Abstract:
:A rapid, semiautomated radioimmunoassay system for detection of morphine, barbiturates, and amphetamines is described. The assays are applicable to large drug abuse screening programs. The heart of the system is the automatic pipetting station which can accomplish 600 pipetting operations per hour. The method uses 15 to 30 mul or urine for the morphine and barbiturate assay and 100 mul for the amphetamine and combined morphine/barbiturate assays. A number of other drugs were tested for interference with the assays and the results are discussed.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Sulkowski TS,Lathrop GD,Merritt JH,Landez JH,Noe ERkeywords:
subject
Has Abstractpub_date
1975-07-01 00:00:00pages
524-36issue
3eissn
0022-1198issn
1556-4029journal_volume
20pub_type
杂志文章abstract::Two hundred eighty-seven deaths directly related to narcotic abuse occurred in the District of columbia between July 1971 and December 1979. Factors contributing to death in some cases included lack of opiate tolerance as well as the conjoint abuse of ethanol. Free morphine was identified more often in the blood of vi...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
abstract::Many epidemiological, clinical, and autopsy studies have demonstrated that the risk of sudden coronary death (SCD) is linked to the severity of coronary atherosclerotic lesions and to their thrombotic potential. However it remains unknown why some individuals manifest no clinical evidence of coronary disease until the...
journal_title:Journal of forensic sciences
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更新日期:1993-09-01 00:00:00
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journal_title:Journal of forensic sciences
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更新日期:2005-07-01 00:00:00
abstract::The fingernails of Mary Sullivan, the last victim of the Boston Strangler, were examined to determine if any genetic information about the murderer could be obtained. The nails were extremely friable necessitating the development of new techniques for isolating and purifying DNA. DNA yields from nails were optimized b...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
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更新日期:2003-03-01 00:00:00
abstract::Drowning as a method of suicide is known to occur, but has primarily been described in environments with readily available access to water, such as coastal regions. In this study, we describe and analyze a series of suicidal drownings occurring in a noncoastal area of Texas. Between 1977 and 1996, 52 cases of suicidal...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
abstract::DNA evidence holds an important position in criminal investigations and proceedings. The polymerase chain reaction (PCR) is often utilized to amplify polymorphic regions of DNA which are subsequently typed to produce distinct genotypes. The sensitivity of PCR-based techniques provides a major advantage over other DNA ...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract::A fatality in a teenager from the recreational intranasal abuse of methylphenidate (Ritalin) is reported. The prescribed use of methylphenidate (Ritalin) in the treatment of attention deficit and/or hyperactivity disorder is widespread. The intranasal abuse of methylphenidate (Ritalin) among teenagers is becoming incr...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::A case of multiple animal bite wounds is presented along with the techniques used to apprehend the culprits. The victim was a 13 month-old black female who had in excess of 80 puncture wounds. Initially the wounds were thought to be caused by a mechanical instrument but, after an autopsy, were determined to be caused ...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract::Computer methods have been developed for mathematically interpreting mixed and low-template DNA. The genotype modeling approach computationally separates out the contributors to a mixture, with uncertainty represented through probability. Comparison of inferred genotypes calculates a likelihood ratio (LR), which measu...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12788
更新日期:2015-07-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2011.01880.x
更新日期:2011-09-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.13870
更新日期:2019-03-01 00:00:00
abstract::When insect evidence is obtained during autopsy, forensic entomologists make decisions regarding the effects of low-temperature (-1 degrees C to 4 degrees C) storage of the body and associated insects when estimating the post-mortem interval (PMI). To determine the effects of storage in a morgue cooler on the temperat...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2007.00385.x
更新日期:2007-03-01 00:00:00
abstract::Reproducibility of quantitative PCR results is dependent on the generation of consistent calibration curves via accurate volume transfers and instrument performance. A review of 14 standard curves, using two different QuantDuo® standard DNA lots, showed variability of cycle threshold values between assays were larger ...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2010.01460.x
更新日期:2010-09-01 00:00:00
abstract::This study extends previous work on the sorption of explosives to the hair matrix. Specifically, we have studied the interaction of 2,4,6-trinitrotoluene (TNT) and triacetone triperoxide (TATP) as a function of chemical pretreatment with acetonitrile, neutral and alkaline hydrogen peroxide, methanolic KOH and potassiu...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2011.02020.x
更新日期:2012-05-01 00:00:00
abstract::Intercostal and age differences in the sternal rib end morphology of documented female skeletons from Spitalfields and St. Bride's are examined. The morphology was captured using three-dimensional morphometrics and the statistical analyses employed included parametric and nonparametric MANOVA, discriminant analysis, a...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12047
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1988-03-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2006.00336.x
更新日期:2007-01-01 00:00:00
abstract::Using GC/MS in scanning mode as a screening and definitive identification methodology for substance abuse testing, 4500 urine samples have been analyzed. The accuracy and sensitivity of this method was evaluated by the results of 92 proficiency sample analyses, reanalyses by TLC screening with GC confirmation of 125 s...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::During postmortem examination of the dental arches of carbonized victims, dental restorative materials may be found. The aim of this study was to evaluate the effect of heat source action on the color stability of composite resin (CR) and glass ionomer cement (GIC) restorations, to discriminate between them and compar...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.13292
更新日期:2017-03-01 00:00:00
abstract::Collection of DNA for genetic profiling is a powerful means for the identification of individuals responsible for crimes and terrorist acts. Biologic hazards, such as bacteria, endospores, toxins, and viruses, could contaminate sites of terrorist activities and thus could be present in samples collected for profiling....
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12561
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abstract::A method to use ionizing radiation to inactivate HIV (Human Immunodeficiency Virus) in human body fluids was studied in an effort to reduce the risk of accidental infection to forensic science laboratory workers. Experiments conducted indicate that an X-ray absorbed dose of 25 krad was required to completely inactivat...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
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更新日期:2012-05-01 00:00:00
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journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract::As issues of professional standards and error rates continue to be addressed in the courts, forensic anthropologists should be proactive by developing and adhering to professional standards of best practice. There has been recent increased awareness and interest in critically assessing some of the techniques used by f...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2009.01176.x
更新日期:2009-11-01 00:00:00
abstract::Additional studies were performed with respect to examining the lower limits at which canines can reliably detect products commonly used as accelerants and distinguish them from pyrolysis products or background hydrocarbons. As part of a testing exercise performed in conjunction with a national conference of the Canin...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::We describe a massive fatal posterior myocardial infarct resulting from compression of the right coronary artery by a Teflon pledget granuloma in a patient who had undergone aortic valve replacement six months before death. Other iatrogenic causes of coronary artery occlusion or compression are discussed in this paper...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract::Borate-containing compounds were formerly used as topical antiseptics and were components of many medicinal preparations including skin powders and ointments used for the treatment of burns and diaper rash. These compounds were also used as irrigants for body cavities, including the pleural, vaginal, and rectal caviti...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2007.00420.x
更新日期:2007-05-01 00:00:00
abstract::Bloodhounds are used to trail fleeing felons and missing persons. In order to start a trail, the dog must be presented with a person's scent. There are many hypotheses on what a bloodhound smells while trailing. The present study attempts to identify whether human scent is genetic, and if it is influenced by one's env...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2006.00231.x
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