Abstract:
BACKGROUND:Since most of the children observed in our Centre present enuresis with voiding disturbance, we carried out a study where these patients were treated with the DDAVP + Oxybutinin association. METHODS:We have treated 89 children with enuresis and voiding disturbances (urge incontinence, voiding urgency, urinated > 7 times a day), administering a drugs combination of desmopressin (20 micrograms/daily) and oxybutinin (0.3-0.6 mg/kg/bid or tid) for a variable period, depending on response to the treatment. RESULTS:The results demonstrate the efficacy of this association: we have observed a reduction in average bed wetting nights from 23.4 nights/month to 6.4 wet nights after 1 month, to 3.8 ad 2.9 respectively after 3 and 6 months from the beginning. Moreover we obtained a recovery of all daily voiding disturbances after 3 months. Fifty percent of children were cured after 4 months of therapy and finally 93.2% recovered at 6 months. On the other hand, 2 children were no-responders to the therapy even after 9 months of combined drugs administration. CONCLUSIONS:Based on these results we can affirm that children with nocturnal enuresis and voiding disturbance can be treated with this combined therapy. Actually, the reduction of urinary output and thus lower bladder filling, due to the desmopressin, decreases the onset of uninhibited bladder contractions and enhances oxybutinin activity.
journal_name
Minerva Pediatrjournal_title
Minerva pediatricaauthors
De Grazia E,Cimador Mkeywords:
subject
Has Abstractpub_date
1999-05-01 00:00:00pages
149-52issue
5eissn
0026-4946issn
1827-1715journal_volume
51pub_type
杂志文章abstract::The case of a six-year-old girl suffering from recurrent abdominal pain is reported. On the basis of the laboratory tests and a number of other clinical investigations, the diagnosis of ascaridiasis was made. At scanning electron microscopy the ultrastructural study of the bioptic fragments obtained during endoscopy s...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract::Megapolycalicosis is defined as a congenital dilatation of calices without evidence of obstruction. In absence of complications such as infection and stones, megapolycalicosis would not have a particular clinical relevance if not for the possible misinterpretation as hydronephrosis. A case of megapolycalicosis is pres...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::The care of adolescents suffering from high risk disease is a demanding challenge. At times, adolescents may well be too old for the pediatrician and Pediatric Units, and yet too young for the adult practitioner. A dedicated approach that builds on the insight deriving from special attention to, and reflection on the ...
journal_title:Minerva pediatrica
pub_type: 社论
doi:
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:A drug-related problem (DRP) may be defined as "an event or circumstance involving drug therapy that actually or potentially interferes with the desired health outcome". Our aim was to determine the frequency and characteristics of DRPs in pediatric patients admitted to a tertiary cardiac care center in the ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2016-04-01 00:00:00
abstract:AIM:Myelomeningocele (MMC), among others functions, affects colorectal motility and bowel emptying, and often leads to constipation, faecal incontinence, or a combination of both. We investigated the benefits of transanal irrigation (TI) in children with MMC through the radiological study of intestinal transit time. M...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:To investigate if high dose inhaled beclomethasone dipropionate started early after upper respiratory tract infection (URTI) could reduce recurrent wheezing in infants. METHODS:Twenty-six ambulatory infants, 7-12 months of age, with recurrent wheezing during upper respiratory tract infection participated. A...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND AND AIMS:The hypothesis of an emotional component in asthma has been put forward since antiquity. It is currently explored using a psychodynamic, cognitive-behavioural and systemic-relational approach. This study, carried out using a psychodynamic approach, aimed to identify the psychological aspects of recu...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Recently it is often very frequent a request of specialist consultation for children with psychic discomfort expressed through somatic complaints and/or behavior disorders. The real meaning of these symptoms in terms of prognosis, is not clear; indeed they can be the first signs of a poor prognosis of develo...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1998-09-01 00:00:00
abstract::Cystic fibrosis (CF) is a genetic disease associated with recurrent lung infections, that represent a major cause of mortality and morbidity. Cystic fibrosis requires frequent antibiotic treatments, sometimes by mouth or via aerosol but often via the intravenous route. Totally implanted venous access devices (ports) a...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2009-10-01 00:00:00
abstract:AIM:The median urinary iodine concentration (UIC) for schoolchildren was 90 microg/L in Biella and 136 microg/L in Novara in survey carried out in 1995-1996. Biella resulted as iodine deficiency area and Novara as iodine sufficient area. Aim of our study was to assess goiter prevalence by ultrasonography in Biella and ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:The aim of the present study is to investigate the suicide and attempted suicide phenomenon among young people (<25 years old) in the Verbano-Cusio-Ossola province from January 1988 to December 2000. METHODS:This epidemiological-descriptive survey is based on the acquisition of data through the examination ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract::To establish the effectiveness of flunisolide + salbutamol vs salbutamol alone administered by metered aerosol in the phlogistic obstructive diseases, 18 children were evaluated. The treatments were evaluated on the basis of ventilatory function parameters and of tolerance. The results proved positive for all drugs, t...
