Acceleration of invasive activity via matrix metalloproteinases by transfection of the estrogen receptor-alpha gene in endometrial carcinoma cells.

abstract：:The role of plasma oxidant-antioxidant status in survival after breast cancer surgery was investigated in a cohort of patients (n = 363) hospitalized in Southern France between 1989 and 1992. The median follow-up was 8 years after surgery for histologically confirmed breast cancer. Plasma analyses were performed after...

journal_title：International journal of cancer

authors： Saintot M,Mathieu-Daude H,Astre C,Grenier J,Simony-Lafontaine J,Gerber M

更新日期：2002-02-10 00:00:00

abstract：:CD16 surface antigens represent activatory molecules in CD3-16+ NK cells. In order to target NK cells against relatively NK-resistant ovarian carcinomas, we used an anti-CD16 monoclonal antibody (MAb) (VD4), together with an anti-ovarian carcinoma-associated antigen (MOV19), to construct biMAbs. To this end, hybrid hy...

journal_title：International journal of cancer

authors： Ferrini S,Prigione I,Miotti S,Ciccone E,Cantoni C,Chen Q,Colnaghi MI,Moretta L

更新日期：1991-05-10 00:00:00

abstract：:The stability of a cloned murine tumor for sensitivity to NR was examined following growth in vivo in order to test the hypothesis that tumor progression proceeds through the generation and selection of variants. Clonal sensitivity to the [131I]-dUrd elimination assay of NR was assessed for the L5178Y-F9 tumor grown i...

journal_title：International journal of cancer

authors： Chow DA,Ray M,Greenberg AH

更新日期：1983-01-15 00:00:00

abstract：:The incidence of cervical adenocarcinoma (CA) is rising, whereas the incidence of cervical squamous cell carcinoma (CSCC) continues to decrease. However, it is still unclear whether different molecular characteristics underlie these 2 types of cervical carcinoma. To better understand the epigenetic characteristics of ...

journal_title：International journal of cancer

authors： Kang S,Kim JW,Kang GH,Lee S,Park NH,Song YS,Park SY,Kang SB,Lee HP

更新日期：2006-05-01 00:00:00

abstract：:IgG binding to purified mouse mammary tumor virus (MuMTV) was quantitated by an enzyme-linked immunoassay (ELISA) using sera from patients with breast cancer or benign breast disease, or from healthy age-matched controls. Significantly greater binding (p<0.01) was found in breast-cancer-derived sera than in the other ...

journal_title：International journal of cancer

authors： Witkin SS,Sarkar NH,Kinne DW,Good RA,Day NK

更新日期：1980-06-15 00:00:00

abstract：:We transduced a human gastric carcinoma cell line, HR, with the interleukin 2 (IL-2) gene. Stable HR transfectants secreted nanogram quantities of biologically active IL-2 and had significantly increased expression of IL-2 mRNA relative to that in parental cells. Expression of intracellular IL-2 protein was not quanti...

journal_title：International journal of cancer

authors： Nagashima S,Kashii Y,Reichert TE,Suminami Y,Suzuki T,Whiteside TL

更新日期：1997-07-03 00:00:00

abstract：:We have identified a novel membrane-type matrix metalloproteinase (MT-MMP) expressed on the cell surface and inducing activation of pro-gelatinase A in vitro. In this study, we further examined the possibility that MT-MMP is the activator of pro-gelatinase A in tumors as well as in vitro. Expression of MT-MMP mRNA was...

journal_title：International journal of cancer

authors： Tokuraku M,Sato H,Murakami S,Okada Y,Watanabe Y,Seiki M

更新日期：1995-10-20 00:00:00

abstract：:Lysyl oxidase (LOX), a copper-dependent amine oxidase, has been implicated in tumor suppression and cell growth regulation. The chromosomal locus of LOX, 5q23, is affected by loss of heterozygosity (LOH) in colon cancer, suggesting that the LOX gene could be affected by LOH and consequently, loss or reduction of LOX f...

