NSAID) become more important. Unfortunately there exist studies on most...

journal_title：Zeitschrift fur Rheumatologie

authors： Knüsel O

更新日期：1984-03-01 00:00:00

abstract：:Health services research in rheumatology investigates the healthcare needs, the quality of care and trends in healthcare for patients with musculoskeletal disorders. Using rheumatoid arthritis (RA) as an example, key results of health services research during the last 25 years are summarized. There are currently appro...

journal_title：Zeitschrift fur Rheumatologie

authors： Zink A

更新日期：2014-03-01 00:00:00

abstract：:An appropriate treatment of elderly rheumatic patients implements comprehensive diagnostics and exclusion diagnostics of e.g. coronary heart disease, osteoporosis, renal failure, diabetes mellitus type 2 and thyroid gland dysfunction. Furthermore, the complex disease situation might require the integration of other fa...

journal_title：Zeitschrift fur Rheumatologie

authors： Lakomek HJ,Brabant T,Lakomek M,Lüttje D

更新日期：2013-08-01 00:00:00

abstract：:Light and electron microscopic investigations of joint cartilage in 13 cases of septic arthritis revealed sites of cartilaginous matrix infiltrated with polymorphonuclear granulocytes. This finding confirms rather unknown morphological works done by investigators on this diseases in the late 19th and beginning of the ...

journal_title：Zeitschrift fur Rheumatologie

authors： Gauger M,Mohr W

更新日期：1995-07-01 00:00:00

abstract：:The diagnosis of rheumatoid arthritis has been hampered by the lack of a truly disease-specific serologic marker. Thus, despite its moderate specificity rheumatoid factor (RF) is still the only established marker antibody for RA and among the diagnostic criteria of the American College of Rheumatology the only serolog...

journal_title：Zeitschrift fur Rheumatologie

authors： Steiner G,Smolen JS

更新日期：2002-12-01 00:00:00

abstract：:For a long time, most of the infectious diseases seemed to have become under control. In particular, vaccinations have contributed to this development. In recent years newly occurring bacterial infections caused by multidrug-resistant pathogens and viral infections, such as the chikungunya virus, influenza epidemics a...

journal_title：Zeitschrift fur Rheumatologie

authors： Kneitz C,Müller-Ladner U

更新日期：2020-11-01 00:00:00

abstract：:Cell-based therapeutical approaches are already in clinical use and are attracting growing interest for the treatment of joint defects. Mesenchymal stem and precursor cells (MSC) cover a wide range of properties that are useful for the regeneration process of bone and cartilage defects. The following article is an ove...

journal_title：Zeitschrift fur Rheumatologie

authors： Dehne T,Tschirschmann M,Lauster R,Sittinger M

更新日期：2009-05-01 00:00:00

abstract：:A dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis was found in animal models of chronic inflammatory diseases, and the defect was located in more central portions of the HPA axis. This defect of neuroendocrine regulatory mechanisms contributes to the onset of the model disease. Since these first observati...

journal_title：Zeitschrift fur Rheumatologie

authors： Straub RH,Schölmerich J,Zietz B

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Leukotrienes and prostaglandines are important mediators of inflammation. While prostaglandine synthesis can be influenced by NSAIDs therapeutical approaches to the 5-lipoxygenase pathway are rare. Resinous extracts of Boswellia serrata (H15, indish incense), known from traditional ayurvedic medicine, decrea...

journal_title：Zeitschrift fur Rheumatologie

authors： Sander O,Herborn G,Rau R

更新日期：1998-02-01 00:00:00

abstract：AIM:Our aim was to adapt and implement the evidence based recommendations for the management of ankylosing spodylitis (AS) of the "Assessments in AS" (ASAS) International Working Group together with the European League Against Rheumatism (EULAR) within the framework of a competence network (CN) in rheumatology in the G...

journal_title：Zeitschrift fur Rheumatologie

authors： Braun J,Zochling J,Märker-Hermann E,Stucki G,Böhm H,Rudwaleit M,Zeidler H,Sieper J

更新日期：2006-12-01 00:00:00

abstract：:Rheumatoid vasculitis usually occurs on the background of seropositive rheumatoid arthritis, although in rare cases the patients can be seronegative. We report a woman with seronegative rheumatoid arthritis with rheumatoid vasculitis who developed toxic epidermal necrolysis involving most of her body surface area, whi...

journal_title：Zeitschrift fur Rheumatologie

authors： Chowdhury AC,Misra DP,Patro PS,Agarwal V

更新日期：2016-03-01 00:00:00

abstract：:The German Rheuma-Liga as the largest patient organisation presents the different ways of informing patients. Patient- education-programs are presented, with a program focussing on social and psychological issues in particular. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Cattelaens K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To investigate the association between HLA‑G polymorphisms and systemic lupus erythematosus (SLE) susceptibility as well as the relationship between circulating soluble HLA‑G (sHLA‑G) levels and SLE. METHODS:A meta-analysis was performed to investigate the relationships between HLA‑G 14-bp insertion (I)/dele...

journal_title：Zeitschrift fur Rheumatologie

authors： Bae SC,Lee YH

更新日期：2020-04-09 00:00:00

abstract：:The assessment of off-label medications is one of the most common reasons for assessment of drugs for individual patients in the German medical services. Tension is not uncommon because of great expectations of patients and doctors on the one hand and the requirements of the law on the other. They often do not match. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Grell L,Rieger M

