Actin and flagellin may have an N-terminal relationship.

abstract：:Computational analysis of the hypothetical open reading frame MJ0236 from Methanococcus jannaschii reveals its membership to a family of bacterial and eukaryotic proteins, predicted to be the HMP-P kinases involved in thiamin biosyntheis (ThiD). The eukaryotic members of this family contain a C-terminal extension simi...

journal_title：Journal of molecular evolution

authors： Ouzounis CA,Kyrpides NC

更新日期：1997-12-01 00:00:00

abstract：:Members of the serpin (serine protease inhibitor) superfamily of genes are well represented in both human and murine genomes. In many cases it is possible to identify a definite ortholog on the basis of sequence similarity and by examining the surrounding genes at syntenic loci. We have recently examined the murine se...

journal_title：Journal of molecular evolution

authors： Horvath AJ,Forsyth SL,Coughlin PB

更新日期：2004-10-01 00:00:00

abstract：:The mammalian defensin molecule is a short, highly cationic peptide cytotoxic to both microbial and mammalian cells which is cleaved from a precursor including a signal peptide and a highly anionic propiece. A phylogenetic analysis of 28 complete sequences from five mammalian species (mouse, rat, guinea pig, rabbit, a...

journal_title：Journal of molecular evolution

authors： Hughes AL,Yeager M

更新日期：1997-06-01 00:00:00

abstract：:LINE-1 (L1) elements constitute the major family of retrotransposons in mammalian genomes. Here we report the first investigation of L1 evolution in New World monkeys (NWM). Two regions of the second open-reading frame were analyzed by two methods in three NWM species, the squirrel monkey (Saimiri sciureus), the tamar...

journal_title：Journal of molecular evolution

authors： Boissinot S,Roos C,Furano AV

更新日期：2004-01-01 00:00:00

abstract：:The genome organization of the Hardness locus in the tribe Triticeae constitutes an excellent model for studying the mechanisms of evolution that played a role in the preservation and potential functional innovations of duplicate genes. Here we applied the nonsynonymous-synonymous rate ratio (d ( N )/d ( S ) or omega)...

journal_title：Journal of molecular evolution

authors： Massa AN,Morris CF

更新日期：2006-10-01 00:00:00

abstract：:We have previously shown that several multicopy gene families within the major histocompatibility complex (MHC) arose from a process of segmental duplication. It has also been observed that retroelements play a role in generating diversity within these duplicated segments. The objective of this study was to compare th...

journal_title：Journal of molecular evolution

authors： Freitas EM,Gaudieri S,Zhang WJ,Kulski JK,van Bockxmeer FM,Christiansen FT,Dawkins RL

更新日期：2000-04-01 00:00:00

abstract：:A major goal of evolutionary biology is to understand how beneficial mutations translate into increased fitness. Here, we study beneficial mutations that arise in experimental populations of yeast evolved in glucose-rich media. We find that fitness increases are caused by enhanced maximum growth rate (R) that come at ...

journal_title：Journal of molecular evolution

authors： Sezmis AL,Malerba ME,Marshall DJ,McDonald MJ

更新日期：2018-02-01 00:00:00

abstract：:The specificity of interaction of amino acids with triplets in the acceptor helix stem of tRNA was investigated by means of a statistical analysis of 1400 tRNA sequences. The imprint of a prototypic genetic code at position 3-5 of the acceptor helix was detected, but only for those major amino acids, glycine, alanine,...

journal_title：Journal of molecular evolution

authors： Möller W,Janssen GM

更新日期：1992-06-01 00:00:00

abstract：:In this work detailed statistics on ancestral gene duplication and gene conservation in completely sequenced cellular genomes are presented. Analysis of open reading frame (ORF) products having simultaneous matches in several distinct organisms showed a significant correlation between duplication and conservation. Sys...

journal_title：Journal of molecular evolution

authors： Tekaia F,Dujon B

更新日期：1999-11-01 00:00:00

abstract：:Nuclear DNA contents were estimated by microdensitometry in five species of Akodon rodents: Arodon molinae, A. dolores, A. mollis, A. azarae, Bolomys obscurus) and in three chromosomal varieties of A. molinae (2n = 42; 2n = 43, 2n = 22). The data obtained showed that the species with the highest DNA content was B. obs...

