Abstract:
:Anaplastic gangliogliomas with an oligodendroglial component are exceedingly rare tumors of uncertain growth potential. We report a 17-year-old female with a massive ganglioglioma containing anaplastic oligodendroglioma apparently arising from the thalamus. Two weeks after partial resection, she was started on a regimen including escalated doses of topotecan in combination with a fixed-dosage intensification regimen of cisplatin, cyclophosphamide and vincristine with subsequent hyperfractionated external beam radiotherapy. She currently has stable disease.
journal_name
Pediatr Neurosurgjournal_title
Pediatric neurosurgeryauthors
Johnson MD,Jennings MT,Toms STdoi
10.1159/000056042keywords:
subject
Has Abstractpub_date
2001-06-01 00:00:00pages
301-5issue
6eissn
1016-2291issn
1423-0305pii
56042journal_volume
34pub_type
杂志文章abstract::A 3-year-old boy presented with headaches, vomiting, lethargy and papilledema. Communicating hydrocephalus along with transependymal fluid absorption and meningeal contrast enhancement was identified on CT. The enhancement was initially thought to be the result of a partially treated meningitis (child was previously o...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000084862
更新日期:2005-01-01 00:00:00
abstract::Three patients with colloid cysts were identified among approximately 1,400 patients with brain tumors seen at the Hospital for Sick Children in Toronto between 1952 and 1992. These and 34 previously published cases of colloid cysts in children were reviewed. Colloid cysts are rare causes of headaches and papilloedema...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000120782
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Endoscopic third ventriculostomy (ETV) has gained wide popularity as a first-line treatment for obstructive hydrocephalus (OHC). We have been performing ETV since 1998. We report our experience with this technique in the management of OHC. METHODS:Between 1998 and 2007, we performed 49 ETV procedures in 46 ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000257525
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:Complications arising from the placement of ventriculoperitoneal (VP) shunts are well documented. A case of infertility is presented that was thought to result from factors related to the distal end of a VP shunt residing within a patient's abdomen. CLINICAL PRESENTATION:A 30-year-old female w...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000098391
更新日期:2007-01-01 00:00:00
abstract::The use of temporal lobectomy for the treatment of intractable complex partial seizures of temporal lobe origin has a long and successful history. When appropriately applied in children, excellent seizure control and neurodevelopmental progress are expected. This article reviews patient selection, evaluating the surgi...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000056036
更新日期:2001-05-01 00:00:00
abstract::Ewing sarcoma (ES) is an aggressive, primary bone malignancy with occasional soft tissue extension. Purely extra-osseous ES is rare. A primary intraspinal, intradural ES without bone involvement is exceedingly rare. ES may be differentiated from other primitive neuroectodermal tumors by molecular analysis. The authors...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000488767
更新日期:2018-01-01 00:00:00
abstract::Ongoing research in the etiology of neural tube defects is increasingly being directed towards the molecular mechanisms at work in the formation of these complex lesions. We undertook to review the family history of patients in a large myelomeningocele/spina bifida clinic in an effort to identify genetic trends in the...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120977
更新日期:1995-01-01 00:00:00
abstract::We report two children with hemihypertrophy and Chiari I malformation (CIM) and review the extant medical literature regarding CIM and overgrowth disorders. We propose that these two entities do not represent a spurious association but rather share a common dysembryology of mesoderm. ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000069820
更新日期:2003-05-01 00:00:00
abstract::We report here the first case of ruptured arteriovenous malformation (AVM) in a patient with Beckwith-Wiedemann syndrome (BWS). The subject was a 9-year-old boy exhibiting various abnormal features characteristic of BWS, who had undergone frequent surgical management for conditions such as umbilical hernia, polydactyl...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028854
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:Lateral meningocele syndrome (LMS) is an exceedingly rare connective tissue disease with phenotypic anomalies similar to those seen in Marfan syndrome, Ehler-Danlos syndrome, and Loeys-Dietz syndrome. However, this syndrome is invariably associated with the presence of multiple lateral thoracolumbar spinal m...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000504060
更新日期:2020-01-01 00:00:00
abstract::Wakeboarding is a relatively new and exciting sporting activity which is similar to water-skiing. While there have been several reports of water-skiing-related injuries, there has been nothing reported in the literature so far concerning injuries in wakeboarding. We present the case of a 14-year-old male who sustained...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028957
更新日期:2000-06-01 00:00:00
abstract::A rare case of a patient with Laurence-Moon-Biedl syndrome associated with hypothalamic hamartoma is described. The English-language literature contains no cases of patients with this association. The clinical manifestations of this syndrome, those of hypothalamic hamartomas, and the appearance of the tumors on magnet...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000120563
更新日期:1991-01-01 00:00:00
abstract::Radiotherapy has remained the mainstay of treatment for children with intrinsic, diffuse pontine tumors in spite of over 20 years of clinical trials attempting to validate the additional role of chemotherapy. Conventional phase II clinical trials conducted in patients with recurrent or progressive brainstem gliomas us...
journal_title:Pediatric neurosurgery
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1159/000121024
更新日期:1996-01-01 00:00:00
abstract::Holoprosencephaly is a rare congenital malformation resulting from an impaired midline division of the prosencephalon into distinct cerebral hemispheres. Hydrocephalus is a frequent problem among the few survivors with alobar holoprosencephaly (aHPE), its most severe form. The literature about neurosurgical management...
