Abstract：
:Epinephrine has been administered as a drug essential for cardiopulmonary resuscitation (CPR). Recently, vasopressin has been reported to be more effective than epinephrine for CPR in a ventricular fibrillation (VF) model. As a different myocardial pathology is speculated to exist between the VF model and the asphyxia model, we investigated whether vasopressin is also effective in a rat asphyxia model. Twenty-one Sprague-Dawley male rats were divided into three groups: vasopressin 0.8 U/kg (Vaso-Gr), epinephrine 0.05 mg/kg (Epi-Gr), and saline same volume as the other two drugs (Sal-Gr). Five minutes after suffocation induced by obstruction of the tracheal tube, CPR was performed using each drug. Although only one animal survived (17%) in the Sal-Gr, 6/7 (85%) survived in both Vaso-Gr and Epi-Gr (P<0.01). Vasopressin is as effective as epinephrine for CPR in asphyxia-induced rats.
journal_name
Resuscitationjournal_title
Resuscitationauthors
Kono S,Bito H,Suzuki A,Obata Y,Igarashi H,Sato Sdoi
10.1016/s0300-9572(01)00447-6keywords:
subject
Has Abstractpub_date
2002-02-01 00:00:00pages
215-9issue
2eissn
0300-9572issn
1873-1570pii
S0300957201004476journal_volume
52pub_type
杂志文章相关文献
RESUSCITATION文献大全abstract：OBJECTIVE:To develop statistical tools that use combined initial survival data and post-resuscitation survival data to test the null hypothesis that true, population-wide outcomes following experimental CPR interventions are not different from control. METHOD:A new test statistic, d(2), for evaluating Type 1 error is ...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2007.04.026
更新日期：2007-11-01 00:00:00
abstract：BACKGROUND:Point-of-care ultrasound has been suggested to improve outcomes from advanced cardiac life support (ACLS), but no large studies have explored how it should be incorporated into ACLS. Our aim was to determine whether cardiac activity on ultrasound during ACLS is associated with improved survival. METHODS:We ...
journal_title：Resuscitation
pub_type： 杂志文章,多中心研究
doi：10.1016/j.resuscitation.2016.09.018
更新日期：2016-12-01 00:00:00
abstract：:ATP-MgCl2 treatment has been found to be a promising intervention in many models of hypoxic/ischemic injury. In this study, the effect of pre-treatment with ATP-MgCl2 on the hemodynamic response to asphyxia in the rat was examined. Rats were anesthetized with halothane and N2O2. A tracheostomy and femoral artery and v...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/0300-9572(93)90089-9
更新日期：1993-04-01 00:00:00
abstract：AIM OF THE STUDY:To investigate whether pure self-learning without instructor support, resulted in the same BLS-competencies as facilitator-led learning, when using the same commercially available video BLS teaching kit. METHODS:First-year medical students were randomised to either BLS self-learning without supervisio...
journal_title：Resuscitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.resuscitation.2018.02.031
更新日期：2018-05-01 00:00:00
abstract：AIM:We presented the cut-off value of a diffusion-weighted image (DWI) scoring system to predict poor neurologic outcome using DWI taken 72-96 h after out-of-hospital cardiac arrest (OHCA) patients underwent target temperature management (TTM). METHODS:This was a prospective single-centre observational study, conducte...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2020.08.130
更新日期：2020-12-01 00:00:00
abstract：AIM:Survival after out-of-hospital cardiac arrest (OOHCA) varies between regions, but the contribution of different factors to this variability is unknown. This study examined whether survival to hospital discharge was related to receiving hospital characteristics, including bed number, capability of performing cardiac...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2009.12.006
更新日期：2010-05-01 00:00:00
abstract：OBJECTIVE:In susceptibility-weighted imaging (SWI) in the normal brain, cortical veins appear hypointense due to paramagnetic properties of deoxy-hemoglobin. Global cerebral anoxia decreases cerebral oxygen metabolism, thereby increasing oxy-hemoglobin levels in cerebral veins. We hypothesized that a lower cerebral oxy...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2014.12.024
更新日期：2015-03-01 00:00:00
abstract：AIM:To mimic chest compression during cardiopulmonary resuscitation (CPR), this study aimed to produce time-resolved 3D (volumetric) reformats of thoracic and upper abdominal tissue movement during incremental closed chest compression/decompression from 0 to 8 to 0 cm. METHODS:Sequential angiography enhanced computed ...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2020.05.037
更新日期：2020-08-01 00:00:00
abstract：:Recent experimental and clinical studies of cardiac arrest, suggesting a brain damage ameliorating effect of thiopental loading, stimulated the development of an international randomized clinical trial of brain resuscitation. Twelve collaborating hospitals in 9 countries are testing the efficacy of post-cardiac arrest...
