Receptor Characterization and Functional Activity of Pyrokinins on the Hindgut in the Adult Mosquito, Aedes aegypti.

abstract：:Insecticidal effects of Bacillus thuringiensis Cry toxins in hemocoel of larvae have not been properly evaluated. In the present study, hemocoelic injection of four representative Cry toxins i.e., Cry1Aa, Cry1Ab, Cry1Ac, and DOR5 to an economically important lepidopteran insect pest Achaea janata, induced larval morta...

journal_title：Frontiers in physiology

authors： Ningshen TJ,Chauhan VK,Dhania NK,Dutta-Gupta A

更新日期：2017-05-10 00:00:00

abstract：:The mouse is one of the most important model organisms for understanding human genetic function and disease. This includes characterization of the factors that influence energy expenditure and dysregulation of energy balance leading to obesity and its sequelae. Measuring energy metabolism in the mouse presents a chall...

journal_title：Frontiers in physiology

authors： Speakman JR

更新日期：2013-03-14 00:00:00

abstract：:In cardiac tissues, the expression of multiple connexins (Cx40, Cx43, Cx45, and Cx30.2) is a requirement for proper development and function. Gap junctions formed by these connexins have distinct permeability and gating mechanisms. Since a single cell can express more than one connexin isoform, the formation of hetero...

journal_title：Frontiers in physiology

authors： Zhong G,Akoum N,Appadurai DA,Hayrapetyan V,Ahmed O,Martinez AD,Beyer EC,Moreno AP

更新日期：2017-05-29 00:00:00

abstract：:Studies have revealed a robust and independent correlation between chronic kidney disease (CKD) and cardiovascular (CV) events, including death, heart failure, and myocardial infarction. Recent clinical trials extend this range of adverse CV events, including malignant ventricular arrhythmias and sudden cardiac death ...

journal_title：Frontiers in physiology

authors： Kiuchi MG,Ho JK,Nolde JM,Gavidia LML,Carnagarin R,Matthews VB,Schlaich MP

更新日期：2020-01-14 00:00:00

abstract：Background:Walking patterns can provide important indications of a person's health status and be beneficial in the early diagnosis of individuals with a potential walking disorder. For appropriate gait analysis, it is critical that natural functional walking characteristics are captured, rather than those experienced i...

journal_title：Frontiers in physiology

authors： Renggli D,Graf C,Tachatos N,Singh N,Meboldt M,Taylor WR,Stieglitz L,Schmid Daners M

更新日期：2020-02-20 00:00:00

abstract：:Comparison of genomic sequences from diverse vertebrate species has revealed numerous highly conserved regions that do not appear to encode proteins or functional RNAs. Often these "conserved non-coding elements," or CNEs, can direct gene expression to specific tissues in transgenic models, demonstrating they have reg...

journal_title：Frontiers in physiology

authors： Turner EE,Cox TC

更新日期：2014-01-21 00:00:00

abstract：:Although a causal link between chronic inflammation and cancer has been established, the exact molecular mechanism linking inflammation to cancer remains largely unknown. It was previously postulated that molecular switches responsible for cancer cell development, and for infiltration of inflammatory cells into cancer...

journal_title：Frontiers in physiology

authors： Liu ST,Pham H,Pandol SJ,Ptasznik A

更新日期：2014-01-16 00:00:00

abstract：:Lactic acid and short chain fatty acids (SCFAs) produced by vaginal microbiota have reported antimicrobial and immune modulatory activities indicating their potential as biomarkers of disease and/or disease susceptibility. In asymptomatic women of reproductive-age the vaginal microbiota is comprised of lactic acid-pro...

journal_title：Frontiers in physiology

authors： Aldunate M,Srbinovski D,Hearps AC,Latham CF,Ramsland PA,Gugasyan R,Cone RA,Tachedjian G

更新日期：2015-06-02 00:00:00

abstract：:Red blood cell nitric oxide synthase (RBC-NOS) dependent NO production positively affects RBC deformability which is known to improve oxygen supply to the working tissue. Whole-body electrostimulation (WB-EMS) has been shown to improve maximum strength, sprinting and jumping performance, and to increase deformability ...

journal_title：Frontiers in physiology

authors： Filipovic A,Bizjak D,Tomschi F,Bloch W,Grau M

更新日期：2019-05-09 00:00:00

abstract：:Background: The short-term benefits of aerobic and resistance exercise in subjects affected by Peripheral Arterial Disease (PAD) are scarcely examined in interaction. This study aimed to identify the effects of combined aerobic and resistance exercise programs on walking performance compared with isolated aerobic exer...

