Photodynamic Physiology-Photonanomanipulations in Cellular Physiology with Protein Photosensitizers.

abstract：:Left ventricular (LV) myocardial dysfunction occurs after myocardial infarction (MI) is associated with the location, infarct size, and transmurality degrees of MI. The myocardial strain is a sensitive index used for the quantification of myocardium dysfunction. This study used Tissue-Tracking to evaluate whether the ...

journal_title：Frontiers in physiology

authors： Li S,Zhao L,Lu A,Tian J,Gong L,Ma X

更新日期：2020-12-10 00:00:00

abstract：:Lactic acid and short chain fatty acids (SCFAs) produced by vaginal microbiota have reported antimicrobial and immune modulatory activities indicating their potential as biomarkers of disease and/or disease susceptibility. In asymptomatic women of reproductive-age the vaginal microbiota is comprised of lactic acid-pro...

journal_title：Frontiers in physiology

authors： Aldunate M,Srbinovski D,Hearps AC,Latham CF,Ramsland PA,Gugasyan R,Cone RA,Tachedjian G

更新日期：2015-06-02 00:00:00

abstract：AIM:The aim of the present study was to analyze the response of vascular circulating microRNAs (miRNAs; miR-16, miR-21, miR-126) and the VEGF mRNA following an acute bout of HIIT and HVT in children. METHODS:Twelve healthy competitive young male cyclists (14.4 ± 0.8 years; 57.9 ± 9.4 ml·min(-1)·kg(-1) peak oxygen upta...

journal_title：Frontiers in physiology

authors： Kilian Y,Wehmeier UF,Wahl P,Mester J,Hilberg T,Sperlich B

更新日期：2016-03-14 00:00:00

abstract：:This study investigates human performance in a cyclic Fitts task at three different scales of observation, either in the presence (difficult condition) or in the absence (easy condition) of a speed-accuracy trade-off. At the fastest scale, the harmonicity of the back and forth movements, which reflects the dissipation...

journal_title：Frontiers in physiology

authors： Wijnants ML,Cox RF,Hasselman F,Bosman AM,Van Orden G

更新日期：2012-05-23 00:00:00

abstract：:Current scientific debates center on the impact of lipids and mitochondrial function on diverse aspects of human health, nutrition and disease, among them the association of lipotoxicity with the onset of insulin resistance in skeletal muscle, and with heart dysfunction in obesity and diabetes. Mitochondria play a fun...

journal_title：Frontiers in physiology

authors： Aon MA,Bhatt N,Cortassa SC

更新日期：2014-07-31 00:00:00

abstract：:Skeletal muscles are the largest cells in the body and are one of the few syncytial ones. There is a longstanding belief that a given nucleus controls a defined volume of cytoplasm, so when a muscle grows (hypertrophy) or shrinks (atrophy), the number of myonuclei change accordingly. This phenomenon is known as the "m...

journal_title：Frontiers in physiology

authors： Schwartz LM

更新日期：2019-01-25 00:00:00

abstract：:Skeletal muscle mass reflects a dynamic turnover between net protein synthesis and degradation. In addition, satellite cell inclusion may contribute to increase muscle mass while fiber loss results in a reduction of muscle mass. Since 2010, a few studies looked at the involvement of the newly discovered Hippo pathway ...

journal_title：Frontiers in physiology

authors： Gnimassou O,Francaux M,Deldicque L

更新日期：2017-03-29 00:00:00

abstract：:The non-selective mechanosensitive ion channel PIEZO1 controls erythrocyte volume homeostasis. Different missense gain-of-function mutations in PIEZO1 gene have been identified that cause Hereditary Xerocytosis (HX), a rare autosomal dominant haemolytic anemia. PIEZO1 expression is not limited to erythrocytes and expr...

journal_title：Frontiers in physiology

authors： Aglialoro F,Hofsink N,Hofman M,Brandhorst N,van den Akker E

更新日期：2020-07-31 00:00:00

abstract：:Since the mid-1980s magnetic resonance imaging (MRI) has been investigated as a non- or minimally invasive tool to probe kidney allograft function. Despite this long-standing interest, MRI still plays a subordinate role in daily practice of transplantation nephrology. With the introduction of new functional MRI techni...

journal_title：Frontiers in physiology

authors： van Eijs MJM,van Zuilen AD,de Boer A,Froeling M,Nguyen TQ,Joles JA,Leiner T,Verhaar MC

更新日期：2017-05-16 00:00:00

abstract：BACKGROUND:The potential for cross acclimation between environmental stressors is not well understood. Thus, the aim of this investigation was to determine the effect of fixed-workload heat or hypoxic acclimation on cellular, physiological, and performance responses during post acclimation hypoxic exercise in humans. ...

