Determinants of sex hormone-binding globulin in normal postmenopausal women.

abstract：OBJECTIVE:To compare effectiveness and tolerability of quinagolide (CV 205-502) and cabergoline (CAB) treatments in 39 patients with prolactinoma. STUDY DESIGN:All 39 patients were treated first with quinagolide for 12 months and then with cabergoline for 12 months. A wash-out period was performed in all patients afte...

journal_title：Clinical endocrinology

authors： Di Sarno A,Landi ML,Marzullo P,Di Somma C,Pivonello R,Cerbone G,Lombardi G,Colao A

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Patients with idiopathic hypoparathyroidism (IH) require variable doses of calcium and 1-α-(OH)D. The reasons for such variability are not clear. As autoimmune mechanisms may play a role in IH, there is a possibility of coexistent coeliac disease with calcium/vitamin D malabsorption. OBJECTIVE:We assessed t...

journal_title：Clinical endocrinology

authors： Saha S,Saini S,Makharia GK,Datta Gupta S,Goswami R

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the role of pulsed tissue Doppler (TD) to identify left (LV) and right ventricular (RV) myocardial regional involvement in acromegaly. PATIENTS AND MEASUREMENTS:Thirty active acromegaly patients, free of diabetes mellitus, thyroid dysfunction, valvular and coronary heart d...

journal_title：Clinical endocrinology

authors： Galderisi M,Vitale G,Bianco A,Pivonello R,Lombardi G,Divitiis Od,Colao A

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:Appropriate replacement doses of glucocorticoid are important to determine in primary and secondary adrenal deficiency in children, both to avoid the risks of hypoglycaemia and adrenal crisis associated with undertreatment, and to avoid growth suppression and reduced final height potential associated with ste...

journal_title：Clinical endocrinology

authors： DeVile CJ,Stanhope R

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Aromatase deficiency (AD) caused by cytochrome P450 family 19 subfamily A polypeptide 1 (CYP19A1) variants is characterized by a deficiency in androgen-to-oestrogen conversion. OBJECTIVE:To investigate the clinical characteristics and accurate management of aromatase-deficient children. PATIENTS AND METHOD...

journal_title：Clinical endocrinology

authors： Fan L,Zhang B,Li L,Gong C

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:With increasing use of computed tomography and magnetic resonance imaging, pituitary adenomas are being discovered incidentally with increasing frequency. However, limited data are available concerning the clinical importance and natural history of such 'incicentalomas'. We have undertaken a prospective study...

journal_title：Clinical endocrinology

authors： Feldkamp J,Santen R,Harms E,Aulich A,Mödder U,Scherbaum WA

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:Non-tumour causes of hyperprolactinaemia, including prolactin-elevating drugs, must be excluded. There is a general view that such drugs are unlikely to raise serum PRL above 3000 mU/I, but the literature is confusing. We report 8 patients receiving treatment with neuroleptic drugs, whose serum PRL concentrat...

journal_title：Clinical endocrinology

authors： Pollock A,McLaren EH

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:We investigated the content and compared the molecular forms of parathyroid hormone-related protein in tumour tissue, plasma and pleural fluid. DESIGN:Measurement of parathyroid hormone-related protein in tumour extracts and biological fluids and comparison of the elution profiles of parathyroid hormone-rela...

journal_title：Clinical endocrinology

authors： Bowden SJ,Hughes SV,Ratcliffe WA

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVE:To determine whether early (4-8h) post-operative ACTH after trans-sphenoidal surgery (TSS) predicts long-term hypothalamic-pituitary-adrenal (HPA) axis function and to investigate early morning day 1 ACTH/cortisol variability using rapid sampling. DESIGN:Prospective observational study. METHODS:Participants...

journal_title：Clinical endocrinology

authors： English KA,Chikani V,Jang C,Dimeski G,Olson S,Inder WJ

更新日期：2020-12-28 00:00:00

abstract：:A 39-year-old woman presented with secondary amenorrhoea in the absence of galactorrhoea, hirsutism or virilization. Investigation revealed a strikingly elevated serum testosterone, dihydrotesterone, free testosterone and LH level. At laparotomy a large granulosa cell tumour was encountered and totally removed. Analys...

journal_title：Clinical endocrinology

authors： Taylor HC,Velasco ME,Flores SG,Berg G,Brown TR

更新日期：1982-12-01 00:00:00

abstract：OBJECTIVE:Surgery of bone metastases from differentiated thyroid carcinoma seems indicated in individual patients. This study was performed (1) to analyse retrospectively patients with bone metastases from differentiated thyroid carcinoma and (2) to evaluate the impact of surgery of bone metastases on survival. PATIEN...

