Time computations in anuran auditory systems.

abstract：:We investigate analytically the production of entropy during a breathing cycle in healthy and diseased lungs. First, we calculate entropy production in healthy lungs by applying the laws of thermodynamics to the well-known transpulmonary pressure-volume (P-V) curves of the lung under the assumption that lung tissue be...

journal_title：Frontiers in physiology

authors： Oliveira CL,Araújo AD,Bates JH,Andrade JS Jr,Suki B

更新日期：2016-03-01 00:00:00

abstract：:The human brain is constantly active and even small limitations to cerebral blood flow (CBF) may be critical for preserving oxygen and substrate supply, e.g., during exercise and hypoxia. Exhaustive exercise evokes a competition for the supply of oxygenated blood between the brain and the working muscles, and inabilit...

journal_title：Frontiers in physiology

authors： Kim YS,van der Ster BJP,Brassard P,Secher NH,van Lieshout JJ

更新日期：2021-01-15 00:00:00

abstract：:The year 2002 marked the tercentenary of Antonie van Leeuwenhoek's discovery of desiccation tolerance in animals. This remarkable phenomenon to sustain 'life' in the absence of water can be revived upon return of hydrating conditions. Today, coping with climate change-related factors, especially temperature-humidity i...

journal_title：Frontiers in physiology

authors： Thorat L,Nath BB

更新日期：2018-12-21 00:00:00

abstract：:Activation of autonomic neural pathways by chronic hypertensive stimuli plays a significant role in pathogenesis of hypertension. Here, we proposed that even a single acute hypertensive stimulus will activate neural and immune pathways that may be important in initiation of memory imprinting seen in chronic hypertensi...

journal_title：Frontiers in physiology

authors： Zubcevic J,Santisteban MM,Perez PD,Arocha R,Hiller H,Malphurs WL,Colon-Perez LM,Sharma RK,de Kloet A,Krause EG,Febo M,Raizada MK

更新日期：2017-08-31 00:00:00

abstract：:Obstructive sleep apnea (OSA), manifested by exposure to chronic intermittent hypoxia (CIH) and excess production of reactive oxygen species (ROS) in the airways, is associated with hyperreactive airway diseases. ROS, particularly when created by NADPH oxidase, are known to sensitize lung vagal C fibers (LVCFs), which...

journal_title：Frontiers in physiology

authors： Yang CH,Zhuang WL,Shen YJ,Lai CJ,Kou YR

更新日期：2016-05-09 00:00:00

abstract：:The cell-division cycle (CDC) is driven by cyclin-dependent kinases (CDKs). Mathematical models based on molecular networks, as revealed by molecular and genetic studies, have reproduced the oscillatory behavior of CDK activity. Thus, one basic system for representing the CDC is a biochemical oscillator (CDK oscillato...

journal_title：Frontiers in physiology

authors： Arata Y,Takagi H

更新日期：2019-08-19 00:00:00

abstract：:Sarcopenia is defined as the progressive loss of muscle mass with age, and poses a serious threat to the physiological and psychological health of the elderly population with consequential economic and social burdens. Chronic low-grade inflammation plays a central role in the development of sarcopenia such that it alt...

journal_title：Frontiers in physiology

authors： Xia Z,Cholewa J,Zhao Y,Shang HY,Yang YQ,Araújo Pessôa K,Su QS,Lima-Soares F,Zanchi NE

更新日期：2017-06-22 00:00:00

abstract：:Background: An amount of cognition decline is normal with aging; however, intrinsic and extrinsic risk factors may exacerbate it, affecting social and occupational tasks. Masticatory dysfunction (MD), as a general term, refers to an impairment in the masticatory function triggered by a structural factor, such as tooth...

journal_title：Frontiers in physiology

authors： Alvarenga MOP,Ferreira RO,Magno MB,Fagundes NCF,Maia LC,Lima RR

更新日期：2019-07-03 00:00:00

abstract：:Defects in mitochondrial ribosomal proteins (MRPs) cause various diseases in humans. Because of the essential role of MRPs in synthesizing the essential subunits of oxidative phosphorylation (OXPHOS) complexes, identifying all of the protein components involved in the mitochondrial translational machinery is critical....

journal_title：Frontiers in physiology

authors： Koc EC,Cimen H,Kumcuoglu B,Abu N,Akpinar G,Haque ME,Spremulli LL,Koc H

更新日期：2013-07-30 00:00:00

abstract：:The present study aims (1) to evaluate ratings of perceived exertion (RPE) and corresponding intensities during a maximal graded cycling test and (2) to determine the effects of 6 weeks of supramaximal cycling exercise (SCE) intervention on RPE and associated physiological factors in young and older sedentary groups. ...

