Immune Defenses of a Beneficial Pest: The Mealworm Beetle, Tenebrio molitor.

abstract：:Heat shock proteins are molecular chaperones that are involved in numerous normal cellular processes and stress responses, and heat shock factors are transcriptional activators of heat shock proteins. Heat shock factors and heat shock proteins are coordinated in various biological processes. The regulatory function of...

journal_title：Frontiers in physiology

authors： Jin J,Li Y,Zhou Z,Zhang H,Guo J,Wan F

更新日期：2020-09-15 00:00:00

abstract：:The paired cranial sensory organs and peripheral nervous system of vertebrates arise from a thin strip of cells immediately adjacent to the developing neural plate. The neural plate border region comprises progenitors for four key populations of cells: neural plate cells, neural crest cells, the cranial placodes, and ...

journal_title：Frontiers in physiology

authors： Thawani A,Groves AK

更新日期：2020-12-07 00:00:00

abstract：:Apolipophorin III (ApoLp-III) is a well-known hemolymph protein having a functional role in lipid transport and immune responses of insects. Here we report the molecular and functional characterization of Anopheles stephensi Apolipophorin-III (AsApoLp-III) gene. This gene consists of 679 nucleotides arranged into two ...

journal_title：Frontiers in physiology

authors： Dhawan R,Gupta K,Kajla M,Kakani P,Choudhury TP,Kumar S,Kumar V,Gupta L

更新日期：2017-04-07 00:00:00

abstract：:Background: RNase A (the bovine equivalent to human RNase 1) and RNase 5 (angiogenin) are two closely related ribonucleases. RNase 5 is described as a powerful angiogenic factor. Whether RNase A shares the same angiogenic characteristic, or interferes with vessel growth as demonstrated for arteriogenesis, has never be...

journal_title：Frontiers in physiology

authors： Lasch M,Kumaraswami K,Nasiscionyte S,Kircher S,van den Heuvel D,Meister S,Ishikawa-Ankerhold H,Deindl E

更新日期：2020-11-06 00:00:00

abstract：:Aging is a one-way process associated with profound structural and functional changes in the organism. Indeed, the neuromuscular system undergoes a wide remodeling, which involves muscles, fascia, and the central and peripheral nervous systems. As a result, intrinsic features of tissues, as well as their functional an...

journal_title：Frontiers in physiology

authors： Zullo A,Fleckenstein J,Schleip R,Hoppe K,Wearing S,Klingler W

更新日期：2020-06-24 00:00:00

abstract：:Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, play an important role in cellular communication during skeletal growth and homeostasis. Bioactive molecules carried by EVs are transported to neighboring and distant cells to trigger a series of signaling cascades influencing bone ...

journal_title：Frontiers in physiology

authors： Yuan FL,Wu QY,Miao ZN,Xu MH,Xu RS,Jiang DL,Ye JX,Chen FH,Zhao MD,Wang HJ,Li X

更新日期：2018-05-30 00:00:00

abstract：:Although insulin resistance (IR) is a key pathophysiologic condition underlying various metabolic disorders, impaired cellular glucose uptake is one of many manifestations of metabolic derangements in the human body. To study the systems-wide molecular changes associated with obesity-dependent IR, we integrated inform...

journal_title：Frontiers in physiology

authors： Choi H,Koh HWL,Zhou L,Cheng H,Loh TP,Parvaresh Rizi E,Toh SA,Ronnett GV,Huang BE,Khoo CM

更新日期：2019-04-05 00:00:00

abstract：:Treatment with ionizing radiation (IR) remains the cornerstone of therapy for multiple cancer types, including disseminated and aggressive diseases in the palliative setting. Radiotherapy efficacy could be improved in combination with drugs that regulate the ubiquitin-proteasome system (UPS), many of which are current...

journal_title：Frontiers in physiology

authors： Fouad S,Wells OS,Hill MA,D'Angiolella V

更新日期：2019-10-01 00:00:00

abstract：:Muscle fatigue is a serious problem in patients with motor neuron diseases (MNDs). It commonly disturbs both daily life activity and rehabilitation tolerance. A particular concern should be taken when MNDs occur in older ages. Older patients with MNDs usually have a worse clinical presentation and a lower survival rat...

journal_title：Frontiers in physiology

authors： Mohamed AA

更新日期：2019-10-01 00:00:00

abstract：:The gut microbiome is extremely important for maintaining homeostasis with host intestinal epithelial, neuronal, and immune cells and this host-microbe interaction is critical during times of stress or disease. Environmental, nutritional, and cognitive stress are just a few factors known to influence the gut microbiot...

