Placental bone morphogenetic protein (PLAB) gene expression in normal, pre-malignant and malignant human prostate: relation to tumor development and progression.

abstract：:Lung cancer is the leading cause of cancer mortality in the world. Although exposure to carcinogens is considered to be the main cause, genetic variation may contribute to lung cancer risk. Murine double minute 2, MDM2, is a key regulator of p53 activity and recently a polymorphism in the promoter region of the MDM2 g...

journal_title：International journal of cancer

authors： Lind H,Zienolddiny S,Ekstrøm PO,Skaug V,Haugen A

更新日期：2006-08-01 00:00:00

abstract：:Prolonged culture of hepatocytes isolated from mouse liver results in the spontaneous development of colonies of liver epithelial cells that can proliferate indefinitely in vitro. We established 5 such cell lines from C3H/HeJ mice (C3H) and 22 cell lines from C3H/HeJ x C57BL/6J F1 mice (C3B6F1) to investigate whether ...

journal_title：International journal of cancer

authors： Nishimori H,Ogawa K,Tateno H

更新日期：1994-10-01 00:00:00

abstract：:Data from a hospital-based matched case-control study with 531 male pairs were analyzed for risks of cancer of the lower urinary tract associated with previous employment and particular occupational exposures. Statistically significant odds ratios were obtained for ever-employment as mining workers (2.0), turners (2.3...

journal_title：International journal of cancer

authors： Claude JC,Frentzel-Beyme RR,Kunze E

更新日期：1988-03-15 00:00:00

abstract：:Vitamin D is well known for its important role in calcium and phosphor homeostasis. Recent research suggests that vitamin D also prevent some type of cancers. We studied solar vitamin D effective UV radiation (VD dose), dietary vitamin D, sun-seeking holidays, use of solarium, frequency of sunburn and breast cancer ri...

journal_title：International journal of cancer

authors： Edvardsen K,Veierød MB,Brustad M,Braaten T,Engelsen O,Lund E

更新日期：2011-03-15 00:00:00

abstract：:In this study we investigated the effect of Tax on nucleotide excision repair (NER) in human T-cell lines by using the host cell repair analysis of UVC-irradiated reporter plasmid. This analysis revealed a p53-dependent NER activity in wild type (w.t.) p53-containing T-cells and p53-independent NER in w.t. p53-lacking...

journal_title：International journal of cancer

authors： Schavinsky-Khrapunsky Y,Priel E,Aboud M

更新日期：2008-01-15 00:00:00

abstract：:We observed previously that two carbohydrate epitopes, extended type 1 chain Le(a)-Le(a) and Le(b)-Le(a), are expressed strongly in human gastric or colorectal cancer and cell lines derived therefrom, but their expression in human normal colorectal cells is highly limited. A monoclonal antibody, termed GNX-8, was esta...

journal_title：International journal of cancer

authors： Yang MC,Hsu FL,Handa K,Hakomori S,Lee MH,Liu LY,Chang SY,Ting J,Wen JY,Ishida I,Chang TH

更新日期：2009-12-21 00:00:00

abstract：:The authors analyzed the HER2 status in early-stage nonrecurrent and recurrent breast cancer groups following breast-conserving treatment. Retrospective analyses of a group of 36 invasive early breast cancer (IBC) patients who developed a local recurrence as a first event and of a random control group of 69 IBC patien...

journal_title：International journal of cancer

authors： López-Guerrero JA,Llombart-Cussac A,Noguera R,Navarro S,Pellin A,Almenar S,Vazquez-Alvadalejo C,Llombart-Bosch A

更新日期：2006-04-01 00:00:00

abstract：:The androgen receptor (AR) gene is a transcription factor responsible for mediating the physiological effects of androgens. Evidence suggests that androgens and the androgen receptor are involved in uterine cell proliferation. A polymorphic CAG repeat in exon 1 of the AR gene encodes a polyglutamine tract that is inve...

journal_title：International journal of cancer

authors： McGrath M,Lee IM,Hankinson SE,Kraft P,Hunter DJ,Buring J,De Vivo I

更新日期：2006-03-01 00:00:00

abstract：:BALB/c and C3H- mice were given a single injection of methylcholanthrene (MCA) and were tested at various times thereafter for immunologic reactivity and resistance to syngeneic tumor challenge. MCA treatment did not affect the rejection of H-2-incompatible tumor allografts, the rejection of H-2-compatible skin allogr...

journal_title：International journal of cancer

authors： Lill PH,Jessup JM,Kripke ML

更新日期：1978-04-15 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer mortality worldwide. Emerging evidence indicates that tumour cells release substantial amounts of RNA into the bloodstream, in which RNA strongly resists RNases and is present at sufficient levels for quantitative analyses. ...

