Abstract：
:Most adrenal incidentalomas are nonfunctioning cortical adenomas that do not require surgery. Operative treatment is indicated if the incidentaloma has malignant features as seen during the radiologic workup, is hormonally active, or grows during follow-up. A conservative attitude is justified in asymptomatic patients if we know that the natural course of these tumors is not disadvantageous. We followed a group of patients treated by observation to determine the natural course of adrenal incidentalomas. Altogether 30 incidentalomas in 27 patients were detected in the Helsinki University Central Hospital from June 1981 through December 1992 and were re-examined during 1997. The patients were evaluated clinically, and hormonal testing was done by performing a 1-mg overnight dexamethasone suppression test; the next day we measured the 24-hour urinary excretion of vanillylmandelic acid, metanephrines and normetanephrines, and serum potassium. Magnetic resonance imaging (MRI) was used to determine the size of the tumor. If the patient had died during the follow-up period, the causes of death from the death certificates and autopsy reports were reviewed. The mean follow-up was 7 years. Nine patients had died, with none of deaths related to the incidentaloma. Sixteen patients were evaluated clinically and by the basic hormonal tests and MRI; none showed any signs of hormonal activity or features of malignancy. Two patients did not want to be reexamined but stated that they were asymptomatic. This follow-up study supports the conclusion that conservative therapy is justified because the growth tendency of adrenal incidentalomas is slow and they seem to remain hormonally inactive.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Sirén J,Tervahartiala P,Sivula A,Haapiainen Rdoi
10.1007/s002689910095keywords:
subject
Has Abstractpub_date
2000-05-01 00:00:00pages
579-82issue
5eissn
0364-2313issn
1432-2323journal_volume
24pub_type
杂志文章abstract：BACKGROUND:When needle core biopsies (NCBs) of the breast reveal fibroepithelial lesions (FELs), excision is often performed to rule out a phyllodes tumor (PT), despite low malignancy rates. Consequently, the natural history of observed FELs is not well described. We analyzed the malignancy risk in excised FELs and the...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05385-6
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:There is no clear consensus on the efficacy and safety of hyaluronate-carboxymethylcellulose membrane (Seprafilm) for preventing postoperative abdominal adhesion. This study is a meta-analysis of the available evidence. METHODS:A search of the MEDLINE, EMBASE, and the Cochrane Library identified eight studi...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
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更新日期：2007-11-01 00:00:00
abstract：BACKGROUND:This study was undertaken to determine the efficacy of the clinical indications for performing staging laparoscopy for locally advanced gastric cancer to detect peritoneal metastasis or positive cytology findings. METHODS:The study included 231 patients with T4 gastric cancer without hematogenous or clinica...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1290-5
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Enhanced recovery (ERAS) guidelines do not differentiate between left- and right-sided colectomies, but differences in recovery have been reported for the two procedure types. We aimed to compare compliance with the ERAS protocol and outcomes after right versus left colectomy. METHODS:Between June 2011 and ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3563-5
更新日期：2016-10-01 00:00:00
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journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验,评审
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更新日期：1993-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0455-0
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1897-1
更新日期：2013-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 历史文章,杂志文章
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更新日期：1999-08-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：1999-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2445-3
更新日期：2014-06-01 00:00:00
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journal_title：World journal of surgery
pub_type： 传,历史文章,杂志文章
doi：10.1007/s002689900238
更新日期：1997-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00295914
更新日期：1995-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0455-y
更新日期：2010-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9354-2
更新日期：2008-02-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4390-z
更新日期：2018-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0187-0
更新日期：2002-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-3988-5
更新日期：2017-08-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05471-9
更新日期：2020-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900498
更新日期：1998-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-019-04972-6
更新日期：2019-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658869
更新日期：1989-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900626
更新日期：1999-10-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4083-7
更新日期：2017-11-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3006-8
更新日期：2015-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4121-5
更新日期：2017-12-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658701
更新日期：1993-05-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0063-x
更新日期：2009-08-01 00:00:00
abstract：:In the original article there is an error in Fig. 2. Following is the corrected figure. ...
journal_title：World journal of surgery
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00268-018-04886-9
更新日期：2019-03-01 00:00:00
abstract：INTRODUCTION:Parathyroid cysts are rare but clinically significant lesions. They can be functional, mistaken for a thyroid cyst, and/or managed nonoperatively on occasion. METHODS:We identified seven patients (1 male, 6 females) with the diagnosis of parathyroid cyst from 1998 to 2003. RESULTS:Altogether, 33% of the ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0748-8
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:We describe a new technique of segment-based liver resection by inserting a 6 French balloon catheter into the portal vein via a branch of the superior mesenteric vein. MATERIALS AND METHODS:The catheter was guided into the relevant portal branch supplying the liver segment that contained the tumor. Injecti...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9043-1
更新日期：2007-06-01 00:00:00