journal_title：Resuscitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0300-9572(82)90022-3
更新日期：1982-06-01 00:00:00
abstract：AIM:To determine the feasibility of transporting post-cardiac arrest patients to tertiary-care facilities, the rate of re-arrest, and the rate of critical events during critical care transport team (CCTT) care. METHODS:Retrospective chart review of cardiac arrest patients transported via CCTT between 1/1/2001 and 5/31...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2010.04.012
更新日期：2010-08-01 00:00:00
abstract：AIM OF THE STUDY:Serum glial fibrillary acidic protein (GFAP) has recently been identified as a specific predictor of brain damage and neurological outcome in patients with head trauma. In this study, serum GFAP was assessed as a predictor of neurological outcome in post-cardiac-arrest (PCA) patients. METHODS:This stu...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2009.04.003
更新日期：2009-07-01 00:00:00
abstract：AIM:To analyze the relationship between the depth of the chest compressions and the fluctuation caused in the thoracic impedance (TI) signal in out-of-hospital cardiac arrest (OHCA). The ultimate goal was to evaluate whether it is possible to identify compressions with inadequate depth using information of the TI wavef...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2013.12.035
更新日期：2014-05-01 00:00:00
abstract：:Consecutive admissions to two pediatric intensive care units (PICUs) in France (n = 93) and the United States (n = 248) were compared using admission demographics, and daily therapeutic and severity of illness data. Analysis of the major demographic characteristics revealed that patients in the French PICU were younge...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/0300-9572(89)90066-x
更新日期：1989-04-01 00:00:00
abstract：:Teleologically, pain is of paramount importance for survival and induces the organism to cope in an active way with aggressions from a basically hostile environment. While the activation of endogenous analgesic (opioid) systems typically occurs in conditions of surrender (pre-terminal conditions, sustained tortures, e...
journal_title：Resuscitation
pub_type： 杂志文章,评审
doi：10.1016/0300-9572(94)00863-b
更新日期：1995-08-01 00:00:00
abstract：:This study evaluated the effects of sodium-hydrogen exchanger (NHE1) inhibition on enhancing fluid resuscitation outcomes in traumatic hemorrhagic shock, and examined the mechanisms related to NHE1 inhibitor-induced protection and recovery from hemorrhagic shock. Traumatic hemorrhage was modeled in anesthetized pigs b...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2011.11.025
更新日期：2012-06-01 00:00:00
abstract：AIM:Cardiopulmonary resuscitation (CPR) quality affects survival after cardiac arrest. We aimed to investigate if a smartwatch with real-time feedback can improve CPR quality by healthcare professionals. METHODS:An app providing real-time audiovisual feedback was developed for a smartwatch. Emergency Department (ED) p...
journal_title：Resuscitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.resuscitation.2019.04.050
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:Efficient trials of interventions for patients with out-of-hospital cardiac arrest (OHCA) should have adequate but not excess power to detect a difference in outcomes. The minimum clinically important difference (MCID) is the threshold value in outcomes observed in a trial at which providers should choose to...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2016.08.004
更新日期：2016-10-01 00:00:00
abstract：:The demands for an optimal ventilation apparatus are that it can be easily handled, achieves a sufficiently high ventilation volume, and minimizes gastric inflation. Our aim was therefore to carry out a study in a training mannikin to find out whether the Oxylator EM100, compared with the bag, obtains improved ventila...
journal_title：Resuscitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0300-9572(97)00091-9
更新日期：1998-01-01 00:00:00
abstract：UNLABELLED:The optimal intravenous catheterisation site for emergencies is unknown. The external jugular vein might be preferable route compared to cubital veins in emergencies due to more rapid circulation time to heart and faster cardiac responses. However, the feasibility of the different venous catheterisation site...