journal_title：International journal of cancer

authors： Xu W,Zhou G,Wang H,Liu Y,Chen B,Chen W,Lin C,Wu S,Gong A,Xu M

更新日期：2020-05-15 00:00:00

abstract：:Hybridomas producing syngeneic monoclonal antibodies (MAbs) were prepared by fusion of spleen cells of BALB/c mice, which were immunized with sublethal doses of RMB-I cells. This cell line originates from a Rauscher virus (R-MuLV)-induced myeloid leukemia and forms tumors when re-inoculated into mice. MAbs were charac...

journal_title：International journal of cancer

authors： Berends D,Rhijnsburger EH,van Gaalen JL,van Houwelingen G,Zondervan PE,de Both NJ

更新日期：1988-07-15 00:00:00

abstract：:A clonal cell line, 1-1ras1000, transformed by the activated c-Ha-ras oncogene, does not form metastases after i.v. injection into mice (experimental metastasis assay). Here, we show that this cell line is useful as a recipient to detect metastasis-inducing genes, using a transfection assay. Cells (1-1ras1000) were su...

journal_title：International journal of cancer

authors： Tatsuka M,Ota T,Maeda M,Wada M,Yamagishi N,Taniguchi S,Seiki M,Odashima S

更新日期：1997-03-28 00:00:00

abstract：:The role of natural immune defense in the control of metastatic spread of tumor cells was evaluated by adapting an s.c.-grown, antigenic, but non-immunogenic rat fibrosarcoma (Bsp6S) to ascitic growth (BSp6A) in the strain of origin (BDX), where peritoneal cells display a high level of NK and macrophage activity. Para...

journal_title：International journal of cancer

authors： Zöller M

更新日期：1986-01-15 00:00:00

abstract：:In this report, we quantified HTLV-I provirus load using the AmpliSensor system, which utilizes fluorescence to measure PCR products. With this method, provirus loads could be measured within 6 hr, and the results obtained correlated well with those obtained by other methods. Samples from 256 blood donors, who were po...

journal_title：International journal of cancer

authors： Etoh K,Yamaguchi K,Tokudome S,Watanabe T,Okayama A,Stuver S,Mueller N,Takatsuki K,Matsuoka M

更新日期：1999-06-11 00:00:00

abstract：:In a hospital-based case-control study of esophageal cancer undertaken in Athens (1989-1991), 43 patients with incident esophageal squamous-cell carcinoma and 56 patients with incident esophageal adenocarcinoma were compared to 200 injury patients. Personal interviews were conducted in the hospital setting, and dietar...

journal_title：International journal of cancer

authors： Tzonou A,Lipworth L,Garidou A,Signorello LB,Lagiou P,Hsieh C,Trichopoulos D

更新日期：1996-11-04 00:00:00

abstract：:In mice as well as humans, cytotoxic T lymphocytes (CTL) specific for wild-type-sequence (wt) p53 peptides have been shown to react against a wide range of tumors, but not normal cells. As such, they are attractive candidates for developing broadly applicable cancer vaccines. Of particular interest is the potential of...

journal_title：International journal of cancer

authors： Cicinnati VR,Dworacki G,Albers A,Beckebaum S,Tüting T,Kaczmarek E,DeLeo AB

更新日期：2005-03-01 00:00:00

abstract：:We recently reported the identification of a human SART3 gene that encodes a tumor-rejection antigen recognized by cytotoxic T lymphocytes (CTLs). The squamous-cell carcinoma antigen recognized by T cells-3 (SART3) is an RNA-binding protein expressed in the nucleus of the majority of proliferating cells, including nor...

journal_title：International journal of cancer

authors： Harada K,Yamada A,Yang D,Itoh K,Shichijo S

更新日期：2001-09-01 00:00:00

abstract：:Metastasis to the liver often occurs in patients during the natural course of pancreatic cancer. Using carcinoma cell lines established from 9 such patients, we examined phenotypes of cell lines to search for correlations with their potential to metastasize to the liver. Anti-asialo GMI-treated nude mice were used. PC...

journal_title：International journal of cancer

authors： Kishimoto T,Ishikura H,Kimura C,Takahashi T,Kato H,Yoshiki T

更新日期：1996-08-22 00:00:00

abstract：:The alpha 5 beta 1 integrin (CD49e/CD29), a heterodimeric membrane protein, is the "classical" fibronectin receptor on many cell types. During B-cell ontogeny, expression of the alpha 5-subunit is developmentally regulated. The alpha 5 beta 1 is decisive for migration on fibronectin substrate and very likely cooperate...

journal_title：International journal of cancer

authors： Blase L,Daniel PT,Koretz K,Schwartz-Albiez R,Möller P

更新日期：1995-03-16 00:00:00

abstract：:Histologic characteristics of bladder cancer in Boston, USA, Manchester, UK, and Nagoya, Japan, were evaluated. In each of these areas broadly-based series of cases were assembled during a collaborative case-control study. The present analysis was based on 589 cases in Boston, 484 cases in Manchester, and 241 cases in...

