Impact of Gut Microbiota on Host Glycemic Control.

abstract：:Background: Associations between vitiligo and thyroid disorders have been suggested, However, the prevalence of thyroid disorders in vitiligo vary widely. Purpose: To conduct a systematic review and meta-analysis assessing the prevalence of thyroid disorders in patients with vitiligo. Method: The PubMed, Cochrane Libr...

journal_title：Frontiers in endocrinology

authors： Yuan J,Sun C,Jiang S,Lu Y,Zhang Y,Gao XH,Wu Y,Chen HD

更新日期：2019-01-15 00:00:00

abstract：:GPER-1 is a novel membrane sited G protein-coupled estrogen receptor. Clinical studies have shown that patients suffering an estrogen receptor α (ERα)/GPER-1 positive, breast cancer have a lower survival rate than those who have developed ERα-positive/GPER-1 negative tumors. Moreover, absence of GPER-1 improves the pr...

journal_title：Frontiers in endocrinology

authors： Molina L,Bustamante F,Ortloff A,Ramos I,Ehrenfeld P,Figueroa CD

更新日期：2020-09-30 00:00:00

abstract：:Anaplastic thyroid cancer is known to be the most lethal malignancy among endocrine tumors for its extremely limited survival rate after diagnosis. As a result of this poor survival prognosis, multimodal therapy is currently under investigation to address this global concern. In this reported case, the 125I seed impla...

journal_title：Frontiers in endocrinology

authors： Niu Y,Ding Z,Deng X,Guo B,Kang J,Wu B,Fan Y

更新日期：2020-04-22 00:00:00

abstract：:Neuropeptides are the largest group of insect hormones. They are produced in the central and peripheral nervous systems and affect insect development, reproduction, feeding, and behavior. A variety of neuropeptide families have been identified in insects. One of these families is the PBAN/pyrokinin family defined by a...

journal_title：Frontiers in endocrinology

authors： Choi MY,Vander Meer RK

更新日期：2012-02-24 00:00:00

abstract：:Reproductive function is regulated by the secretion of luteinizing hormone (LH) and follicle-stimulating hormone from the pituitary and the steroid hormones from the gonads. The dynamic changes in the levels of the reproductive hormones regulate secondary sex characteristics, gametogenesis, cellular function, and beha...

journal_title：Frontiers in endocrinology

authors： Radovick S,Levine JE,Wolfe A

更新日期：2012-04-09 00:00:00

abstract：:Limb length inequality results from many types of musculoskeletal disorders. Asymmetric weight bearing from a limb length discrepancy of less than 2% can have debilitating consequences such as back problems and early-onset osteoarthritis. Existing treatments include invasive surgeries and/or drug regimens that are oft...

journal_title：Frontiers in endocrinology

authors： Racine HL,Meadows CA,Ion G,Serrat MA

更新日期：2018-06-04 00:00:00

abstract：:Gonadotropin-inhibitory hormone (GnIH) was first identified in the Japanese quail as a hypothalamic neuropeptide inhibitor of gonadotropin secretion. Subsequent studies have shown that GnIH is present in the brains of birds including songbirds, and mammals including humans. The identified avian and mammalian GnIH pept...

journal_title：Frontiers in endocrinology

authors： Ubuka T,Son YL,Tobari Y,Tsutsui K

更新日期：2012-11-28 00:00:00

abstract：:Prostate cancer (PCa) is the major cause of cancer-related death among the male population of Western society, and androgen-deprivation therapy (ADT) represents the first line in PCa treatment. However, although androgen receptor (AR) expression is maintained throughout the various stages of PCa, ADT frequently fails....

journal_title：Frontiers in endocrinology

authors： Di Donato M,Giovannelli P,Cernera G,Di Santi A,Marino I,Bilancio A,Galasso G,Auricchio F,Migliaccio A,Castoria G

更新日期：2015-01-19 00:00:00

abstract：:Estetrol (E4) is a natural human estrogen present at high concentrations during pregnancy. Due to its high oral bioavailability and long plasma half-life, E4 is particularly suitable for therapeutic applications. E4 acts as a selective estrogen receptor (ER) modulator, exerting estrogenic actions on the endometrium or...

journal_title：Frontiers in endocrinology

authors： Giretti MS,Montt Guevara MM,Cecchi E,Mannella P,Palla G,Spina S,Bernacchi G,Di Bello S,Genazzani AR,Genazzani AD,Simoncini T

更新日期：2014-05-26 00:00:00

abstract：:Leptin affects food intake regulation and energy homeostasis in mammals, as opposed to mammals who have a single leptin gene, fish have duplicated leptin gene paralogues. Until now, most functional studies on fish focused on the first reported paralogue without much explanation on specific gene paralogue. This study s...

journal_title：Frontiers in endocrinology

authors： Yuan XC,Liang XF,Cai WJ,Li AX,Huang D,He S

更新日期：2020-08-14 00:00:00

abstract：:RET gene rearrangements (RET/PTCs) represent together with BRAF point mutations the two major groups of mutations involved in papillary thyroid carcinoma (PTC) initiation and progression. In this review, we will examine the mechanisms involved in RET/PTC-induced thyroid cell transformation. In detail, we will summariz...

