Using Teleost Fish to Discern Developmental Signatures of Evolutionary Adaptation From Phenotypic Plasticity in Brain Structure.

abstract：:We evaluated the neuropil distribution of the enzymes NADPH diaphorase (NADPH-d) and cytochrome oxidase (CO) in the spinal cord of the agouti, a medium-sized diurnal rodent, together with the distribution pattern and morphometrical characteristics of NADPH-d reactive neurons across different spinal segments. Neuropil ...

journal_title：Frontiers in neuroanatomy

authors： Freire MA,Tourinho SC,Guimarães JS,Oliveira JL,Picanço-Diniz CW,Gomes-Leal W,Pereira A

更新日期：2008-05-26 00:00:00

abstract：:Over the last 60 years, the spotlight of research has periodically returned to the cerebellum as new techniques and insights have emerged. Because of its simple homogeneous structure, limited diversity of cell types and characteristic behavioral pathologies, the cerebellum is a natural home for studies of cell specifi...

journal_title：Frontiers in neuroanatomy

authors： Basson MA,Wingate RJ

更新日期：2013-09-03 00:00:00

abstract：:Embryonic development in mammals has evolved a platform for genomic conflict between mothers and embryos and, by extension, between maternal and paternal genomes. The evolutionary interests of the mother and embryo may be maximized through the promotion of sex-chromosome genes and imprinted alleles, resulting in the r...

journal_title：Frontiers in neuroanatomy

authors： Lewitus E,Kalinka AT

更新日期：2013-04-09 00:00:00

abstract：:The claustrum is a narrow subcortical brain structure that resides between the striatum and insular cortex. The function of the claustrum is not fully described, and while our previous work supports a role for the claustrum in top-down cognitive control of action, other evidence suggests the claustrum may be involved ...

journal_title：Frontiers in neuroanatomy

authors： Qadir H,Krimmel SR,Mu C,Poulopoulos A,Seminowicz DA,Mathur BN

更新日期：2018-11-26 00:00:00

abstract：:Gaucher's disease (GD) is the most prevalent lysosomal storage disorder. GD is caused by homozygous mutations of the GBA1 gene, which codes for beta-glucocerebrosidase (GCase). Although GD primarily affects peripheral tissues, the presence of neurological symptoms has been reported in several GD subtypes. GBA1 mutatio...

journal_title：Frontiers in neuroanatomy

authors： Franco R,Sánchez-Arias JA,Navarro G,Lanciego JL

更新日期：2018-06-28 00:00:00

abstract：:Although the olfactory sense has always been considered with less interest than the visual, auditive or somatic senses, it does plays a major role in our ordinary life, with important implication in dangerous situations or in social and emotional behaviors. Traditional Diffusion Tensor signal model and related tractog...

journal_title：Frontiers in neuroanatomy

authors： Milardi D,Cacciola A,Calamuneri A,Ghilardi MF,Caminiti F,Cascio F,Andronaco V,Anastasi G,Mormina E,Arrigo A,Bruschetta D,Quartarone A

更新日期：2017-04-10 00:00:00

abstract：:Human inducible pluripotent stem cells (hiPSCs) hold a large potential for disease modeling. hiPSC-derived human astrocyte and neuronal cultures permit investigations of neural signaling pathways with subcellular resolution. Combinatorial cultures, and three-dimensional (3-D) embryonic bodies (EBs) enlarge the scope o...

journal_title：Frontiers in neuroanatomy

authors： Rakotoson I,Delhomme B,Djian P,Deeg A,Brunstein M,Seebacher C,Uhl R,Ricard C,Oheim M

更新日期：2019-08-20 00:00:00

abstract：:Despite many structural and functional aspects of the brain organization have been extensively studied in neuroscience, we are still far from a clear understanding of the intricate structure-function interactions occurring in the multi-layered brain architecture, where billions of different neurons are involved. Altho...

journal_title：Frontiers in neuroanatomy

authors： Ullo S,Nieus TR,Sona D,Maccione A,Berdondini L,Murino V

更新日期：2014-11-20 00:00:00

abstract：:Hippocampal sclerosis is the most frequent pathology encountered in resected mesial temporal structures from patients with intractable temporal lobe epilepsy (TLE). Here, we have used stereological methods to compare the overall density of synapses and neurons between non-sclerotic and sclerotic hippocampal tissue obt...

journal_title：Frontiers in neuroanatomy

authors： Alonso-Nanclares L,Kastanauskaite A,Rodriguez JR,Gonzalez-Soriano J,Defelipe J

更新日期：2011-02-24 00:00:00

abstract：:This study presents a tool, Neuronize, for building realistic three-dimensional models of neuronal cells from the morphological information extracted through computer-aided tracing applications. Neuronize consists of a set of methods designed to build 3D neural meshes that approximate the cell membrane at different re...

