Abstract：
OBJECTIVE:To study and evaluate a sequential, extended embryo culture system. DESIGN:Prospective study. SETTING:University-affiliated IVF clinic. PATIENT(S):All couples who were treated between October 1997 and July 1998. INTERVENTION(S):A standard human tubal fluid plus 10% serum substitute supplement (SSS) culture medium was used. The embryos were transferred to extended culture medium (S2 or G2) on day 3. MAIN OUTCOME MEASURE(S):Blastocyst formation and implantation and pregnancy rates. RESULT(S):Forty percent of the 20 donated cryopreserved embryos progressed to the blastocyst stage by day 6. Clinically, 7 (5.6%) of the 125 cycles did not result in a transfer. Blastocyst formation rates ranged from 33%-63% in the five study groups. Implantation rates ranged from 15%-52% and pregnancy rates ranged from 37%-75%. CONCLUSION(S):Extended culture to day 5 or 6 results in acceptable blastocyst formation rates, implantation rates, and pregnancy rates.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Patton PE,Sadler-Fredd K,Burry KA,Gorrill MJ,Johnson A,Larson JM,Wolf DPdoi
10.1016/s0015-0282(99)00294-0keywords:
subject
Has Abstractpub_date
1999-09-01 00:00:00pages
418-22issue
3eissn
0015-0282issn
1556-5653pii
S0015-0282(99)00294-0journal_volume
72pub_type
杂志文章abstract：OBJECTIVE:To evaluate the expression pattern of Dazl (deleted in azoospermia-like) protein in the mouse preimplantation embryo. DESIGN:Experimental study. SETTING:Medical research laboratory in a university hospital. ANIMAL(S):Twenty female 28- to 35-day-old FVB mice. INTERVENTION(S):Embryo collection at 1.5, 2.5, ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.03.041
更新日期：2008-05-01 00:00:00
abstract：:Eighty-seven patients who underwent a late secretory phase endometrial biopsy while taking clomiphene citrate (CC) for ovulation induction were studied. Of the endometrial biopsies, 21 (24%) showed an endometrium greater than 2 days out of phase (OOP) with respect to the subsequent menstrual cycle. All 87 patients wer...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60726-4
更新日期：1989-06-01 00:00:00
abstract：OBJECTIVE:To investigate whether the antiprogestin RU486 acts primarily on the hypothalamus to delay the midcycle gonadotropin surge and thus gain insight into the site(s) of action of P in the control of ovulation. DESIGN:Prospective, crossover, single-blinded clinical study. SETTING:Outpatient clinic in an academic...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)56811-3
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:To assess the effects of age on the hormonal, metabolic, and ultrasonographic features of polycystic ovary syndrome (PCOS). DESIGN:Observational study. SETTING:University department of obstetrics and gynecology. PATIENT(S):Patients with PCOS (n = 1,212) and healthy women (n = 254). INTERVENTION(S):None. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.11.041
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:To summarize the available published randomized controlled trial data regarding timing of P supplementation during the luteal phase of patients undergoing assisted reproductive technology (ART). DESIGN:A systematic review. SETTING:Not applicable. PATIENT(S):Undergoing IVF. INTERVENTION(S):Different starti...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2014.12.125
更新日期：2015-04-01 00:00:00
abstract：:Our article endeavors to be both a review of the recent past and a preview of the future of reproductive surgery. By reflecting on the rate of technological advancement over the past decade, we attempt to predict the trajectory of the next. We also delve into the changing nature and practical challenges of the practic...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2019.06.034
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:To investigate the ability of N-formyl-methionyl-leucyl-phenylalanine (f-MLP), complement 5a (C5a), and nerve growth factor (NGF) to stimulate human spermatozoal reactive oxygen species generation in fertile and infertile patients. DESIGN:Prospective, controlled study measuring human spermatozoal reactive ox...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55874-9
更新日期：1993-04-01 00:00:00
abstract：OBJECTIVE:To determine if ultrastructural tissue trauma occurs in the junctional zone in uteri in adenomyosis. DESIGN:A case-control experimental study. SETTING:Endometriosis research center. PATIENT(S):Twelve uteri with adenomyosis, and 9 uteri without adenomyosis, were gained during laparoscopy-assisted vaginal hy...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.09.002