journal_title：Resuscitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.resuscitation.2009.08.026
更新日期：2009-12-01 00:00:00
abstract：AIM:Increases in serum cytokines have been reported after successful resuscitation from prolonged ventricular fibrillation (VF). Pro-inflammatory cytokines can stimulate inducible nitric oxide synthase (iNOS) to produce excessive levels of nitric oxide (NO). High levels of both myocardial inflammatory cytokines and nit...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2008.01.026
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVE:the aim of the study is to investigate the effect of thrombolytic therapy on neurological outcome in patients after cardiac arrest due to acute myocardial infarction. Laboratory investigations have demonstrated that thrombolytic therapy after cardiopulmonary resuscitation improves neurological function. METH...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/s0300-9572(01)00432-4
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVE:To describe our outcomes using thrombolysis during the cardiopulmonary resuscitation (CPR) of patients in cardiorespiratory arrest (CA) caused by fulminant pulmonary embolism (FPE). DESIGN:A case series. SETTING:Intensive care units of a district hospital and a referral centre. PATIENTS:Six patients that s...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/s0300-9572(01)00384-7
更新日期：2001-10-01 00:00:00
abstract：:This is the summary publication of the International Liaison Committee on Resuscitation's 2020 International Consensus on First Aid Science With Treatment Recommendations. It addresses the most recent published evidence reviewed by the First Aid Task Force science experts. This summary addresses the topics of first ai...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2020.09.016
更新日期：2020-11-01 00:00:00
abstract：:Little information has been published on the uptake of cardiopulmonary resuscitation (CPR) training in rural areas or on the potential to associate a health promotion message with skills training. This paper describes CPR instructor and community training programmes in Ireland. Public interest in these programmes has ...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/s0300-9572(96)01005-2
更新日期：1996-12-01 00:00:00
abstract：AIM OF THE STUDY:Airway management in an out-of-hospital setting is a critical and demanding skill. Previous studies evaluated the intubating laryngeal mask airway (ILMA) as a valuable tool in this area. The LMA CTrach Laryngeal Mask Airway (CTrach) may increase intubation success. Therefore, we evaluated the CTrach as...
journal_title：Resuscitation
pub_type： 临床试验,杂志文章
doi：10.1016/j.resuscitation.2008.06.020
更新日期：2008-11-01 00:00:00
abstract：INTRODUCTION:Triage after resuscitation from cardiac arrest is hindered by reliable early estimation of brain injury. We evaluated the performance of a triage model based on early bispectral index (BIS) findings and cardiac risk classes. METHODS:Retrospective evaluation of serial patients resuscitated from cardiac arr...
journal_title：Resuscitation
pub_type： 杂志文章
doi：10.1016/j.resuscitation.2014.04.016
更新日期：2014-08-01 00:00:00
abstract：:Cardiac arrest causes whole body ischaemic injury and cellular death. Successful cardiopulmonary resuscitation (CPR) can subsequently lead to a global reperfusion phenomenon with a paradoxically increased rate of cellular death. Interventions that decrease the ischaemia-reperfusion injury may be useful in the treatmen...
journal_title：Resuscitation
pub_type： 杂志文章,评审
doi：10.1016/j.resuscitation.2010.06.016
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVES:The main pathogenesis of acute lung injury induced by haemorrhagic shock is inflammation. BML-111, a lipoxinA(4)-receptor agonist, promotes acute inflammatory resolution. We sought to elucidate whether BML-111 protects haemorrhagic shock-induced acute lung injury in rats. METHODS:Thirty two adult male rats ...
journal_title：Resuscitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.resuscitation.2011.12.035
更新日期：2012-07-01 00:00:00
abstract：:Almost any insult to the body can set in motion the sequence of physiologic and biochemical changes leading to shock. In the absence of effective treatment widespread disruption of the body's biological mechanisms inevitably follows. This review will describe some of cellular and subcellular disturbances associated wi...
journal_title：Resuscitation
pub_type： 杂志文章,评审
doi：10.1016/0300-9572(89)90055-5
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:During cardiac arrest and after successful resuscitation a continuum of ischaemia-reperfusion injury develops. Mild hypothermia exerts protective effects in the postresuscitation phase but also alters CO₂ production and solubility, which may lead to deleterious effects if overlooked when adjusting the ventil...
journal_title：Resuscitation
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.resuscitation.2011.04.022
更新日期：2011-09-01 00:00:00
