Abstract:
:The specificity of the IgM receptor expressed by human T cells cultured in IgM-free media has been investigated. IgM receptors have been detected using a rosette system with ox erythrocytes coated with rabbit antibody (EA(IgM)), and the inhibitory capacity of different IgM fragments in the rosette system has been tested. It was found that F(c)5mu but not F(ab')2mu, nor monomeric IgM (8 S IgM) inhibited EA (IgM) rosette-forming cells. This indicates that the receptor present on the surface of T cells has affinity for a structure located in the Fc portion of the pentameric IgM.
journal_name
Eur J Immunoljournal_title
European journal of immunologyauthors
Ferrarini M,Moretta L,Mingari MC,Tonda P,Pernis Bdoi
10.1002/eji.1830060714keywords:
subject
Has Abstractpub_date
1976-07-01 00:00:00pages
520-1issue
7eissn
0014-2980issn
1521-4141journal_volume
6pub_type
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journal_title:European journal of immunology
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journal_title:European journal of immunology
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journal_title:European journal of immunology
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journal_title:European journal of immunology
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