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:To describe the surgical and reproductive outcomes of early diffuse uterine leiomyomatosis with hysteroscopic myomectomy. DESIGN:Retrospective report. SETTING:University hospital. PATIENT(S):Five consecutive women of reproductive age with innumerable small-sized (0.5-3 cm) diffuse uterine myomas with profu...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.01.100
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVE:To report a dichorionic quadramniotic quadruple gestation with monochorionic triamniotic triplets after intracytoplasmic sperm injection (ICSI) treatment and transfer of two embryos. DESIGN:Case report. SETTING:Academic reproductive medicine center. PATIENT(S):A 28-year-old nulligravida who underwent first...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.08.022
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:To develop a baseline for projected studies of a rat endometriosis model. DESIGN:We investigated the effects of two macrophage-related growth factors, platelet-derived growth factor (PDGF) and transforming growth factor-beta (TGF-beta), on proliferation, in vitro differentiation, and protein secretion of ute...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between liver fat and in vivo insulin sensitivity, body composition, abdominal adiposity, and lipid metabolism in obese adolescent girls with polycystic ovary syndrome (PCOS). DESIGN:Cross-sectional case-control study. SETTING:Research center. PATIENT(S):Thirty Tanner stage ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.08.015
更新日期：2013-12-01 00:00:00
abstract：:A single injection of the luteinizing hormone (LH)-releasing hormone (LHRH) agonist [D-Ala6,des-Gly-NH2(10)]LHRH ethylamide to female rats on diestrus I produced a marked reduction in ovarian LH/human chorionic gonadotropin (hCG) and follicle-stimulating hormone (FSH) receptor levels, uterine weight, and plasma proges...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43524-7
更新日期：1978-09-01 00:00:00
abstract：OBJECTIVE:To investigate whether the insulin receptor substrate (IRS)-2 G1057D polymorphism is associated with the risk of endometriosis, and to evaluate potential correlation of IRS2 gene polymorphism with the stages of endometriosis. DESIGN:Case-control study. SETTING:Gynecology clinics in university hospital. PAT...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.09.023
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To study the changes in semen parameters, gonadotropic and sex hormones, and serum leptin in obese fertile and infertile oligozoospermic men. DESIGN:Prospective. SETTING:University hospital. PATIENT(S):Forty-two obese fertile and 80 obese infertile oligozoospermic men (body mass index [BMI] >30). INTERVEN...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.03.085
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:To report a successfully managed case of extensive intracranial sinus thrombosis that occurred during an IVF cycle, and to review the literature. DESIGN:Case report and review of literature. SETTING:University-affiliated teaching hospital. PATIENT(S):A 38-year-old nulliparous woman who developed severe ova...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.12.024
更新日期：2007-09-01 00:00:00
abstract：:Neutrophil migration did not change during normal menstrual cycles but was significantly reduced during controlled ovarian hyperstimulation (COH). Correlations between neutrophil migration and serum hormone concentrations could not be established. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.05.091
更新日期：2004-12-01 00:00:00
abstract：:Total effective estrogenicity of several human oral contraceptives was investigated through a method determining uterine weight in immature rats. The preparations, normally given to human females in tablet, form were Norinyl-1 (.05 mg mestranol, 1mg norethindrone), Norinyl-2 (.10 mg mestranol, 2 mg norethindrone), Ov...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)36671-7
更新日期：1968-05-01 00:00:00
abstract：:The first subsequent pregnancy rate in a group of women who accepted a variety of contraceptive methods after delivery and after therapeutic abortion is reviewed. Regardless of method chosen, 20 to 30% of postdelivery and 18 to 20% of postabortion patients were pregnant again after 1 year. In those patients who chose ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：OBJECTIVE:To test a sucrose-glycerol cryoprotectant for IUI-ready sperm preparation. DESIGN:Semen aliquots from normozoospermic donors either were subjected to conventional semen freezing (TES and Tris yolk buffer in 7.4% final glycerol) with post-thaw processing or were preprocessed and frozen in HEPES-buffered human...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)81491-4
