当前位置： SCI文献检索 > RESUSCITATION期刊下所有文献 > An international collaborative clinical study mechanism for resuscitation research.

An international collaborative clinical study mechanism for resuscitation research.

Abstract：

:Recent experimental and clinical studies of cardiac arrest, suggesting a brain damage ameliorating effect of thiopental loading, stimulated the development of an international randomized clinical trial of brain resuscitation. Twelve collaborating hospitals in 9 countries are testing the efficacy of post-cardiac arrest thiopental loading (30 mg/kg body wt). The methodology for assessing insult and outcome data, as well as risk and benefit monitoring, is described. This clinical trial will be completed in 1983 and is expected to provide valuable data about the efficacy of thiopental loading. The study mechanism is now well-established and ready for the evaluation of future promising brain resuscitation therapies.

journal_name

Resuscitation

journal_title

Resuscitation

authors

Abramson NS,Safar P,Detre K,Kelsey S,Reinmuth O,Snyder J

doi

10.1016/0300-9572(82)90022-3

subject

Has Abstract

pub_date

1982-06-01 00:00:00

pages

141-7

issue

2

eissn

0300-9572

issn

1873-1570

pii

0300-9572(82)90022-3

journal_volume

10

pub_type

临床试验,杂志文章,随机对照试验

相关文献

RESUSCITATION文献大全
  • Work factors associated with return to work in out-of-hospital cardiac arrest survivors.

    abstract：INTRODUCTION:Although the survival rate after out-of-hospital cardiac arrest (OHCA) has increased over time, little is known about the return to work of OHCA survivors. We aim to evaluate prevalence and factors associated with return to work (RTW) in OHCA survivors. PATIENTS AND METHODS:All consecutive OHCA survivors ...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2018.05.021

    authors： Descatha A,Dumas F,Bougouin W,Cariou A,Geri G

    更新日期：2018-07-01 00:00:00

  • Adenosine by aortic flush fails to augment the brain preservation effect of mild hypothermia during exsanguination cardiac arrest in dogs - an exploratory study.

    abstract：:Most trauma cases with rapid exsanguination to cardiac arrest (CA) in the field, as well as many cases of normovolemic sudden cardiac death are 'unresuscitable' by standard cardiopulmonary-cerebral resuscitation (CPCR). We are presenting a dog model for exploring pharmacological strategies for the rapid induction by a...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/s0300-9572(99)00164-1

    authors： Woods RJ,Prueckner S,Safar P,Takasu A,Tisherman SA,Jackson EK,Radovsky A,Kochanek P,Behringer W,Stezoski SW,Hans R

    更新日期：2000-03-01 00:00:00

  • Rescue percutaneous coronary intervention during cardiopulmonary resuscitation.

    abstract：:If sudden cardiac arrest occurs during cardiac catheterization, the underlying coronary condition may be defined immediately by coronary angiography. This may, in turn, allow a lifesaving attempt of percutaneous coronary intervention (PCI). We report on two patients with critical proximal disease of the left coronary ...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2003.12.020

    authors： Azman KJ,Gorjup V,Noc M

    更新日期：2004-05-01 00:00:00

  • Effect of mild hypothermia on ischemia-induced release of endothelin-1 in dog brain.

    abstract：:Endothelin-1 (ET-1) plays an important role in the physiologic or pathophysiologic regulation of cerebral circulation. To evaluate the effect of mild hypothermia on the cerebral concentration of ET-1 and on the cerebral metabolism of oxygen after complete global cerebral ischemia, we occluded the ascending aorta and c...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/0300-9572(95)00907-8

    authors： Takasu A,Yagi K,Okada Y

    更新日期：1996-02-01 00:00:00

  • Comparison of non-calibrated pulse-contour analysis with continuous thermodilution for cardiac output assessment in patients with induced hypothermia after cardiac arrest.

