Errors in Diagnostic Test Use and Interpretation Contribute to the High Number of Lyme Disease Referrals in a Low-Incidence State.

abstract：:Background.  Advanced fibrosis occurs more commonly in human immunodeficiency virus (HIV)-hepatitis B virus (HBV) coinfected individuals; therefore, fibrosis monitoring is important in this population. However, transient elastography (TE) data in HIV-HBV coinfection are lacking. We aimed to assess liver fibrosis using...

journal_title：Open forum infectious diseases

authors： Audsley J,Robson C,Aitchison S,Matthews GV,Iser D,Sasadeusz J,Lewin SR

更新日期：2016-02-12 00:00:00

abstract：:Cryptococcus gattii represents an emerging fungal pathogen of immunocompromised and immunocompetent hosts in the United States. To our knowledge, this is the first case of posttransplant immune reconstitution syndrome due to C. gattii meningoencephalitis successfully treated with corticosteroids. We also report succes...

journal_title：Open forum infectious diseases

authors： Canfield GS,Henao-Martínez AF,Franco-Paredes C,Zhelnin K,Wilson ML,Shihadeh KC,Wyles D,Gardner EM

更新日期：2019-10-23 00:00:00

abstract：:During 12 recent months of periodic influenza virus surveillance at 9 live poultry markets in Wuxi City China, we identified multiple highly pathogenic H5N6, H5N8, H5N2, and H5N1 avian influenza viruses. The variety of potentially pandemic viruses in this low-risk area is disconcerting and portends an increased pandem...

journal_title：Open forum infectious diseases

authors： Ma MJ,Chen SH,Wang GL,Zhao T,Qian YH,Wu MN,Liu Y,Gray GC,Lu B,Cao WC

更新日期：2016-03-09 00:00:00

abstract：:Because of concerns about possible emergence of artemisinin resistance strains of Plasmodium falciparum in mining areas of the interior of Guyana, a 7-day artesunate trial was conducted from March to December 2014. The day-3 parasite clearance rate, the efficacy of artesunate at day 28, and polymorphism of Kelch 13 (P...

journal_title：Open forum infectious diseases

authors： Rahman R,Martin MJ,Persaud S,Ceron N,Kellman D,Musset L,Carter KH,Ringwald P

更新日期：2016-08-30 00:00:00

abstract：:We report a rare case of acute human immunodeficiency virus (HIV) syndrome in a patient with chronic HIV infection with acute illness indistinguishable from acute retroviral syndrome. The patient presented with an acute febrile mononucleosis-like illness after increasing nonadherence to antiretroviral therapy. A marke...

journal_title：Open forum infectious diseases

authors： Choi SK,Graber CJ

更新日期：2014-12-23 00:00:00

abstract：:Far East scarlet-like fever (FESLF) is a severe inflammatory disease that occurs sporadically and in outbreaks in Russia and Japan. Far East scarlet-like fever is caused by Yersinia pseudotubuclosis infection, an organism that typically causes self-limiting gastroenteritis in Europe. Studies suggest the ability of Far...

journal_title：Open forum infectious diseases

authors： Amphlett A

更新日期：2015-12-17 00:00:00

abstract：:The spectrum of West Nile virus (WNV) infection continues to be elucidated. Many cases of WNV are asymptomatic; however, in immunocompromised patients, symptoms are more likely to be severe. We describe fatal WNV central nervous system disease in lymphoma patients who received rituximab, blunting the inflammatory resp...

journal_title：Open forum infectious diseases

authors： Morjaria S,Arguello E,Taur Y,Sepkowitz K,Hatzoglou V,Nemade A,Rosenblum M,Cavalcanti MS,Palomba ML,Kaltsas A

更新日期：2015-09-19 00:00:00

abstract：:The role of empirical and even directed antimicrobial management of patients hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is problematic; antibiotics are used frequently among these patients to treat confirmed or suspected coinfection or just the symptoms. In the rapidly cha...

