Involvement of T3Ralpha- and beta-receptor subtypes in mediation of T3 functions during postnatal murine intestinal development.

abstract：BACKGROUND & AIMS:The metaplastic process in which the normal squamous epithelium of the distal esophagus is replaced by columnar-lined epithelium, known as Barrett's esophagus (BE), is poorly understood. The aim of this study was to define, analyze, and compare transcription profiles of BE, normal cardia epithelium, a...

journal_title：Gastroenterology

authors： van Baal JW,Milano F,Rygiel AM,Bergman JJ,Rosmolen WD,van Deventer SJ,Wang KK,Peppelenbosch MP,Krishnadath KK

更新日期：2005-10-01 00:00:00

abstract：:Vascular casts of human oxyntic mucosa, examined by scanning electron microscopy, revealed that (a) arterial breakup occurs only at the submucosal aspect of the mucosa, there being no arterial vessels further into the mucosa and (b) mucosal capillaries drain into the infrequent mucosal venules only in the most luminal...

journal_title：Gastroenterology

authors： Gannon B,Browning J,O'Brien P,Rogers P

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND & AIMS:Infliximab is effective in closing fistulas in patients with Crohn's disease. We examined the effect of infliximab maintenance treatment on hospitalizations, surgeries, and procedures in patients with fistulizing Crohn's disease enrolled in the ACCENT II study. METHODS:After 5 mg/kg infliximab at wee...

journal_title：Gastroenterology

authors： Lichtenstein GR,Yan S,Bala M,Blank M,Sands BE

更新日期：2005-04-01 00:00:00

abstract：:Because approximately 80% of reported patients with somatostatinomas have gallstones, this study was performed to determine the effects of exogenous somatostatin on gallbladder emptying responses to liquid and solid meals, direct cholinergic stimulation by bethanechol, indirect cholinergic stimulation by sham feeding,...

journal_title：Gastroenterology

authors： Fisher RS,Rock E,Levin G,Malmud L

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND & AIMS:The aim of this study was to generate an improved prognostic model for predicting recurrence in liver transplant candidates with hepatocellular carcinoma (HCC). METHODS:Predictors of recurrence were tested by a Cox model analysis in a training cohort of 537 patients transplanted for HCC. A prognostic...

journal_title：Gastroenterology

authors： Duvoux C,Roudot-Thoraval F,Decaens T,Pessione F,Badran H,Piardi T,Francoz C,Compagnon P,Vanlemmens C,Dumortier J,Dharancy S,Gugenheim J,Bernard PH,Adam R,Radenne S,Muscari F,Conti F,Hardwigsen J,Pageaux GP,Chazouill

更新日期：2012-10-01 00:00:00

abstract：:A case of enterogenous cysts of the duodenum in a 44-yr-old man complicated by duodenal obstruction and relapsing pancreatitis is presented. The cystic duodenal lesions were visualized by endoscopic retrograde cholangiopancreatography and for the first time by computed tomography and abdominal sonography. Thus, the di...

journal_title：Gastroenterology

authors： Holstege A,Barner S,Brambs HJ,Wenz W,Gerok W,Farthmann EH

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Capsaicin-sensitive neurons contain various peptides including calcitonin gene-related peptide. This study examines (1) whether calcitonin gene-related peptide is involved in capsaicin-induced gastroprotection and (2) whether nitric oxide and prostaglandin are required for calcitonin gene-related peptide to ...

journal_title：Gastroenterology

authors： Lambrecht N,Burchert M,Respondek M,Müller KM,Peskar BM

更新日期：1993-05-01 00:00:00

abstract：:Diverting the fecal stream has been considered to affect the course of Crohn's disease favorably. Adverse effects on the distal segment have not previously been distinguished from clinical signs and symptoms. The course of four patients with Crohn's disease who underwent fecal diversion with an in situ rectum were obs...

journal_title：Gastroenterology

authors： Korelitz BI,Cheskin LJ,Sohn N,Sommers SC

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND & AIMS:The effects of leukotriene (LT) D(4) on intestinal epithelial cells govern events that are involved in cell survival and colon cancer, notably increased expression of cyclooxygenase (COX)-2 and enhanced production of prostaglandin E(2). We investigated possible correlations between distribution of the...

journal_title：Gastroenterology

authors： Ohd JF,Nielsen CK,Campbell J,Landberg G,Löfberg H,Sjölander A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND & AIMS:Two percent to 4% of all cases of colorectal cancer (CRC) are associated with Lynch syndrome. Dominant clustering of CRC (non-Lynch syndrome) accounts for 1%-3% of the cases. Because carcinogenesis is accelerated in Lynch syndrome, an intensive colonoscopic surveillance program has been recommended si...

journal_title：Gastroenterology

authors： Vasen HF,Abdirahman M,Brohet R,Langers AM,Kleibeuker JH,van Kouwen M,Koornstra JJ,Boot H,Cats A,Dekker E,Sanduleanu S,Poley JW,Hardwick JC,de Vos Tot Nederveen Cappel WH,van der Meulen-de Jong AE,Tan TG,Jacobs MA,Mohame