journal_title：Journal of molecular evolution

authors： Bianchi NO,Redi C,Garagna C,Capanna E,Manfredi-Romanini MG

更新日期：1983-01-01 00:00:00

abstract：:Intron-encoded U17 RNA is a member of the H/ACA box class of small nucleolar RNAs (snoRNAs) involved in ribosomal RNA (rRNA) maturation. U17 snoRNA shows typical characteristics of guide RNAs, which specify sites of pseudouridylation on the precursor rRNA (pre-rRNA). However, in spite of the presence of H and ACA boxe...

journal_title：Journal of molecular evolution

authors： Cervelli M,Cecconi F,Giorgi M,Annesi F,Oliverio M,Mariottini P

更新日期：2002-02-01 00:00:00

abstract：:We describe the complete mitochondrial genome of the house centipede Scutigera coleoptrata. Its gene order is unique among characterized arthropod mitochondrial genomes. Comparison to the gene order in the horseshoe crab mtDNA implies 10 or more translocations. By extending comparisons to 30 arthropod mitochondrial ge...

journal_title：Journal of molecular evolution

authors： Negrisolo E,Minelli A,Valle G

更新日期：2004-04-01 00:00:00

abstract：:Using all currently predicted coding regions in the honeybee genome, a novel form of synonymous codon bias is presented that affects the usage of particular codons dependent on the surrounding nucleotides in the coding region. Nucleotides at the third codon site are correlated, dependent on their weak (adenine [A] or ...

journal_title：Journal of molecular evolution

authors： Cutler RW,Chantawannakul P

更新日期：2007-06-01 00:00:00

abstract：:Proteins are commonly used as molecular targets against pathogens such as viruses and bacteria. However, pathogens can evolve rapidly permitting their populations to increase in protein diversity over time and thus escape to the activity of a molecular therapy. Subsequently, in order to design more durable and robust ...

journal_title：Journal of molecular evolution

authors： Arenas M

更新日期：2020-08-01 00:00:00

abstract：:The early evolution of life is a period with many important events with a lot of big and open questions. One of them is the evolution of metabolic pathways, which means the origin and assembly of enzymes that act together. The retrograde hypothesis was the first attempt to explain the origin and evolutionary history o...

journal_title：Journal of molecular evolution

authors： Becerra A

更新日期：2021-01-28 00:00:00

abstract：:Bacterial lipoproteins, characterized by the N-terminal N-acyl S-diacylglyceryl Cysteine, are key membrane proteins in bacterial homeostasis. It is generally thought that during the modification lipoprotein precursors are translocated via the Sec-machinery in an unfolded state. The recent discovery of twin-arginine tr...

journal_title：Journal of molecular evolution

authors： Shruthi H,Babu MM,Sankaran K

更新日期：2010-04-01 00:00:00

abstract：:The recent availability of genome sequences of four different Fusarium species offers the opportunity to perform extensive comparative analyses, in particular of repeated sequences. In a recent work, the overall content of such sequences in the genomes of three phylogenetically related Fusarium species, F. graminearum...

journal_title：Journal of molecular evolution

authors： Dufresne M,Lespinet O,Daboussi MJ,Hua-Van A

更新日期：2011-10-01 00:00:00

abstract：:The sequences of the adenylate kinase gene (adk) and the RecA gene (recA) were determined from the same isolates of Neisseria gonorrhoeae, N. meningitidis, N. lactamica, N. polysaccharea, N. cinerea, N. mucosa, N. pharyngis var. flava, N. flavescens, and N. animalis. The patterns of sequence divergence observed at adk...

journal_title：Journal of molecular evolution

authors： Feil E,Zhou J,Maynard Smith J,Spratt BG

更新日期：1996-12-01 00:00:00

abstract：:Evidence from a number of studies indicates that protein folding is dictated not only by factors stabilizing the native state, but also by potentially independent factors that create folding pathways. How natural selection might cope simultaneously with two independent factors was addressed in this study within the fr...

journal_title：Journal of molecular evolution

authors： Lee SY,Parker W

更新日期：2011-10-01 00:00:00

abstract：:In this paper we present a new method for detecting block duplications in a genome. It is more stringent than previous ones in that it requires a more rigorous definition of paralogous genes and that it requires the paralogous proteins on the two blocks to be contiguous. In addition, it provides three criterion choice...

journal_title：Journal of molecular evolution

authors： Cavalcanti AR,Ferreira R,Gu Z,Li WH

更新日期：2003-01-01 00:00:00

abstract：:Nucleotide polymorphisms in two North American balsam poplars (Populus trichocarpa Torr. & Gray and P. balsamifera L.; section Tacamahaca), and one Eurasian aspen (P. tremula L.; section Populus) were compared using nine loci involved in defense, stress response, photoperiodism, freezing tolerance, and housekeeping. N...