journal_title：International journal of cancer

authors： Csiszar K,Fong SF,Ujfalusi A,Krawetz SA,Salvati EP,Mackenzie JW,Boyd CD

更新日期：2002-02-10 00:00:00

abstract：:Frequently, the number of circulating tumor cells (CTC) isolated in 7.5 mL of blood is too small to reliably determine tumor heterogeneity and to be representative as a "liquid biopsy". In the EU FP7 program CTCTrap, we aimed to validate and optimize the recently introduced Diagnostic LeukApheresis (DLA) to screen lit...

journal_title：International journal of cancer

authors： Andree KC,Mentink A,Zeune LL,Terstappen LWMM,Stoecklein NH,Neves RP,Driemel C,Lampignano R,Yang L,Neubauer H,Fehm T,Fischer JC,Rossi E,Manicone M,Basso U,Marson P,Zamarchi R,Loriot Y,Lapierre V,Faugeroux V,Oulhen

更新日期：2018-11-15 00:00:00

abstract：:Improved biomarkers for prostate cancer (PC) risk stratification are urgently needed. Here, we aimed to develop a novel multimarker model for prediction of biochemical recurrence (BCR) after curatively intended radical prostatectomy (RP), based on minimally invasive sampling of blood and urine. We initially measured t...

journal_title：International journal of cancer

authors： Fredsøe J,Rasmussen AKI,Mouritzen P,Borre M,Ørntoft T,Sørensen KD

更新日期：2019-11-01 00:00:00

abstract：:Evidence suggests that the majority of lung cancer patients have tumour-derived genetic alterations in circulating plasma DNA, and that this may be developed as a diagnostic tool. To this end, we have studied 60 individuals attending bronchoscopy clinic, with symptoms suspicious of lung cancer, for genetic alterations...

journal_title：International journal of cancer

authors： Allan JM,Hardie LJ,Briggs JA,Davidson LA,Watson JP,Pearson SB,Muers MF,Wild CP

更新日期：2001-02-01 00:00:00

abstract：:Insulin-like growth factor binding protein-3 (IGFBP-3) inhibits the mitogenic and antiapoptotic activity of insulin-like growth factor (IGF) by blocking the binding of IGF to its receptor. However, under certain circumstances, IGFBP-3 can enhance the activity of IGF by protecting IGF from degradation. More than half o...

journal_title：International journal of cancer

authors： Moon JW,Chang YS,Ahn CW,Yoo KN,Shin JH,Kong JH,Kim YS,Chang J,Kim SK,Kim HJ,Kim SK

更新日期：2006-01-15 00:00:00

abstract：:Using radioiodinated Staphylococcus aureus protein A [125I]SPA to measure syngeneic, allogeneic and heterogeneic IgG bound to murine tumor cells, we performed a serological analysis of surface antigens of 8 solid tumors and 2 leukemias of BALB/c mice (3 chemically-induced colon carcinomas, 3 chemically-induced sarcoma...

journal_title：International journal of cancer

authors： Cleveland PH,Belnap LP,Knotts FB,Nayak SK,Baird SM,Pilch YH

更新日期：1979-03-15 00:00:00

abstract：:Expression of the macrophage antigen CD163 in breast cancer cells is recently shown to be related to early distant recurrence and shortened survival. In this study, 163 patients with rectal cancer, included in the Swedish rectal cancer trial and followed up for a median of 71 months, were examined for the expression o...

journal_title：International journal of cancer

authors： Shabo I,Olsson H,Sun XF,Svanvik J

更新日期：2009-10-15 00:00:00

abstract：:Coffee has been proposed to decrease the circulating insulin and estrogen levels, which are related to the development of endometrial cancer. However, few studies have prospectively assessed the association between coffee consumption and endometrial cancer. We conducted a population-based prospective cohort study in 5...

journal_title：International journal of cancer

authors： Shimazu T,Inoue M,Sasazuki S,Iwasaki M,Kurahashi N,Yamaji T,Tsugane S,JPHC Study Group Members of the Japan Public Health Center-based Prospective Study.