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND & AIMS:Induction of heat-shock protein 72 is associated with enhanced tolerance to subsequent nonthermal stresses. This study evaluated whether induction of heat-shock protein 72 protects against intestinal ischemia/reperfusion injury. METHODS:Groups of nonheated and heated rats underwent sham operation, 30...

journal_title：Gastroenterology

authors： Stojadinovic A,Kiang J,Smallridge R,Galloway R,Shea-Donohue T

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND & AIMS:Biliary epithelial cells are the target of numerous immune-mediated liver diseases, yet their role in pathogenesis remains unclear because of difficulties in obtaining pure preparations. The aim of this study was to establish pure clones of immortalized murine intrahepatic biliary epithelial cells. M...

journal_title：Gastroenterology

authors： Paradis K,Le ON,Russo P,St-Cyr M,Fournier H,Bu D

更新日期：1995-10-01 00:00:00

abstract：:This document presents the official recommendations of the American Gastroenterological Association (AGA) Institute on "Use of Gastrointestinal Medications in Pregnancy." It was approved by the Clinical Practice and Economics Committee on February 22, 2006, and by the AGA Institute Governing Board on April 20, 2006. ...

journal_title：Gastroenterology

authors： Mahadevan U,Kane S

更新日期：2006-07-01 00:00:00

abstract：:To determine whether pancreatic polypeptide (PP) is a physiologic inhibitor of pancreatic secretion, we have studied the effects of normal rabbit serum and anti-PP serum on pancreatic secretion during infusion of a physiologic dose of PP or intragastric food instillation in dogs. Infusion of 180 pmol/kg X h of PP, pre...

journal_title：Gastroenterology

authors： de Jong AJ,Singer MV,Lamers CB

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND & AIMS:We assessed the risk of ulcers with low-dose aspirin and the interaction of low-dose aspirin with a COX-2 selective inhibitor in a double-blind trial that compared placebo, low-dose aspirin, rofecoxib + low-dose aspirin, and ibuprofen. METHODS:Osteoarthritis patients > or =50 years of age without ulc...

journal_title：Gastroenterology

authors： Laine L,Maller ES,Yu C,Quan H,Simon T

更新日期：2004-08-01 00:00:00

abstract：:The role of cholinergic mechanisms in the control of gallbladder emptying has not been defined. In this report a scintigraphic technique using 2,6-dimethylphenylcarbamoylmethyl iminodiacetic acid labeled with technetium 99m to visualize the gallbladder and its emptying and diethylenetriamine pentaacetic acid labeled w...

journal_title：Gastroenterology

authors： Fisher RS,Rock E,Malmud LS

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND & AIMS:Current stool DNA tests identify about half of individuals with colorectal cancers and miss most individuals with advanced adenomas. We developed a digital melt curve (DMC) assay to quantify low-abundance mutations in stool samples for detection of colorectal neoplasms and compared this test with othe...

journal_title：Gastroenterology

authors： Zou H,Taylor WR,Harrington JJ,Hussain FT,Cao X,Loprinzi CL,Levine TR,Rex DK,Ahnen D,Knigge KL,Lance P,Jiang X,Smith DI,Ahlquist DA

更新日期：2009-02-01 00:00:00

abstract：:Endosonography was performed preoperatively in 33 patients with common bile duct carcinoma and in 43 patients with carcinoma of the common hepatic duct and its bifurcation. The results were correlated with the histology of resected specimens according to the new (1987) TNM (tumor, node, metastasis) classification. End...

journal_title：Gastroenterology

authors： Tio TL,Cheng J,Wijers OB,Sars PR,Tytgat GN

更新日期：1991-05-01 00:00:00

abstract：:Antibodies to a membrane-bound antigen, localized to the canalicular structures of the parietal cell, are found in most sera of patients with chronic atrophic gastritis and pernicious anemia. In the present study immunoglobulins containing parietal cell antibodies were found to inhibit the activity of H+,K+-adenosine ...

journal_title：Gastroenterology

authors： Burman P,Mårdh S,Norberg L,Karlsson FA

更新日期：1989-06-01 00:00:00

abstract：:Fc receptor-mediated clearance of immunoglobulin G-coated autologous erythrocytes was studied in patients with primary biliary cirrhosis (n = 14), alcoholic liver cirrhosis (n = 5) and healthy reference individuals (n = 14). The mean half-life of the sensitized erythrocytes was significantly prolonged in patients with...

journal_title：Gastroenterology

authors： Ekdahl KN,Lööf L,Nyberg A,Nilsson UR,Nilsson B

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND & AIMS:Progressive familial intrahepatic cholestasis can be caused by mutations in ABCB4 or ATP8B1; each encodes a protein that translocates phospholipids, but in opposite directions. ABCB4 flops phosphatidylcholine from the inner to the outer leaflet, where it is extracted by bile salts. ATP8B1, in complex ...

