Effect of Sublethal Doses of Imidacloprid on the Biological Performance of Aphid Endoparasitoid Aphidius gifuensis (Hymenoptera: Aphidiidae) and Influence on Its Related Gene Expression.


:The integrated pest management (IPM) strategy was developed and used in combination with pesticides and beneficial biological control agents. To further develop IPM efficiency, it is important to evaluate the side effects of pesticides on biological control agents. Aphidius gifuensis is one of the most important aphid natural enemies and has been successfully used to control Myzys persicae and other aphid species. Imidacloprid (IMD) is a popular pesticide used worldwide and is highly toxic to non-target arthropods. Here, we investigated the short-term sublethal toxicity of IMD in Aphidius gifuensis and its impact on the biological performance and gene expression of this parasitoid. We found that sublethal IMD doses had a significant negative effect on the life history traits of female A. gifuensis, including shortening the lifespan and lowering parasitic capacity. Moreover, exposure to sublethal IMD also adversely affected the response of A. gifuensis to aphid-infested plant volatiles. Based on the transcriptome analysis, we found that the exposure to sublethal IMD doses significantly affected expression of genes involved in the central nervous system, energy metabolism, olfactory, and detoxification system of A. gifuensis. RT-qPCR also revealed that short term expose to sublethal IMD doses significantly induced the gene expression of genes related to the central nervous system (nAChRa7, nAChRa9, TbH, OAR1, NFR, TYR, and DAR1), olfactory system (OR28 and IR8a1), and detoxification system (CYP49p3, CYP6a2, and POD), while it suppressed the expression of genes involved in the central nervous system (nAChRa4 and nAChRb1), olfactory system (Orco1, IR8a2, and GR1), and detoxification system (GST2). Furthermore, exposure to sublethal doses of IMD also significantly increased the activities of CarEs and POD, whereas we observed no influence on the activities of CAT, GST, and SOD. Our results indicate that sublethal IMD doses might adversely affect the biological performance of A. gifuensis by altering gene expression related to the function of olfactory, nervous, energy metabolism, and detoxification systems. Thus, how the use of pesticides directly affect insect population should be considered when used in conjunction with natural pest parasitoids in IPM strategies.


Front Physiol


Frontiers in physiology


Kang ZW,Liu FH,Pang RP,Tian HG,Liu TX




Has Abstract


2018-12-11 00:00:00








  • On the Use of the Repeated-Sprint Training in Hypoxia in Tennis.

    abstract:Purpose:To examine physiological and technical responses to repeated-sprint training in normobaric hypoxia at ∼3,000 m (RSH, n = 11) or in normoxia (RSN, n = 11) compared to a control group (CON, n = 8) in well-trained tennis players. Participants were 28.8 ± 5.9 years old without any previous experience of training in...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Brechbuhl C,Brocherie F,Willis SJ,Blokker T,Montalvan B,Girard O,Millet GP,Schmitt L

    更新日期:2020-12-18 00:00:00

  • Entropy Analysis of RR-Time Series From Stress Tests.

    abstract::The RR-interval time series or tachograms obtained from electrocardiograms have been widely studied since they reflect the cardiac variability, and this is an indicative of the health status of a person. The tachogram can be seen as a highly non-linear and complex time series, and therefore, should be analyzed with no...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Solís-Montufar EE,Gálvez-Coyt G,Muñoz-Diosdado A

    更新日期:2020-08-12 00:00:00

  • Damage from dissection is associated with reduced neuro-musclar transmission and gap junction coupling between circular muscle cells of guinea pig ileum, in vitro.

    abstract::Excitatory and inhibitory junction potentials of circular smooth muscle cells in guinea pig ileum and colon are suppressed 30-90 min after setting up in vitro preparations. We have previously shown this "unresponsive" period is associated with a transient loss of dye coupling between smooth muscle cells, which subsequ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Carbone SE,Wattchow DA,Spencer NJ,Hibberd TJ,Brookes SJ

    更新日期:2014-08-22 00:00:00

  • Metabolic Reprogramming of Mouse Bone Marrow Derived Macrophages Following Erythrophagocytosis.

    abstract::Reticuloendothelial macrophages engulf ∼0.2 trillion senescent erythrocytes daily in a process called erythrophagocytosis (EP). This critical mechanism preserves systemic heme-iron homeostasis by regulating red blood cell (RBC) catabolism and iron recycling. Although extensive work has demonstrated the various effects...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Catala A,Youssef LA,Reisz JA,Dzieciatkowska M,Powers NE,Marchetti C,Karafin M,Zimring JC,Hudson KE,Hansen KC,Spitalnik SL,D'Alessandro A

    更新日期:2020-04-30 00:00:00

  • Dietary Capsaicin Improves Glucose Homeostasis and Alters the Gut Microbiota in Obese Diabetic ob/ob Mice.