journal_title：Journal of molecular evolution

authors： Ismail M,Soolanayakanahally RY,Ingvarsson PK,Guy RD,Jansson S,Silim SN,El-Kassaby YA

更新日期：2012-06-01 00:00:00

abstract：:Gene duplication by retrotransposition duplicates only the coding and untranslated regions of a gene and, thus, biases retroduplicated genes toward having different expression patterns from their parental genes. As such, genes duplicated by retrotransposition are more likely to develop novel expression domains. To exp...

journal_title：Journal of molecular evolution

authors： Penney J,Bossé J,Clark DV

更新日期：2008-05-01 00:00:00

abstract：:Scorpion venom toxins were systematically classified according to amino acid composition, insertion/deletion events and sequence. The significance of each comparison method and its outcome is discussed in relation to known immunological and structural properties. A general classification of the toxins is proposed that...

journal_title：Journal of molecular evolution

authors： Dufton MJ,Rochat H

更新日期：1984-01-01 00:00:00

abstract：:We provide here evidence for a conserved regulatory element for transcription of the β-family globin genes based on a comparative study of 32 genes from 16 mammals. The element is characterized by the appearance of AA or TT dinucleotides in the A + T-rich region located 200-400 bp upstream of the cap sites. G-tracts 3...

journal_title：Journal of molecular evolution

authors： Kiyama R,Wada-Kiyama Y

更新日期：2011-10-01 00:00:00

abstract：:We examined the nucleotide and amino acid sequence variation of the cytochrome c oxidase subunit II (COII) gene from 25 primates (4 hominoids, 8 Old World monkeys, 2 New World monkeys, 2 tarsiers, 7 lemuriforms, 2 lorisiforms). Marginal support was found for three phylogenetic conclusions: (1) sister-group relationshi...

journal_title：Journal of molecular evolution

authors： Adkins RM,Honeycutt RL

更新日期：1994-03-01 00:00:00

abstract：:The incomplete correlation between the organismal complexities and the number of genes among eukaryotic organisms can be partially explained by multiple protein products of a gene created by alternative splicing. One type of alternative splicing involves alternative selection of mutually exclusive exons and creates pr...

journal_title：Journal of molecular evolution

authors： Chen YC,Lin WH,Tzeng DW,Chow WY

更新日期：2006-02-01 00:00:00

abstract：:We have studied the metal-ion catalysis of a number of reactions of the isomers of ImpGpG on a poly(C) template. In the absence of a catalytic metal ion, oligomers at least up to (pG)20 are obtained from the ImpGpG isomers in a 1-methylimidazole buffer. The Pb2+ ion improves the yield of longer oligomers and changes s...

journal_title：Journal of molecular evolution

authors： Lohrmann R,Bridson PK,Orgel LE

更新日期：1981-01-01 00:00:00

abstract：:Two protein-coding regions (cytochrome b, ATPase 8, and part of ATPase 6) from mitochondrial DNA of Cottus kessleri, Cottocomephorus grewingki, and Cottocomephorus inermis--Baikalian endemic sculpins--were amplified via polymerase chain reaction, and sequenced. Two novel primers--L8352 (5'-TAAAGATTGGTGAC TCCCAACCACC) ...

journal_title：Journal of molecular evolution

authors： Grachev MA,Slobodyanyuk SJa,Kholodilov NG,Fyodorov SP,Belikov SI,Sherbakov DYu,Sideleva VG,Zubin AA,Kharchenko VV

更新日期：1992-01-01 00:00:00

abstract：:Examination of the mitochondrial small subunit ribosomal RNA (rns) gene of five species of the fungal genus Leptographium revealed that the gene has been invaded at least once at position 952 by a group II intron encoding a LAGLIDADG homing endonuclease gene. Phylogenetic analyses of the intron and homing endonuclease...

journal_title：Journal of molecular evolution

authors： Mullineux ST,Willows K,Hausner G

更新日期：2011-06-01 00:00:00

abstract：:The gene content of a mitochondrial (mt) genome, i.e., 37 genes and a large noncoding region (LNR), is usually conserved in Metazoa. The arrangement of these genes and the LNR is generally conserved at low taxonomic levels but varies substantially at high levels. We report here a variation in mt gene content and gene ...

journal_title：Journal of molecular evolution

authors： Shao R,Barker SC,Mitani H,Takahashi M,Fukunaga M

更新日期：2006-08-01 00:00:00