journal_title:Pediatric neurosurgery
pub_type:
doi:10.1159/000489856
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:An 11-month-old boy with autosomal recessive infantile osteopetrosis presented, 7 months after bone marrow transplantation, with normal ventricular size and life-threatening intracranial hypertension due to pansynostosis. METHODS:The cranial vault was expanded by using jackscrew distracters to upwardly adva...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000098381
更新日期:2007-01-01 00:00:00
abstract::Hemifacial spasm (HFS), generally a disease of the elderly, is caused by vascular compression of the seventh nerve. Vascular compression is thought to result from atherosclerotic changes within the vessels of the posterior fossa, and therefore rarely presents in childhood. Here we describe our experience with 12 patie...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121260
更新日期:1997-11-01 00:00:00
abstract::The optimal treatment for Dandy-Walker malformation is still controversial. Ventriculoperitoneal shunting, cystoperitoneal shunting or combinations are the most common surgical options in the management of this clinical entity. Endoscopic procedures like ventriculocystostomy, 3rd ventriculostomy or endoscopy-assisted ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000353610
更新日期:2012-01-01 00:00:00
abstract::Tumors located in the region of the foramen of Monro often present with signs and symptoms of obstructive hydrocephalus. Various types of lesions occur in this location. We describe a case of a dysembryoplastic neuroepithelial tumor of the septum pellucidum presenting with obstructive hydrocephalus and its successful ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000090464
更新日期:2006-01-01 00:00:00
abstract::There have been numerous reported cases of diffuse intravascular coagulation (DIC) or defibrination syndrome associated with head trauma, but very few reported cases associated with primary brain tumor. This report concerns the findings in a case of DIC associated with brain tumor surgery in an infant. The patient die...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120504
更新日期:1990-01-01 00:00:00
abstract::Seventy pediatric patients with brain and spinal cord tumors had cytogenetic analysis of 99 samples of their tumors. Successful analysis was accomplished in 95%. Tumors included 43 gliomas, 9 medulloblastomas and a variety of other lesions. Forty-three patients had normal chromosomes; 28 of these had benign tumors and...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120569
更新日期:1991-01-01 00:00:00
abstract::Optimal treatment for hydrocephalus related to Dandy-Walker syndrome (DWS) remains elusive. Patients with DWS-related hydrocephalus often require combinations of shunting systems to effectively drain both the supratentorial ventricles and posterior fossa cyst. We describe an endoscopic technique, whereby a frontally p...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000087486
更新日期:2005-09-01 00:00:00
abstract::We here describe the case of a boy with an atypical teratoid-rhabdoid tumor (ATRT) of the 4th ventricle at 1 year of age and a local tumor recurrence at 19 months of age. Due to brainstem infiltration, only incomplete tumor resection was possible each time. High-dose chemotherapy, stem cell transplantation and irradia...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000092366
更新日期:2006-01-01 00:00:00
abstract::Although unilateral epidural hematomas are well known, bilateral presentation, especially at the confluens sinuum, is uncommon, and its diagnosis may be delayed, thus causing morbidity. We report a case of acute posttraumatic cortical blindness due to epidural hematoma at the confluens sinuum caused by venous sinus te...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000068813
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Spinal cord injury (SCI) is a leading cause of morbidity and mortality among youth and adults. Secondary injury mechanisms within the spinal cord (SC) are well known to cause deterioration after an acute impact. Free radical scavengers are among the most studied agents in animal models of SCI. Edaravone is a...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000335400
更新日期:2011-01-01 00:00:00
abstract::Kernohan-Woltman notch phenomenon (KWNP) is an ipsilateral motor weakness due to compression of the contralateral cerebral peduncle. Most of the KWNP cases reported have been due to subdural hematomas, intracranial space-occupying lesions, and spontaneous bleeding of vascular malformations. In this study, we present t...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000474945
更新日期:2017-01-01 00:00:00
abstract::Primary germ cell tumors confined to the optic nerves and chiasm without suprasellar extension are uncommon. These tumors appear similar to chiasmatic gliomas on both computed tomography and magnetic resonance imaging, potentially resulting in treatment errors if the diagnosis is based on radiologic criteria alone. Un...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120927
更新日期:1995-01-01 00:00:00
abstract::The placement of a ventriculoperitoneal (VP) shunt is the most common form of treatment for hydrocephalus.The distal end of the VP shunt is commonly placed in the peritoneal cavity. Various complications of the distal end of the shunt have been described in the literature.We report an unusual case of perforation of th...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000204904
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Composite-type split spinal cord malformation (SCM) is very rare and results from 2 separate foci of ectoendodermal adhesions and endomesenchymal tracts leading to the development of SCM with an intervening normal cord in the same patient. Posterior spurs are even rarer. We report a unique case of composite ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000336752
更新日期:2011-01-01 00:00:00
abstract::The authors present aspects of the skull base in trigonocephalic children. Different patterns on clinical anthropometric investigation, bidimensional computer tomography (CT) scan and three-dimensional (3D) CT scan were studied. We present a series of 27 cases of trigonocephaly operated on in the department of pediatr...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120591
更新日期:1991-01-01 00:00:00
abstract::In order to determine the optimal valve pressure setting during the first weeks in neonates after implantation of programmable Hakim valves and to analyze the benefits and possible side effects of a new treatment protocol in this age group, we performed this prospective study. In 20 consecutive newborns less than 5 we...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000056052
更新日期:2002-04-01 00:00:00