Cloning, tissue expression pattern and genomic organization of latexin, a human homologue of rat carboxypeptidase A inhibitor.

abstract：:45S ribosomal precursor RNA and large heterogeneous RNA molecules (greater than 45S) extracted from human leukemic cells were incubated in vitro with purified RNase III, which specifically attacks double-helical RNA regions. About 50% of the ribosomal precursor was cleaved into two major fragments sedimenting at 28S a...

journal_title：Molecular biology reports

authors： Torelli UL,Ferrari S,Torelli GM,Cadossi R,Ferrari S,Montagnani G,Narni F

更新日期：1977-12-01 00:00:00

abstract：:Our previous studies have shown that miR-125b-5p was highly expressed and significantly upregulated during abdominal fat deposition in chickens. However, the role of miR-125b in the regulation of adipogenesis is not clear in chickens. Therefore, we evaluated the effects of miR-125b-5p on preadipocyte proliferation and...

journal_title：Molecular biology reports

authors： Li G,Chen Y,Jin W,Zhai B,Li Y,Sun G,Li H,Kang X,Tian Y

更新日期：2021-01-04 00:00:00

abstract：:Schistosomiasis, a disease caused by helminth parasites of genus Schistosoma. Its treatment intensively depends on single drug, praziquantel which increases the risk of development of drug-resistant parasite. Inhibitors of human HDAC are profoundly reported as novel anti-cancer drugs and used as new anit-parasitic age...

journal_title：Molecular biology reports

authors： Singh R,Pandey PN

更新日期：2015-03-01 00:00:00

abstract：:Intrinsic bent DNA sites were identified in the 4289 bp segment encompassing the replication zone which directs DNA amplification and transcription of the C3-22 gene of Rhynchosciara americana. Restriction fragments showed reduced electrophoretic mobility in polyacrylamide gels. The 2D modeling of the 3D DNA path and ...

journal_title：Molecular biology reports

authors： Fiorini A,de Gouveia FS,de Soares MA,Stocker AJ,Ciferri RR,Fernandez MA

更新日期：2006-03-01 00:00:00

abstract：:The glutathione S-transferase (GST) family of enzymes is known to play a pivotal role in phase II of biotransformation of xenobiotics, environmental carcinogens and pharmacological drugs. The objective of the present study was to investigate the role of GSTM1 and GSTT1 null genotypes as risk factors for chronic obstru...

journal_title：Molecular biology reports

authors： Thakur H,Gupta L,Sobti RC,Janmeja AK,Seth A,Singh SK

更新日期：2011-03-01 00:00:00

abstract：:Serotonin receptor (5-HT) is a biogenic amine acting as a neurotransmitter and neuromodulator that mediates various aspects of reproduction and gametogenesis. The full-length nucleotide sequence of Haliotis discus hannai encodes a protein of 417 amino acids with a predicted molecular mass of 46.54 kDa and isoelectric ...

journal_title：Molecular biology reports

authors： Sharker MR,Sukhan ZP,Kim SC,Lee WK,Kho KH

更新日期：2020-01-01 00:00:00

abstract：:Membrane-bound ribosomes were isolated from a post-mitochondrial supernatant fraction of mouse liver homogenate by sedimentation in a sucrose density gradient, Loose ribosomes were released from the membrane fragments with 0.5 M KCl, while tight bound ribosomes were not released. After purification of the loose and ti...

journal_title：Molecular biology reports

authors： Hoffman WL,Dowben RM

更新日期：1980-07-31 00:00:00

abstract：:Nerve growth factor (NGF) is required for the differentiation and maintenance of sympathetic and sensory neurons. In the present study, the recombinant expression of human nerve growth factor beta (hNGF-β) gene in rabbit bone marrow mesenchymal stem cells (rMSCs) was undertaken. Recombinant vector containing hNGF-β wa...

journal_title：Molecular biology reports

authors： Fan BS,Lou JY

更新日期：2010-12-01 00:00:00

abstract：:The aim of this work was to study β-defensin 1 (SBD1) and β-defensin 2 (SBD2) genes in Valle del Belice dairy sheep in order to identify polymorphisms that can be utilized as markers of the analyzed genes, and search for the functional effects and roles of the identified polymorphisms (variation of the amino acid sequ...

journal_title：Molecular biology reports

authors： Monteleone G,Calascibetta D,Scaturro M,Galluzzo P,Palmeri M,Riggio V,Portolano B

更新日期：2011-11-01 00:00:00

abstract：:Consistent with its precloning characterization from the cellulolytic Bacillus sp., beta-1,4-endoglucanase purified from the recombinant E. coli exhibited maximum activity at 60 degrees C and pH 7.0. It was highly specific for CMC hydrolysis, with stability up to 70 degrees C and over a pH range of 6.0-8.0. The K(m) a...