journal_title：Frontiers in physiology

authors： Machado I,Sousa N,Paredes H,Ferreira J,Abrantes C

更新日期：2020-01-08 00:00:00

abstract：:Familial hypertrophic cardiomyopathy (HCM), due to point mutations in genes for sarcomere proteins such as myosin, occurs in 1/500 people and is the most common cause of sudden death in young individuals. Similar mutations in skeletal muscle, e.g., in the MYH7 gene for slow myosin found in both the cardiac ventricle a...

journal_title：Frontiers in physiology

authors： Månsson A

更新日期：2014-09-15 00:00:00

abstract：:Crayfish are capable of two rapid, escape reflexes that are mediated by two pairs of giant interneurons, the lateral giants (LG) and the medial giants (MG), which respond to threats presented to the abdomen or head and thorax, respectively. The LG has been the focus of study for many decades and the role of GABAergic ...

journal_title：Frontiers in physiology

authors： Swierzbinski ME,Herberholz J

更新日期：2018-04-27 00:00:00

abstract：:Aim: The hemodynamic response to mouse systemic anaphylaxis is characterized by an initial hypertension followed by sustained hypotension. However, the defense mechanisms of the sympathetic nervous system against this circulatory disturbance is not known. Here, we investigated the renal sympathetic nerve activity (RSN...

journal_title：Frontiers in physiology

authors： Zhang T,Tanida M,Uchida K,Suzuki Y,Yang W,Kuda Y,Kurata Y,Tominaga M,Shibamoto T

更新日期：2017-09-07 00:00:00

abstract：Background:More than 30-40% of uric acid is excreted via the intestine, and the dysfunction of intestinal epithelium disrupts uric acid excretion. The involvement of gut microbiota in hyperuricemia has been reported in previous studies, but the changes and mechanisms of intestinal immunity in hyperuricemia are still un...

journal_title：Frontiers in physiology

authors： Lv Q,Xu D,Zhang X,Yang X,Zhao P,Cui X,Liu X,Yang W,Yang G,Xing S

更新日期：2020-11-27 00:00:00

abstract：:Social attachment formed by filial imprinting in newborn chicks undergoes a process of memory consolidation that involves rearrangement of its neural storage substrates. In the first 3 h after imprinting it depends on the integrity of the intermediate medial mesopallium (IMM) and beyond that time on unidentified memor...

journal_title：Frontiers in physiology

authors： Tiunova AA,Komissarova NV,Anokhin KV

更新日期：2019-03-29 00:00:00

abstract：:Collective behavior in the forest tent caterpillar (Malacosoma disstria) meets the thermal constraints of being an early spring folivore, but introduces other constraints in food choice. These are minimized by state-dependent, inter-individual, and ontogenetic variations in responses to social cues. Forest tent caterp...

journal_title：Frontiers in physiology

authors： Despland E

更新日期：2013-03-22 00:00:00

abstract：:Background: Acute mountain sickness (AMS) is a common disabling condition in individuals experiencing high altitudes, which may progress to life-threatening high altitude cerebral edema. Today, no established biomarkers are available for prediction the susceptibility of AMS. MicroRNAs emerge as promising sensitive and...

journal_title：Frontiers in physiology

authors： Liu B,Huang H,Wu G,Xu G,Sun BD,Zhang EL,Chen J,Gao YQ

更新日期：2017-02-08 00:00:00

abstract：:The purpose of this systematic review was to investigate the scientific evidence to support the use of direct renin inhibitors (DRIs) in diabetic nephropathy (DN). MEDLINE was searched for articles reported until 2018. A standardized dataset was extracted from articles describing the effects of DRIs on plasma renin ac...

journal_title：Frontiers in physiology

authors： Massolini BD,Contieri SSG,Lazarini GS,Bellacosa PA,Dobre M,Petroianu G,Brateanu A,Campos LA,Baltatu OC

更新日期：2020-03-12 00:00:00

abstract：:For early prevention of cardiovascular disease, early detection and risk factor insights are necessary. The autonomic balance reflects cardiovascular risk and can be measured by heart rate variability (HRV). Therefore, our purpose is to examine associations between HRV and the energy-related biomarkers leptin and adip...

journal_title：Frontiers in physiology

authors： Van De Wielle R,Michels N

更新日期：2017-07-12 00:00:00

abstract：:The recognition of invading pathogens and endogenous molecules from damaged tissues by toll-like receptors (TLRs) triggers protective self-defense mechanisms. However, excessive TLR activation disrupts the immune homeostasis by sustained pro-inflammatory cytokines and chemokines production and consequently contributes...

journal_title：Frontiers in physiology

authors： Gao W,Xiong Y,Li Q,Yang H

更新日期：2017-07-19 00:00:00

abstract：:Progressive aging induces several structural and functional alterations in the cardiovascular system, among whom particularly important are a reduced number of myocardial cells and increased interstitial collagen fibers, which result in impaired left ventricular diastolic function. Even in the absence of cardiovascula...