    abstract：AIM:Induced mild hypothermia after cardiac arrest interferes with clinical assessment of the cardiovascular status of patients. In this situation, non-invasive cardiac output measurement could be useful. Unfortunately, arterial pulse contour is altered by temperature, and the performance of devices using arterial blood...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2010.12.015

    authors： Haenggi M,Barthelmes D,Ulmer H,Takala J,Jakob SM

    更新日期：2011-04-01 00:00:00

  • Prognostic value of cell-free DNA in plasma of out-of-hospital cardiac arrest survivors at ICU admission and 24h post-admission.

    abstract：:Cell-free DNA has been associated with outcome in several acute conditions including two reports concerning the outcomes after cardiac arrest that found association of circulating DNA quantities at admission with mortality. The origins of cell-free DNA are primarily necrosis and apoptosis, which in cardiac arrest occu...

    journal_title：Resuscitation

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.resuscitation.2013.10.008

    authors： Gornik I,Wagner J,Gašparović V,Miličić D,Degoricija V,Skorić B,Gornik O,Lauc G

    更新日期：2014-02-01 00:00:00

  • Percutaneous venoarterial extracorporeal membrane oxygenation for emergency mechanical circulatory support.

    abstract：:In this retrospective study we report our initial experience with percutaneous venoarterial extracorporeal membrane oxygenation in the emergency treatment of intractable cardiogenic shock or pulseless electrical activity. Between January 1994 and July 1995, percutaneous venoarterial extracorporeal membrane oxygenation...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/s0300-9572(96)00989-6

    authors： Mair P,Hoermann C,Moertl M,Bonatti J,Falbesoner C,Balogh D

    更新日期：1996-11-01 00:00:00

  • The effect of cytidine diphosphate choline on in vivo lung mechanics in premature newborn rabbits.

    abstract：:The influence of CDP-choline on neonatal lung adaptation was studied in premature rabbit neonates, delivered on day 28 of gestation. We found that the administration of CDP-choline (200 mg/kg body wt) at birth has a moderately beneficial effect on the respiratory frequency, dynamic lung compliance, and expiratory lung...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/0300-9572(80)90005-2

    authors： Lachmann B,Grossmann G,Malmqvist E,Nilsson R,Robertson B

    更新日期：1980-03-01 00:00:00

  • A public access defibrillation programme in non-inpatient hospital areas.

    abstract：INTRODUCTION:Automatic external defibrillators (AED) have proven to be valuable and life saving for out of hospital cardiac arrests. Their use in hospital arrests is less well documented, but they offer the opportunity to improve survival in the hospital setting also. METHODS:The implementation of a public access defi...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2005.09.025

    authors： Friedman FD,Dowler K,Link MS

    更新日期：2006-06-01 00:00:00

  • Pediatric advanced life support re-training by videoconferencing compared to face-to-face instruction: a planned non-inferiority trial.

    abstract：STUDY AIM:Videoconferencing technology may be useful for providing Pediatric Advanced Life Support (PALS) re-training to geographically isolated providers. Yet, it is unclear whether learning outcomes will be similar to those obtained with traditional, face-to-face instruction. This study assess whether PALS re-trainin...

    journal_title：Resuscitation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.resuscitation.2008.05.008

    authors： Weeks DL,Molsberry DM

    更新日期：2008-10-01 00:00:00

  • Should age be included as a component of track and trigger systems used to identify sick adult patients?

    abstract：AIM OF STUDY:Few published "track and trigger systems" used to identify sick adult patients incorporate patient age as a variable. We investigated the relationship between vital signs, patient age and in-hospital mortality and investigated the impact of patient age on the function as predictors of in-hospital mortality...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2008.03.004

    authors： Smith GB,Prytherch DR,Schmidt PE,Featherstone PI,Kellett J,Deane B,Higgins B

    更新日期：2008-08-01 00:00:00

  • Duration of CPR and impact on 30-day survival after ROSC for in-hospital cardiac arrest-A Swedish cohort study.