journal_title：Open forum infectious diseases

authors： Goldstein EJC,Tillotson G,Redell M

更新日期：2020-10-26 00:00:00

abstract：Background:From an isolated epidemic, coronavirus disease 2019 has now emerged as a global pandemic. The availability of genomes in the public domain after the epidemic provides a unique opportunity to understand the evolution and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus across the g...

journal_title：Open forum infectious diseases

authors： Banu S,Jolly B,Mukherjee P,Singh P,Khan S,Zaveri L,Shambhavi S,Gaur N,Reddy S,Kaveri K,Srinivasan S,Gopal DR,Siva AB,Thangaraj K,Tallapaka KB,Mishra RK,Scaria V,Sowpati DT

更新日期：2020-09-18 00:00:00

abstract：Background:Hematogenous dissemination of Talaromyces marneffei can result in multiorgan involvement (skin, lung, and reticuloendothelial system involvement); however, few studies have reported intestinal T marneffei infections. We investigated clinical features, management, and patient outcomes concerning Talaromyces-r...

journal_title：Open forum infectious diseases

authors： Pan M,Huang J,Qiu Y,Zeng W,Li Z,Tang S,Wei X,Zhang J

更新日期：2020-04-27 00:00:00

abstract：BACKGROUND:Clostridium difficile infection (CDI) is no longer restricted to hospital settings, and population-based incidence measures are needed. Understanding the determinants of CDI incidence will allow for more meaningful comparisons of rates and accurate national estimates. METHODS:Data from active population- an...

journal_title：Open forum infectious diseases

authors： Lessa FC,Mu Y,Winston LG,Dumyati GK,Farley MM,Beldavs ZG,Kast K,Holzbauer SM,Meek JI,Cohen J,McDonald LC,Fridkin SK

更新日期：2014-07-28 00:00:00

abstract：Background:Cavitary lesions (CLs) primarily identified by chest x-ray (CXR) have been associated with worse clinical outcomes among patients with pulmonary tuberculosis (PTB). Chest computed tomography (CT), which has better resolution and increased sensitivity to detect lung abnormalities, has been understudied in PTB...

journal_title：Open forum infectious diseases

authors： Hernandez-Romieu AC,Little BP,Bernheim A,Schechter MC,Ray SM,Bizune D,Kempker R

更新日期：2019-06-24 00:00:00

abstract：Background:Patients heterozygous for mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene may be more susceptible to respiratory infections than the general population. Methods :We conducted a retrospective case-control study using health insurance claims. We identified patients as either h...

journal_title：Open forum infectious diseases

authors： Polgreen PM,Brown GD,Hornick DB,Ahmad F,London B,Stoltz DA,Comellas AP

更新日期：2018-11-01 00:00:00

abstract：:Background.  Hepatitis C virus (HCV) treatment access among human immunodeficiency virus (HIV)/HCV-coinfected people who inject drugs is poor, despite a high burden of disease in this population. Understanding barriers and facilitators to HCV treatment uptake is critical to the implementation of new direct-acting anti...

journal_title：Open forum infectious diseases

authors： Chu CE,Wu F,He X,Zhou K,Cheng Y,Cai W,Geng E,Volberding P,Tucker JD

更新日期：2016-06-24 00:00:00

abstract：BACKGROUND:Avian influenza A/H5N1 has threatened human health for nearly 2 decades. Avian influenza A vaccine without adjuvant is poorly immunogenic. A flexible rapid tactic for mass vaccination will be needed if a pandemic occurs. METHODS:A multicenter, randomized, blinded phase 1 clinical trial evaluated safety and ...

journal_title：Open forum infectious diseases

authors： Mulligan MJ,Bernstein DI,Frey S,Winokur P,Rouphael N,Dickey M,Edupuganti S,Spearman P,Anderson E,Graham I,Noah DL,Mangal B,Kim S,Hill H,Whitaker J,Emery W,Beck A,Stephens K,Hartwell B,Ogilvie M,Rimann N,Osinski