journal_title：Frontiers in physiology

authors： Pearce SC,Coia HG,Karl JP,Pantoja-Feliciano IG,Zachos NC,Racicot K

更新日期：2018-11-12 00:00:00

abstract：:Acute kidney injury (AKI), which involves the loss of kidney function caused by damage to renal tubular cells, is an important public health concern. We previously showed that sirtuin (SIRT)3 protects the kidneys against mitochondrial damage by inhibiting the nucleotide-binding domain (NOD)-like receptor protein 3 (NL...

journal_title：Frontiers in physiology

authors： Zhao W,Zhang L,Chen R,Lu H,Sui M,Zhu Y,Zeng L

更新日期：2018-11-14 00:00:00

abstract：:Characterization of flow properties in cerebral arteries with 1.5 and 3 Tesla MRI is usually limited to large cerebral arteries and difficult to evaluate in the small perforating arteries due to insufficient spatial resolution. In this study, we assessed the feasibility to measure blood flow waveforms in the small len...

journal_title：Frontiers in physiology

authors： Schnerr RS,Jansen JFA,Uludag K,Hofman PAM,Wildberger JE,van Oostenbrugge RJ,Backes WH

更新日期：2017-11-24 00:00:00

abstract：:Background: Recent studies have shown that blood-based miRNAs are dysregulated in patients with acute myocardial infarction (AMI) and are therefore a potential tool for the diagnosis of AMI. Therefore, this study summarized and evaluated studies focused on microRNAs as novel biomarkers for the diagnosis of AMI from th...

journal_title：Frontiers in physiology

authors： Zhai C,Li R,Hou K,Chen J,Alzogool M,Hu Y,Zhang J,Zhang Y,Wang L,Zhang R,Cong H

更新日期：2020-08-14 00:00:00

abstract：:Airway hyperresponsiveness (AHR), a characteristic of asthma that involves an excessive reduction in airway caliber, is a complex mechanism reflecting multiple processes that manifest over a large range of length and time scales. At one extreme, molecular interactions determine the force generated by airway smooth mus...

journal_title：Frontiers in physiology

authors： Lauzon AM,Bates JH,Donovan G,Tawhai M,Sneyd J,Sanderson MJ

更新日期：2012-06-11 00:00:00

abstract：:Untreated chronic hypertension causes left ventricular hypertrophy, which is related to the occurrence of atrial fibrillation. Dronedarone is an antiarrhythmic agent recently approved for atrial fibrillation. Our group previously demonstrated that dronedarone produced an early regression of left ventricular hypertroph...

journal_title：Frontiers in physiology

authors： Pazó-Sayós L,González MC,Quintana-Villamandos B

更新日期：2020-08-26 00:00:00

abstract：:Regular exercise prevents lipid abnormalities and conditions such as diabetes mellitus, hypertension, and obesity; it considerably benefits sedentary individuals. However, individuals exhibit highly variable responses to exercise, probably due to genetic variations. Animal models are typically used to investigate the ...

journal_title：Frontiers in physiology

authors： Tung YT,Hsu YJ,Liao CC,Ho ST,Huang CC,Huang WC

更新日期：2019-09-18 00:00:00

abstract：:The importance of electrolyte concentrations for cardiac function is well established. Electrolyte variations can lead to arrhythmias onset, due to their important role in the action potential (AP) genesis and in maintaining cell homeostasis. However, most of the human AP computer models available in literature were d...

journal_title：Frontiers in physiology

authors： Bartolucci C,Passini E,Hyttinen J,Paci M,Severi S

更新日期：2020-04-15 00:00:00

abstract：:Left ventricular hypertrophy (LVH) is a major contributor to the development of heart failure (HF). Alterations in cyclic adenosine monophosphate (cAMP)-dependent signaling pathways participate in cardiomyocyte hypertrophy and mitochondrial dysfunction occurring in LVH and HF. cAMP signals are received and integrated ...

journal_title：Frontiers in physiology

authors： Schiattarella GG,Boccella N,Paolillo R,Cattaneo F,Trimarco V,Franzone A,D'Apice S,Giugliano G,Rinaldi L,Borzacchiello D,Gentile A,Lombardi A,Feliciello A,Esposito G,Perrino C

更新日期：2018-05-28 00:00:00

abstract：:Objective: Despite the improvement in ventricular assist device (VAD) therapy in adults and in adolescents, in infant population only Berlin Heart EXCOR (BHE) is licensed as long term VAD to bridge children to Heart Transplantation (HTx). Particularly demanding in terms of morbidity and mortality are smallest patients...

journal_title：Frontiers in physiology

authors： Di Molfetta A,Gandolfo F,Filippelli S,Perri G,Di Chiara L,Iacobelli R,Adorisio R,Favia I,Rizza A,Testa G,Di Nardo M,Amodeo A

更新日期：2016-12-06 00:00:00

abstract：:Determining individual health status is of great importance for a better understanding of life history trade-offs between growth, reproduction, and maintenance. However, existing immunological methods are invasive and therefore not suitable for investigating health status in wild populations. Thus, there is an urgent ...