journal_title：Frontiers in physiology

authors： Lee BJ,Miller A,James RS,Thake CD

更新日期：2016-03-08 00:00:00

abstract：:Excessive alcohol consumption is associated with hepatic steatosis and dysregulation of the gut microbiota in patients with alcohol use disorder (AUD). However, how gut microbiota responds when patients stop drinking has not been well studied. In this study, we use shotgun metagenomic sequencing to elucidate the alter...

journal_title：Frontiers in physiology

authors： Gao B,Emami A,Zhou R,Lang S,Duan Y,Wang Y,Jiang L,Loomba R,Brenner DA,Stärkel P,Schnabl B

更新日期：2020-04-24 00:00:00

abstract：:Purpose: To examine the effects of deceptively aggressive bike pacing on performance, pacing, and associated physiological and perceptual responses during simulated sprint-distance triathlon. Methods: Ten non-elite, competitive male triathletes completed three simulated sprint-distance triathlons (0.75 km swim, 500 kJ...

journal_title：Frontiers in physiology

authors： Taylor D,Smith MF

更新日期：2017-01-24 00:00:00

abstract：UNLABELLED:Limitations of current methods: Normalization of resting energy expenditure (REE) for body composition using the 2-compartment model fat mass (FM), and fat-free mass (FFM) has inherent limitations for the interpretation of REE and may lead to erroneous conclusions when comparing people with a wide range of a...

journal_title：Frontiers in physiology

authors： Bosy-Westphal A,Braun W,Schautz B,Müller MJ

更新日期：2013-03-25 00:00:00

abstract：:The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to the challenging field of virtual design and testing of technologies in a patient-specific environment. Given the recent advances in medical imaging, computational power and mathematical algorithms, patient-specific cardiac models ...

journal_title：Frontiers in physiology

authors： Zhong L,Zhang JM,Su B,Tan RS,Allen JC,Kassab GS

更新日期：2018-06-26 00:00:00

abstract：:Regular exercise prevents lipid abnormalities and conditions such as diabetes mellitus, hypertension, and obesity; it considerably benefits sedentary individuals. However, individuals exhibit highly variable responses to exercise, probably due to genetic variations. Animal models are typically used to investigate the ...

journal_title：Frontiers in physiology

authors： Tung YT,Hsu YJ,Liao CC,Ho ST,Huang CC,Huang WC

更新日期：2019-09-18 00:00:00

abstract：:Hyperbilirubinemia (HB) occurs in 90% of preterm newborns. Moderate HB can induce acute neurological disorders while severe HB has been linked to a higher incidence of apneas of prematurity. The present study aimed to test the hypothesis that even moderate HB disrupts cardiorespiratory control in preterm lambs. Two gr...

journal_title：Frontiers in physiology

authors： Specq ML,Bourgoin-Heck M,Samson N,Corbin F,Gestreau C,Richer M,Kadhim H,Praud JP

更新日期：2016-09-30 00:00:00

abstract：:Background: Previous studies have observed significant heterogeneity in the magnitude of change in measures of metabolic response to exercise training. There are a lack of studies examining the prevalence of non-responders (NRs) in children while considering other potential environmental factors involved such as biolo...

journal_title：Frontiers in physiology

authors： Alvarez C,Ramírez-Campillo R,Ramírez-Vélez R,Izquierdo M

更新日期：2017-06-29 00:00:00

abstract：:Ontologies and standards are very important parts of today's bioscience research. With the rapid increase of biological knowledge, they provide mechanisms to better store and represent data in a controlled and structured way, so that scientists can share the data, and utilize a wide variety of software and tools to ma...

journal_title：Frontiers in physiology

authors： Mi H,Thomas PD

更新日期：2011-02-21 00:00:00

abstract：Background:The aim of presented cross-sectional study was to determine the association of different types of physical activity (PA) with metabolic control in people with type 1 diabetes. Materials and Methods:A total of 109 adult subjects with type 1 diabetes were asked to complete the non-exercise activity thermogene...

journal_title：Frontiers in physiology

authors： Štotl I,Kambič T,Hadžić V,Zdolšek A

更新日期：2019-09-24 00:00:00

abstract：:While isolation of the pulmonary veins is firmly established as effective treatment for the majority of paroxysmal atrial fibrillation (AF) patients, there is recognition that patients with persistent AF have substrate for perpetuation of arrhythmia existing outside of the pulmonary veins. Various computational approa...

