The relation of femoral notch stenosis to ACL tears in persons with knee osteoarthritis.

Abstract:

OBJECTIVE:A significant risk factor for anterior cruciate ligament (ACL) tears in young athletes is a reduced femoral Notch Width Index (NWI). The purpose of this study was to test if persons with knee osteoarthritis (OA) and ACL tears have smaller NWI independent of prior joint injury and osteophyte volume. METHODS:We included 160 participants from the progression sub-cohort of the Osteoarthritis Initiative (OAI) Study, an ongoing 4-year, multi-center study, focusing on knee OA. The femoral notch width, the condylar notch width at 2/3 of the notch depth, and the intercondylar notch angle (beta) were measured on sagittal and coronal MR-images. NWI=notch width/condylar width at 2/3 of the notch depth, was calculated and outcome of ACL tear frequency was compared between two groups; NWI0.20. The NWI and beta were analyzed as continuous variables. RESULTS:Of the 160 subjects [51% female, age 62.1 (+/-9.9), BMI 30.3 (+/-4.7)kg/m(2)] 14.4% showed an ACL tear. Osteophyte bone volume was available for 150 participants, of which 13% had an ACL tear. The continuous measure of NWI on the coronal images was significantly (P=0.01) smaller in participants with ACL tear [0.246, 95% confidence interval (CI) 0.234-0.258] compared to those without (0.263, 95% CI 0.258-0.268). Adjustment for demographic variables still showed significant results (P=0.03, mean difference 0.015 95% CI -0.001-0.030) and adjustment for demographic variables and osteophyte bone volume were borderline significant (P=0.06, mean difference 0.015 95% CI 0.001-0.029). CONCLUSIONS:We identified a smaller NWI in participants with knee OA and ACL tears. Further longitudinal investigation is necessary to determine this as an independent risk factor.

authors

Stein V,Li L,Guermazi A,Zhang Y,Kent Kwoh C,Eaton CB,Hunter DJ,OAI Investigators.

doi

10.1016/j.joca.2009.09.006

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

192-9

issue

2

eissn

1063-4584

issn

1522-9653

pii

S1063-4584(09)00247-7

journal_volume

18

pub_type

杂志文章,多中心研究
  • Should subchondral bone turnover be targeted when treating osteoarthritis?

    abstract:OBJECTIVE:Osteoarthritis (OA) is the most common form of arthritic disease, and it is a major cause of disability and impaired quality of life in the elderly. OA is a complex disease of the entire joint, including bone and cartilage, thereby presenting alternative approaches for treatment. This review summarizes emergi...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章,评审

    doi:10.1016/j.joca.2008.01.014

    authors: Karsdal MA,Leeming DJ,Dam EB,Henriksen K,Alexandersen P,Pastoureau P,Altman RD,Christiansen C

    更新日期:2008-06-01 00:00:00

  • Osteoarthritis year in review 2019: imaging.

    abstract:OBJECTIVE:To provide a narrative review of original articles on osteoarthritis (OA) imaging published between April 1, 2018 and March 30, 2019. METHODS:All original research articles on OA imaging published in English between April 1, 2018 and March 30, 2019 were identified using a PubMed database search. The search t...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章,评审

    doi:10.1016/j.joca.2019.11.009

    authors: Kijowski R,Demehri S,Roemer F,Guermazi A

    更新日期:2020-03-01 00:00:00

  • A randomized trial of patellofemoral bracing for treatment of patellofemoral osteoarthritis.

    abstract:PURPOSE:The number of effective knee osteoarthritis (OA) interventions, especially those tailored to specific compartmental involvement, are small. The objective of this study was to determine the efficacy of a realigning patellofemoral (PF) brace in improving pain and function among persons with symptomatic lateral PF...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.joca.2010.12.010

    authors: Hunter DJ,Harvey W,Gross KD,Felson D,McCree P,Li L,Hirko K,Zhang B,Bennell K

    更新日期:2011-07-01 00:00:00

  • Associations among preoperative MRI features and functional status following arthroscopic partial meniscectomy.