更新日期：2012-02-01 00:00:00

abstract：:From the about 400 virus species known to cause illness in man, only a small but growing list of representatives are able to induce arthritis. Although virus-associated arthritides are mostly of acute and short-living type, some patients develop long-lasting or even chronic joint inflammation. The viral or host factor...

journal_title：Zeitschrift fur Rheumatologie

authors： Saal JG

更新日期：1995-11-01 00:00:00

abstract：:This review presents an overview of the range of imaging modalities used in the diagnostic evaluation of patients with psoriatic arthritis (PsA). Conventional radiography is used to detect structural changes of the joints and tendon attachments. These changes occur late in the course of PsA hence conventional radiogra...

journal_title：Zeitschrift fur Rheumatologie

authors： Hermann KG,Ohrndorf S,Werner SG,Finzel S,Backhaus M

更新日期：2013-10-01 00:00:00

abstract：:Rheumatoid arthritis (RA) represents an autoimmune disease affecting mostly joints, in particular small finger and toe joints. In addition RA can show extra-articular manifestations in many organs. Information on the frequency of extra-articular manifestations (EAMs) in RA varies greatly in different publications from...

journal_title：Zeitschrift fur Rheumatologie

authors： Baerwald C,Kneitz C,Bach M,Licht M

更新日期：2012-12-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic autoimmune disease of still unknown etiology that results in characteristic destructive changes of the joints. Research of the past years has demonstrated that synovial fibroblasts play a central role in the initiation and perpetuation of these destructive changes. Stimulation of...

journal_title：Zeitschrift fur Rheumatologie

authors： Korb A,Peters M,Meinecke I,Pap T

更新日期：2007-07-01 00:00:00

abstract：:When patents expire, usually after 10 years in Germany, generic medicines routinely enter the market in place of conventional medications leading to significant reductions in prices. Currently the first biologicals are approaching patent expiry. Because of the biochemical complexities truly identical imitators are unr...

journal_title：Zeitschrift fur Rheumatologie

authors： Aringer M,Dörner T

更新日期：2013-11-01 00:00:00

abstract：:Osteoarthritis (OA) is the most common cause of functional disability in the elderly. Pain and loss of motion induce a vicious circle, leading to instability, frailty and ultimately invalidity. Currently, there is no treatment to reverse or slow the disease progression to a clinically meaningful extent. Thus, the prim...

journal_title：Zeitschrift fur Rheumatologie

authors： Brabant T,Stichtenoth D

更新日期：2005-10-01 00:00:00

abstract：:A multicentric post-marketing surveillance study over 7 years including 5,124 patients is presented. According to clinical and laboratory data, the drug D-penicillamine was effective, with a tendency of loss of efficacy after therapy of 5 years or longer. Response was better in the early stage of the disease. Side eff...

journal_title：Zeitschrift fur Rheumatologie

authors： Kashiwazaki S

更新日期：1988-01-01 00:00:00

abstract：:Arthrosis deformans is a common disease worldwide with a high prevalence among all ethnic groups. All joints may be affected and genetic factors influence the onset of the disease. The main symptoms include pain and increasing immobility over the course of the illness. Treatment in early stages is conservative. In the...

journal_title：Zeitschrift fur Rheumatologie

authors： Rehart S,Lehnert H

更新日期：2008-07-01 00:00:00

abstract：:Autoimmune rheumatic diseases (ARD) affect young females during childbearing age. Over the last decades, improvements in survival as well as quality of life in patients affected with ARD have led to an increased number of pregnancies observed during the course of such diseases. Systemic lupus erythematosus (SLE) is th...

journal_title：Zeitschrift fur Rheumatologie

authors： Doria A,Iaccarino L,Ghirardello A,Arienti S,Zampieri S,Rampudda ME,Tincani A,Todesco S

更新日期：2006-05-01 00:00:00

abstract：:In recent years the great progress in knowledge on bone cell biology has allowed identification of molecular structures that can be targeted with pinpoint precision (druggable targets). Osteoclasts are regulated via the RANK-RANK-ligand (RANKL) signaling pathway and osteoblasts via the Wnt signaling pathway, both of w...

journal_title：Zeitschrift fur Rheumatologie

authors： Knauerhase A,Willenberg HS

更新日期：2016-06-01 00:00:00

abstract：:Serum protein binding of naproxen is considerably reduced in patients with renal insufficiency. The hypothetical plasma concentration at time zero and the half life are not significantly altered in uremic patients in comparison with healthy subjects when the drug is given orally. This suggests an increased pharmacodyn...

journal_title：Zeitschrift fur Rheumatologie

authors： Held H

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:Since the introduction of biologic treatment in rheumatoid arthritis (RA), disease activity and treatment modalities have changed substantially. The current provision and developments in recent years are analyzed with annual data from the National Database of the Collaborative Arthritis Centers in Germany. ...

journal_title：Zeitschrift fur Rheumatologie

authors： Albrecht K,Huscher D,Eidner T,Kleinert S,Späthling-Mestekemper S,Bischoff S,Zink A

更新日期：2017-02-01 00:00:00

abstract：:Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) require a differentiated therapeutic approach depending on the degree of organ dysfunction and disease activity. In organ dysfunction and life-threatening AAV cyclophosphamide and rituximab are recommended for the induction of remission. For remi...

journal_title：Zeitschrift fur Rheumatologie

authors： Schinke S,Riemekasten G,Lamprecht P

更新日期：2017-02-01 00:00:00