Identification of behaviour profiles with a population of autistic children using multivariate statistical methods.


:The Revised Behaviour Summarized Evaluation Scale (BSE-R) was developed for the objective evaluation of autistic behaviours in order to facilitate the recording of the evolution of developmentally disabled children. Among its 29 items, 13 items that precisely describe the degree of autistic behaviours were extracted by Principal Component Analysis. We hypothesised that these relevant behaviours could differentiate autistic behaviour profiles in a population of children previously diagnosed as typically autistic. For this purpose, we used an original multivariate descriptive statistical approach, Correspondence Analysis, which can help in detecting structural relationships among variables. In a population of autistic children initially diagnosed using DSM-III-R criteria, this procedure proved effective in identifying new main dimensions of behaviours among the 13 previously defined core autistic symptoms. Cluster analysis, which followed factorial analysis, allowed the identification of three meaningful behaviour profiles separated principally on the basis of two main functions, perception and imitation, which have been always considered to be fundamentally involved in autistic syndrome. The individualisation of homogeneous subgroups of children on the basis of the behavioural evaluation provides a potentially useful starting point for further biological and therapeutic studies.


Roux S,Malvy J,Bruneau N,Garreau B,Guérin P,Sauvage D,Barthélémy C




Has Abstract


1995-10-01 00:00:00












  • Quantified multidimensional assessment of autism and other pervasive developmental disorders. Application for bioclinical research.

    abstract::A large number of investigation techniques are used to establish the relationships between the clinical and biological data which are necessary for physiopathological analysis in the field of developmental disorders. It therefore seemed necessary to develop a quantified grouping system, based on developmental assessme...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Hameury L,Roux S,Barthélémy C,Adrien JL,Desombre H,Sauvage D,Garreau B,Lelord G

    更新日期:1995-04-01 00:00:00

  • Comorbidity and subgroups in childhood autism.

    abstract::The objective of this study was to identify clinical subgroups in children with childhood autism and to examine comorbidity in each subgroup. The study was based on medical records of 30 inpatients referred to a specialist ward for children with pervasive developmental disorders. Eighteen consecutive patients with an ...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Bonde E

    更新日期:2000-03-01 00:00:00

  • Anxiety risk SNPs on chromosome 2 modulate arousal in children in a fear generalization paradigm.

    abstract::Alterations in fear learning/generalization are considered to be relevant mechanisms engendering the development of anxiety disorders being the most prevalent mental disorders. Although anxiety disorders almost exclusively have their first onset in childhood and adolescence, etiological research focuses on adult indiv...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Reinhard J,Drepper C,Weber H,Schiele MA,Kneer K,Mittermeier A,Frey L,Reif A,Pauli P,Domschke K,Deckert J,Romanos M

    更新日期:2020-09-01 00:00:00

  • Perceptions of family relationships in adolescents with anorexia nervosa and their unaffected sisters.

    abstract::The family relationships of patients with anorexia nervosa (AN) have been extensively studied over recent years. However, using case-control designs with unrelated controls is subject to various cultural and familial biases. Studying subjective differential perceptions of family relationships in sister-pairs discordan...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Karwautz A,Nobis G,Haidvogl M,Wagner G,Hafferl-Gattermayer A,Wöber-Bingöl C,Friedrich MH

    更新日期:2003-06-01 00:00:00

  • Longitudinal outcomes of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS).

    abstract::Little is known about the natural history of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS). This study prospectively followed 33 children with PANDAS for up to 4.8 years (mean 3.3 ± 0.7 years) after enrollment in a 24-week randomized, double-blind, place...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,随机对照试验


    authors: Leon J,Hommer R,Grant P,Farmer C,D'Souza P,Kessler R,Williams K,Leckman JF,Swedo S

    更新日期:2018-05-01 00:00:00

  • The ESSEN study of childhood-onset schizophrenia: selected results.

    abstract:INTRODUCTION:We present the results of a 42 year long-term follow-up of 44 patients (19 males, 25 females) with childhood-onset schizophrenia (COS, age at onset: 7-14 years) who could be traced for a second follow-up examination 27 years after the first follow-up. METHOD:Data from interviews, clinical records, premorb...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,评审


    authors: Eggers C,Bunk D,Volberg G,Röpcke B

    更新日期:1999-01-01 00:00:00

  • Neuroanatomical changes associated with conduct disorder in boys: influence of childhood maltreatment.