    abstract:BACKGROUND:Arthroscopic partial meniscectomy (APM) is the most frequently performed orthopedic procedure. Functional outcomes of APM are variable, particularly among patients with underlying knee osteoarthritis. While most patients undergoing APM have knee magnetic resonance imaging (MRI) performed preoperatively, the ...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2005.11.014

    authors: Katz JN,Meredith DS,Lang P,Creel AH,Yoshioka H,Neumann G,Fossel AH,de Pablo P,Losina E

    更新日期:2006-05-01 00:00:00

  • Characterization of infiltrating T cells and Th1/Th2-type cytokines in the synovium of patients with osteoarthritis.

    abstract:OBJECTIVE:It has been suggested that osteoarthritis (OA) is induced by mechanical stress followed by cartilage destruction, and it is generally accepted that there is little involvement of an immune response in OA compared with that in rheumatoid arthritis (RA). We have previously found clonally expanded transcripts of...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1053/joca.2001.0509

    authors: Ishii H,Tanaka H,Katoh K,Nakamura H,Nagashima M,Yoshino S

    更新日期:2002-04-01 00:00:00

  • Sedentary behavior and blood pressure control among osteoarthritis initiative participants.

    abstract:OBJECTIVE:To examine the association between sedentary behavior and blood pressure (BP) among Osteoarthritis Initiative (OAI) participants. DESIGN:We conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into ...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.joca.2014.07.007

    authors: Sohn MW,Manheim LM,Chang RW,Greenland P,Hochberg MC,Nevitt MC,Semanik PA,Dunlop DD

    更新日期:2014-09-01 00:00:00

  • Morphological changes of the lateral meniscus in end-stage lateral compartment osteoarthritis of the knee.

    abstract:OBJECTIVE:The aim of this study was to evaluate the morphological changes of the lateral meniscus in end-stage lateral compartment osteoarthritis (OA) of the knee. METHODS:One hundred fifty-eight knee joints from 133 patients that subsequently underwent total knee joint arthroplasty from January 2008 to December 2009 ...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2011.11.005

    authors: Hwang SH,Jung KA,Lee WJ,Yang KH,Lee DW,Carter A,Park CH,Hunter DJ

    更新日期:2012-02-01 00:00:00

  • Increased serum levels of non-collagenous matrix proteins (cartilage oligomeric matrix protein and melanoma inhibitory activity) in marathon runners.

    abstract:OBJECTIVE:Marathon runners have an increased risk of developing joint disease. During and after a 42-km run, elevation of multiple cytokines occurs in the blood, reflecting inflammatory processes. We compared this cytokine response with serum levels of cartilage oligomeric matrix protein (COMP) and melanoma inhibitory ...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1053/joca.1999.0293

    authors: Neidhart M,Müller-Ladner U,Frey W,Bosserhoff AK,Colombani PC,Frey-Rindova P,Hummel KM,Gay RE,Häuselmann H,Gay S

    更新日期:2000-05-01 00:00:00

  • Femoral trabecular bone of osteoarthritic and normal subjects in an age and sex matched group.

    abstract:OBJECTIVE:To describe changes to the cancellous structure of femoral bone from patients with severe primary osteoarthritis by comparison with age and sex matched controls. METHOD:Specimens were taken from 18 male and 18 female pairs. One of each pair was a normal control, the other having severe primary osteoarthritis...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1053/joca.1998.0141

    authors: Fazzalari NL,Parkinson IH

    更新日期:1998-11-01 00:00:00

  • The association between reduced knee joint proprioception and medial meniscal abnormalities using MRI in knee osteoarthritis: results from the Amsterdam osteoarthritis cohort.

    abstract:BACKGROUND:Osteoarthritis (OA) of the knee is characterized by pain and activity limitations. In knee OA, proprioceptive accuracy is reduced and might be associated with pain and activity limitations. Although causes of reduced proprioceptive accuracy are divergent, medial meniscal abnormalities, which are highly preva...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2013.02.002

    authors: van der Esch M,Knoop J,Hunter DJ,Klein JP,van der Leeden M,Knol DL,Reiding D,Voorneman RE,Gerritsen M,Roorda LD,Lems WF,Dekker J

