Intestinal Epithelial Cells Respond to Chronic Inflammation and Dysbiosis by Synthesizing H2O2.

abstract：:Determining individual health status is of great importance for a better understanding of life history trade-offs between growth, reproduction, and maintenance. However, existing immunological methods are invasive and therefore not suitable for investigating health status in wild populations. Thus, there is an urgent ...

journal_title：Frontiers in physiology

authors： Behringer V,Stevens JM,Leendertz FH,Hohmann G,Deschner T

更新日期：2017-02-06 00:00:00

abstract：:Background: A range of computational methods that rely on the analysis of genome-wide expression datasets have been developed and successfully used for drug repositioning. The success of these methods is based on the hypothesis that introducing a factor (in this case, a drug molecule) that could reverse the disease ge...

journal_title：Frontiers in physiology

authors： Zheng T,Ni Y,Li J,Chow BKC,Panagiotou G

更新日期：2017-09-28 00:00:00

abstract：:As a biomaterial, chitosan has been widely used in tissue engineering, wound healing, drug delivery, and other biomedical applications. It can be formulated in a variety of forms, such as powder, film, sphere, gel, and fiber. These features make chitosan an almost ideal biomaterial in cell culture applications, and ce...

journal_title：Frontiers in physiology

authors： Gao W,Lai JC,Leung SW

更新日期：2012-08-21 00:00:00

abstract：AIM:The signaling pathways involved in the regulation of cardiac GLUT4 translocation/glucose uptake and CD36 translocation/long-chain fatty acid uptake are not fully understood. We compared in heart/muscle-specific PKC-λ knockout mice the roles of atypical PKCs (PKC-ζ and PKC-λ) in regulating cardiac glucose and fatty ...

journal_title：Frontiers in physiology

authors： Habets DD,Luiken JJ,Ouwens M,Coumans WA,Vergouwe M,Maarbjerg SJ,Leitges M,Bonen A,Richter EA,Glatz JF

更新日期：2012-09-11 00:00:00

abstract：:Temperature is an important abiotic factor that drives the evolution of ectotherms owing to its pervasive effects at all levels of organization. Although a species' thermal tolerance is environmentally driven within a spatial cline, it may be constrained over time due to differential phylogenetic inheritance. At the l...

journal_title：Frontiers in physiology

authors： Faria SC,Bianchini A,Lauer MM,Zimbardi ALRL,Tapella F,Romero MC,McNamara JC

更新日期：2020-04-24 00:00:00

abstract：:Human pluripotent stem cells (hPSCs) represent a new and exciting field in modern medicine, now the focus of many researchers and media outlets. The hype is well-earned because of the potential of stem cells to contribute to disease modeling, drug screening, and even therapeutic approaches. In this review, we focus fi...

journal_title：Frontiers in physiology

authors： Martinez Y,Dubois-Dauphin M,Krause KH

更新日期：2012-03-19 00:00:00

abstract：:Respiratory sensory gating function has been found decreased by induced negative emotion in healthy adults. The increased ratio of the respiratory-related evoked potential (RREP) N1 peak amplitude for the second occlusion (S2) vs. the first occlusion (S1), S2/S1, is indicative of such decreased respiratory sensory gat...

journal_title：Frontiers in physiology

authors： Chan PY,Cheng CH,Jhu YJ,Chen CL,von Leupoldt A

更新日期：2016-02-16 00:00:00

abstract：:Objective: Chronic hypoxia causes pulmonary vasoconstriction leading to pulmonary hypertension and right ventricular hypertrophy. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthesis; its level increases in hypoxia (HX) concomitantly with reduced activity of dimethylarginine dim...

journal_title：Frontiers in physiology

authors： Hannemann J,Glatzel A,Hillig J,Zummack J,Schumacher U,Lüneburg N,Harbaum L,Böger R

更新日期：2020-11-12 00:00:00

abstract：:This paper introduces the use of low frequencies forced oscillation technique (FOT) in the presence of breathing signal. The hypothesis tested is to evaluate the sensitivity of FOT to various degrees of obstruction in COPD patients. The measurements were performed in the frequency range 0-2 Hz. The use of FOT to evalu...

journal_title：Frontiers in physiology

authors： Ghita M,Copot D,Ghita M,Derom E,Ionescu C

更新日期：2019-11-19 00:00:00

abstract：:Neural crest (NC) cells are multipotent embryonic cells that form melanocytes, craniofacial bone and cartilage, and the peripheral nervous system in vertebrates. NC cells express many cadherin proteins, which control their specification, epithelial to mesenchymal transition (EMT), migration, and mesenchymal to epithel...

