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Radiographic assessment of osteoarthritis: comparison between existing methodologies.

Abstract：

:Radiographic sensitivity for quantifying the rate of change in joint space width (JSW) for DMOAD trials, is influenced by the following, which vary between methodologies for imaging hip, knee and hand. Radio-anatomical plane of measurement JSW measurement precision is improve when the (i) joint is in a normal functional position, (ii) X-ray beam is centred on the joint space and (iii) plane of measurement is orthogonal to the beam and articular surfaces, and parallel to the film. Measuring instrument Manual methods, e.g. callipers with graduated magnifying lens or digitisation tablets, suffer from observer variability but are practical and can reliably measure JSW. Computer-based techniques provide precise and accurate JSW measurements. Site of measurement Minimum JSW may lie within the joint's load transmitting region. JSW area and mean area assess the entire JS width. Radiographic magnification This effect is present in hip and knee radiographs and when not corrected, requires increased study numbers. Type of X-ray unit Microfocal radiography's improved spatial resolution increases measurement precision and can decrease study numbers.

journal_name

Osteoarthritis Cartilage

journal_title

Osteoarthritis and cartilage

authors

Buckland-Wright

doi

10.1053/joca.1998.0234

keywords:

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

430-3

issue

4

eissn

1063-4584

issn

1522-9653

pii

S1063458498902345

journal_volume

7

pub_type

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