    abstract::Childhood maltreatment (CM) poses a serious risk to the physical, emotional and psychological well-being of children, and can advance the development of maladaptive behaviors, including conduct disorder (CD). CD involves repetitive, persistent violations of others' basic rights and societal norms. Little is known abou...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Gao Y,Jiang Y,Ming Q,Zhang J,Ma R,Wu Q,Dong D,Sun X,He J,Cao W,Yuan S,Yao S

    更新日期:2021-01-04 00:00:00

  • Long-term course of ADHD symptoms from childhood to early adulthood in a community sample.

    abstract::Comparatively little information is available from population-based studies on subgroup trajectories of attention-deficit/hyperactivity disorder (ADHD) core symptoms of inattention and hyperactivity-impulsivity (particularly as defined by DSM-IV and ICD-10). Recent report of a subgroup with high and increasing inatten...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Döpfner M,Hautmann C,Görtz-Dorten A,Klasen F,Ravens-Sieberer U,BELLA study group.

    更新日期:2015-06-01 00:00:00

  • Neuro-physiological correlates of sluggish cognitive tempo (SCT) symptoms in school-aged children.

    abstract::This study was the first to examine the relationship between neurophysiological abnormalities and symptoms of sluggish cognitive tempo (SCT) in children. Thirty children aged 6-12 years were recruited. Their heart rate variability (HRV) was measured under resting and warning signal conditions. At rest, the children's ...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Yung TWK,Lai CYY,Chan JYC,Ng SSM,Chan CCH

    更新日期:2020-03-01 00:00:00

  • Societal costs and quality of life of children suffering from attention deficient hyperactivity disorder (ADHD).

    abstract:BACKGROUND:The impact of attention deficit hyperactive disorder (ADHD) in the Netherlands on health care utilisation, costs and quality of life of these children, as well as of their parents is unknown. OBJECTIVE:The aim of this study was to assess the direct medical costs of patients suffering from ADHD and their qua...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Hakkaart-van Roijen L,Zwirs BW,Bouwmans C,Tan SS,Schulpen TW,Vlasveld L,Buitelaar JK

    更新日期:2007-08-01 00:00:00

  • Child and adolescent psychiatry training in Europe: differences and challenges in harmonization.

    abstract:OBJECTIVE:To investigate the current situation of Child and Adolescent Psychiatry (CAP) training in European countries. In addition, current agenda of different organizations in order to harmonize the training across Europe are reported. METHOD:In order to collect data for this descriptive documentation on CAP trainin...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Karabekiroglu K,Doğangün B,Hergüner S,von Salis T,Rothenberger A

    更新日期:2006-12-01 00:00:00

  • Treating attention-deficit/hyperactivity disorder beyond symptom control alone in children and adolescents: a review of the potential benefits of long-acting stimulants.

    abstract::Attention-deficit/hyperactivity disorder (ADHD), one of the most common neuropsychiatric conditions of childhood, often has a chronic course and persists into adulthood in many individuals. ADHD may have a clinically important impact on health-related quality of life in children, a significant impact on parents' emoti...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,评审


    authors: Buitelaar J,Medori R

    更新日期:2010-04-01 00:00:00

  • Adolescent kleptomania treated with naltrexone--a case report.

    abstract::Kleptomania, an often secret inability to resist the impulse to steal objects not needed for personal use or their monetary value, is an underrecognized disorder that is unknown to many clinicians. Kleptomania has gone virtually non mentioned in the adolescent literature, despite the fact that kleptomania often has it...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Grant JE,Kim SW

    更新日期:2002-04-01 00:00:00

  • Eight-year incidence of psychiatric disorders and service use from adolescence to early adulthood: longitudinal follow-up of the Mexican Adolescent Mental Health Survey.

    abstract::Half of mental disorders have their first onset before adulthood when the presence of a disorder may be particularly disruptive to developmental milestones. Retrospective prevalence estimates have been shown to underestimate the burden of mental illness and scarce data are available on the incidence of disorders throu...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Benjet C,Borges G,Méndez E,Albor Y,Casanova L,Orozco R,Curiel T,Fleiz C,Medina-Mora ME

    更新日期:2016-02-01 00:00:00

  • Influence of assessment instrument on ADHD diagnosis.