journal_title：Frontiers in physiology

authors： Manohar S,Camacho-Magallanes A,Echeverria C Jr,Rogers CD

更新日期：2020-10-30 00:00:00

abstract：:We examined how systemic blockade of type 1 angiotensin (AT(1)-) receptors affects reflex control of the circulation and the kidney. In conscious rabbits, the effects of candesartan on responses of systemic and renal hemodynamics and renal excretory function to acute hypoxia, mild hemorrhage, and plasma volume expansi...

journal_title：Frontiers in physiology

authors： Xu TB,Eppel GA,Head GA,Evans RG

更新日期：2011-07-19 00:00:00

abstract：:The hippocampus is known as a neuronal structure involved in learning, memory and spatial navigation using multi-sensory cues. However, the basic features of its response to acoustic stimuli without any behavioral tasks (conditioning) remains poorly studied. Here, we investigated the CA3 response to auditory stimuli u...

journal_title：Frontiers in physiology

authors： Wang N,Gan X,Liu Y,Xiao Z

更新日期：2017-11-21 00:00:00

abstract：:Insect β-1,3-glucanases belong to Glycoside Hydrolase Family 16 (GHF16) and are involved in digestion of detritus and plant hemicellulose. In this work, we investigated the role of GHF16 genes in Aedes aegypti larvae, due to their detritivore diet. Aedes aegypti genome has six genes belonging to GHF16 (Aae GH16.1 - Aa...

journal_title：Frontiers in physiology

authors： Souza RS,Gama MDVF,Schama R,Lima JBP,Diaz-Albiter HM,Genta FA

更新日期：2019-02-28 00:00:00

abstract：:Ameloblasts are ectoderm-derived cells that produce an extracellular enamel matrix that mineralizes to form enamel. The development and use of immortalized cell lines, with a stable phenotype, is an important contribution to biological studies as it allows for the investigation of molecular activities without the cont...

journal_title：Frontiers in physiology

authors： Sarkar J,Simanian EJ,Tuggy SY,Bartlett JD,Snead ML,Sugiyama T,Paine ML

更新日期：2014-07-25 00:00:00

abstract：:Teeth and dentitions contain many morphological characters which give them a particularly important weight in comparative anatomy, systematics, physiology and ecology. As teeth are organs that contain the hardest mineralized tissues vertebrates can produce, their fossil remains are abundant and the study of their anat...

journal_title：Frontiers in physiology

authors： Bertin TJC,Thivichon-Prince B,LeBlanc ARH,Caldwell MW,Viriot L

更新日期：2018-11-21 00:00:00

abstract：:Patients undergoing hyperbaric oxygen therapy and divers engaged in underwater activity are at risk of central nervous system oxygen toxicity. An algorithm for predicting CNS oxygen toxicity in active underwater diving has been published previously, but not for humans at rest. Using a procedure similar to that employe...

journal_title：Frontiers in physiology

authors： Aviner B,Arieli R,Yalov A

更新日期：2020-08-17 00:00:00

abstract：:In the quest for a viable non-gravity dependent method to "lift weights" in space, our laboratory introduced iso-inertial resistance (YoYo™) exercise using spinning flywheel(s), more than 25 years ago. After being thoroughly tested in individuals subjected to various established spaceflight analogs, a multi-mode YoYo™...

journal_title：Frontiers in physiology

authors： Tesch PA,Fernandez-Gonzalo R,Lundberg TR

更新日期：2017-04-27 00:00:00

abstract：:Circulating microRNAs have proven to be reliable biomarkers, due to their high stability, both in vivo in the circulation, and ex vivo during sample preparation and storage. Small nucleolar RNAs (snoRNAs) are a different type of small non-coding RNAs that can also be reliably measured in plasma, but have only been stu...

journal_title：Frontiers in physiology

authors： Håkansson KEJ,Sollie O,Simons KH,Quax PHA,Jensen J,Nossent AY

更新日期：2018-08-22 00:00:00

abstract：:One of the central issues of the whole process of biogenesis is how to understand the progressive constitution of a large (in spatial and temporal terms) system that transcends the individual sphere of proto-metabolic organizations and includes collective networks, both synchronous (i.e., proto-ecosystem webs) and asy...

journal_title：Frontiers in physiology

authors： Moreno A

更新日期：2019-09-24 00:00:00

abstract：:Human induced pluripotent stem cell derived cardiomyocytes (iPSC-CMs) have applications in disease modeling, cell therapy, drug screening and personalized medicine. Computational models can be used to interpret experimental findings in iPSC-CMs, provide mechanistic insights, and translate these findings to adult cardi...