    abstract::Background: The effects of capsaicin on obesity and glucose homeostasis are still controversial and the mechanisms underlying these effects remain largely unknown. This study aimed to investigate the potential relationship between the regulation of obesity and glucose homeostasis by dietary capsaicin and the alteratio...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Song JX,Ren H,Gao YF,Lee CY,Li SF,Zhang F,Li L,Chen H

    更新日期:2017-08-25 00:00:00

  • Coronary Angiography-Derived Index of Microvascular Resistance.

    abstract::A coronary angiography-derived index of microvascular resistance (caIMR) is proposed for physiological assessment of microvasular diseases in coronary circulation. The aim of the study is to assess diagnostic performance of caIMR, using wire-derived index of microvascular resistance (IMR) as the reference standard. IM...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Ai H,Feng Y,Gong Y,Zheng B,Jin Q,Zhang HP,Sun F,Li J,Chen Y,Huo Y,Huo Y

    更新日期:2020-12-16 00:00:00

  • A Single Angiotensin II Hypertensive Stimulus Is Associated with Prolonged Neuronal and Immune System Activation in Wistar-Kyoto Rats.

    abstract::Activation of autonomic neural pathways by chronic hypertensive stimuli plays a significant role in pathogenesis of hypertension. Here, we proposed that even a single acute hypertensive stimulus will activate neural and immune pathways that may be important in initiation of memory imprinting seen in chronic hypertensi...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Zubcevic J,Santisteban MM,Perez PD,Arocha R,Hiller H,Malphurs WL,Colon-Perez LM,Sharma RK,de Kloet A,Krause EG,Febo M,Raizada MK

    更新日期:2017-08-31 00:00:00

  • A 5-year comparison of marginal bone level following immediate loading of single-tooth implants placed in healed alveolar ridges and extraction sockets in the maxilla.

    abstract:PURPOSE:The aim of present investigation was to evaluate marginal bone level after 5-year follow-up of implants placed in healed ridges and fresh extraction sockets in maxilla with immediate loading protocol. MATERIALS AND METHODS:Thirty-six patients in need of a single-tooth replacement in the anterior maxilla receiv...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Berberi AN,Sabbagh JM,Aboushelib MN,Noujeim ZF,Salameh ZA

    更新日期:2014-01-31 00:00:00

  • Criticality Maximizes Complexity in Neural Tissue.

    abstract::The analysis of neural systems leverages tools from many different fields. Drawing on techniques from the study of critical phenomena in statistical mechanics, several studies have reported signatures of criticality in neural systems, including power-law distributions, shape collapses, and optimized quantities under t...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Timme NM,Marshall NJ,Bennett N,Ripp M,Lautzenhiser E,Beggs JM

    更新日期:2016-09-27 00:00:00

  • Current Perspectives on Tooth Implantation, Attachment, and Replacement in Amniota.

    abstract::Teeth and dentitions contain many morphological characters which give them a particularly important weight in comparative anatomy, systematics, physiology and ecology. As teeth are organs that contain the hardest mineralized tissues vertebrates can produce, their fossil remains are abundant and the study of their anat...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审


    authors: Bertin TJC,Thivichon-Prince B,LeBlanc ARH,Caldwell MW,Viriot L

    更新日期:2018-11-21 00:00:00

  • Bacillus thuringiensis Suppresses the Humoral Immune System to Overcome Defense Mechanism of Plutella xylostella.

    abstract::Background:Plutella xylostella has become a notorious pest of cruciferous crops all over the world. Delta-endotoxins of Bacillus thuringiensis are widely used insecticidal proteins for controlling P. xylostella. However, the interaction mechanism of B. thuringiensis with the immune system of P. xylostella, at the geno...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Li S,Xu X,Shakeel M,Xu J,Zheng Z,Zheng J,Yu X,Zhao Q,Jin F

    更新日期:2018-11-15 00:00:00

  • Resistance Training with Co-ingestion of Anti-inflammatory Drugs Attenuates Mitochondrial Function.

    abstract::Aim: The current study aimed to examine the effects of resistance exercise with concomitant consumption of high vs. low daily doses of non-steroidal anti-inflammatory drugs (NSAIDs) on mitochondrial oxidative phosphorylation in skeletal muscle. As a secondary aim, we compared the effects of eccentric overload with con...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Cardinale DA,Lilja M,Mandić M,Gustafsson T,Larsen FJ,Lundberg TR

    更新日期:2017-12-19 00:00:00

  • Hypothesis and theory: mechanical instabilities and non-uniformities in hereditary sarcomere myopathies.

    abstract::Familial hypertrophic cardiomyopathy (HCM), due to point mutations in genes for sarcomere proteins such as myosin, occurs in 1/500 people and is the most common cause of sudden death in young individuals. Similar mutations in skeletal muscle, e.g., in the MYH7 gene for slow myosin found in both the cardiac ventricle a...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Månsson A

