Detection of anterior horn lesions by MRI in central European tick-borne encephalomyelitis.

Abstract:

:We report a case of central European tick-borne encephalitis with cervical myelitis presenting clinically as a lower motor neuron syndrome of the upper limbs with proximal asymmetrical pareses and atrophies. There were no sensory deficits nor signs of lesions of the spinal pathways or signs of encephalitis or meningitis. The affected motor fibers of the upper limbs were electrically inexcitable, but sensory findings were normal. Electromyography of the paralyzed muscles revealed pathological denervation activity without voluntary activation. The initial magnetic resonance imaging (MRI) showed a large hyperdense lesion in the anterior part of the cervical cord from C3 to T1. Despite the fact that MRI changes disappeared completely within 6 weeks the patient showed only little improvement in the paralyzed muscles after 6 months. To our knowledge, these MRI changes in patients with tick-borne encephalitis, consistent with an isolated anterior horn lesion, have never been reported previously. The course may have been aggravated by an initial antibiotic treatment with cephalosporins.

journal_name

J Neurol

journal_title

Journal of neurology

authors

Beer S,Brune N,Kesselring J

doi

10.1007/s004150050537

keywords:

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

1169-71

issue

12

eissn

0340-5354

issn

1432-1459

journal_volume

246

pub_type

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