    abstract::We compared four instruments commonly used to screen for and diagnose Attention-Deficit/Hyperactivity Disorder (ADHD) in children. The Bergen Child Study included a DSM-IV ADHD symptom list and the Strengths and Difficulties Questionnaire (SDQ) as screen in Phase one. Phase two included the parent Development and Well...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Posserud MB,Ullebø AK,Plessen KJ,Stormark KM,Gillberg C,Lundervold AJ

    更新日期:2014-04-01 00:00:00

  • Get secure soon: attachment in abused adolescents and young adults before and after trauma-focused cognitive processing therapy.

    abstract::Severe posttraumatic stress symptoms (PTSS) are connected to a variety of health-related and interpersonal problems, among them are the insecure attachment orientations. However, psychotherapy seems to improve not only PTSS but also attachment insecurities. In a large multicenter, randomized clinical trial, the attach...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Rimane E,Steil R,Renneberg B,Rosner R

    更新日期:2020-09-12 00:00:00

  • Psychiatric disorders in 8-9-year-old children based on a diagnostic interview with the parents.

    abstract::Using three questionnaires, the Rutter Parent Questionnaire (RA2), The Rutter Teacher Questionnaire (RB2) and the Children's Depression Inventory (CDI), we screened 8-9-year-old children representing a total annual birth cohort (N = 60007) in Finland. In a second stage we interviewed the parents of 119 screen negative...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Almqvist F,Puura K,Kumpulainen K,Tuompo-Johansson E,Henttonen I,Huikko E,Linna S,Ikäheimo K,Aronen E,Katainen S,Piha J,Moilanen I,Räsänen E,Tamminen T

    更新日期:1999-01-01 00:00:00

  • Maternal versus adolescent reports of suicidal behaviors: a nationwide survey in Israel.

    abstract::Community and nationwide surveys on adolescent suicidal behaviors using clinical interviews are not abundant. Rates of self-reported suicide attempts in community samples vary greatly between 1 and 20 %. In general, adolescent and parental agreement in child psychiatry practice is low, and their agreement with regard ...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Zalsman G,Shoval G,Mansbach-Kleinfeld I,Farbstein I,Kanaaneh R,Lubin G,Apter A

    更新日期:2016-12-01 00:00:00

  • Interpersonal sensitivity and persistent attenuated psychotic symptoms in adolescence.

    abstract::Interpersonal sensitivity defines feelings of inner-fragility in the presence of others due to the expectation of criticism or rejection. Interpersonal sensitivity was found to be related to attenuated positive psychotic symptom during the prodromal phase of psychosis. The aims of this study were to examine if high le...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Masillo A,Brandizzi M,Valmaggia LR,Saba R,Lo Cascio N,Lindau JF,Telesforo L,Venturini P,Montanaro D,Di Pietro D,D'Alema M,Girardi P,Fiori Nastro P

    更新日期:2018-03-01 00:00:00

  • Taking a closer look: autonomic dysregulation in socially anxious children.

    abstract::Previous research on autonomic characteristics of social anxiety in children and adolescents has produced highly inconsistent results which may partially be due to task differences and a limited breadth of autonomic measurement. Here we investigated a sample of high (HSA) and low socially anxious (LSA) children, aged ...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Schmitz J,Tuschen-Caffier B,Wilhelm FH,Blechert J

    更新日期:2013-10-01 00:00:00

  • Brain changes in early-onset bipolar and unipolar depressive disorders: a systematic review in children and adolescents.

    abstract::Pediatric bipolar disorder (BD) and unipolar disorder (UD) share common symptomatic and functional impairments. Various brain imaging techniques have been used to investigate the integrity of brain white matter (WM) and gray matter (GM) in these disorders. Despite promising preliminary findings, it is still unclear wh...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章,评审


    authors: Serafini G,Pompili M,Borgwardt S,Houenou J,Geoffroy PA,Jardri R,Girardi P,Amore M

    更新日期:2014-11-01 00:00:00

  • Juvenile firesetting in Italy: relationship to aggression, psychopathology, personality, self-efficacy, and school functioning.

    abstract::Despite the fact that juvenile fire involvement is associated with significant injuries and is highly correlated with diverse maladjustment characteristics, firesetting has never been empirically evaluated in Italy. Participants included 567 youth between 11 and 18 years of age. This investigation attempted to address...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Del Bove G,Caprara GV,Pastorelli C,Paciello M

    更新日期:2008-06-01 00:00:00

  • No evidence for association and linkage disequilibrium between dyslexia and markers of four dopamine-related genes.