journal_title：Frontiers in endocrinology

authors： Menicali E,Moretti S,Voce P,Romagnoli S,Avenia N,Puxeddu E

更新日期：2012-05-22 00:00:00

abstract：:Accumulating evidence shows that H2S has physiological functions in various tissues and organs. It includes regulation of neuronal activity, vascular tension, a release of insulin, and protection of the heart, kidney, and brain from ischemic insult. H2S is produced by enzymes from l-cysteine; cystathionine β-synthase,...

journal_title：Frontiers in endocrinology

authors： Shibuya N,Kimura H

更新日期：2013-07-16 00:00:00

abstract：:Graves' disease (GD) is an organ-specific autoimmune disease, and thyrotropin (TSH) receptor (TSHR) is a major autoantigen in this condition. Since the extracellular domain of human TSHR (TSHR-ECD) is shed into the circulation, TSHR-ECD is a preferentially immunogenic portion of TSHR. Both genetic factors and environm...

journal_title：Frontiers in endocrinology

authors： Inaba H,De Groot LJ,Akamizu T

更新日期：2016-08-23 00:00:00

abstract：:Besides aging, a number of non-modifiable lifestyle-related factors, such as smoking, elevated consumption of caffeine and alcohol, stress, agonist sports, chronic exposure to environmental pollutants, and other nutritional habits exert a negative impact on a women's fertility. In particular, metabolic disorders inclu...

journal_title：Frontiers in endocrinology

authors： Silvestris E,Lovero D,Palmirotta R

更新日期：2019-06-07 00:00:00

abstract：Background:For detecting tumor recurrence of medullary thyroid carcinoma (MTC) in the neck, an appropriate frequency and interval of postoperative ultrasonography (US) surveillance remains unclear. This study aimed to assess an appropriate interval and frequency of postoperative neck US surveillance for detecting tumor...

journal_title：Frontiers in endocrinology

authors： Ahn HS,Kim DW,Lee YJ,Lee CY,Kim JH,Choi YJ,Lee S,Ryoo I,Huh JY,Sung JY,Kwak JY,Baek HJ

更新日期：2018-03-15 00:00:00

abstract：:The incidence of type 2 diabetes significantly increases with age. The relevance of this association is dramatically magnified by the concomitant global aging of the population, but the underlying mechanisms remain to be fully elucidated. Here, some recent advances in this field are reviewed at the level of both the p...

journal_title：Frontiers in endocrinology

authors： De Tata V

更新日期：2014-09-03 00:00:00

abstract：:The insulin-like growth factor (IGF) family plays key roles in growth and development. In the cornea, IGF family members have been implicated in proliferation, differentiation, and migration, critical events that maintain a smooth refracting surface that is essential for vision. The IGF family is composed of multiple ...

journal_title：Frontiers in endocrinology

authors： Stuard WL,Titone R,Robertson DM

更新日期：2020-03-03 00:00:00

abstract：:Oxidative stress induced by free fatty acid overload in pancreatic β-cells is a potential contributory factor to dysfunction of insulin secretion and apoptotic cell death. Perilipin 5 (Plin5) has been reported to ameliorate oxidative stress-mediated damage in non-insulin-secreting tissues. We tested the hypothesis tha...

journal_title：Frontiers in endocrinology

authors： Zhu Y,Ren C,Zhang M,Zhong Y

更新日期：2020-03-31 00:00:00

abstract：:Background: Carney complex (CNC) is a rare multiple endocrine neoplasia syndrome with autosomal dominant inheritance. Affected individuals present with mucocutaneous lentigines/blue nevi, cardiac and noncardiac myxomatous tumors, and multiple endocrine tumors. Mutations in PRKAR1A have been identified as genetic cause...

journal_title：Frontiers in endocrinology

authors： Ralser DJ,Strizek B,Kupczyk P,Stoffel-Wagner B,Altengarten J,Müller A,Woelfle J,Gembruch U,Klingmueller D,Merz WM,Paschkowiak-Christes A

更新日期：2020-05-08 00:00:00

abstract：:Background and Purpose: Many imaging studies have reported structure alterations in patients with type 1 diabetes mellitus (T1DM) by using voxel-based morphometry (VBM). Nevertheless, the results reported were inconsistent and had not been reviewed quantitatively. Accordingly, the quantitative meta-analysis which incl...

journal_title：Frontiers in endocrinology

authors： Liu J,Fan W,Jia Y,Su X,Wu W,Long X,Sun X,Liu J,Sun W,Zhang T,Gong Q,Shi H,Zhu Q,Wang J

更新日期：2020-02-13 00:00:00

abstract：:Objective: To study the impact of dose reduction in MDCT images through tube current reduction or sparse sampling on the vertebral bone strength prediction using finite element (FE) analysis for fracture risk assessment. Methods: Routine MDCT data covering lumbar vertebrae of 12 subjects (six male; six female; 74.70 ±...

