Apolipophorin-III Acts as a Positive Regulator of Plasmodium Development in Anopheles stephensi.

abstract：:Renal fibrosis is characterized by progressive accumulation of extracellular matrix (ECM) proteins, resulting in loss of organ function and eventually requiring renal replacement therapy. Unfortunately, no efficacious treatment options are available to halt renal fibrosis and translational models to test pharmacologic...

journal_title：Frontiers in physiology

authors： Stribos EGD,Seelen MA,van Goor H,Olinga P,Mutsaers HAM

更新日期：2017-12-12 00:00:00

abstract：:Several Octopodidae species have a great potential for the diversification of worldwide aquaculture. Unfortunately, the lack of stress-related biomarkers in this taxon results an obstacle for its maintenance in conditions where animal welfare is of paramount relevance. In this study, we made a first approach to uncove...

journal_title：Frontiers in physiology

authors： Barragán-Méndez C,Sobrino I,Marín-Rincón A,Fernández-Boo S,Costas B,Mancera JM,Ruiz-Jarabo I

更新日期：2019-06-25 00:00:00

abstract：:Circadian clocks are endogenous oscillators essential for orchestrating daily rhythms in physiology, metabolism and behavior. While mouse models have been instrumental to elucidate the molecular mechanism of circadian rhythm generation, our knowledge about the molecular makeup of circadian oscillators in humans is sti...

journal_title：Frontiers in physiology

authors： Börding T,Abdo AN,Maier B,Gabriel C,Kramer A

更新日期：2019-05-09 00:00:00

abstract：:Objective: Fatigue is a core feature of functional somatic syndromes (FSS). Fatigue is also prominent in patients with thyroid diseases, which is unsurprising given the role of the hypothalamic-pituitary-thyroid (HPT) axis in regulating physiological energy demands. Research in healthy women has shown that early life ...

journal_title：Frontiers in physiology

authors： Fischer S,Markert C,Strahler J,Doerr JM,Skoluda N,Kappert M,Nater UM

更新日期：2018-05-23 00:00:00

abstract：:To determine the level of hypoxia from which muscle activation (MA) is reduced during incremental exercise to exhaustion (IE), and the role played by PIO2 in this process, ten volunteers (21 ± 2 years) performed four IE in severe acute hypoxia (SAH) (PIO2 = 73 mmHg). Upon exhaustion, subjects were asked to continue ex...

journal_title：Frontiers in physiology

authors： Torres-Peralta R,Losa-Reyna J,Morales-Alamo D,González-Izal M,Pérez-Suárez I,Ponce-González JG,Izquierdo M,Calbet JA

更新日期：2016-08-17 00:00:00

abstract：:Erythropoietin (Epo) is an indispensable erythropoietic hormone primarily produced from renal Epo-producing cells (REPs). Epo production in REPs is tightly regulated in a hypoxia-inducible manner to maintain tissue oxygen homeostasis. Insufficient Epo production by REPs causes renal anemia and anemia associated with c...

journal_title：Frontiers in physiology

authors： Souma T,Suzuki N,Yamamoto M

更新日期：2015-06-03 00:00:00

abstract：:Background: Non-invasive cardiac mapping-also known as Electrocardiographic imaging (ECGi)-is a novel, painless and relatively economic method to map the electrical activation and repolarization patterns of the heart, providing a valuable tool for early identification and diagnosis of conduction abnormalities and arrh...

journal_title：Frontiers in physiology

authors： Perez Alday EA,Whittaker DG,Benson AP,Colman MA

更新日期：2019-04-05 00:00:00

abstract：:As clinicians attempt to understand the underlying reasons for the vulnerability of different regions of the developing brain to injury, it is apparent that little is known as to how hypoxia-ischemia may affect the cerebrovasculature in the developing infant. Most of the research investigating the pathogenesis of peri...

journal_title：Frontiers in physiology

authors： Baburamani AA,Ek CJ,Walker DW,Castillo-Melendez M

更新日期：2012-11-09 00:00:00

abstract：:Short bowel syndrome (SBS) is characterized by severe intestinal malabsorption following restrictive surgery. The objective of this study was to determine the functional contribution of SBS-microbiota after resection. It is well-known that SBS-microbiota displayed specific features with a prevalence of Lactobacillus, ...

journal_title：Frontiers in physiology

authors： Gillard L,Mayeur C,Robert V,Pingenot I,Le Beyec J,Bado A,Lepage P,Thomas M,Joly F

更新日期：2017-04-19 00:00:00

abstract：:Purpose: Aging is associated with changes in muscle energy metabolism. Proton (1H) and phosphorous (31P) magnetic resonance spectroscopy (MRS) has been successfully applied for non-invasive investigation of skeletal muscle metabolism. The aim of this study was to detect differences in adenosine triphosphate (ATP) prod...

journal_title：Frontiers in physiology

authors： Krumpolec P,Klepochová R,Just I,Tušek Jelenc M,Frollo I,Ukropec J,Ukropcová B,Trattnig S,Krššák M,Valkovič L