    更新日期:2013-05-01 00:00:00

  • Synovial incorporation of polyacrylamide hydrogel after injection into normal and osteoarthritic animal joints.

    abstract:OBJECTIVE:Polyacrylamide hydrogel (PAAG) is a non-toxic, non-degradable synthetic product, used for years in the augmentation of soft tissues. Preliminary results in animals and humans have suggested long-lasting beneficial effects on symptoms of osteoarthritis (OA). The aim of this histopathological study was to inves...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2016.07.007

    authors: Christensen L,Camitz L,Illigen KE,Hansen M,Sarvaa R,Conaghan PG

    更新日期:2016-11-01 00:00:00

  • Efficacy of intraarticular hyaluronic acid in patients with osteoarthritis--a prospective clinical trial.

    abstract:AIM:The goal of this study was to determine whether or not the intraarticular administration of hyaluronic acid can improve functional parameters, such as isokinetic muscle strength or total work and clinical test results in patients with osteoarthritis (OA) of the knee. METHOD:As part of a prospective, controlled stu...

    journal_title:Osteoarthritis and cartilage

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1053/joca.2002.0815

    authors: Miltner O,Schneider U,Siebert CH,Niedhart C,Niethard FU

    更新日期:2002-09-01 00:00:00

  • Pain, motor and gait assessment of murine osteoarthritis in a cruciate ligament transection model.

    abstract:OBJECTIVE:The major complaint of Osteoarthritis (OA) patients is pain. However, due to the nature of clinical studies and the limitation of animal studies, few studies have linked function impairment and behavioral changes in OA animal models to cartilage loss and histopathology. Our objective was to study surrogate ma...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2013.06.016

    authors: Ruan MZ,Patel RM,Dawson BC,Jiang MM,Lee BH

    更新日期:2013-09-01 00:00:00

  • Long-term periarticular bone adaptation in a feline knee injury model for post-traumatic experimental osteoarthritis.

    abstract:OBJECTIVES:This study investigates the long-term changes of the periarticular bone, including cancellous bone and the subchondral plate, in an anterior cruciate ligament (ACL)-transected cat for post-traumatic osteoarthritis (OA). These periarticular bone changes are related to the health of all knee tissues including ...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2004.11.004

    authors: Boyd SK,Müller R,Leonard T,Herzog W

    更新日期:2005-03-01 00:00:00

  • Establishment of a bipotent cell line CL-1 which differentiates into chondrocytes and adipocytes from adult mouse.

    abstract:OBJECTIVE:Establishment of a clonal bipotent chondroprogenitor cell line from adult mouse to provide a new tool for the elucidation of chondrogenesis in adult animal. DESIGN:A clonal cell line CL-1 was established from tibia of adult mouse. Differentiation of CL-1 was characterized in monolayer culture. Effects of gro...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2003.09.002

    authors: Kitamura H

    更新日期:2004-01-01 00:00:00

  • 2D and 3D MOCART scoring systems assessed by 9.4 T high-field MRI correlate with elementary and complex histological scoring systems in a translational model of osteochondral repair.

    abstract:OBJECTIVE:To compare the 2D and 3D MOCART system obtained with 9.4 T high-field magnetic resonance imaging (MRI) for the ex vivo analysis of osteochondral repair in a translational model and to correlate the data with semiquantitative histological analysis. METHODS:Osteochondral samples representing all levels of repa...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2014.05.027

    authors: Goebel L,Zurakowski D,Müller A,Pape D,Cucchiarini M,Madry H

    更新日期:2014-10-01 00:00:00

  • Dynamic knee loading is related to cartilage defects and tibial plateau bone area in medial knee osteoarthritis.

