Listeria monocytogenes infection of Caco-2 human epithelial cells induces activation of transcription factor NF-kappa B/Rel-like DNA binding activities.

Abstract:

:The effect of Listeria monocytogenes infection on the cellular level of transcription factor NF-kappa B in the human epithelia-like cell line Caco-2 was investigated. Infection with L. monocytogenes or treatment with lipoteichoic acid induced the formation of three NF-kappa B-like DNA-protein complexes C1, C2, and C3, which were identified as containing either, RelA and p50, RelB and p50, or p50, respectively. NF-kappa B activation in L. monocytogenes-infected Caco-2 cells was distinct from NF-kappa B activation in infected P388D1 macrophages concerning the NF-kappa B complexes formed and the kinetics of the induction.

journal_name

FEMS Microbiol Lett

authors

Hauf N,Goebel W,Fiedler F,Kuhn M

doi

10.1111/j.1574-6968.1999.tb13766.x

keywords:

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

117-22

issue

1

eissn

0378-1097

issn

1574-6968

pii

S0378-1097(99)00345-6

journal_volume

178

pub_type

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