journal_title：Molecular biology reports

authors： Afzal S,Saleem M,Yasmin R,Naz M,Imran M

更新日期：2010-04-01 00:00:00

abstract：:The mRNA differential display technique was performed to investigate the differences of gene expression in the longissimus muscle tissues from Meishan and Large White pigs. One novel mRNA that was differentially expressed was identified through semi-quantitative RT-PCR and the cDNA complete sequence was then obtained ...

journal_title：Molecular biology reports

authors： Liu GY,Xiong YZ

更新日期：2009-07-01 00:00:00

abstract：:The Great-billed Seed-finch, Sporophila maximiliani, is a threatened neotropical bird that has declined mainly due to illegal trapping, with very few records in the wild in the last two decades. Despite the existence of a considerable captive population that could be used for reintroductions into the wild, many indivi...

journal_title：Molecular biology reports

authors： Medolago CAB,Costa MC,Ubaid FK,Glenn TC,Silveira LF,Francisco MR

更新日期：2018-12-01 00:00:00

abstract：:Altered expression and methylation pattern of tumor suppressor and DNA repair genes, in particular involved in mismatch repair (MMR) pathway, frequently occur in primary colorectal (CRC) tumors. However, little is known about (epi)genetic changes of these genes in precancerous and early stages of CRC. The aim of this ...

journal_title：Molecular biology reports

authors： Polakova Vymetalkova V,Vannucci L,Korenkova V,Prochazka P,Slyskova J,Vodickova L,Rusnakova V,Bielik L,Burocziova M,Rossmann P,Vodicka P

更新日期：2013-10-01 00:00:00

abstract：:In this study we are presenting the development of technetium-99m (99mTc) labeled ibuprofen for the imaging of aseptic inflammation. 99mTc-Ibuprofen complex was developed by optimizing the radiolabeling conditions such as reaction time, ligand and reducing agent concentration, pH, reaction time and temperature. Follow...

journal_title：Molecular biology reports

authors： Khan NU,Naqvi SAR,Sohail H,Roohi S,Jamal MA

更新日期：2019-06-01 00:00:00

abstract：:Biochemical networks comprise many diverse components and interactions between them. It has intracellular signaling, metabolic and gene regulatory pathways which are highly integrated and whose responses are elicited by extracellular actions. Previous modeling techniques mostly consider each pathway independently with...

journal_title：Molecular biology reports

authors： Tomar N,Choudhury O,Chakrabarty A,De RK

更新日期：2013-02-01 00:00:00

abstract：:Based on the internal transcribed spacer and inter-simple sequence repeats (ISSR), the phylogenetic relationship and genetic diversity of Metarhizium spp., pathogens found in Chinese burrower bugs, Schiodtella formosana, were analyzed. The results showed that the causative agents of the epizootic green muscardine dise...

journal_title：Molecular biology reports

authors： Luan F,Zhang S,Wang B,Huang B,Li Z

更新日期：2013-01-01 00:00:00

abstract：:The new transcriptomes provided comprehensive sequence profiling data of transcriptomic variation during vernalization in Lily Asiatic Hybrids 'Tiny ghost'. A number of 52,277,184 sequencing raw reads totaling 5.11 Gbp of the chilling treatment (4 °C) sample and 39,466,176 sequencing raw reads totaling 3.85 Gbp of roo...

journal_title：Molecular biology reports

authors： Huang J,Liu X,Wang J,Lü Y

更新日期：2014-06-01 00:00:00

abstract：:A copper(II) complex containing aspartame (APM) as ligand, Cu(APM)2Cl2·2H2O, was synthesized and characterized. In vitro binding interaction of this complex with human serum albumin (HSA) was studied at physiological pH. Binding studies of this complex with HSA are useful for understanding the Cu(APM)2Cl2·2H2O-HSA int...

journal_title：Molecular biology reports

authors： Shahabadi N,Khodaei MM,Kashanian S,Kheirdoosh F,Filli SM

更新日期：2014-05-01 00:00:00

abstract：:Bacterial leaf streak (BLS) caused by Xanthomonas oryzae pv. oryzicola (Xoc) is an important disease of rice, which is responsible for the economic losses worldwide. Functional investigation of differentially expressed protein genes (DEPGs) from rice (Oryza sativa L.) upon Xoc infection provides insight into the molec...

journal_title：Molecular biology reports

authors： Guo L,Guo C,Li M,Wang W,Luo C,Zhang Y,Chen L

更新日期：2014-01-01 00:00:00

abstract：:Overexpression of domains of a human protein using recombinant DNA technology has been challenging because individual domains intend to accumulate as non-soluble aggregate when expressed separately. Studies on identifying right sequences for a domain to be able to fold independently may help understand the folding pat...