    abstract:OBJECTIVE:To evaluate the relationship between dynamic mechanical loading, as indicated by external knee adduction moment (KAM) measures during walking, and measures of articular cartilage morphology and subchondral bone size in people with medial knee osteoarthritis (OA). DESIGN:180 individuals with radiographic medi...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2010.08.013

    authors: Creaby MW,Wang Y,Bennell KL,Hinman RS,Metcalf BR,Bowles KA,Cicuttini FM

    更新日期:2010-11-01 00:00:00

  • Associations between pre-operative radiographic changes and outcomes after total knee joint replacement for osteoarthritis.

    abstract:OBJECTIVE:To assess the influence of pre-operative X-ray changes on the response to total knee joint replacement (TKR). METHODS:We included patients from one centre who underwent primary TKR (n = 478) for osteoarthritis in 2006 and 2007. The International Knee Society score (IKSS) and short form health survey were col...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2012.05.015

    authors: Dowsey MM,Nikpour M,Dieppe P,Choong PF

    更新日期:2012-10-01 00:00:00

  • Test-retest reliability and responsiveness of centre of pressure measurements in patients with hip osteoarthritis.

    abstract:OBJECTIVE:The aim of this study was to determine a set of measures for the evaluation of balance in patients suffering from hip osteoarthritis (OA) that were both reliable and responsive to change. DESIGN:Three groups of subjects; Healthy, hip OA patients without surgery, and hip OA with surgery (pre and post-surgery)...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2015.03.029

    authors: Laroche D,Kubicki A,Stapley PJ,Gremeaux V,Mazalovic K,Maillefert JF,Ornetti P

    更新日期:2015-08-01 00:00:00

  • Evidence that meniscus damage may be a component of osteoarthritis: the Framingham study.

    abstract:OBJECTIVES:The etiology of degenerative meniscus tear is unclear but could be related to a generalized osteoarthritic disease process. We studied whether radiographic hand osteoarthritis (OA) is associated with meniscus damage. METHODS:We examined 974 persons aged 50-90 years drawn via census tract data and random-dig...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2015.08.005

    authors: Englund M,Haugen IK,Guermazi A,Roemer FW,Niu J,Neogi T,Aliabadi P,Felson DT

    更新日期:2016-02-01 00:00:00

  • Qualitative and quantitative assessment of cartilage degeneration using full-field optical coherence tomography ex vivo.

    abstract:OBJECTIVE:The purpose of this study was to investigate the ability of full-field optical coherence tomography (FFOCT) to qualitatively and quantitatively evaluate cartilage degeneration using the qualitative evaluation of histology sections as the reference. DESIGN:Thirty-three human knee cartilage samples of variable...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2017.11.008

    authors: Pailhé R,Mounier A,Boisson B,Rouchy RC,Voros S,Chipon E,Boudry I,Medici M,Hughes C,Moreau-Gaudry A

    更新日期:2018-02-01 00:00:00

  • The chemokine receptor CCR5 plays a role in post-traumatic cartilage loss in mice, but does not affect synovium and bone.

    abstract:OBJECTIVE:C-C chemokine receptor type 5 (CCR5) has been implicated in rheumatoid arthritis and several inflammatory diseases, where its blockade resulted in reduced joint destruction. However, its role in modulating cartilage and bone changes in post-traumatic osteoarthritis (OA) has not yet been investigated. In this ...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2014.12.002

    authors: Takebe K,Rai MF,Schmidt EJ,Sandell LJ

    更新日期:2015-03-01 00:00:00

  • Forecasting the future burden of opioids for osteoarthritis.

    abstract:OBJECTIVE:To quantify the current national burden of opioids for osteoarthritis (OA) pain in Australia in terms of number of dispensed opioid prescriptions and associated costs, and to forecast the likely burden to the year 2030/31. DESIGN:Epidemiological modelling. METHODS:Published data were obtained on rates of op...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2017.11.001

    authors: Ackerman IN,Zomer E,Gilmartin-Thomas JF,Liew D

    更新日期:2018-03-01 00:00:00

  • MicroRNAs: exploring new horizons in osteoarthritis.