journal_title：Frontiers in physiology

authors： Behringer V,Stevens JM,Leendertz FH,Hohmann G,Deschner T

更新日期：2017-02-06 00:00:00

abstract：:Temporal computations are important in the acoustic communication of anurans. In many cases, calls between closely related species are nearly identical spectrally but differ markedly in temporal structure. Depending on the species, calls can differ in pulse duration, shape and/or rate (i.e., amplitude modulation), dir...

journal_title：Frontiers in physiology

authors： Rose GJ

更新日期：2014-05-30 00:00:00

abstract：:Background:Plutella xylostella has become a notorious pest of cruciferous crops all over the world. Delta-endotoxins of Bacillus thuringiensis are widely used insecticidal proteins for controlling P. xylostella. However, the interaction mechanism of B. thuringiensis with the immune system of P. xylostella, at the geno...

journal_title：Frontiers in physiology

authors： Li S,Xu X,Shakeel M,Xu J,Zheng Z,Zheng J,Yu X,Zhao Q,Jin F

更新日期：2018-11-15 00:00:00

abstract：Background:The development of childhood motor competence demonstrates a high degree of inter-individual variation. Some children's competence levels increase whilst others' competence levels remain unchanged or even decrease over time. However, few studies have examined this developmental change in motor competence acr...

journal_title：Frontiers in physiology

authors： Coppens E,Bardid F,Deconinck FJA,Haerens L,Stodden D,D'Hondt E,Lenoir M

更新日期：2019-10-02 00:00:00

abstract：:The hypothesis of the present study is that apoptosis through an intrinsic mitochondrial pathway may mediate high fat diet (HFD)-induced changes in the metabolism of Pelteobagrus fulvidraco. To this end, we cloned the full-length cDNA sequences of Cycs, Apaf1, Casp9, Casp3a, and Casp3b involved in the mitochondria apo...

journal_title：Frontiers in physiology

authors： Li DD,Ling SC,Wu K,Luo Z

更新日期：2019-08-02 00:00:00

abstract：:The hippocampus is known as a neuronal structure involved in learning, memory and spatial navigation using multi-sensory cues. However, the basic features of its response to acoustic stimuli without any behavioral tasks (conditioning) remains poorly studied. Here, we investigated the CA3 response to auditory stimuli u...

journal_title：Frontiers in physiology

authors： Wang N,Gan X,Liu Y,Xiao Z

更新日期：2017-11-21 00:00:00

abstract：:Epilepsy is one of the most common disorders of the brain. Clinically, to corroborate an epileptic seizure-like symptom and to find the seizure localization, electroencephalogram (EEG) data are often visually examined by a clinical doctor to detect the presence of epileptiform discharges. Epileptiform discharges are t...

journal_title：Frontiers in physiology

authors： Li Q,Gao J,Zhang Z,Huang Q,Wu Y,Xu B

更新日期：2020-08-05 00:00:00

abstract：:The microbes in the gastrointestinal tract are separated from the host by a single layer of intestinal epithelial cells (IECs) that plays pivotal roles in maintaining homeostasis by absorbing nutrients and providing a physical and immunological barrier to potential pathogens. Preservation of homeostasis requires the c...

journal_title：Frontiers in physiology

authors： Burgueño JF,Fritsch J,Santander AM,Brito N,Fernández I,Pignac-Kobinger J,Conner GE,Abreu MT

更新日期：2019-12-12 00:00:00

abstract：:A primary goal of enamel research is to understand and potentially treat or prevent enamel defects related to amelogenesis imperfecta (AI). Rodents are ideal models to assist our understanding of how enamel is formed because they are easily genetically modified, and their continuously erupting incisors display all sta...

journal_title：Frontiers in physiology

authors： Pugach MK,Gibson CW

更新日期：2014-09-17 00:00:00

abstract：:The upcoming exploration missions will imply a much longer duration than any of the missions flown so far. In these missions, physiological adaptation to the new environment leads to changes in different body systems, such as the cardiovascular and musculoskeletal systems, metabolic and neurobehavioral health and immu...

journal_title：Frontiers in physiology

authors： Turroni S,Magnani M,Kc P,Lesnik P,Vidal H,Heer M

更新日期：2020-09-08 00:00:00

abstract：:Objective: This study aims to investigate the effect of astragaloside IV on adipose lipolysis and hepatic gluconeogenesis. Methods: High-fat diet (HFD) feeding induced adipose dysfunction with enhanced endogenous glucose production in mice. The effects of Astragaloside IV on lipolysis and hepatic glucose production we...

journal_title：Frontiers in physiology

authors： Du Q,Zhang S,Li A,Mohammad IS,Liu B,Li Y

更新日期：2018-01-23 00:00:00