更新日期：2020-06-29 00:00:00

abstract：:In this study, we analyzed the role of mammalian STE20-like protein kinase 2 (Mst2), a serine-threonine protein kinase, in Lipopolysaccharides (LPS)-mediated inflammation and apoptosis in the H9C2 cardiomyocytes. Mst2 mRNA and protein levels were significantly upregulated in the LPS-treated H9C2 cardiomyocytes. LPS tr...

journal_title：Frontiers in physiology

authors： Tian Y,Song H,Qin W,Ding Z,Zhang Y,Shan W,Jin D

更新日期：2020-08-06 00:00:00

abstract：:Unlike other marine teleosts, the Plotosidae catfishes reportedly have an extra-branchial salt secreting dendritic organ (DO). Salinity acclimation [brackishwater (BW) 3aaa, seawater (SWcontrol) 34aaa, and hypersaline water (HSW) 60aaa] for 14 days was used to investigate the osmoregulatory abilities of Plotosus linea...

journal_title：Frontiers in physiology

authors： Malakpour Kolbadinezhad S,Coimbra J,Wilson JM

更新日期：2018-07-03 00:00:00

abstract：:Several studies have demonstrated an acute and chronic increase of brain-derived neurotrophic factor (BDNF) in relation to different types of physical exercise. Currently, many individuals seek physical training strategies that present different types of stimulation and volume/intensity. Thus, the extreme conditioning...

journal_title：Frontiers in physiology

authors： Pereira ES,Krause Neto W,Calefi AS,Georgetti M,Guerreiro L,Zocoler CAS,Gama EF

更新日期：2018-07-03 00:00:00

abstract：:The mechanisms of atrial fibrillation (AF) are a challenging research topic. The rotor hypothesis states that the AF is sustained by a reentrant wave that propagates around an unexcited core. Cardiac tissue heterogeneities, both structural and cellular, play an important role during fibrillatory dynamics, so that the ...

journal_title：Frontiers in physiology

authors： Ugarte JP,Tobón C,Lopes AM,Machado JAT

更新日期：2018-07-24 00:00:00

abstract：:Transport processes between aquaculture facilities activate the stress response in fish. To deal with these situations, the hypothalamic-pituitary-interrenal (HPI) axis releases cortisol, leading to an increase in circulating energy resources to restore homeostasis. However, if the allostatic load generated exceeds fi...

journal_title：Frontiers in physiology

authors： Jerez-Cepa I,Fernández-Castro M,Del Santo O'Neill TJ,Martos-Sitcha JA,Martínez-Rodríguez G,Mancera JM,Ruiz-Jarabo I

更新日期：2019-05-31 00:00:00

abstract：:Advances in high-performance computing are enabling a new generation of software tools that employ computational modeling for surgical planning. Surgical management of laryngeal paralysis is one area where such computational tools could have a significant impact. The current paper describes a comprehensive effort to d...

journal_title：Frontiers in physiology

authors： Mittal R,Zheng X,Bhardwaj R,Seo JH,Xue Q,Bielamowicz S

更新日期：2011-05-02 00:00:00

abstract：:Alcoholic liver disease (ALD) encompasses hepatic steatosis, which may progress to alcoholic hepatitis, fibrosis, and cirrhosis. It remains a leading cause of morbidity and mortality in the US and worldwide. The severity of liver disease correlates with plasma levels of bacterial products in patients, and experimental...

journal_title：Frontiers in physiology

authors： Hartmann P,Chen WC,Schnabl B

更新日期：2012-10-11 00:00:00

abstract：:This study was designed to investigate whether oxidative stress, nitric oxide (NO) deficiency and/or endothelial dysfunction (ED) are present in young borderline hypertensive rats (BHR) and whether these pathologies can be causally involved in the initiation of blood pressure (BP) increases. Additionally, we tested th...

journal_title：Frontiers in physiology

authors： Bernatova I,Puzserova A,Balis P,Sestakova N,Horvathova M,Kralovicova Z,Zitnanova I

更新日期：2018-08-29 00:00:00

abstract：:Cycling test such Wingate anaerobic test (WAnT) is used to measure anaerobic power (AP), but not anaerobic capacity (AC, i.e., the metabolic energy demand). However, in sports that do not involve cycling movements (Karate), the continuous jump for 30 s (vertical jumps for 30 s) has been extensively used to measure ana...

journal_title：Frontiers in physiology

authors： Čular D,Ivančev V,Zagatto AM,Milić M,Beslija T,Sellami M,Padulo J

更新日期：2018-05-15 00:00:00

abstract：:Background and Objective: It is widely accepted that there is an association between chronic obstructive pulmonary disease (COPD) and periodontitis. However, whether the periodontal status of the COPD patients is worse than that of the non-COPD subjects is seldom assessed. The findings currently available are inconsis...

journal_title：Frontiers in physiology

authors： Shi Q,Zhang B,Xing H,Yang S,Xu J,Liu H

更新日期：2018-01-25 00:00:00

abstract：:Background: The purpose of this study was to investigate the acute effects of a single oral administration of an essential amino acids enriched mixture (EAA) on myoelectric descriptors of fatigue and maximal force production after a resistance exercise protocol (REP). Methods: Twenty adult males (age: 27 ± 6 years; bo...