journal_title：Frontiers in physiology

authors： Jabbour G,Majed L

更新日期：2018-10-25 00:00:00

abstract：:Loss of skeletal muscle myofibrillar protein with disease and/or inactivity can severely deteriorate muscle strength and function. Strategies to counteract wasting of muscle myofibrillar protein are therefore desirable and invite for considerations on the potential superiority of specific modes of resistance exercise ...

journal_title：Frontiers in physiology

authors： Rindom E,Vissing K

更新日期：2016-11-17 00:00:00

abstract：:Background: Constant blood flow despite changes in blood pressure, a phenomenon called autoregulation, has been demonstrated for various organ systems. We hypothesized that by changing hydrostatic pressures in peripheral arteries, we can establish these limits of autoregulation in peripheral arteries based on local pu...

journal_title：Frontiers in physiology

authors： Tripathi A,Obata Y,Ruzankin P,Askaryar N,Berkowitz DE,Steppan J,Barodka V

更新日期：2017-11-02 00:00:00

abstract：:Hepatocellular carcinomas (HCCs) have different etiology and heterogenic genomic alterations lead to high complexity. The molecular features of HCC have largely been studied by gene expression and proteome profiling focusing on the correlations between the expression of specific markers and clinical data. Integration ...

journal_title：Frontiers in physiology

authors： D'Alessandro LA,Meyer R,Klingmüller U

更新日期：2013-02-25 00:00:00

abstract：:Domestic pig molars provide an interesting system to study the biomineralization process. The large size, thick enamel and complex crown morphology make pig molars relatively similar to human molars. However, compared to human molars, pig molars develop considerably faster. Here we use microCT to image the developing ...

journal_title：Frontiers in physiology

authors： Sova SS,Tjäderhane L,Heikkilä PA,Jernvall J

更新日期：2018-02-09 00:00:00

abstract：:Periventricular-intraventricular hemorrhages (PIVH) and (diffuse) white matter injury (WMI) are the most important acquired brain lesions of the very and extremely prematurely born neonate. Both carry a high risk for death or adverse neurodevelopmental outcome. The first part of the review discusses the standard of ca...

journal_title：Frontiers in physiology

authors： van Bel F,Vaes J,Groenendaal F

更新日期：2019-03-20 00:00:00

abstract：:As arteries become stiffer with aging, reflected waves move faster and augment late systolic pressure. Few studies have described the age-related changes in both peripheral and central systolic blood pressures in populations. We investigated the age dependency of peripheral (pSBP) and central (cSBP) systolic pressure ...

journal_title：Frontiers in physiology

authors： Wojciechowska W,Li Y,Stolarz-Skrzypek K,Kawecka-Jaszcz K,Staessen JA,Wang JG,European Project on Genes in Hypertension and the JingNing Study Investigators.

更新日期：2012-06-15 00:00:00

abstract：:The gut microbiome is extremely important for maintaining homeostasis with host intestinal epithelial, neuronal, and immune cells and this host-microbe interaction is critical during times of stress or disease. Environmental, nutritional, and cognitive stress are just a few factors known to influence the gut microbiot...

journal_title：Frontiers in physiology

authors： Pearce SC,Coia HG,Karl JP,Pantoja-Feliciano IG,Zachos NC,Racicot K

更新日期：2018-11-12 00:00:00

abstract：:Inflammation-induced impaired function of vascular endothelium may cause leakage of plasma proteins that can lead to edema. Proteins may leave the vascular lumen through two main paracellular and transcellular pathways. As the first involves endothelial cell (EC) junction proteins and the second caveolae formation, th...

journal_title：Frontiers in physiology

authors： Muradashvili N,Tyagi R,Lominadze D

更新日期：2012-05-31 00:00:00

abstract：:Apelin is the endogenous ligand of APJ, the orphan G protein-coupled receptor. The apelin-APJ signal transduction pathway is widely expressed in the cardiovascular system and is an important factor in cardiovascular homeostasis. This signal transduction pathway has long been related to diseases with high morbidity in ...

journal_title：Frontiers in physiology

authors： Zhou Y,Wang Y,Qiao S,Yin L

更新日期：2017-12-12 00:00:00

abstract：:Environmental hypoxia represents a major physiological challenge for Eriocheir sinensis and Palaemonetes sinensis and is a severe problem in aquaculture. Therefore, understanding the metabolic response mechanisms of E. sinensis and P. sinensis, which are economically important species, to environmental hypoxia and reo...

journal_title：Frontiers in physiology

authors： Bao J,Li X,Yu H,Jiang H

更新日期：2018-11-06 00:00:00

abstract：:Objective: Despite the improvement in ventricular assist device (VAD) therapy in adults and in adolescents, in infant population only Berlin Heart EXCOR (BHE) is licensed as long term VAD to bridge children to Heart Transplantation (HTx). Particularly demanding in terms of morbidity and mortality are smallest patients...