journal_title：Frontiers in physiology

authors： Stiles MK,Sanders P,Lau DH

更新日期：2018-09-18 00:00:00

abstract：:We previously demonstrated that ureteral obstruction is associated with a urinary concentrating defect and reduced expression of renal aquaporins (AQPs), in which the renin-angiotensin system (RAS) may play an important role. The aims of the present study were to examine whether the renin inhibitor aliskiren could pre...

journal_title：Frontiers in physiology

authors： Hu S,Xie H,Luo R,Feng P,Liu Q,Han M,Kong Y,Zou X,Wang W,Li C

更新日期：2019-09-13 00:00:00

abstract：:We investigate analytically the production of entropy during a breathing cycle in healthy and diseased lungs. First, we calculate entropy production in healthy lungs by applying the laws of thermodynamics to the well-known transpulmonary pressure-volume (P-V) curves of the lung under the assumption that lung tissue be...

journal_title：Frontiers in physiology

authors： Oliveira CL,Araújo AD,Bates JH,Andrade JS Jr,Suki B

更新日期：2016-03-01 00:00:00

abstract：:The olfactory system serves a vital role in the evolution and survival of insects, being involved in behaviors such as host seeking, foraging, mating, and oviposition. Odorant-binding proteins (OBPs) and chemosensory proteins (CSPs) are involved in the olfactory recognition process. In this study, BtabCSP11, a CSP11 g...

journal_title：Frontiers in physiology

authors： Zeng Y,Merchant A,Wu Q,Wang S,Kong L,Zhou X,Xie W,Zhang Y

更新日期：2020-06-30 00:00:00

abstract：:The microbial community of the gut conveys significant benefits to host physiology. A clear relationship has now been established between gut bacteria and host metabolism in which microbial-mediated gut hormone release plays an important role. Within the gut lumen, bacteria produce a number of metabolites and contain ...

journal_title：Frontiers in physiology

authors： Martin AM,Sun EW,Rogers GB,Keating DJ

更新日期：2019-04-16 00:00:00

abstract：:Respiratory/inspiratory muscle training (RMT/IMT) has been proposed to improve the endurance performance of athletes in normoxia. In recent years, due to the increased use of hypoxic training method among athletes, the RMT applicability has also been tested as a method to minimize adverse effects since hyperventilatio...

journal_title：Frontiers in physiology

authors： Álvarez-Herms J,Julià-Sánchez S,Corbi F,Odriozola-Martínez A,Burtscher M

更新日期：2019-01-15 00:00:00

abstract：:One of the key defining features of an endogenous circadian clock is that it can be entrained or set to local time. Though a number of cues can perform this role, light is the predominant environmental signal that acts to entrain circadian pacemakers in most species. For the past 20 years, a great deal of work has bee...

journal_title：Frontiers in physiology

authors： Steindal IAF,Whitmore D

更新日期：2020-08-14 00:00:00

abstract：:Na(+)/Ca(2+) exchanger (NCX) proteins extrude Ca(2+) from the cell to maintain cellular homeostasis. Since NCX proteins contribute to numerous physiological and pathophysiological events, their pharmacological targeting has been desired for a long time. This intervention remains challenging owing to our poor understan...

journal_title：Frontiers in physiology

authors： Giladi M,Tal I,Khananshvili D

更新日期：2016-02-09 00:00:00

abstract：:Resistance training with blood flow restriction is typically performed during single exercises for the lower- or upper-body, which may not replicate real world programming. The present study examined the change in muscle strength and mass in a young healthy population during an 8-week whole body resistance training pr...

journal_title：Frontiers in physiology

authors： Brandner CR,Clarkson MJ,Kidgell DJ,Warmington SA

更新日期：2019-09-10 00:00:00

abstract：:Data indicate endothelium-dependent dilation (EDD) may be preserved in the skeletal muscle microcirculation of young, obese adults. Preserved EDD might be mediated by compensatory mechanisms, impeding insight into preclinical vascular dysfunction. We aimed to determine the functional roles of nitric oxide synthase (NO...

journal_title：Frontiers in physiology

authors： Harrell JW,Johansson RE,Evans TD,Sebranek JJ,Walker BJ,Eldridge MW,Serlin RC,Schrage WG

更新日期：2015-12-22 00:00:00

abstract：:This work investigates the effect of arterial bifurcation angulation on atherosclerosis development through in-silico simulations of coupled cell dynamics. The computational model presented here combines cellular pathways, fluid dynamics, and physiologically-realistic vessel geometries as observed in the human vascula...

journal_title：Frontiers in physiology

authors： Dowding S,Zakkaroff C,Moore S,David T

更新日期：2018-10-31 00:00:00