    更新日期:2014-09-15 00:00:00

  • Central nociceptive sensitization vs. spinal cord training: opposing forms of plasticity that dictate function after complete spinal cord injury.

    abstract::The spinal cord demonstrates several forms of plasticity that resemble brain-dependent learning and memory. Among the most studied form of spinal plasticity is spinal memory for noxious (nociceptive) stimulation. Numerous papers have described central pain as a spinally-stored memory that enhances future responses to ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Ferguson AR,Huie JR,Crown ED,Grau JW

    更新日期:2012-10-04 00:00:00

  • Haploinsufficiency of Dspp Gene Causes Dentin Dysplasia Type II in Mice.

    abstract::Dentin dysplasia (DD) and dentinogenesis imperfecta (DGI) patients have abnormal structure, morphology, and function of dentin. DD-II, DGI-II, and DGI-III are caused by heterozygous mutations in the dentin sialophosphoprotein (DSPP) gene in humans. Evidences have shown that loss of function of DSPP in Dspp knockout mi...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Shi C,Ma N,Zhang W,Ye J,Shi H,Xiang D,Wu C,Song L,Zhang N,Liu Q

    更新日期:2020-11-09 00:00:00

  • Intestinal Epithelial Cells Respond to Chronic Inflammation and Dysbiosis by Synthesizing H2O2.

    abstract::The microbes in the gastrointestinal tract are separated from the host by a single layer of intestinal epithelial cells (IECs) that plays pivotal roles in maintaining homeostasis by absorbing nutrients and providing a physical and immunological barrier to potential pathogens. Preservation of homeostasis requires the c...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Burgueño JF,Fritsch J,Santander AM,Brito N,Fernández I,Pignac-Kobinger J,Conner GE,Abreu MT

    更新日期:2019-12-12 00:00:00

  • High-Intensity Interval Training in Normobaric Hypoxia Leads to Greater Body Fat Loss in Overweight/Obese Women than High-Intensity Interval Training in Normoxia.

    abstract::A moderate hypoxic stimulus is considered a promising therapeutic modality for several pathological states including obesity. There is scientific evidence suggesting that when hypoxia and physical activity are combined, they could provide benefits for the obese population. The aim of the present study was to investiga...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Camacho-Cardenosa A,Camacho-Cardenosa M,Burtscher M,Martínez-Guardado I,Timon R,Brazo-Sayavera J,Olcina G

    更新日期:2018-02-07 00:00:00

  • Effects of Topical Icing on Inflammation, Angiogenesis, Revascularization, and Myofiber Regeneration in Skeletal Muscle Following Contusion Injury.

    abstract::Contusion injuries in skeletal muscle commonly occur in contact sport and vehicular and industrial workplace accidents. Icing has traditionally been used to treat such injuries under the premise that it alleviates pain, reduces tissue metabolism, and modifies vascular responses to decrease swelling. Previous research ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Singh DP,Barani Lonbani Z,Woodruff MA,Parker TJ,Steck R,Peake JM

    更新日期:2017-03-07 00:00:00

  • F1F0-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation.

    abstract::F1F0-ATP synthase inhibitory factor 1 (IF1) inhibits the reverse mode of F1F0-ATP synthase, and therefore protects cellular ATP content at the expense of accelerated loss of mitochondrial membrane potential (ΔΨm). There is considerable variability in IF1 expression and its influence on bioenergetics between different ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Tanton H,Voronina S,Evans A,Armstrong J,Sutton R,Criddle DN,Haynes L,Schmid MC,Campbell F,Costello E,Tepikin AV

    更新日期:2018-07-11 00:00:00

  • Nanotherapeutics for Treatment of Pulmonary Arterial Hypertension.

    abstract::Pulmonary arterial hypertension (PAH) is a devastating and fatal chronic lung disease. While current pharmacotherapies have improved patient quality of life, PAH drugs suffer from limitations in the form of short-term pharmacokinetics, instability, and poor organ specificity. Traditionally, nanotechnology-based delive...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审


    authors: Segura-Ibarra V,Wu S,Hassan N,Moran-Guerrero JA,Ferrari M,Guha A,Karmouty-Quintana H,Blanco E

    更新日期:2018-07-13 00:00:00

  • Post-mortem Characterisation of a Case With an ACTG1 Variant, Agenesis of the Corpus Callosum and Neuronal Heterotopia.

    abstract::Cytoplasmic Actin Gamma 1 (ACTG1) gene variant are autosomal dominant and can cause CNS anomalies (Baraitser Winter Malformation Syndrome; BWMS). ACTG1 anomalies in offspring include agenesis of the corpus callosum (ACC) and neuronal heterotopia which are ectopic nodules of nerve cells that failed to migrate appropria...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Vontell R,Supramaniam VG,Davidson A,Thornton C,Marnerides A,Holder-Espinasse M,Lillis S,Yau S,Jansson M,Hagberg HE,Rutherford MA