    abstract：OBJECTIVES:Resuscitation on in-hospital cardiac arrest (IHCA) is estimated to occur in 200,000 hospitalised patients annually in the US. The duration of the resuscitation attempt, measured as minutes of cardiopulmonary resuscitation (CPR), and its impact on survival remains unknown. AIM:Investigate if there is a diffe...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2018.08.017

    authors： Rohlin O,Taeri T,Netzereab S,Ullemark E,Djärv T

    更新日期：2018-11-01 00:00:00

  • Mortality in patients resuscitated from out-of-hospital cardiac arrest based on automated blood cell count and neutrophil lymphocyte ratio at admission.

    abstract：INTRODUCTION:The neutrophil lymphocyte ratio(NLR) is a marker of systemic inflammation. We hypothesized that admission NLR is related to mortality and that epinephrine application during resuscitation influences NLR in patients after successful resuscitation from out of hospital cardiac arrest (OHCA). METHODS:This ret...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2017.05.006

    authors： Weiser C,Schwameis M,Sterz F,Herkner H,Lang IM,Schwarzinger I,Spiel AO

    更新日期：2017-07-01 00:00:00

  • Crystalloid vs. hypertonic crystalloid-colloid solutions for induction of mild therapeutic hypothermia after experimental cardiac arrest.

    abstract：PURPOSE:To compare cerebral and hemodynamic consequences of different volumes of cold acetated Ringer's solution or cold hypertonic saline dextran administered in order to achieve mild hypothermia after cardiac arrest (CA) in a pig model of experimental cardiopulmonary resuscitation (CPR). METHODS:Using an experimenta...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2012.06.024

    authors： Miclescu A,Sharma HS,Wiklund L

    更新日期：2013-02-01 00:00:00

  • Effectiveness of the new 'Mobile AED Map' to find and retrieve an AED: A randomised controlled trial.

    abstract：BACKGROUND:Although early shock with an automated external defibrillator (AED) is one of the several key elements to save out-of-hospital cardiac arrest (OHCA) victims, it is not always easy to find and retrieve a nearby AED in emergency settings. We developed a cell phone web system, the Mobile AED Map, displaying nea...

    journal_title：Resuscitation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.resuscitation.2010.09.466

    authors： Sakai T,Iwami T,Kitamura T,Nishiyama C,Kawamura T,Kajino K,Tanaka H,Marukawa S,Tasaki O,Shiozaki T,Ogura H,Kuwagata Y,Shimazu T

    更新日期：2011-01-01 00:00:00

  • Oximetry-Guided normoxic resuscitation following canine cardiac arrest reduces cerebellar Purkinje neuronal damage.

    abstract：BACKGROUND:Animal studies indicate that maintaining physiologic O2 levels (normoxia) immediately after restoration of spontaneous circulation (ROSC) from cardiac arrest (CA) results in less hippocampal neuronal death compared to animals ventilated with 100% O2. This study tested the hypothesis that beneficial effects o...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2019.04.043

    authors： Lee D,Pearson T,Proctor JL,Rosenthal RE,Fiskum G

    更新日期：2019-07-01 00:00:00

  • A web-based micro-simulation program for self-learning BLS skills and the use of an AED. Can laypeople train themselves without a manikin?

    abstract：AIM:Various methods, including self-instruction, have been used to try to improve the acquisition of basic life support skills. This is a preliminary report of the effectiveness of a web-based self-training program for BLS and the use of an AED. METHODS:Sixteen volunteers completed on-line training in their own time o...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2007.05.014

    authors： de Vries W,Handley AJ

    更新日期：2007-12-01 00:00:00

  • Post-discharge outcomes after resuscitation from out-of-hospital cardiac arrest: A ROC PRIMED substudy.

    abstract：IMPORTANCE:Assessment of morbidity is an important component of evaluating interventions for patients with out-of-hospital cardiac arrest (OHCA). OBJECTIVE:We evaluated among survivors of OHCA cognition, functional status, health-related quality of life and depression as functions of patient and emergency medical serv...

    journal_title：Resuscitation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.resuscitation.2015.05.011

    authors： Nichol G,Guffey D,Stiell IG,Leroux B,Cheskes S,Idris A,Kudenchuk PJ,Macphee RS,Wittwer L,Rittenberger JC,Rea TD,Sheehan K,Rac VE,Raina K,Gorman K,Aufderheide T,Resuscitation Outcomes Consortium Investigators.