journal_title：Frontiers in neuroanatomy

authors： Brito JP,Mata S,Bayona S,Pastor L,Defelipe J,Benavides-Piccione R

更新日期：2013-06-03 00:00:00

abstract：:Calcium stores in neurons are heterogeneous in compartmentalization and molecular composition. Danio rerio (zebrafish) is an animal model with a simply folded cerebellum similar in cellular organization to that of mammals. The aim of the study was to identify new endoplasmic reticulum (ER) calcium store markers in zeb...

journal_title：Frontiers in neuroanatomy

authors： Furlan S,Campione M,Murgia M,Mosole S,Argenton F,Volpe P,Nori A

更新日期：2020-04-21 00:00:00

abstract：:Immunohistochemistry (IHC) is a valuable method for identifying discrete neurochemical molecules by the interaction of target antigens with validated antibodies tagged with a visible label (e.g., peroxidase). We have developed an immunostaining method that is highly sensitive in detection of neurochemical antigens. Ou...

journal_title：Frontiers in neuroanatomy

authors： Goto S,Morigaki R,Okita S,Nagahiro S,Kaji R

更新日期：2015-03-03 00:00:00

abstract：:Dopamine (DA) modulates the effects of amino acid neurotransmitters (AANs), including GABA and glutamate, in motor, visual, olfactory, and reward systems (Hnasko et al., 2010; Stuber et al., 2010; Hnasko and Edwards, 2012). The results suggest that DA may play a similar modulatory role in the auditory pathways. Previo...

journal_title：Frontiers in neuroanatomy

authors： Fyk-Kolodziej BE,Shimano T,Gafoor D,Mirza N,Griffith RD,Gong TW,Holt AG

更新日期：2015-07-22 00:00:00

abstract：:Brain tissue contains autofluorescing elements that potentially impede accurate identification of neurons when visualized with fluorescent microscopy. Age-related accumulation of molecules with autofluorescent properties, such as lipofuscin, can possess spectral profiles that invade the typical emission range of fluor...

journal_title：Frontiers in neuroanatomy

authors： Pyon WS,Gray DT,Barnes CA

更新日期：2019-07-18 00:00:00

abstract：:A subset of monoamine neurons releases glutamate as a cotransmitter due to presence of the vesicular glutamate transporters VGLUT2 or VGLUT3. In addition to mediating vesicular loading of glutamate, it has been proposed that VGLUT3 enhances serotonin (5-HT) vesicular loading by the vesicular monoamine transporter (VMA...

journal_title：Frontiers in neuroanatomy

authors： Voisin AN,Mnie-Filali O,Giguère N,Fortin GM,Vigneault E,El Mestikawy S,Descarries L,Trudeau LÉ

更新日期：2016-04-12 00:00:00

abstract：:Dual transneuronal tracing is a novel viral tracing methodology which employs two recombinant viruses, each expressing a different reporter protein. Peripheral injection of recombinant pseudorabies viruses has been used as a powerful method to define neurons that coordinate outputs to various peripheral targets of mot...

journal_title：Frontiers in neuroanatomy

authors： Ohara S,Inoue K,Yamada M,Yamawaki T,Koganezawa N,Tsutsui K,Witter MP,Iijima T

更新日期：2009-01-19 00:00:00

abstract：:Until recently it was widely believed that the ability of female mammals (with the likely exception of women) to identify and seek out a male breeding partner relied on the detection of non-volatile male pheromones by the female's vomeronasal organ (VNO) and their subsequent processing by a neural circuit that include...

journal_title：Frontiers in neuroanatomy

authors： Baum MJ

更新日期：2012-06-05 00:00:00

abstract：:The reeler mouse has been widely used to study various aspects of cortico- and synaptogenesis, but also as a model for several neurological and neurodegenerative disorders. In contrast to development, comparably little is known about the neuronal composition and synaptic organization of the adult reeler mouse neocorte...

journal_title：Frontiers in neuroanatomy

authors： Prume M,Rollenhagen A,Lübke JHR

更新日期：2018-10-05 00:00:00

abstract：:The neural circuits involved in mediating complex behaviors are being rapidly elucidated using various newly developed and powerful anatomical and molecular techniques, providing insights into the neural basis for anxiety disorders, depression, addiction, and dysfunctional social behaviors. Many of these behaviors and...

journal_title：Frontiers in neuroanatomy

authors： Santos FN,Pereira CW,Sánchez-Pérez AM,Otero-García M,Ma S,Gundlach AL,Olucha-Bordonau FE

更新日期：2016-04-07 00:00:00

abstract：:The caudal region of the rodent striatum, called the tail of the striatum (TS), is a relatively small area but might have a distinct function from other striatal subregions. Recent primate studies showed that this part of the striatum has a unique function in encoding long-term value memory of visual objects for habit...

