Leptin and IGF-I levels in unconditioned male volunteers after short-term exercise.

Abstract:

:We have previously shown that serum gonadotropins, particularly LH, decline after acute exercise in male volunteers. The mechanism for this decline is unknown. Plasma leptin and IGF-I concentrations were measured in seven male volunteers after acute exercise to exhaustion using the Bruce protocol. Leptin concentrations declined following exercise reaching nadir values 30-120 min after exercise. As anticipated, plasma IGF-I concentrations showed a transient rise immediately after exercise falling thereafter to nadir levels 60-90 min after exercise before returning towards baseline levels. In view of the previously described decline in gonadotropin release after acute exercise, the decline in plasma leptin levels, perhaps related to the rise in IGF-I, may play a role in exercise-induced inhibition of gonadotropin release presumably by inhibition of GnRH secretion.

journal_title

Psychoneuroendocrinology

authors

Elias AN,Pandian MR,Wang L,Suarez E,James N,Wilson AF

doi

10.1016/s0306-4530(99)00070-0

keywords:

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

453-61

issue

5

eissn

0306-4530

issn

1873-3360

pii

S0306-4530(99)00070-0

journal_volume

25

pub_type

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