journal_title：Frontiers in physiology

authors： Lei CL,Wang K,Clerx M,Johnstone RH,Hortigon-Vinagre MP,Zamora V,Allan A,Smith GL,Gavaghan DJ,Mirams GR,Polonchuk L

更新日期：2017-12-12 00:00:00

abstract：:During formation of the secondary palate in mammalian embryos, two vertically oriented palatal shelves rapidly elevate into a horizontal position above the tongue, meet at the midline, and fuse to form a single entity. Previous observations suggested that elevation occurs by a simple 90° rotation of the palatal shelve...

journal_title：Frontiers in physiology

authors： Chiquet M,Blumer S,Angelini M,Mitsiadis TA,Katsaros C

更新日期：2016-09-07 00:00:00

abstract：:Many animals use a diverse repertoire of complex acoustic signals to convey different types of information to other animals. The information in each vocalization therefore must be coded by neurons in the auditory system. One way in which the auditory system may discriminate among different vocalizations is by having h...

journal_title：Frontiers in physiology

authors： Dimitrov AG,Cummins GI,Mayko ZM,Portfors CV

更新日期：2014-04-16 00:00:00

abstract：:Muscle fatigue is the decline in performance of muscles observed during periods of intense activity. ATP consumption exceeds production during intense activity and there are multiple changes in intracellular metabolites which may contribute to the changes in crossbridge activity. It is also well-established that a red...

journal_title：Frontiers in physiology

authors： Allen DG,Trajanovska S

更新日期：2012-12-11 00:00:00

abstract：:The age at which women experience their first pregnancy has increased throughout the decades. Pregnancy has an important influence on maternal short- and long-term cardiovascular outcomes. Pregnancy at an advanced maternal age increases maternal risk of gestational diabetes, preeclampsia, placenta previa and caesarian...

journal_title：Frontiers in physiology

authors： Morton JS,Care AS,Kirschenman R,Cooke CL,Davidge ST

更新日期：2017-06-30 00:00:00

abstract：:Natural reward is an essential element of any organism's ability to adapt to environmental variation. Its underlying circuits and mechanisms guide the learning process as they help associate an event, or cue, with the perception of an outcome's value. More generally, natural reward serves as the fundamental generator ...

journal_title：Frontiers in physiology

authors： Datta U,van Staaden M,Huber R

更新日期：2018-05-14 00:00:00

abstract：:Background and Objective: It is widely accepted that there is an association between chronic obstructive pulmonary disease (COPD) and periodontitis. However, whether the periodontal status of the COPD patients is worse than that of the non-COPD subjects is seldom assessed. The findings currently available are inconsis...

journal_title：Frontiers in physiology

authors： Shi Q,Zhang B,Xing H,Yang S,Xu J,Liu H

更新日期：2018-01-25 00:00:00

abstract：:Corpus luteum (CL) is a transient endocrine tissue that produces progesterone for maintaining pregnancy in mammals. In addition, the regression of CL is necessary for the initiation of the estrous cycle. Extensive research has shown that the prostaglandin F2α (PGF2α) induces the regression of CL in ruminants. However,...

journal_title：Frontiers in physiology

authors： Wen X,Liu L,Li S,Lin P,Chen H,Zhou D,Tang K,Wang A,Jin Y

更新日期：2020-09-11 00:00:00

abstract：:Heat acclimation by post-exercise hot water immersion (HWI) on six consecutive days reduces thermal strain and improves exercise performance during heat stress. However, the retention of adaptations by this method remains unknown. Typically, adaptations to short-term, exercise-heat-acclimation (<7 heat exposures) deca...

journal_title：Frontiers in physiology

authors： Zurawlew MJ,Mee JA,Walsh NP

更新日期：2019-08-28 00:00:00

abstract：:In the present study, we examined the effects of central administration of Urotensin II on blood pressure, heart rate, and baroreceptor heart rate reflexes in conscious normotensive rabbits. Preliminary operations were undertaken to implant a balloon cuff on the inferior vena cava for baroreflex assessments and to imp...

journal_title：Frontiers in physiology

authors： Lim K,Sata Y,Jackson KL,Burke SL,Head GA

更新日期：2017-02-23 00:00:00

abstract：:To date, there has been no study on the long-term effects of resistance exercise on sarcopenia and obesity indices for people with sarcopenia. The present study thus aimed to determine the effect of 18 months of periodized, high-velocity/intensity/effort progressive resistance training (HIT-RT) on body composition and...

journal_title：Frontiers in physiology

authors： Kemmler W,Kohl M,Fröhlich M,Engelke K,von Stengel S,Schoene D

更新日期：2020-08-27 00:00:00