journal_title：International journal of cancer

authors： Morrison AS,Proppe KH,Verhoek WG,Aoki K,Leck I,Ohno Y,Obata K

更新日期：1982-12-15 00:00:00

abstract：:Seven-day-old mouse embryos were transplanted under the kidney capsule of adult syngeneic recipients which were either X-irradiated, treated with cyclophosphamide, splenectomized or immunized with teratocarcinoma cell lines prior to embryonic transplantation. The yield of malignant tumors was decreased in preirradiate...

journal_title：International journal of cancer

authors： Damjanov I,Bagasra O,Dominis M,Solter D

更新日期：1982-12-15 00:00:00

abstract：:We, and others, have recently shown that recombinant feline leukaemia viruses (FeLV) containing the myc gene (FeLV-myc) occur in up to 30% of naturally occurring cases of T-cell lymphosarcoma. Investigation of the disease spectrum of two FeLV-myc isolates showed that they induced clonal or oligoclonal T-cell tumours a...

journal_title：International journal of cancer

authors： Onions D,Lees G,Forrest D,Neil J

更新日期：1987-07-15 00:00:00

abstract：:The present studies investigated the expression of the platelet-derived growth factor (PDGF) and PDGF-receptor genes in human meningiomas. Northern blot analysis demonstrated that all meningiomas examined expressed both the c-sis/PDGF-2 proto-oncogene and the PDGF-receptor gene. In situ hybridization localized the c-s...

journal_title：International journal of cancer

authors： Maxwell M,Galanopoulos T,Hedley-Whyte ET,Black PM,Antoniades HN

更新日期：1990-07-15 00:00:00

abstract：:Data are limited regarding cancer risk in human immunodeficiency virus (HIV)-infected persons with modest immunosuppression, before the onset of acquired immunodeficiency syndrome (AIDS). For some cancers, risk may be affected by highly active antiretroviral therapy (HAART) widely available since 1996. We linked HIV/A...

journal_title：International journal of cancer

authors： Engels EA,Biggar RJ,Hall HI,Cross H,Crutchfield A,Finch JL,Grigg R,Hylton T,Pawlish KS,McNeel TS,Goedert JJ

更新日期：2008-07-01 00:00:00

abstract：:In this registry-based cohort study, we estimated the risk of human papillomavirus (HPV)-related anogenital premalignancies and cancer in renal transplant recipients (RTRs) compared to a nontransplanted comparison cohort. We identified all first-time RTRs in Denmark during 1990-2015 in a nationwide nephrology register...

journal_title：International journal of cancer

authors： Reinholdt K,Thomsen LT,Dehlendorff C,Larsen HK,Sørensen SS,Haedersdal M,Kjaer SK

更新日期：2020-05-01 00:00:00

abstract：:MAGE genes encoding tumor-rejection antigens recognized by cytotoxic T lymphocytes are expressed at the mRNA level in various malignant tumors. We have investigated the expression of genes MAGE-1, -2, -3/-6 and -4a/-4b at the mRNA level in malignant and non-malignant ovarian tumors as well as in normal ovaries by reve...

journal_title：International journal of cancer

authors： Yamada A,Kataoka A,Shichijo S,Kamura T,Imai Y,Nishida T,Itoh K

更新日期：1995-12-20 00:00:00

abstract：:3H-HSV-2 DNA has been hybridized in situ to frozen sectioned tissue from human cervical biopsies. RNA complementary to the virus-specific probe was detected in cells undergoing pre-malignant changes, but not in the cells of the fully developed squamous-cell cancer. ...

journal_title：International journal of cancer

authors： McDougall JK,Galloway DA,Fenoglio CM

更新日期：1980-01-15 00:00:00

abstract：:With the aim of identifying innovative therapeutic strategies for osteosarcoma patients who are refractory to conventional chemotherapy, we analyzed the in vitro effects of the blockage of autocrine circuits. Since the insulin-like growth factor-I receptor (IGF-IR)-mediated loop is relevant to the growth of osteosarco...

journal_title：International journal of cancer

authors： Benini S,Baldini N,Manara MC,Chano T,Serra M,Rizzi S,Lollini PL,Picci P,Scotlandi K

更新日期：1999-02-09 00:00:00

abstract：:Use of dietary supplements is rising in countries where colorectal cancer is prevalent. We conducted a systematic literature review and meta-analyses of prospective cohort studies on dietary supplement use and colorectal cancer risk. We identified relevant studies in Medline, Embase and Cochrane up to January 2013. Or...

journal_title：International journal of cancer

authors： Heine-Bröring RC,Winkels RM,Renkema JM,Kragt L,van Orten-Luiten AC,Tigchelaar EF,Chan DS,Norat T,Kampman E

更新日期：2015-05-15 00:00:00

abstract：:The object of our multicenter retrospective study was to compare the new histologic World Health Organization (WHO) classification and the classical histologic Bernatz classification in terms of interobserver agreement and prognostic importance. The influence of coexisting diseases was also analyzed using the Charlson...

journal_title：International journal of cancer

authors： Rieker RJ,Hoegel J,Morresi-Hauf A,Hofmann WJ,Blaeker H,Penzel R,Otto HF

更新日期：2002-04-20 00:00:00