journal_title：Clinical endocrinology

authors： Zettinig G,Fueger BJ,Passler C,Kaserer K,Pirich C,Dudczak R,Niederle B

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:Patients undergoing abdominal surgery often suffer from morbidity associated with increased protein catabolism. Therapeutic recombinant human insulin-like growth factor (rhIGF)-I has been proposed as a means of reversing this process. As IGFBPs modulate the bioavailability of the IGFs, we have studied the ch...

journal_title：Clinical endocrinology

authors： Cotterill AM,Mendel P,Holly JM,Timmins AG,Camacho-Hübner C,Hughes SC,Ross RM,Blum WF,Langford RM

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:The purpose of the study was to evaluate plasma inhibin as a marker of hydatidiform mole and to compare the results with intact human chorionic gonadotrophin (hCG) and its free beta-subunit. DESIGN:Serial determinations of the plasma concentrations of inhibin, intact human chorionic gonadotrophin and its fre...

journal_title：Clinical endocrinology

authors： Badonnel Y,Barbé F,Legagneur H,Poncelet E,Schweitzer M

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Previous studies suggesting effects of metyrapone on extra-adrenal corticosteroid metabolism have involved significant alterations in plasma cortisol. We have therefore studied effects of metyrapone on urinary excretion of steroids in a group of patients treated concurrently with hydrocortisone...

journal_title：Clinical endocrinology

authors： Raven PW,Checkley SA,Taylor NF

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:Poorly differentiated thyroid cancer (PDTC) is a rare, but aggressive thyroid cancer (TC) and a main cause of death from non-anaplastic follicular cell-derived TC. Assessing the risk of PDTC-related death and the risk of recurrence is important for clinicians. The recent American Thyroid Association (ATA) 201...

journal_title：Clinical endocrinology

authors： Walczyk A,Kopczyński J,Gąsior-Perczak D,Pałyga I,Kowalik A,Chrapek M,Hejnold M,Góźdź S,Kowalska A

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:Recovery of thyroid function in patients following hypothyroidism induced by 131I therapy for Graves' disease has been described, but only a few detailed clinical and biochemical studies of this phenomenon (transient hypothyroidism) have been published. The prevalence, mechanism, and final outcome of transien...

journal_title：Clinical endocrinology

authors： Aizawa Y,Yoshida K,Kaise N,Fukazawa H,Kiso Y,Sayama N,Hori H,Abe K

更新日期：1997-01-01 00:00:00

abstract：:The HLA-A and -B antigen distribution in 132 Hong Kong Chinese patients with Graves' disease, including 24 with thyrotoxic periodic paralysis, was compared with that in 110 controls. The HLA-DR antigen distribution in 68 patients was compared with that in 47 controls. The prevalence of Bw46 was significantly increased...

journal_title：Clinical endocrinology

authors： Hawkins BR,Ma JT,Lam KS,Wang CC,Yeung RT

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:The Interleukin (IL)-10 polymorphic variants -1082G/A, -819C/T and -592C/A were linked with obesity, metabolic syndrome, and type 2 diabetes (T2DM). We investigated the hypothesis that IL-10 promoter polymorphisms may be associated with the progression of diabetic nephropathy (DN). DESIGN:Case-controlled st...

journal_title：Clinical endocrinology

authors： Ezzidi I,Mtiraoui N,Kacem M,Mallat SG,Mohamed MB,Chaieb M,Mahjoub T,Almawi WY

更新日期：2009-03-01 00:00:00

abstract：:The results obtained with a new test of prolactin (PRL) release in six panhypopituitary patients as compared to fourteen normal subjects (eight females and six males) are presented. The test consists of the i.m. administration of 100 mg of sulpiride and the measurement of plasma PRL by a double antibody radioimmunoass...

journal_title：Clinical endocrinology

authors： Batrinos ML,Pavlou SN,Pitoulis SA,Sfikaki AP,Alexandrides TK,Piaditis GP

更新日期：1978-03-01 00:00:00

abstract：CONTEXT & OBJECTIVE:A recent paper by our group reported that regular aerobic exercise during pregnancy led to lower foetal IGF-I and IGF-II concentrations and a modest reduction in offspring birth weight when compared with the offspring of nontraining control participants. Maternal hormonal alterations in response to ...