更新日期：2008-11-15 00:00:00

abstract：:Bcl-2 expression is up-regulated in prostate cancer cells after androgen ablation and associated with development of androgen independence and chemoresistance. We recently reported that antisense Bcl-2 oligodeoxynucleotides (ODNs) delay progression to androgen independence in the androgen-dependent (AD) human LNCaP pr...

journal_title：International journal of cancer

authors： Leung S,Miyake H,Zellweger T,Tolcher A,Gleave ME

更新日期：2001-03-15 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, seem to have chemopreventive properties against several types of cancer, particularly colon cancer. Persons with rheumatoid arthritis, an autoimmune disease for which NSAIDs are used commonly, have been reported to be at lower risk of colon cancer but ...

journal_title：International journal of cancer

authors： Cerhan JR,Anderson KE,Janney CA,Vachon CM,Witzig TE,Habermann TM

更新日期：2003-09-20 00:00:00

abstract：:The International Classification of Childhood Cancer (ICCC) updates the widely used Birch and Marsden classification scheme. ICCC is based on the second edition of the International Classification of Diseases for Oncology (ICD-O-2). The purpose of the new classification is to accommodate important changes in recogniti...

journal_title：International journal of cancer

authors： Kramárová E,Stiller CA

更新日期：1996-12-11 00:00:00

abstract：:A-kinase anchoring protein 3 (AKAP3) is a sperm protein and its expression appears to be restricted to the testis in normal adult tissues. We investigated AKAP3 mRNA expression in 20 normal ovaries and 54 ovarian cancers of different histological types, grades and stages by reverse transcription-polymerase chain react...

journal_title：International journal of cancer

authors： Hasegawa K,Ono T,Matsushita H,Shimono M,Noguchi Y,Mizutani Y,Kodama J,Kudo T,Nakayama E

更新日期：2004-01-01 00:00:00

abstract：:We applied a strategy that utilized a combination of systematic gene expression analysis with various tissues and immunological detection with sera from melanoma patients to identify melanoma antigens expressed preferentially in melanoma and melanocytes. We selected 101 genes by comparing cDNA profiles obtained by Gen...

journal_title：International journal of cancer

authors： Inozume T,Matsuzaki Y,Kurihara S,Fujita T,Yamamoto A,Aburatani H,Shimada S,Kawakami Y

更新日期：2005-03-20 00:00:00

abstract：:Prostate-specific antigen (PSA) has been characterized as a specific prostate marker, although recent studies have suggested the existence of PSA of nonprostatic sources. We have assessed the presence of PSA by an ultrasensitive assay in 276 serum and nonserum samples from women. Our data show the presence of PSA in 9...

journal_title：International journal of cancer

authors： Filella X,Molina R,Alcover J,Carretero P,Ballesta AM

更新日期：1996-11-15 00:00:00

abstract：:Using comparative genomic hybridisation, we investigated chromosomal imbalances in 28 cases of thymic epithelial neoplasms including type A, B2, B3, the A component of type AB and different subtypes of type C thymoma. To identify different patterns of chromosomal aberrations associated with the biological behaviour an...

journal_title：International journal of cancer

authors： Penzel R,Hoegel J,Schmitz W,Blaeker H,Morresi-Hauf A,Aulmann S,Hecker E,Mechtersheimer G,Otto HF,Rieker RJ

更新日期：2003-07-01 00:00:00

abstract：:HPP1 is a recently discovered gene that is epigenetically silenced in a number of tumor types, suggesting a potential role as a tumor suppressor. However, whether HPP1 has tumor suppressor activity is not clearly known. We have sought to investigate the effects of HPP1 on tumor growth and survival and to identify sign...