journal_title：Frontiers in physiology

authors： Vigorito C,Giallauria F

更新日期：2014-02-20 00:00:00

abstract：:Currently, neuropathic pain is an underestimated socioeconomic health problem affecting millions of people worldwide, which incidence may increase in the next years due to chronification of several diseases, such as cancer and diabetes. Growing evidence links neuropathic pain present in several disorders [i.e., spinal...

journal_title：Frontiers in physiology

authors： Carrasco C,Naziroǧlu M,Rodríguez AB,Pariente JA

更新日期：2018-02-14 00:00:00

abstract：:Coronary microembolization (CME) is an important clinical problem, and it is related to poor outcome. The specific molecular mechanisms of CME are not fully understood. In the present study, we established a mice model of CME. Isobaric tags for relative and absolute quantitation (iTRAQ) and liquid chromatography coupl...

journal_title：Frontiers in physiology

authors： Chen A,Chen Z,Xia Y,Lu D,Jia J,Hu K,Sun A,Zou Y,Qian J,Ge J

更新日期：2018-09-19 00:00:00

abstract：:Ocean acidification (OA) and warming seas are significant concerns for coastal systems and species. The Atlantic longfin squid, Doryteuthis pealeii, a core component of the Northwest Atlantic trophic web, has demonstrated impacts, such as reduced growth and delayed development, under high chronic exposure to acidifica...

journal_title：Frontiers in physiology

authors： Zakroff CJ,Mooney TA

更新日期：2020-05-20 00:00:00

abstract：:Knee injury increases the risk of developing knee osteoarthritis (OA). Recent evidence suggests involvement of oxidative stress induced by inflammation and bleeding in the joint. This study investigates the role in this process of α1-microglobulin (A1M), a plasma and tissue antioxidant protein with reducing function, ...

journal_title：Frontiers in physiology

authors： Larsson S,Åkerström B,Gram M,Lohmander LS,Struglics A

更新日期：2018-11-16 00:00:00

abstract：:Head-down bed rest (HDBR) is commonly considered as ground-based analog to spaceflight and simulates the headward fluid shift and cardiovascular deconditioning associated with spaceflight. We investigated in healthy volunteers whether HDBR, with or without countermeasures, affect cerebral autoregulation (CA). Twelve m...

journal_title：Frontiers in physiology

authors： Kermorgant M,Nasr N,Custaud MA,Navasiolava N,Arbeille P,Guinet P,Labrunée M,Besnier F,Arvanitis DN,Czosnyka M,Senard JM,Pavy-Le Traon A

更新日期：2019-08-27 00:00:00

abstract：:Inflammation-induced impaired function of vascular endothelium may cause leakage of plasma proteins that can lead to edema. Proteins may leave the vascular lumen through two main paracellular and transcellular pathways. As the first involves endothelial cell (EC) junction proteins and the second caveolae formation, th...

journal_title：Frontiers in physiology

authors： Muradashvili N,Tyagi R,Lominadze D

更新日期：2012-05-31 00:00:00

abstract：:Sarcopenia is the age-related progressive loss of skeletal muscle mass and strength finally leading to poor physical performance. Impaired myogenesis contributes to the pathogenesis of sarcopenia, while mitochondrial dysfunctions are thought to play a primary role in skeletal muscle loss during aging. Here we studied ...

journal_title：Frontiers in physiology

authors： Belli R,Bonato A,De Angelis L,Mirabilii S,Ricciardi MR,Tafuri A,Molfino A,Leigheb M,Costelli P,Caruso M,Muscaritoli M,Ferraro E

更新日期：2019-07-10 00:00:00

abstract：:Singlet oxygen generated in a type II photodynamic action, due to its limited lifetime (1 μs) and reactive distance (<10 nm), could regulate live cell function nanoscopically. The genetically-encoded protein photosensitizers (engineered fluorescent proteins such as KillerRed, TagRFP, and flavin-binding proteins such a...

journal_title：Frontiers in physiology

authors： Jiang HN,Li Y,Cui ZJ

更新日期：2017-04-04 00:00:00

abstract：:During formation of the secondary palate in mammalian embryos, two vertically oriented palatal shelves rapidly elevate into a horizontal position above the tongue, meet at the midline, and fuse to form a single entity. Previous observations suggested that elevation occurs by a simple 90° rotation of the palatal shelve...

journal_title：Frontiers in physiology

authors： Chiquet M,Blumer S,Angelini M,Mitsiadis TA,Katsaros C

更新日期：2016-09-07 00:00:00