    更新日期：2015-08-01 00:00:00

  • Relief of pain in intensive care patients.

    abstract：:Many critically ill patients suffer pain which can produce by itself undesirable effects. Consequently, pain must be carefully prevented, or at least, treated early and effectively. Basal analgesia can be provided by repeated intramuscular administration of narcotics, or rather by continuous intravenous infusion of mo...

    journal_title：Resuscitation

    pub_type： 杂志文章,评审

    doi：10.1016/0300-9572(84)90013-3

    authors： Berré J

    更新日期：1984-03-01 00:00:00

  • Brain enzyme changes as markers of brain damage in rat cardiac arrest model. Effects of corticosteroid therapy.

    abstract：:Apneic asphyxia to cardiac arrest (CA) in rats of 10 min was reversed by cardiopulmonary resuscitation (CPR), and after controlled ventilation and controlled normotension for 20 min, was followed by decapitation and brain freezing, and determination of brain concentrations of cytosolic and lysosomal enzymes. Normal va...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/0300-9572(89)90078-6

    authors： Katz L,Vaagenes P,Safar P,Diven W

    更新日期：1989-02-01 00:00:00

  • Chest-compression-only versus conventional cardiopulmonary resuscitation by bystanders for children with out-of-hospital cardiac arrest: A systematic review and meta-analysis.

    abstract：BACKGROUND:For children with out-of-hospital cardiac arrest, previous observational studies regarding chest-compression-only CPR (CC-CPR) versus conventional CPR yielded inconsistent results. We aimed to summarize the current evidence and compare the outcomes after CC-CPR with those after conventional CPR by bystanders...

    journal_title：Resuscitation

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.resuscitation.2018.10.032

    authors： Zhang X,Zhang W,Wang C,Tao W,Dou Q,Yang Y

    更新日期：2019-01-01 00:00:00

  • A local neighborhood volunteer network improves response times for simulated cardiac arrest.

    abstract：AIM:Each minute is crucial in the treatment of out-of-hospital cardiac arrest (CA). Immediate chest compressions and early defibrillation are keys to good outcomes. We hypothesized that a coordinated effort of alerting trained local neighborhood volunteers (vols) simultaneously with 911 activation of professional EMS p...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2019.09.016

    authors： Kern KB,Colberg TP,Wunder C Jr,Newton C,Slepian MJ

    更新日期：2019-11-01 00:00:00

  • Rapid cardiac ultrasound of inpatients suffering PEA arrest performed by nonexpert sonographers.

    abstract：UNLABELLED:Cardiac arrest presenting as pulseless electrical activity (PEA) currently has a very low survival rate. Many of the conditions underlying PEA (cardiac tamponade, hypovolemia, and pulmonary embolus) are associated with specific cardiac ultrasound findings. The aim of this study was to evaluate a rapid cardia...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2005.04.007

    authors： Niendorff DF,Rassias AJ,Palac R,Beach ML,Costa S,Greenberg M

    更新日期：2005-10-01 00:00:00

  • Systematic review and meta-analysis of hemodynamic-directed feedback during cardiopulmonary resuscitation in cardiac arrest.

    abstract：BACKGROUND/OBJECTIVE:Physiologic monitoring of resuscitative efforts during cardiac arrest is gaining in importance, as it provides a real-time window into the cellular physiology of patients. The aim of this review is to assess the quality of evidence surrounding the use of physiologic monitoring to guide cardiopulmon...

    journal_title：Resuscitation

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.resuscitation.2016.01.025

    authors： Chopra AS,Wong N,Ziegler CP,Morrison LJ

    更新日期：2016-04-01 00:00:00

  • Clinical course and long-term outcome following venoarterial extracorporeal life support-facilitated interhospital transfer of patients with circulatory failure.