    abstract::Dopamine genes are candidate genes for dyslexia in the light of the well-known comorbidity between dyslexia and ADHD. Within-family association and linkage disequilibrium were tested between four genetic markers at DRD4, DRD3, DRD2, and DAT loci, and dyslexia, in a sample of 130 Italian dyslexic children, 16.9% of who...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Marino C,Giorda R,Vanzin L,Molteni M,Lorusso ML,Nobile M,Baschirotto C,Alda M,Battaglia M

    更新日期:2003-08-01 00:00:00

  • Service-level variation, patient-level factors, and treatment outcome in those seen by child mental health services.

    abstract::Service comparison is a policy priority but is not without controversy. This paper aims to investigate the amount of service-level variation in outcomes in child mental health, whether it differed when examining outcomes unadjusted vs. adjusted for expected change over time, and which patient-level characteristics wer...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Edbrooke-Childs J,Macdougall A,Hayes D,Jacob J,Wolpert M,Deighton J

    更新日期:2017-06-01 00:00:00

  • Autistic spectrum disorders in childhood epilepsy surgery candidates.

    abstract::One third of children with autistic spectrum disorders (or pervasive developmental disorders) enter that state by regression from a more normal prior development at the onset of epilepsy or epileptiform abnormality in the electroencephalogram. In a very small proportion structural lesions of the temporal lobes are dis...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Taylor DC,Neville BG,Cross JH

    更新日期:1999-09-01 00:00:00

  • Pathological Internet use among European adolescents: psychopathology and self-destructive behaviours.

    abstract::Rising global rates of pathological Internet use (PIU) and related psychological impairments have gained considerable attention in recent years. In an effort to acquire evidence-based knowledge of this relationship, the main objective of this study was to investigate the association between PIU, psychopathology and se...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Kaess M,Durkee T,Brunner R,Carli V,Parzer P,Wasserman C,Sarchiapone M,Hoven C,Apter A,Balazs J,Balint M,Bobes J,Cohen R,Cosman D,Cotter P,Fischer G,Floderus B,Iosue M,Haring C,Kahn JP,Musa GJ,Nemes B,Postuvan

    更新日期:2014-11-01 00:00:00

  • Exploring mediating factors in the association between parental psychological distress and psychosocial maladjustment in adolescence.

    abstract::Parental psychopathology is associated with increased psychosocial maladjustment in adolescents. We examined, from a psychosocial perspective, the association between parental psychological distress and psychosocial maladjustment in adolescents and assessed the mediating role of psychosocial covariates. This is a cros...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Roustit C,Campoy E,Chaix B,Chauvin P

    更新日期:2010-07-01 00:00:00

  • Diagnostic stability in adolescent onset psychotic disorders.

    abstract::The purpose was to examine the long-term stability of a diagnosis of psychotic disorder in adolescence and to focus on diagnostic change over time. A total of 88 patients with a first episode of early onset psychosis (before 19 years) were followed up an average of 10.5 years (range 5.1-18.2) after admission. This rep...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Jarbin H,von Knorring AL

    更新日期:2003-01-01 00:00:00

  • Psychosocial conditions and suicidal behavior in pregnant teenagers : a case-control study in Brazil.

    abstract:OBJECTIVE:To compare the psychosocial profile and suicidal behavior of 110 pregnant teenagers (PT) with 110 non-pregnant teenagers (NPT). METHOD:Subjects were matched by age and residential district. The research instruments used were a structured clinical interview and a self-reporting questionnaire based on psychome...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Freitas GV,Cais CF,Stefanello S,Botega NJ

    更新日期:2008-09-01 00:00:00

  • Twelve-month service use, suicidality and mental health problems of European adolescents after a school-based screening for current suicidality.

    abstract::Suicide is one of the leading causes of death in adolescents and help-seeking behaviour for suicidal behaviour is low. School-based screenings can identify adolescents at risk for suicidal behaviour and might have the potential to facilitate service use and reduce suicidal behaviour. The aim of this study was to asses...

    journal_title:European child & adolescent psychiatry

    pub_type: 杂志文章


    authors: Kaess M,Schnyder N,Michel C,Brunner R,Carli V,Sarchiapone M,Hoven CW,Wasserman C,Apter A,Balazs J,Bobes J,Cosman D,Haring C,Kahn JP,Keeley H,Kereszteny A,Podlogar T,Postuvan V,Varnik A,Resch F,Wasserman D

    更新日期:2020-12-15 00:00:00