journal_title：Frontiers in neuroanatomy

authors： Jiang H,Kim HF

更新日期：2018-05-03 00:00:00

abstract：:Dendrite and dendritic spine formation are crucial for proper brain function. DISC1-binding zinc finger protein (DBZ) was first identified as a Disrupted-In-Schizophrenia1 (DISC1) binding partner. DBZ is highly expressed in the cerebral cortex of developing and adult rodents and is involved in neurite formation, cell ...

journal_title：Frontiers in neuroanatomy

authors： Koyama Y,Hattori T,Nishida T,Hori O,Tohyama M

更新日期：2015-04-30 00:00:00

abstract：:The thalamocingulate tract is a key component of the Papez circuit that connects the anterior thalamic nucleus (ATN) to the cingulum bundle. While the other white matter connections, consisting of the fornix, cingulum bundle and mammillothalamic tract, were well defined in Papez's original 1937 paper, the anatomy of t...

journal_title：Frontiers in neuroanatomy

authors： Weininger J,Roman E,Tierney P,Barry D,Gallagher H,Murphy P,Levins KJ,O'Keane V,O'Hanlon E,Roddy DW

更新日期：2019-02-18 00:00:00

abstract：:Biological impacts of light beyond vision, i.e., non-visual functions of light, signify the need to better understand light detection (or photoreception) systems in vertebrates. Photopigments, which comprise light-absorbing chromophores bound to a variety of G-protein coupled receptor opsins, are responsible for visua...

journal_title：Frontiers in neuroanatomy

authors： Hang CY,Kitahashi T,Parhar IS

更新日期：2016-04-27 00:00:00

abstract：:Emotions depend upon the integrated activity of neural networks that modulate arousal, autonomic function, motor control, and somatosensation. Brainstem nodes play critical roles in each of these networks, but prior studies of the neuroanatomic basis of emotion, particularly in the human neuropsychological literature,...

journal_title：Frontiers in neuroanatomy

authors： Venkatraman A,Edlow BL,Immordino-Yang MH

更新日期：2017-03-09 00:00:00

abstract：:Dendritic spines are key components of a variety of microcircuits and they represent the majority of postsynaptic targets of glutamatergic axon terminals in the brain. The present article will focus on the discovery of dendritic spines, which was possible thanks to the application of the Golgi technique to the study o...

journal_title：Frontiers in neuroanatomy

authors： DeFelipe J

更新日期：2015-03-05 00:00:00

abstract：:How does the size of the glial and neuronal cells that compose brain tissue vary across brain structures and species? Our previous studies indicate that average neuronal size is highly variable, while average glial cell size is more constant. Measuring whole cell sizes in vivo, however, is a daunting task. Here we use...

journal_title：Frontiers in neuroanatomy

authors： Mota B,Herculano-Houzel S

更新日期：2014-11-12 00:00:00

abstract：:Enough species have now been subject to systematic quantitative analysis of the relationship between the morphology and cellular composition of their brain that patterns begin to emerge and shed light on the evolutionary path that led to mammalian brain diversity. Based on an analysis of the shared and clade-specific ...

journal_title：Frontiers in neuroanatomy

authors： Herculano-Houzel S,Manger PR,Kaas JH

更新日期：2014-08-11 00:00:00

abstract：:Experimentalallergic encephalomyelitis (EAE) is an animal model for inflammatory demyelinating autoimmune disease, i.e., multiple sclerosis (MS). In the present study, we investigated the antineuroinflammatory/neuroprotective effects of C16, an ανβ3 integrin-binding peptide, and recombinant rat ciliary neurotrophic fa...

journal_title：Frontiers in neuroanatomy

authors： Fang M,He D,Zhang F,Hu Z,Yang J,Jiang H,Han S

更新日期：2013-12-30 00:00:00

abstract：:Experiments in several species have identified direct projections to the medial geniculate nucleus (MG) from cells in subcollicular auditory nuclei. Moreover, many cochlear nucleus cells that project to the MG send collateral projections to the inferior colliculus (IC) (Schofield et al., 2014). We conducted three expe...

journal_title：Frontiers in neuroanatomy

authors： Schofield BR,Mellott JG,Motts SD

更新日期：2014-07-18 00:00:00

abstract：:Anatomically distinct areas within the basal ganglia encode flexible- and stable-value memories for visual objects (Hikosaka et al., 2014), but an important question remains: do they receive inputs from the same or different brain areas or neurons? To answer this question, we first located flexible and stable value-co...

journal_title：Frontiers in neuroanatomy

authors： Griggs WS,Kim HF,Ghazizadeh A,Costello MG,Wall KM,Hikosaka O

更新日期：2017-11-24 00:00:00