    更新日期:2019-05-24 00:00:00

  • Association between Carotid Intima Media Thickness and Heart Rate Variability in Adults at Increased Cardiovascular Risk.

    abstract::Background: Atherosclerotic carotid intima-media thickness (IMT) may be associated with alterations in the sensitivity of carotid baroreceptors. The aim of this study was to investigate the association between carotid IMT and the autonomic modulation of heart rate variability (HRV). Methods: A total of 101 subjects we...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Pereira VL Jr,Dobre M,Dos Santos SG,Fuzatti JS,Oliveira CR,Campos LA,Brateanu A,Baltatu OC

    更新日期:2017-04-26 00:00:00

  • Regulators of Collagen Fibrillogenesis during Molar Development in the Mouse.

    abstract::Development of mammalian teeth and surrounding tissues includes time-space changes in the extracellular matrix composition and organization. This requires complex control mechanisms to regulate its synthesis and remodeling. Fibril-associated collagens with interrupted triple helices (FACITs) and a group of small leuci...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Zvackova I,Matalova E,Lesot H

    更新日期:2017-08-02 00:00:00

  • R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/β-Catenin Signaling.

    abstract::Odontoblast cells generated from human dental pulp stem/progenitor cells (hDPSCs) secrete reparative dentin in responds to an injury. Endogenous Wnt signaling is also activated during this process, and these Wnt-activated cells are responsible for the following repair response. R-spondin 2 (Rspo2) is a potent stem cel...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Gong Y,Yuan S,Sun J,Wang Y,Liu S,Guo R,Dong W,Li R

    更新日期:2020-08-07 00:00:00

  • In vivo Sarcomere Lengths and Sarcomere Elongations Are Not Uniform across an Intact Muscle.

    abstract::Sarcomere lengths have been a crucial outcome measure for understanding and explaining basic muscle properties and muscle function. Sarcomere lengths for a given muscle are typically measured at a single spot, often in the mid-belly of the muscle, and at a given muscle length. It is then assumed implicitly that the sa...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Moo EK,Fortuna R,Sibole SC,Abusara Z,Herzog W

    更新日期:2016-05-25 00:00:00

  • Contribution of Extracellular Vesicles in Rebuilding Injured Muscles.

    abstract::Skeletal myofibers are injured due to mechanical stresses experienced during physical activity, or due to myofiber fragility caused by genetic diseases. The injured myofiber needs to be repaired or regenerated to restore the loss in muscle tissue function. Myofiber repair and regeneration requires coordinated action o...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审


    authors: Bittel DC,Jaiswal JK

    更新日期:2019-07-18 00:00:00

  • In vivo Neural Crest Cell Migration Is Controlled by "Mixotaxis".

    abstract::Directed cell migration is essential all along an individual's life, from embryogenesis to tissue repair and cancer metastasis. Thus, due to its biomedical relevance, directed cell migration is currently under intense research. Directed cell migration has been shown to be driven by an assortment of external biasing cu...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审


    authors: Barriga EH,Theveneau E

    更新日期:2020-11-25 00:00:00

  • Modeling Pulmonary Gas Exchange and Single-Exhalation Profiles of Carbon Monoxide.

    abstract::Exhaled breath carbon monoxide (eCO) is a candidate biomarker for non-invasive assessment of oxidative stress and respiratory diseases. Standard end-tidal CO analysis, however, cannot distinguish, whether eCO reflects endogenous CO production, lung diffusion properties or exogenous sources, and is unable to resolve a ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Ghorbani R,Blomberg A,Schmidt FM

    更新日期:2018-07-30 00:00:00

  • The impact of escitalopram on vagally mediated cardiovascular function to stress and the moderating effects of vigorous physical activity: a randomized controlled treatment study in healthy participants.

    abstract::Recent concerns over the impact of antidepressant medications, including the selective serotonin reuptake inhibitors (SSRIs), on cardiovascular function highlight the importance of research on the moderating effects of specific lifestyle factors such as physical activity. Studies in affective neuroscience have demonst...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章


    authors: Hanson CS,Outhred T,Brunoni AR,Malhi GS,Kemp AH

    更新日期:2013-09-24 00:00:00

  • Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders.

    abstract::The goal here is to describe our current understanding of heme metabolism and the deleterious effects of "free" heme on immunological processes, endothelial function, systemic inflammation, and various end-organ tissues (e.g., kidney, lung, liver, etc.), with particular attention paid to the role of hemopexin (HPX). B...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审


    authors: Smith A,McCulloh RJ

    更新日期:2015-06-30 00:00:00