Age and history of cardiac disease as risk factors for cardiac complications after peripheral vascular surgery in diabetic patients.

Abstract:

OBJECTIVE:To examine the relationship of age and clinical factors to postoperative cardiovascular events in a cohort of diabetic patients undergoing peripheral vascular surgery. PATIENTS AND METHODS:In this cohort study, 316 diabetic patients were followed up prospectively after femoral-to-distal artery bypass surgery. The major end points of the study were all-cause mortality and cardiac morbidity (cardiac events defined as nonfatal myocardial infarction, unstable angina, and congestive heart failure). RESULTS:The overall postoperative cardiac event rate was 17.1% (54/316), with a 7.6% (24/316) rate of postoperative death or nonfatal myocardial infarction. Older diabetic patients (> or = 65 years) had a complication rate of 19.9% (43/216) compared with an 11.0% (11/100) complication rate in younger diabetic patients (< 65 years) (P = .02). Younger diabetic patients with a clinical history of coronary artery disease had an event rate of 18.2% (39/216) compared with an event rate of 2.4% (1/42) in younger diabetic patients without known cardiac disease (P = .02). In contrast, event rates were similar (20.7% [150/208] vs 18.2% [66/108]) in older diabetic patients with or without prior evidence of cardiac disease. CONCLUSION:Advanced age and clinical evidence of coronary artery disease are important determinants of postoperative outcome in diabetic patients undergoing peripheral vascular surgery.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Zarich SW,Pierce ET,Nesto RW,Mittleman MA,Bode RH,Kowalchuk G,Cohen MC

doi

10.4065/76.1.34

keywords:

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

34-8

issue

1

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(11)62077-6

journal_volume

76

pub_type

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