journal_title：Gastroenterology

authors： Groen A,Romero MR,Kunne C,Hoosdally SJ,Dixon PH,Wooding C,Williamson C,Seppen J,Van den Oever K,Mok KS,Paulusma CC,Linton KJ,Oude Elferink RP

更新日期：2011-11-01 00:00:00

abstract：:The aim of this study was to assess the effect of cell culture on the bradykinin receptor of rabbit colon myocytes. In longitudinal muscle strips prepared from distal colon, bradykinin stimulated dose-dependent contraction that was 62% of the maximal response to bethanecol. At 4 degrees C, [3H]bradykinin binding to fr...

journal_title：Gastroenterology

authors： Hyman PE,Diego A,Ridout D,Yuan QX,Ennes H,Cominelli F,Snape WJ Jr,Tomomasa T

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND & AIMS:Barrett's esophagus-associated high-grade dysplasia is commonly treated by endoscopy. However, most guidelines offer no recommendations for endoscopic treatment of mucosal adenocarcinoma of the esophagus (mAC). We investigated the efficacy and safety of endoscopic resection in a large series of patien...

journal_title：Gastroenterology

authors： Pech O,May A,Manner H,Behrens A,Pohl J,Weferling M,Hartmann U,Manner N,Huijsmans J,Gossner L,Rabenstein T,Vieth M,Stolte M,Ell C

更新日期：2014-03-01 00:00:00

abstract：:We report the case of a female patient suffering from Waldenström's macroglobulinemia with three different liver lesions: peliosis hepatis, nodular regenerative hyperplasia, and light-chain deposits within the sinusoidal walls. We hypothesize that both peliosis hepatis and nodular regenerative hyperplasia might be the...

journal_title：Gastroenterology

authors： Voinchet O,Degott C,Scoazec JY,Feldmann G,Benhamou JP

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND & AIMS:We evaluated etanercept, a human soluble tumor necrosis factor receptor: Fc fusion protein, for the treatment of active Crohn's disease. METHODS:Forty-three patients with moderate to severe Crohn's disease were enrolled in an 8-week placebo-controlled trial. Patients were randomized to subcutaneous e...

journal_title：Gastroenterology

authors： Sandborn WJ,Hanauer SB,Katz S,Safdi M,Wolf DG,Baerg RD,Tremaine WJ,Johnson T,Diehl NN,Zinsmeister AR

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND & AIMS:The lipocalin superfamily, including the mouse and human homologues 24p3/lcn2 and neutrophil gelatinase-associated lipocalin, show great functional diversity including roles in olfaction, transportation, and prostaglandin synthesis in mammals. Their potential role in maintaining gastrointestinal mucos...

journal_title：Gastroenterology

authors： Playford RJ,Belo A,Poulsom R,Fitzgerald AJ,Harris K,Pawluczyk I,Ryon J,Darby T,Nilsen-Hamilton M,Ghosh S,Marchbank T

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND & AIMS:Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) are potent antiviral agents that might have additive or synergistic antiviral activity in treatment of patients with chronic hepatitis B (CHB). We compared the efficacy and safety of ETV monotherapy with those of a combination of ETV and TDF. ME...

journal_title：Gastroenterology

authors： Lok AS,Trinh H,Carosi G,Akarca US,Gadano A,Habersetzer F,Sievert W,Wong D,Lovegren M,Cohen D,Llamoso C

更新日期：2012-09-01 00:00:00

abstract：:The diagnosis of inflammatory bowel disease (IBD) with its 2 main subforms, Crohn's disease and ulcerative colitis, is based on clinical, endoscopic, radiologic, and histologic criteria. This paradigm remains unchanged despite the advent of new molecular technologies for the examination of serum proteins and genetic s...

journal_title：Gastroenterology

authors： Nikolaus S,Schreiber S

更新日期：2007-11-01 00:00:00

abstract：:Low residue, chemically defined diets containing all essential nutrients in a readily assimilated form, require minimal digestion and are almost entirely absorbed in the upper gastrointestinal tract. Within the past decade, these diets have been reported to provide nutritional support in a variety of clinical situatio...

journal_title：Gastroenterology

authors： Young EA,Heuler N,Russell P,Weser E

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND & AIMS:The activation of Wnt/beta-catenin signaling causes the development of gastric and colon cancers. Sox17 represses Wnt/beta-catenin signaling and is down-regulated in colon cancer. This study was designed to elucidate the role of Sox17 during the course of gastrointestinal tumorigenesis. METHODS:Sox17...

journal_title：Gastroenterology

authors： Du YC,Oshima H,Oguma K,Kitamura T,Itadani H,Fujimura T,Piao YS,Yoshimoto T,Minamoto T,Kotani H,Taketo MM,Oshima M

更新日期：2009-10-01 00:00:00