journal_title：Molecular biology reports

authors： Tiwary M,Agarwal N,Dinda A,Yadav SC

更新日期：2016-05-01 00:00:00

abstract：:The aim of this study was to characterise the effects of ischemic preconditioning (IP) on heart function parameters (ΔST and ΔT), activities of serum creatine kinase (CK), lactate dehydrogenase (LDH), and levels of serum nitric oxide (NO), malondialdehyde (MDA), and myocardium Caspase-3 mRNA, SOCS-1, SOCS-3, tumor nec...

journal_title：Molecular biology reports

authors： Ma J,Qiao Z,Xu B

更新日期：2013-10-01 00:00:00

abstract：:Human Papillomavirus infection is considered as the main etiological factor of cervical cancer (ICC), although, the role of host genetic factors in ICC susceptibility has been increasing. Immunological response is crucial for the prevention of viral associated diseases. Interleukin 1 receptor antagonist (IL-1RN) is co...

journal_title：Molecular biology reports

authors： Sousa H,Santos AM,Catarino R,Pinto D,Moutinho J,Canedo P,Machado JC,Medeiros R

更新日期：2012-12-01 00:00:00

abstract：:We report here a cDNA and its deduced amino acid sequence encoding a cathepsin D-like, aspartic protease from Chlamys farreri (denoted as CfCD) by expressed sequence tag and rapid amplification of cDNA ends techniques. The cDNA of CfCD consisted of 1,810 nucleotides with a canonical polyadenylation signal sequence AAT...

journal_title：Molecular biology reports

authors： Li C,Zhang H,Li L,Song L

更新日期：2010-03-01 00:00:00

abstract：:We utilized Percoll density gradient centrifugation to isolate and fractionate chloroplasts of Korean winter wheat cultivar cv. Kumgang (Triticum aestivum L.). The resulting protein fractions were separated by one dimensional polyacrylamide gel electrophoresis (1D-PAGE) coupled with LTQ-FTICR mass spectrometry. This e...

journal_title：Molecular biology reports

authors： Kamal AH,Cho K,Komatsu S,Uozumi N,Choi JS,Woo SH

更新日期：2012-05-01 00:00:00

abstract：:The binding characteristics of the interaction between 3-(2-cyanoethyl) cytosine (CECT) and human serum albumin (HSA) were investigated using fluorescence, UV absorption spectroscopic and molecular modeling techniques under simulative physiological conditions. The intrinsic fluorescence intensity of HSA was decreased ...

journal_title：Molecular biology reports

authors： Cui FL,Hui GQ,Huo RN,Qu GR

更新日期：2012-11-01 00:00:00

abstract：:The disturbed immune homeostasis is involved in the pathogenesis of an array of autoimmune diseases like rheumatoid arthritis (RA). The adenosine monophosphate-activated protein kinase (AMPK) with a pivotal role in immunometabolism process, also plays a regulatory function in the immune system. This study aims to eval...

journal_title：Molecular biology reports

authors： Samimi Z,Kardideh B,Zafari P,Bahrehmand F,Roghani SA,Taghadosi M

更新日期：2019-12-01 00:00:00

abstract：:The modified base queuine is a nutrient factor for lower and higher eukaryotes except yeast. It is synthesized in eubacteria and inserted into the wobble position of specific tRNAs (tRNA(GUN)) in exchange of guanine at position 34. The tRNAs of Q family are completely modified in terminally differentiated somatic cell...

journal_title：Molecular biology reports

authors： Pathak C,Vinayak M

更新日期：2005-09-01 00:00:00

abstract：:The melanocortin-4 receptor (MC4R) plays an important role in weight and energy homeostasis and it is associated with lower risk to develop obesity and lower body mass index. The contribution of MC4R mutation to obesity in Vojvodina (Northern Province of Serbia), known as a region with the largest number of overweight...

journal_title：Molecular biology reports

authors： Stokić E,Djan M,Vapa Lj,Djan I,Plećas A,Srdić B

更新日期：2010-01-01 00:00:00

abstract：:Transcription factor RBP-J-mediated Notch signaling has been implicated in several inherited cardiovascular diseases including aortic valve diseases (AVD). But whether Notch signal plays a role in AVD in adults has been unclear. This study aims to test whether the deletion of RBP-J in adult mice would lead to AVD and ...

journal_title：Molecular biology reports

authors： Li Z,Feng L,Wang CM,Zheng QJ,Zhao BJ,Yi W,Zhang JZ,Wang YM,Guo HT,Yi DH,Han H

更新日期：2012-04-01 00:00:00

abstract：:Proteasomes (prosomes) are large multiprotein complexes. They are involved in protein degradation of ubiquitin-conjugated proteins and in the generation of MHC class I peptides. We gave further evidence that they interfere with in vitro protein synthesis. Proteasomes inhibit the translation of Tobacco mosaic virus RNA...

journal_title：Molecular biology reports

authors： Homma S,Horsch A,Pouch MN,Petit F,Briand Y,Schmid HP

更新日期：1994-01-01 00:00:00