journal_title：Clinical endocrinology

authors： Hopkins SA,Baldi JC,Cutfield WS,McCowan L,Hofman PL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:The low dose dexamethasone suppression test (DST) has been used to detect subtle variations in the feedback suppression of the hypothalamic-pituitary-adrenal axis, which may contribute to the pathogenesis of several diseases including depression, the metabolic syndrome and coronary artery disease. Little is ...

journal_title：Clinical endocrinology

authors： Reynolds RM,Bendall HE,Whorwood CB,Wood PJ,Walker BR,Phillips DI

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:Young women with Turner syndrome (TS) are known to be at risk for loss to medical follow-up. Recent literature indicates that there are disparities regarding transition readiness between different chronic conditions. So far, studies in young women with TS investigating their transition readiness compared to y...

journal_title：Clinical endocrinology

authors： Culen C,Herle M,Ertl DA,Fröhlich-Reiterer E,Blümel P,Wagner G,Häusler G

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Graves' Ophthalmopathy (GO) is a complex eye and orbital disorder that is uniquely linked to Graves' Hyperthyroidism (GH) and has traditionally been considered a cross-reactive immune response against the thyroid stimulating hormone receptor (TSHR) in orbital tissue. However, because there is no direct evide...

journal_title：Clinical endocrinology

authors： Wescombe L,Lahooti H,Gopinath B,Wall JR

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:The distinction between benign and malignant well-differentiated endocrine tumours is hard to achieve. The aim of the present study was to determine whether detection of telomerase or quantification of human telomerase reverse transcriptase protein subunit (hTERT) differ between benign and malignant endocrine...

journal_title：Clinical endocrinology

authors： Vezzosi D,Bouisson M,Escourrou G,Laurell H,Selves J,Seguin P,Pradayrol L,Caron P,Buscail L

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine (1) the diurnal variation in SHBG and (2) the inter-relationships of insulin, IGF-I, SHBG and IGFBP-1 over 24 hours in 10 women with anovulatory PCOS and compare them with weight-matched ovulatory controls. PATIENTS AND METHODS:The two groups comprised 10 anovulatory wom...

journal_title：Clinical endocrinology

authors： Hamilton-Fairley D,White D,Griffiths M,Anyaoku V,Koistinen R,Seppälä M,Franks S

更新日期：1995-08-01 00:00:00

abstract：:We describe here two patients with hypothyroidism due to pituitary-hypothalamic disease in whom basal thyrotrophin (TSH) levels measured by radioimmunoassay (RIA) were elevated yet when measured by a cytochemical bioassay (CBA) were found to be normal. This finding and the absence of the normal rise of thyroid hormone...

journal_title：Clinical endocrinology

authors： Petersen VB,McGregor AM,Belchetz PE,Elkeles RS,Hall R

更新日期：1978-05-01 00:00:00

abstract：OBJECTIVE:Adults with GH deficiency (GHD) exhibit changes in body composition. Studies of the effects of GH substitution on body composition have been short-term or not adequately controlled. The purpose of this study was to evaluate the long-term effects of GH on soft tissue using dual-energy X-ray absorptiometry (DEX...

journal_title：Clinical endocrinology

authors： Hansen TB,Vahl N,Jørgensen JO,Christiansen JS,Hagen C

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:Osteocalcin is a bone-specific protein secreted by osteoblasts and often used as a bone formation biomarker. Rodent studies have reported a hormonal role of osteocalcin on glucose metabolism, increasing insulin secretion and sensitivity and increasing energy expenditure. However, it is unknown whether osteoca...

journal_title：Clinical endocrinology

authors： Rochefort GY,Rocher E,Aveline PC,Garnero P,Bab I,Chappard C,Jaffré C,Benhamou CL

更新日期：2011-08-01 00:00:00

abstract：:The role of bromocriptine in the treatment of non-functioning pituitary tumours is not yet defined. Patients with these tumours who present with visual field defects usually undergo immediate surgery. Three consecutive patients are reported: each had rapid improvement in their visual field defects following bromocript...

journal_title：Clinical endocrinology

authors： D'Emden MC,Harrison LC

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVE:We wished to investigate the effects of nicotinamide and 3-aminobenzamide, well known as inhibitors of poly(ADP ribose) synthetase, on interferon-gamma-induced HLA-DR antigen expression using cultured human thyroid cells from patients with Graves' disease. DESIGN AND MEASUREMENTS:Cultured thyroid cells were ...

journal_title：Clinical endocrinology

authors： Hiromatsu Y,Sato M,Yamada K,Nonaka K

更新日期：1992-01-01 00:00:00