更新日期：2014-11-18 00:00:00

abstract：:Naegleria fowleri is a thermophilic free-living amoeba that is found in warm, fresh water and causes primary amebic meningoencephalitis (PAM). The following report demonstrates the rapid and destructive clinical features of PAM in an 8-year-old male who presented with severe headaches approximately 12 days after swimm...

journal_title：Open forum infectious diseases

authors： Vareechon C,Tarro T,Polanco C,Anand V,Pannaraj PS,Dien Bard J

更新日期：2019-07-29 00:00:00

abstract：:Skin and soft tissue infections (SSTI) affect millions of people globally, which represents a significant burden on ambulatory care and hospital settings. The role of sulfamethoxazole-trimethoprim (SXT) in SSTI treatment, particularly when group A Streptococcus (GAS) is involved, is controversial. We conducted a syste...

journal_title：Open forum infectious diseases

authors： Bowen AC,Carapetis JR,Currie BJ,Fowler V Jr,Chambers HF,Tong SYC

更新日期：2017-11-02 00:00:00

abstract：:The FilmArray meningitis/encephalitis (ME) panel is a novel syndromic, nucleic acid amplification test for diagnosis of acute meningitis and encephalitis. Emerging data on its performance are concerning for false-positive results. We present a case of tuberculous meningitis misdiagnosed as herpes simplex virus-1 encep...

journal_title：Open forum infectious diseases

authors： Gomez CA,Pinsky BA,Liu A,Banaei N

更新日期：2016-12-07 00:00:00

abstract：Background:In the outpatient setting, the majority of antibiotic prescriptions are for acute respiratory infections (ARIs), but most of these infections are viral and antibiotics are unnecessary. We analyzed provider-specific antibiotic prescribing in a group of outpatient clinics affiliated with an academic medical ce...

journal_title：Open forum infectious diseases

authors： Jung S,Sexton ME,Owens S,Spell N,Fridkin S

更新日期：2019-01-18 00:00:00

abstract：:Background.  First- and second-generation smallpox vaccines are contraindicated in individuals infected with human immunodeficiency virus (HIV). A new smallpox vaccine is needed to protect this population in the context of biodefense preparedness. The focus of this study was to compare the safety and immunogenicity of...

journal_title：Open forum infectious diseases

authors： Overton ET,Stapleton J,Frank I,Hassler S,Goepfert PA,Barker D,Wagner E,von Krempelhuber A,Virgin G,Meyer TP,Müller J,Bädeker N,Grünert R,Young P,Rösch S,Maclennan J,Arndtz-Wiedemann N,Chaplin P

更新日期：2015-05-05 00:00:00

abstract：Background:Although existing literature supports durations of 5-7 days for skin and soft tissue infections (SSTIs), longer durations are commonly used. Obesity and heart failure (HF) have been associated with increased risk for treatment failure of SSTIs; however, whether prolonged antibiotic durations reduce the risk ...

journal_title：Open forum infectious diseases

authors： Ihm C,Sutton JD,Timbrook TT,Spivak ES

更新日期：2019-05-07 00:00:00

abstract：:We present a case of a 20-year-old male who had ambiguous HIV test results after entering new provider care and whose status was later complicated by undetectable viral RNA off antiretroviral therapy (ART). Verifying HIV infection status may occasionally require sensitive DNA testing that might need to be considered i...

journal_title：Open forum infectious diseases

authors： Springer SA,Masciotra S,Johnson JA,Campbell S

更新日期：2020-10-10 00:00:00

abstract：:Background.  During pregnancy, the placenta is inaccessible for diagnosis of placental malaria (PM), but soluble tumor necrosis factor-α receptors (sTNFR) are elevated in the plasma of women with PM. Methods.  In this study, sTNFR-1 and sTNFR-2 were quantified in urine of pregnant and nonpregnant Cameroonian women who...