更新日期：1997-07-01 00:00:00
abstract：:Halving the standard daily dose of triptorelin at the start of ovarian stimulation in down-regulated women stimulated with recombinant FSH is enough for pituitary suppression and was associated with higher LH serum concentrations in the follicular phase. However, this did not translate into higher serum concentrations...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2004.10.032
更新日期：2005-03-01 00:00:00
abstract：OBJECTIVE:To explore the long-term outcome of patients who began IVF treatment by considering not only treatment outcome in the center but also the parenthood project outcome after discontinuation of unsuccessful IVF. DESIGN:Retrospective cohort follow-up study. SETTING:Two French IVF centers. PATIENT(S):Seven hundr...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.05.067
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:To investigate whether interleukin-1beta (IL-1beta) and interleukin-1alpha (IL-1alpha) affect the implantation rate of patients undergoing IVF-ET. DESIGN:Follicular fluid and serum were obtained on the day of hCG administration, the day of oocyte retrieval, and the day of embryo transfer. SETTING:Cellular i...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(98)00243-x
更新日期：1998-09-01 00:00:00
abstract：OBJECTIVE:To compare two commonly used protocols (fresh vs. vitrified) used to transfer euploid blastocysts after IVF with preimplantation genetic screening. DESIGN:Randomized controlled trial. SETTING:Private assisted reproduction center. PATIENT(S):A total of 179 patients undergoing IVF treatment using preimplanta...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2016.12.022
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:To compare the pregnancy outcomes of twin pregnancies following early transvaginal multifetal pregnancy reduction (MPR) with nonreduced twin gestations. DESIGN:Prospective cohort study. SETTING:Two tertiary medical centers. PATIENT(S):A cohort of 77 multiple pregnancies after reduction to twins and 78 dich...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2014.01.032
更新日期：2014-05-01 00:00:00
abstract：:Twenty-four women who had undergone total salpingectomy due to ectopic pregnancy and who subsequently underwent a laparotomy for a second ectopic pregnancy in their opposite tube were treated by the author. Treatment consisted of linear salpingostomy (n = 20) and partial salpingectomy (n = 4). The intrauterine pregnan...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60025-0
更新日期：1988-07-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of dienogest on the expression of Toll-like receptor (TLR) 4 in human endometrial epithelial cells. DESIGN:Prospective basic research study. SETTING:Pharmaceutical research center. PATIENT(S):None. INTERVENTION(S):Not applicable. MAIN OUTCOME MEASURE(S):TLR4 in the immortalized ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.09.040
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the association of an activating single-nucleotide polymorphism (SNP) at position -71 of the promoter of 17beta-hydroxysteroid dehydrogenase type 5 gene (-71A/G HSD17B5 SNP) and polycystic ovary syndrome (PCOS) in a well characterized cohort of caucasian PCOS women with biochemical hyperandrogenem...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.06.016
更新日期：2009-08-01 00:00:00
abstract：:Under pressure from involved families and time limitations, Israeli judges tend to authorize postmortem sperm retrieval and freezing, even in unmarried men and in contradiction to current, albeit non-legally binding, guidelines of the Attorney General. Postmortem sperm retrieval in our institution (2003 to June 2009) ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.10.035
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:To report the results of 20 orthotopic retransplantations of cryopreserved ovarian tissue after cancer treatment. DESIGN:Retrospective analysis. SETTING:Tertiary gynecology department. PATIENT(S):Twenty patients with malignant disease: 11 with hematological malignancies (55%), four with breast cancer (20%)...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.10.045
更新日期：2015-02-01 00:00:00