    abstract:INTRODUCTION:Osteoarthritis (OA) is a common disease worldwide leading to significant morbidity. The underlying disease process is multifactorial however there is increasing focus on molecular mechanisms. MicroRNAs are small non-coding segments of RNA that have important regulatory functions at a cellular level. These ...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章,评审

    doi:10.1016/j.joca.2015.10.018

    authors: Nugent M

    更新日期:2016-04-01 00:00:00

  • Poor replicability of recommended exercise interventions for knee osteoarthritis: a descriptive analysis of evidence informing current guidelines and recommendations.

    abstract:OBJECTIVE:To examine the reporting completeness of exercise-based interventions for knee osteoarthritis (OA) in studies that form the basis of current clinical guidelines, and examine if the clinical benefit (pain and disability) from exercise is associated with the intervention reporting completeness. DESIGN:Review o...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.joca.2018.06.018

    authors: Bartholdy C,Nielsen SM,Warming S,Hunter DJ,Christensen R,Henriksen M

    更新日期:2019-01-01 00:00:00

  • External knee adduction and flexion moments during gait and medial tibiofemoral disease progression in knee osteoarthritis.

    abstract:OBJECTIVE:Test the hypothesis that greater baseline peak external knee adduction moment (KAM), KAM impulse, and peak external knee flexion moment (KFM) during the stance phase of gait are associated with baseline-to-2-year medial tibiofemoral cartilage damage and bone marrow lesion progression, and cartilage thickness ...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2015.02.005

    authors: Chang AH,Moisio KC,Chmiel JS,Eckstein F,Guermazi A,Prasad PV,Zhang Y,Almagor O,Belisle L,Hayes K,Sharma L

    更新日期:2015-07-01 00:00:00

  • The relationship between specific tissue lesions and pain severity in persons with knee osteoarthritis.

    abstract:INTRODUCTION:Pain is the most common symptom in knee osteoarthritis (OA), a leading cause of chronic disability, and a major source of the disability attributable to OA in general. Pain severity in knee OA is variable, ranging from barely perceptible to immobilizing. The knee lesions that contribute to pain severity ha...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1016/j.joca.2006.03.015

    authors: Torres L,Dunlop DD,Peterfy C,Guermazi A,Prasad P,Hayes KW,Song J,Cahue S,Chang A,Marshall M,Sharma L

    更新日期:2006-10-01 00:00:00

  • Human chondrocyte apoptosis in response to mechanical injury.

    abstract:OBJECTIVE:The effect of mechanical injury on chondrocyte viability and matrix degradation was studied. It was proposed that mechanical injury to human cartilage explants results in chondrocyte apoptosis with associated loss of glycosaminoglycans. DESIGN:Full thickness human cartilage explants, 5 mm in diameter were su...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1053/joca.2001.0468

    authors: D'Lima DD,Hashimoto S,Chen PC,Colwell CW Jr,Lotz MK

    更新日期:2001-11-01 00:00:00

  • Osteoarthritis biomarkers: year in review.

    abstract:OBJECTIVE:To summarise important findings from biomarker studies relevant to osteoarthritis (OA), published between April 2016 and March 2017; to consider these findings in the context of new discoveries and technologies, and clinical and scientific need in OA. DESIGN:Studies were selected by PubMed search, conducted ...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章,评审

    doi:10.1016/j.joca.2017.10.016

    authors: Watt FE

    更新日期:2018-03-01 00:00:00

  • Dimensionality and clinical importance of pain and disability in hand osteoarthritis: Development of the Australian/Canadian (AUSCAN) Osteoarthritis Hand Index.

    abstract:OBJECTIVE:To develop a reliable, valid, and responsive self-administered questionnaire to probe pain, stiffness and physical disability in patients with osteoarthritis (OA) of the hand. DESIGN:In order to assess the dimensionality of the symptomatology of hand OA, a self-administered questionnaire was developed to pro...

    journal_title:Osteoarthritis and cartilage

    pub_type: 杂志文章

    doi:10.1053/joca.2002.0837

    authors: Bellamy N,Campbell J,Haraoui B,Buchbinder R,Hobby K,Roth JH,MacDermid JC

    更新日期:2002-11-01 00:00:00