journal_title：Open forum infectious diseases

authors： Tassi Yunga S,Thévenon AD,Leke RG,Taylor DW

更新日期：2016-04-26 00:00:00

abstract：:In this study, we report a complete (clinical, radiological, and virological) sustained (1 year) response after nivolumab salvage therapy in a progressive multifocal leukoencephalopathy patient. Analyses of the cells infiltrate in a pretreatment brain biopsy suggest that parenchymal programmed cell death-L1+ macrophag...

journal_title：Open forum infectious diseases

authors： Audemard-Verger A,Gasnault J,Faisant M,Besse MC,Martin-Silva N,Berra M,Fournier L,Boutemy J,Maigne G,De Boysson H,Ruet A,Vabret A,Chapon F,Martin-Blondel G,Aouba A

更新日期：2019-09-30 00:00:00

abstract：Background:The use of a "trial of antibiotics" as empiric therapy for bacterial pneumonia as a diagnostic tool for tuberculosis in people with HIV (PWH) was removed from World Health Organization (WHO) recommendations in 2007, based on expert opinion. Current guidelines recommend antibiotics only after 2 Xpert MTB/RIF ...

journal_title：Open forum infectious diseases

authors： Boyles TH,Nduna M,Pitsi T,Scott L,Fox MP,Maartens G

更新日期：2020-01-06 00:00:00

abstract：Background:Clinical features of Lyme disease (LD) range from localized skin lesions to serious disseminated disease. Information on risk factors for Lyme arthritis, facial palsy, carditis, and meningitis is limited but could facilitate disease recognition and elucidate pathophysiology. Methods:Patients from high-incid...

journal_title：Open forum infectious diseases

authors： Kwit NA,Nelson CA,Max R,Mead PS

更新日期：2017-11-18 00:00:00

abstract：Background:We characterized the extent of antiretroviral therapy (ART) experience and postdischarge mortality among hospitalized HIV-infected adults in Zambia. Methods:At a central hospital with an opt-out HIV testing program, we enrolled HIV-infected adults (18+ years) admitted to internal medicine using a population...

journal_title：Open forum infectious diseases

authors： Haachambwa L,Kandiwo N,Zulu PM,Rutagwera D,Geng E,Holmes CB,Sinkala E,Claassen CW,Mugavero MJ,Wa Mwanza M,Turan JM,Vinikoor MJ

更新日期：2019-07-16 00:00:00

abstract：BACKGROUND:Lack of human immunodeficiency virus (HIV) infection awareness may be a driver of racial disparities in HIV infection among men who have sex with men (MSM). Lack of awareness is typically measured by comparing HIV test result to self-reported HIV status. This measure may be subject to reporting bias and alte...

journal_title：Open forum infectious diseases

authors： Sanchez TH,Kelley CF,Rosenberg E,Luisi N,O'Hara B,Lambert R,Coleman R,Frew P,Salazar LF,Tao S,Clarke W,Del Rio C,Sullivan PS

更新日期：2014-09-13 00:00:00

abstract：:Background.  The efficacy of live, attenuated live attenuated influenza vaccine(LAIV) and inactivated influenza vaccine(IIV) is poorly explained by either single or composite immune responses to vaccination. Protective biomarkers were therefore studied in response to LAIV or IIV followed by LAIV challenge in children....

journal_title：Open forum infectious diseases

authors： Wright PF,Hoen AG,Ilyushina NA,Brown EP,Ackerman ME,Wieland-Alter W,Connor RI,Jegaskanda S,Rosenberg-Hasson Y,Haynes BC,Luke CJ,Subbarao K,Treanor JJ

更新日期：2016-05-23 00:00:00

abstract：:Immune suppression is a recognized risk factor for necrotizing fasciitis. In patients with hematological malignancies, a profoundly immunocompromised group, the predominant causative organisms are Gram negative. Clinical presentation and outcomes in these patients are similar to the immunocompetent. The Laboratory Ris...

journal_title：Open forum infectious diseases

authors： Foo RM,Tung ML,Poon LM,Chan D,Smitasin N,Koh LP,Chng WJ,Chai LY

更新日期：2015-06-12 00:00:00