journal_title：Frontiers in physiology

authors： Di Molfetta A,Gandolfo F,Filippelli S,Perri G,Di Chiara L,Iacobelli R,Adorisio R,Favia I,Rizza A,Testa G,Di Nardo M,Amodeo A

更新日期：2016-12-06 00:00:00

abstract：:Much effort has gone into elucidating control of the body by the brain, less so the role of the body in controlling the brain. This essay develops the idea that the brain does a great deal of work in the service of behavior that is controlled by the body, a blue-collar role compared to the white-collar control exercis...

journal_title：Frontiers in physiology

authors： Van Orden G,Hollis G,Wallot S

更新日期：2012-06-18 00:00:00

abstract：:Pesticide resistance is a serious problem that poses a major challenge to pest control. One of the most potent resistance mechanisms is the overexpression of genes coding for detoxification enzymes. The expression of detoxification genes is regulated by a series of transcription factors. Previous studies have revealed...

journal_title：Frontiers in physiology

authors： Tang GH,Xiong Y,Liu Y,Song ZH,Yang Y,Shen GM,Wang JJ,Jiang HB

更新日期：2019-08-20 00:00:00

abstract：:Skeletal muscle is a plastic tissue that undergoes cellular and metabolic adaptations under conditions of increased contractile activity such as exercise. Using adult zebrafish as an exercise model, we previously demonstrated that swimming training stimulates hypertrophy and vascularization of fast muscle fibers, cons...

journal_title：Frontiers in physiology

authors： Rovira M,Arrey G,Planas JV

更新日期：2017-12-18 00:00:00

abstract：:Atherosclerosis is considered as a chronic disease of arterial wall, with a strong contribution of inflammation. Dendritic cells (DCs) play a crucial role in the initiation of proatherogenic inflammatory response. Mature DCs present self-antigens thereby supporting differentiation of naïve T cells to effector cells th...

journal_title：Frontiers in physiology

authors： Chistiakov DA,Sobenin IA,Orekhov AN,Bobryshev YV

更新日期：2014-05-27 00:00:00

abstract：:Southeast Asian Ovalocytosis results from a heterozygous deletion of 9 amino acids in the erythrocyte anion exchange protein AE1 (band 3). The report of the first successful birth of an individual homozygous for this mutation showed an association with severe dyserythropoietic anemia. Imaging of the proband's erythroc...

journal_title：Frontiers in physiology

authors： Flatt JF,Stevens-Hernandez CJ,Cogan NM,Eggleston DJ,Haines NM,Heesom KJ,Picard V,Thomas C,Bruce LJ

更新日期：2020-04-28 00:00:00

abstract：:Regulation of energy homeostasis is fundamental for life. In animal species and humans, the Central Nervous System (CNS) plays a critical role in such regulation by integrating peripheral signals and modulating behavior and the activity of peripheral organs. A precise interplay between CNS and peripheral signals is ne...

journal_title：Frontiers in physiology

authors： Kim JD,Leyva S,Diano S

更新日期：2014-12-09 00:00:00

abstract：:Background: Red yeast rice supplements are broadly accepted as treatment for dyslipidaemia in subjects without high cardiovascular (CV) risk. Their effect on lipid profile is well known, but few data are available on their effect on endothelial function. Objectives: To study the effect of a novel nutraceutical compoun...

journal_title：Frontiers in physiology

authors： Cimaglia P,Vieceli Dalla Sega F,Vitali F,Lodolini V,Bernucci D,Passarini G,Fortini F,Marracino L,Aquila G,Rizzo P,Ferrari R,Campo G

更新日期：2019-03-11 00:00:00

abstract：Background:Angiotensin II (Ang II) could promote the development of atrial fibrosis in atrial fibrillation (AF). Apelin can inhibit the occurrence of myocardial fibrosis. However, the effect of apelin on Ang II-induced atrial fibrosis and subsequent AF still remains unknown. Objective:In the present study, we examined...

journal_title：Frontiers in physiology

authors： Lv W,Zhang L,Cheng X,Wang H,Qin W,Zhou X,Tang B

更新日期：2020-11-19 00:00:00

abstract：:Arboviruses are emerging/reemerging infectious agents worldwide. The factors within this scenario include vector and host population fluctuations, climatic changes, anthropogenic activities that disturb ecosystems, an increase in international flights, human mobility, and genetic mutations that allow spill-over phenom...

journal_title：Frontiers in physiology

authors： Diaz LA,Flores FS,Quaglia A,Contigiani MS

更新日期：2013-01-11 00:00:00