Abstract：
INTRODUCTION:We present the results of a 42 year long-term follow-up of 44 patients (19 males, 25 females) with childhood-onset schizophrenia (COS, age at onset: 7-14 years) who could be traced for a second follow-up examination 27 years after the first follow-up. METHOD:Data from interviews, clinical records, premorbid and social disability assessments were evaluated for statistical analyses. The symptomatology observed during the whole course of illness was rediagnosed by DSM-IV criteria. RESULTS:The paranoid, catatonic, and schizoaffectives subtypes appeared most frequently. There have been no gender differences in age of first psychiatric symptoms (AFS), AFPS, and age of first hospitalization. Kaplan-Meier's survival-analysis carried out for AFPS with sex as the grouping factor revealed that the cumulative prevalence appears to be earlier in females (between 7 and 15 years) than in males (between 10 and 18 years). Of the 44 patients 50 % had a continuing severe course. Patients with onset before 12 years of age were characterized by a chronic/insidious onset, marked premorbid abnormalities, and by a poorer remission. Premorbid features of social withdrawal and reluctance indicated a risk for social disability within the later course. CONCLUSION:COS, as a rare but severe variant of schizophrenia, frequently develops from premorbid social maladaptation to an insidious onset but is subsequently followed by a transition to a course and outcome not distinguishable from that of adult-onset schizophrenia.
journal_name
Eur Child Adolesc Psychiatryjournal_title
European child & adolescent psychiatryauthors
Eggers C,Bunk D,Volberg G,Röpcke Bdoi
10.1007/pl00010687keywords:
subject
Has Abstractpub_date
1999-01-01 00:00:00pages
I21-8eissn
1018-8827issn
1435-165Xjournal_volume
8 Suppl 1pub_type
杂志文章,评审abstract：BACKGROUND:Children with conduct disorders and their families come into contact with a range of community and specialist agencies. METHODS:The aim of this study was to establish the lifetime service utilisation rates among children with conduct disorders from the Great Britain National Study (N = 10,438), and to exami...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-003-0330-6
更新日期：2003-10-01 00:00:00
abstract：:The main aim of this study was to examine the moderating effects of attention deficit hyperactivity disorder (ADHD) on anxiety disorders in children. Data were analyzed from a large referred sample of children with anxiety disorder without comorbid ADHD (anxiety disorder, N = 253), anxiety disorder plus comorbid ADHD ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-009-0041-8
更新日期：2010-02-01 00:00:00
abstract：:The Revised Behaviour Summarized Evaluation Scale (BSE-R) was developed for the objective evaluation of autistic behaviours in order to facilitate the recording of the evolution of developmentally disabled children. Among its 29 items, 13 items that precisely describe the degree of autistic behaviours were extracted b...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/BF01980489
更新日期：1995-10-01 00:00:00
abstract：:The link between attention deficit/hyperactivity disorder (ADHD) and elevated body weight/obesity can be regarded as well established. Because oppositional defiant disorder (ODD)/conduct disorder (CD) has also been found to be associated with these characteristics and ADHD and ODD/CD often occur comorbidly, we investi...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-013-0489-4
更新日期：2014-07-01 00:00:00
abstract：:One third of children with autistic spectrum disorders (or pervasive developmental disorders) enter that state by regression from a more normal prior development at the onset of epilepsy or epileptiform abnormality in the electroencephalogram. In a very small proportion structural lesions of the temporal lobes are dis...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s007870050128
更新日期：1999-09-01 00:00:00
abstract：:Severe posttraumatic stress symptoms (PTSS) are connected to a variety of health-related and interpersonal problems, among them are the insecure attachment orientations. However, psychotherapy seems to improve not only PTSS but also attachment insecurities. In a large multicenter, randomized clinical trial, the attach...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-020-01637-x
更新日期：2020-09-12 00:00:00
abstract：:Autonomic activity and respiration were studied in Rett syndrome (RS) and age matched controls. Breathing movements were monitored using a pletysmograph around the chest. Sympathetic activity was monitored by measuring blood pressure (BP) using the Finapres. Cardiac parasympathetic activity was monitored by measuring ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:Autistic spectrum disorders (ASD) are characterised by attention deficits in communication and social interactions and a lack of interest in people. Data are mostly based on clinical situations. However, recent studies have shown a more mixed situation where children with ASD (ASD children) displayed interest towards ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-014-0528-9
更新日期：2015-01-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-017-1047-2
更新日期：2018-03-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
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更新日期：2017-03-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-020-01697-z
更新日期：2021-01-04 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-009-0057-0
更新日期：2010-06-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,meta分析,评审
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更新日期：2018-08-01 00:00:00
abstract：:The aim was to study the association between preschool behavioural problems and emotional symptoms in 10- to 12-year-old children. The study was based on the Aarhus Birth cohort, Denmark, and included 1,336 children. Based on the parent-administered preschool behaviour questionnaire (PBQ), we identified three not mutu...
journal_title：European child & adolescent psychiatry
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doi：10.1007/s00787-010-0128-2
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
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更新日期：1996-09-01 00:00:00
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journal_title：European child & adolescent psychiatry
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更新日期：2013-06-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-013-0409-7
更新日期：2013-11-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,随机对照试验
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更新日期：2013-09-01 00:00:00
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journal_title：European child & adolescent psychiatry
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
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更新日期：1995-01-01 00:00:00
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journal_title：European child & adolescent psychiatry
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journal_title：European child & adolescent psychiatry
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,评审
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更新日期：2010-03-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章,多中心研究
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更新日期：2015-04-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-019-01321-9
更新日期：2019-12-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-009-0015-x
更新日期：2009-09-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
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更新日期：2009-01-01 00:00:00
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journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s007870050101
更新日期：1999-12-01 00:00:00
abstract：BACKGROUND:The process of childbirth and its complications have been related to the newborn's condition and to development at later ages. In this study, we examine how mode of delivery and delivery complications are related to the behavior and cortisol reactivity of infants during the first 2 months. METHODS:Delivery ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
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更新日期：2007-09-01 00:00:00
abstract：:Secular trends in the criminal activity of conduct disordered adolescents admitted as psychiatric in-patients in Norway were examined. A nationwide sample of 650 adolescents hospitalised with DSM-IV Conduct Disorder during the years 1963-1990 was followed up 12-33 years after index hospitalisation by register linkage ...
journal_title：European child & adolescent psychiatry
pub_type： 杂志文章
doi：10.1007/s00787-005-0444-0
更新日期：2005-07-01 00:00:00
