Management Strategies for Hydrocephalus in Alobar Holoprosencephaly: A Case Report and Discussion.

Abstract:

:Holoprosencephaly is a rare congenital malformation resulting from an impaired midline division of the prosencephalon into distinct cerebral hemispheres. Hydrocephalus is a frequent problem among the few survivors with alobar holoprosencephaly (aHPE), its most severe form. The literature about neurosurgical management of hydrocephalus in this condition is limited and dispersed, and there are still some points that need to be resolved. We report the case of a newborn with aHPE, hydrocephalus, and central diabetes insipidus. We delineate the complexity of the management of these patients and emphasize the benefits of using an initial programmable shunt valve. Further discussion about management strategies includes reviewing previous reports and the benefits of shunting for hypothalamic osmoreceptor function.

journal_name

Pediatr Neurosurg

journal_title

Pediatric neurosurgery

authors

Sarica C,Yucetas C,Ozen A,Ucler N,Konca C,Akar S

doi

10.1159/000489856

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

337-341

issue

5

eissn

1016-2291

issn

1423-0305

pii

000489856

journal_volume

53

pub_type

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