    abstract：BACKGROUND:Interhospital transfer of patients experiencing circulatory failure and shock has a significant risk of cardiovascular deterioration and death. Extracorporeal life support (ECLS) is a rescue tool for hemodynamic stabilization that makes patient transportation much safer. METHODS:Demographic data, clinical c...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2015.05.021

    authors： Schopka S,Philipp A,Hilker M,Müller T,Zimmermann M,Arlt M,Rupprecht L,Schmid C,Lunz D

    更新日期：2015-08-01 00:00:00

  • Impact of the direct transfer to percutaneous coronary intervention-capable hospitals on survival to hospital discharge for patients with out-of-hospital cardiac arrest.

    abstract：AIMS:Patients suffering from out-of-hospital cardiac arrest (OHCA) are frequently transported to the closest hospital. Percutaneous coronary intervention (PCI) is often indicated following OHCA. This study's primary objective was to determine the association between being transported to a PCI-capable hospital and survi...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2018.01.048

    authors： Cournoyer A,Notebaert É,de Montigny L,Ross D,Cossette S,Londei-Leduc L,Iseppon M,Lamarche Y,Sokoloff C,Potter BJ,Vadeboncoeur A,Larose D,Morris J,Daoust R,Chauny JM,Piette É,Paquet J,Cavayas YA,de Champlain F,Segal

    更新日期：2018-04-01 00:00:00

  • Therapeutic hypothermia after cardiac arrest - cerebral perfusion and metabolism during upper and lower threshold normocapnia.

    abstract：BACKGROUND:During cardiac arrest and after successful resuscitation a continuum of ischaemia-reperfusion injury develops. Mild hypothermia exerts protective effects in the postresuscitation phase but also alters CO₂ production and solubility, which may lead to deleterious effects if overlooked when adjusting the ventil...

    journal_title：Resuscitation

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.resuscitation.2011.04.022

    authors： Pynnönen L,Falkenbach P,Kämäräinen A,Lönnrot K,Yli-Hankala A,Tenhunen J

    更新日期：2011-09-01 00:00:00

  • Heart rate variability predicts short-term outcome for successfully resuscitated patients with out-of-hospital cardiac arrest.

    abstract：OBJECTIVE:To assess the possibility of heart rate variability (HRV) measures as predictors of 24-h mortality in successfully resuscitated patients with out-of-hospital cardiac arrest (OHCA). METHODS:This prospective cohort study was conducted at a 40-bed emergency department (ED) of a university-affiliated medical cen...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2009.06.020

    authors： Chen WL,Tsai TH,Huang CC,Chen JH,Kuo CD

    更新日期：2009-10-01 00:00:00

  • Comparison of two emergency response systems and their effect on survival from out of hospital cardiac arrest.

    abstract：:The pre-hospital care provided by emergency response systems will have an effect on the outcome of patients who have sustained an out of hospital cardiac arrest. This study compares the results of resuscitation in two centres, one in the UK (Edinburgh) and the other in the USA (Milwaukee), and examines the demographic...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/s0300-9572(97)00072-5

    authors： Mitchell RG,Brady W,Guly UM,Pirrallo RG,Robertson CE

    更新日期：1997-11-01 00:00:00

  • Performance of coronary angiography and intervention after out of hospital cardiac arrest.

    abstract：AIMS:Out of Hospital Cardiac Arrest (OHCA) is frequently attributed to coronary artery disease, thus guidelines recommend coronary angiography (CAG) for survivors of OHCA. However, the real-world application of these guidelines is unknown, and we sought to evaluate CAG practices in the contemporary OHCA population. ME...

    journal_title：Resuscitation

    pub_type： 杂志文章

    doi：10.1016/j.resuscitation.2018.10.007

    authors： Kearney KE,Maynard C,Smith B,Rea TD,Beatty A,McCabe JM

    更新日期：2018-12-01 00:00:00