Abstract：
AIM:To compare sonographic measurements of fetal fat tissue in pregnancies complicated by gestational diabetes (GD), with patients undergoing either a diet only or a combined diet and insulin treatment, to those obtained in pregnancies with a normal glucose challenge test. METHODS:Forty-five singleton pregnancies complicated by GD but free of any other maternal disease known to affect fetal growth were recruited. GD was diagnosed by a 3-hour OGTT, and treatment was differentiated according to the glycemic profile. GD mothers were divided into two treatment groups: glycemic profile normalized by diet only treatment (n=16) and by combined diet and insulin treatment (n=29). Fetal biometry and subcutaneous fat tissue thickness of the anterior abdominal wall were sonographically evaluated at the time of diagnosis and every 4 weeks afterwards in both GD and normal glucose challenge test group (n=25). RESULTS:No differences were found in neonatal outcomes between combined diet and insulin treatment group and normal cases, whereas neonatal weight showed a statistically significant difference between diet only treatment group and healthy population. Abdominal circumference in fetuses from GD mothers and normal fetuses was similar, but there was a difference in the fetal fat tissue thickness at the time of diagnosis. CONCLUSION:Increased fetal fat tissue thickness in GD mothers at recruitment and its growth rate reduction during adequate treatment may be a new criterion for direct estimation of fetal metabolic status instead of the traditional indirect evaluation based on maternal glucose concentrations.
journal_name
Croat Med Jjournal_title
Croatian medical journalauthors
Rigano S,Ferrazzi E,Radaelli T,Cetin ET,Pardi Gkeywords:
subject
Has Abstractpub_date
2000-09-01 00:00:00pages
240-4issue
3eissn
0353-9504issn
1332-8166journal_volume
41pub_type
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journal_title：Croatian medical journal
pub_type： 杂志文章
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journal_title：Croatian medical journal
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journal_title：Croatian medical journal
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更新日期：2007-10-01 00:00:00
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journal_title：Croatian medical journal
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journal_title：Croatian medical journal
pub_type： 杂志文章
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更新日期：2000-12-01 00:00:00
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journal_title：Croatian medical journal
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doi：
更新日期：1999-09-01 00:00:00
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journal_title：Croatian medical journal
pub_type： 杂志文章
doi：
更新日期：2001-06-01 00:00:00
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pub_type： 杂志文章
doi：
更新日期：2004-12-01 00:00:00
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更新日期：2004-06-01 00:00:00
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journal_title：Croatian medical journal
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
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journal_title：Croatian medical journal
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doi：
更新日期：2004-02-01 00:00:00
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更新日期：2005-06-01 00:00:00
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journal_title：Croatian medical journal
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doi：
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journal_title：Croatian medical journal
pub_type： 杂志文章
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