journal_title:Minerva pediatrica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-06-01 00:00:00
abstract::Intracranial tuberculoma is a possible complication of meningeal, miliary or pulmonary tuberculosis. In developing countries it represents 30% of space-occupying intracranial lesions, in industrialised countries only 0.1-0.2%. One recently recognised phenomenon is the development ex novo or the enlargement of the tube...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Specific learning disabilities are disorders that affect the instrumental skills of academic learning, leaving intact the general intellectual functioning. It is possible to distinguish: dyslexia, dysorthography, dysgraphia, and dyscalculia. The diagnosis is made according to DSMV. The aim of this study is t...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.18.05036-3
更新日期:2018-04-12 00:00:00
abstract:INTRODUCTION:At present, morphine is the most commonly used first-line therapy to treat Neonatal Abstinence Syndrome (NAS). Unfortunately, there is still lack of evidence and consensus to guide pharmacologic therapy for NAS. In this review, we provide an overview on dosing regimens of morphine currently reported to tre...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4946.17.04928-3
更新日期:2019-06-01 00:00:00
abstract::The nailfold capillaroscopy allows to study the microcirculation: for its simple and rapid execution it can be used also in children. We examined the nailfold capillaroscopy features in childhood and valued the maturation of microcirculation in connection to age and presented some pathologic patterns. We studied nailf...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract::The dominant cause of mortality, morbidity and hospitalization worldwide is cardiac complications, and are the major public health problem in adult populations. The worldwide research is being focused on the idea that cardiovascular disease is an early life pathological state. Early unfavorable exposures, acting in di...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4946.16.04713-7
更新日期:2017-06-01 00:00:00
abstract::Hyperinsulinism is an important cause of hypoglycemia in early infancy. Many forms of hyperinsulinemic hypoglycemia are described: transient, prolonged, persistent. Transient forms are well recognized in infants of diabetic mother; prolonged forms are responsible for the hypoglycemia in small-for-date (SGA) infants an...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
abstract::Personal experience of a series of mycoplasma-induced pneumoniae is reported. The importance of early diagnosis for the purpose of speedy target antibiotic therapy is reiterated. Stress is laid on the absence of complications in all patients studied. ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract:BACKGROUND:COVID-19 has quickly become a worldwide threat to health, travel, and commerce. Studies adressing the clinical-functional presentation of viral infection and physiotherapy management in children are scarce. The purpose statement was to provide current perspectives on the physiotherapy interventions for manag...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.20.06100-9
更新日期:2020-10-27 00:00:00
abstract::Nasal decongestants are widely used in the treatment of rhinitis. Decongestant drugs are one of the main components, but numerous reports gave been made concerning side, local and general effects. The problem is particularly important in the treatment of infantile rhinitis for which the use of saline solution alone is...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::We report a case of esophageal achalasia in a nine months old baby. Recurrent cough and cyanosis were the most important clinical findings. Esophagomyotomy remarkably improved the clinical symptoms. Disorders of esophageal motility may be an important cause of respiratory emergencies in the first year of life. ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:The nutritional status of foster children, the quality of daily menus in group homes and the food security inside these organizations have been poorly studied. For this reason, the aim of this study was to investigate them. METHODS:A sample of 125 children, ranging in age from 0-17 years, among seven group ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04802-7
更新日期:2020-12-01 00:00:00
abstract::In 1967 a baby was observed who presented post-natal progressive growth deficit, mental retardation, craniofacial dysmorphias and other malformations which didn't form part of the syndromes till then known. However the first description of patients with this combination of anomalies dates back to 1981, when Niikawa an...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:1999-07-01 00:00:00
abstract::Some reports have been published concerning the positive effects of using intravenous immunoglobulins as immunotherapy and immunoprophylaxis of infection in newborns. The safety and efficacy of intravenously administered gamma globulins 7S versus 5S was evaluated in 64 high-risk neonates. The infants admitted to this ...
journal_title:Minerva pediatrica
pub_type: 临床试验,杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:YouTube is overloaded with various medical videos and has become a common source for surgeons and the general public alike to update on surgical procedures. This study determined the quality and benefits of information with regards to laparoscopic pyloromyotomy on YouTube. METHODS:A search was performed on ...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.18.05178-2
更新日期:2018-07-18 00:00:00
abstract:BACKGROUND:Neonatal morbidity and mortality differ between very preterm infants that result from single and those that result from a multiple order pregnancy. The aim of our study was to assess and compare the neonatal morbidity and mortality of multiple versus single very preterm infants. METHODS:Obstetrical and neon...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.19.05592-0
更新日期:2019-11-05 00:00:00
abstract::GER is the passage of gastric contents into the esophagus and is referred to as GER disease (GERD) when GER causes troublesome symptoms and/or complications. GERD in infants and children is sometimes difficult to diagnose and even more difficult to treat. The diagnosis of GERD is hampered by the fact that GER symptoms...
journal_title:Minerva pediatrica
pub_type: 杂志文章,评审
doi:
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:The aim of our study was multifaceted neurodevelopmental examination of children born prematurely with very low birth weight (VLBW) in order to evaluate the usefulness of popularly used tests. The second aim of the study was exploration of risk and protective factors of neurodevelopmental impairment. METHOD...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04513-8
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine serum pancreatic stone protein (PSP) levels in the neonates with highly probable or probable sepsis and assess their possible value in predicting infected neonates. METHODS:This was a prospective study involving 119 neonates who were admitted with suspected sepsis. The...
journal_title:Minerva pediatrica
pub_type: 杂志文章
doi:10.23736/S0026-4946.16.04317-X
更新日期:2017-12-01 00:00:00