journal_title：International journal of cancer

authors： Elahi A,Zhang L,Yeatman TJ,Gery S,Sebti S,Shibata D

更新日期：2008-04-01 00:00:00

abstract：:The results of a survey of a population with a high incidence of oral and oesophageal cancer are presented. The population under study appears to have several epidemiologic characteristics, some of which may be associated with a high incidence of oral and oesophageal cancer. A remarkably high proportion (41%) of the m...

journal_title：International journal of cancer

authors： Zaridze DG,Blettner M,Trapeznikov NN,Kuvshinov JP,Matiakin EG,Poljakov BP,Poddubni BK,Parshikova SM,Rottenberg VI,Chamrakulov FS

更新日期：1985-08-15 00:00:00

abstract：:In our study, we aimed to investigate the expression of N-cadherin and E-cadherin and their dependency on epithelial-mesenchymal transition regulators SNAI1, SIP1 and TWIST in human colon cancer. Expression of E-cadherin and N-cadherin was examined by immunohistochemistry in 80 colon carcinomas by using paraffin embed...

journal_title：International journal of cancer

authors： Rosivatz E,Becker I,Bamba M,Schott C,Diebold J,Mayr D,Höfler H,Becker KF

更新日期：2004-09-20 00:00:00

abstract：:Human B- or T-cell lymphoma lines and primary murine lymphomas were treated with DNA oligonucleotides homologous to the telomere (TTAGGG repeat; "T-oligo"), either alone or in combination with standard, widely-used anticancer chemotherapeutic agents. T-oligo induces cell cycle arrest and apoptosis in cultured human or...

journal_title：International journal of cancer

authors： Longe HO,Romesser PB,Rankin AM,Faller DV,Eller MS,Gilchrest BA,Denis GV

更新日期：2009-01-15 00:00:00

abstract：:Human mammary carcinoma cell lines (MCF-7) were analysed for their hormone sensitivity before and after transfection with a v-Ha-ras oncogene or with a neomycin-resistance gene followed by selection in vitro or in vivo. Our aim was to test how the expression of the ras oncogene would influence the estradiol sensitivit...

journal_title：International journal of cancer

authors： Van Roy F,Mareel M,Vleminckx K,Beyaert R,Fiers W,Devleeschouwer N,Muquardt C,Legros N,Bracke M,Leclercq G

更新日期：1990-09-15 00:00:00

abstract：:Immune cells in tumor microenvironment play a prominent role in tumor progression and metastasis. MicroRNA-155 (miR-155) represents an important player in innate and adaptive immunity by regulating differentiation, maturation and activation of macrophages, dendritic cells, B cells and T cells. However, the role of miR...

journal_title：International journal of cancer

authors： Wang J,Yu F,Jia X,Iwanowycz S,Wang Y,Huang S,Ai W,Fan D

更新日期：2015-03-15 00:00:00

abstract：:We have obtained a novel multidrug resistant cell line, derived from HT29 G(+) human colon carcinoma cells, by selection with gradually increasing concentrations of the anti-mitotic, microtubule-disrupting agent colchicine. This HT29(col) cell line displayed a 25-fold increase in colchicine resistance and exhibited cr...

journal_title：International journal of cancer

authors： Kok JW,Veldman RJ,Klappe K,Koning H,Filipeanu CM,Müller M

更新日期：2000-07-15 00:00:00

abstract：:A novel cell culture system is reported for the growth of ovarian tumors. Two approaches were developed to isolate tumor cells, one for ovarian carcinomas and the other for benign cystomas or borderline cystadenomas, which yield virtually pure tumor-cell clusters. The plating efficiency exceeded 10% in approximately 8...

journal_title：International journal of cancer

authors： Balconi G,Broggini M,Erba E,D'Incalci M,Colombo N,Mangioni C,Bertolero F

更新日期：1988-06-15 00:00:00