journal_title：Frontiers in physiology

authors： Negro M,Segreto V,Barbero M,Cescon C,Castelli L,Calanni L,D'Antona G

更新日期：2018-08-17 00:00:00

abstract：:Sleep inertia, the transitional state of reduced alertness and impaired cognitive performance upon waking, is a safety risk for on-call personnel who can be required to perform critical tasks soon after waking. Sleep inertia countermeasures have previously been investigated; however, none have successfully dissipated ...

journal_title：Frontiers in physiology

authors： Kovac K,Ferguson SA,Paterson JL,Aisbett B,Hilditch CJ,Reynolds AC,Vincent GE

更新日期：2020-04-07 00:00:00

abstract：:The RR-interval time series or tachograms obtained from electrocardiograms have been widely studied since they reflect the cardiac variability, and this is an indicative of the health status of a person. The tachogram can be seen as a highly non-linear and complex time series, and therefore, should be analyzed with no...

journal_title：Frontiers in physiology

authors： Solís-Montufar EE,Gálvez-Coyt G,Muñoz-Diosdado A

更新日期：2020-08-12 00:00:00

abstract：:Characterization of flow properties in cerebral arteries with 1.5 and 3 Tesla MRI is usually limited to large cerebral arteries and difficult to evaluate in the small perforating arteries due to insufficient spatial resolution. In this study, we assessed the feasibility to measure blood flow waveforms in the small len...

journal_title：Frontiers in physiology

authors： Schnerr RS,Jansen JFA,Uludag K,Hofman PAM,Wildberger JE,van Oostenbrugge RJ,Backes WH

更新日期：2017-11-24 00:00:00

abstract：:Ameloblasts are ectoderm-derived cells that produce an extracellular enamel matrix that mineralizes to form enamel. The development and use of immortalized cell lines, with a stable phenotype, is an important contribution to biological studies as it allows for the investigation of molecular activities without the cont...

journal_title：Frontiers in physiology

authors： Sarkar J,Simanian EJ,Tuggy SY,Bartlett JD,Snead ML,Sugiyama T,Paine ML

更新日期：2014-07-25 00:00:00

abstract：Objective:Polycystin-1 (PC-1) is a protein encoded by the gene of polycystic kidney disease-1 (PKD-1). This study was designed to investigate the regulatory mechanisms of PC-1 on phenotypes of aortic vascular smooth muscle cells (VSMCs) and functions of extracellular matrix (ECM) in thoracic aortic dissection (TAD). M...

journal_title：Frontiers in physiology

authors： Zhang J,Liu F,He YB,Zhang W,Ma WR,Xing J,Wang LX

更新日期：2020-09-24 00:00:00

abstract：Introduction:Hypothermia has notable effects on platelets, platelet function, fibrinogen, and coagulation factors. Common laboratory techniques cannot identify those effects, because blood samples are usually warmed to 37°C before analysis and do not fully reflect the in vivo situation. Multiple aspects of the pathophy...

journal_title：Frontiers in physiology

authors： Wallner B,Schenk B,Hermann M,Paal P,Falk M,Strapazzon G,Martini WZ,Brugger H,Fries D

更新日期：2020-07-14 00:00:00

abstract：:Ischemia/reperfusion (I/R) injury induces irreversible oxidative stress damage to the cardiac myocytes. Many studies have revealed that propofol alleviates the important organelle-mediated injury from oxidative stress in vitro. However, it remains unclear whether propofol prevents I/R-induced DNA damage in cardiomyocy...

journal_title：Frontiers in physiology

authors： Zhou D,Zhuang J,Wang Y,Zhao D,Zhao L,Zhu S,Pu J,Yin M,Zhang H,Wang Z,Hong J

更新日期：2019-03-15 00:00:00

abstract：:Caveolae are membrane micro-domains enriched in cholesterol, sphingolipids and caveolins, which are transmembrane proteins with a hairpin-like structure. Caveolae participate in receptor-mediated trafficking of cell surface receptors and receptor-mediated signaling. Furthermore, caveolae participate in clathrin-indepe...

journal_title：Frontiers in physiology

authors： Navarro G,Borroto-Escuela DO,Fuxe K,Franco R

更新日期：2014-09-30 00:00:00

abstract：:Antineoplastic drugs can be associated with several side effects, including cardiovascular toxicity (CTX). Biochemical studies have identified multiple mechanisms of CTX. Chemoterapeutic agents can alter redox homeostasis by increasing the production of reactive oxygen species (ROS) and reactive nitrogen species RNS. ...

journal_title：Frontiers in physiology

authors： Varricchi G,Ameri P,Cadeddu C,Ghigo A,Madonna R,Marone G,Mercurio V,Monte I,Novo G,Parrella P,Pirozzi F,Pecoraro A,Spallarossa P,Zito C,Mercuro G,Pagliaro P,Tocchetti CG

更新日期：2018-03-07 00:00:00