journal_title：Frontiers in endocrinology

authors： Rayudu NM,Subburaj K,Mei K,Dieckmeyer M,Kirschke JS,Noël PB,Baum T

更新日期：2020-07-28 00:00:00

abstract：:Objective: Prolactin and progesterone are implicated in glucose homeostasis in and outside of pregnancy. However, their associations with gestational diabetes (GDM) risk were not well-understood. This study investigates this question in a prospective and longitudinal cohort. Methods: This is a nested case-control stud...

journal_title：Frontiers in endocrinology

authors： Li M,Song Y,Rawal S,Hinkle SN,Zhu Y,Tekola-Ayele F,Ferrara A,Tsai MY,Zhang C

更新日期：2020-02-27 00:00:00

abstract：:Objective: Circulating free DNA (cfDNA) in general and circulating tumor DNA (ctDNA) in particular is becoming an increasingly used form of liquid biopsy biomarkers. In this study, we are investigating the ability to detect ctDNA from the plasma of pituitary adenoma (PA) patients. Design: Tumor tissue samples were obt...

journal_title：Frontiers in endocrinology

authors： Megnis K,Peculis R,Rovite V,Laksa P,Niedra H,Balcere I,Caune O,Breiksa A,Nazarovs J,Stukens J,Konrade I,Pirags V,Klovins J

更新日期：2019-09-18 00:00:00

abstract：:Somatostatin is highly expressed in mammalian brain and is involved in many brain functions such as motor activity, sleep, sensory, and cognitive processes. Five somatostatin receptors have been described: sst(1), sst(2) (A and B), sst(3), sst(4), and sst(5), all belonging to the G-protein-coupled receptor family. Dur...

journal_title：Frontiers in endocrinology

authors： Martel G,Dutar P,Epelbaum J,Viollet C

更新日期：2012-12-06 00:00:00

abstract：:Background: Consistent evidence have demonstrated that patients with primary aldosteronism (PA) have higher risk of cardiovascular events to patients with essential hypertension (EH). Whether the long-term risk of mortality for PA patients is higher than EH patients is unclear. We aim to compare the long-term mortalit...

journal_title：Frontiers in endocrinology

authors： Meng Z,Dai Z,Huang K,Xu C,Zhang YG,Zheng H,Liu TZ

更新日期：2020-03-10 00:00:00

abstract：:Pregnancy-associated plasma protein-A (PAPP-A) and its homolog PAPP-A2 are enzymes that modulate the availability and mitogenic activity of insulin-like growth factor-I (IGF-I). PAPP-A has been implicated in numerous cancers but reports on PAPP-A2 in malignancy are non-existent. In a prospective observational study of...

journal_title：Frontiers in endocrinology

authors： Hjortebjerg R,Espelund U,Rasmussen TR,Folkersen B,Steiniche T,Georgsen JB,Oxvig C,Frystyk J

更新日期：2020-09-02 00:00:00

abstract：:Polybrominated diphenyl ethers (PBDEs) were used as flame-retardant additives starting 1965 and were recently withdrawn from commerce in North America and Europe. Approximately 1/5 of the total U.S. population were born when environmental concentrations of PBDE plateaued at their maximum. Accumulating evidence suggest...

journal_title：Frontiers in endocrinology

authors： Khalil A,Cevik SE,Hung S,Kolla S,Roy MA,Suvorov A

更新日期：2018-09-20 00:00:00

abstract：:Background: Slow-wave activity (SWA) in non-rapid eye movement (NREM) sleep, obtained by spectral analysis of the electroencephalogram, is a marker of the depth or intensity of NREM sleep. Higher levels of SWA are associated with lower arousability during NREM sleep and protect against sleep fragmentation. Multiple st...

journal_title：Frontiers in endocrinology

authors： Morselli LL,Temple KA,Leproult R,Ehrmann DA,Van Cauter E,Mokhlesi B

更新日期：2018-07-12 00:00:00

abstract：:Besides its interest for diagnosis, the finding of an elevated serum AMH level in PCOS has open major pathophysiological issues. This review addresses the three most important issues: 1- the role of AMH in the disturbed folliculogenesis of PCOS; 2- the role of AMH in the gonadotropin dysregulation of PCOS and 3- the r...

journal_title：Frontiers in endocrinology

authors： Dewailly D,Barbotin AL,Dumont A,Catteau-Jonard S,Robin G

更新日期：2020-09-09 00:00:00

abstract：Objective:Both vitamin D and K2 are involved in a number of metabolic processes, including bone metabolism; however, associations between the vitamins are not fully understood. The aim of the study was to evaluate serum concentrations of 25-hydroxyvitamin D [25(OH)D] in adult patients receiving long-term acenocoumarol ...

journal_title：Frontiers in endocrinology

authors： Sawicka-Powierza J,Konstantynowicz J,Jablonska E,Zelazowska-Rutkowska B,Jelski W,Abramowicz P,Sasinowski C,Chlabicz S

更新日期：2018-05-04 00:00:00