Zebrafish Circadian Clock Entrainment and the Importance of Broad Spectral Light Sensitivity.

abstract：:Sudden cardiac death caused by ventricular arrhythmias is among the leading causes of mortality, with approximately half of all deaths attributed to heart disease worldwide. Periodic repolarization dynamics (PRD) is a novel marker of repolarization instability and strong predictor of death in patients post-myocardial ...

journal_title：Frontiers in physiology

authors： Ang R,Marina N

更新日期：2020-03-18 00:00:00

abstract：:Adipokinetic hormones (AKHs) are well known to mobilize lipids and carbohydrates for energy-consuming activities in insects. These neuropeptides exert their functions by interacting with AKH receptors (AKHRs) located on the plasma membrane of fat body cells, which regulates energy mobilization by stimulating lipolysis...

journal_title：Frontiers in physiology

authors： Lu K,Wang Y,Chen X,Zhang X,Li W,Cheng Y,Li Y,Zhou J,You K,Song Y,Zhou Q,Zeng R

更新日期：2019-01-08 00:00:00

abstract：:Leucine-rich repeat containing protein 10 (LRRC10) is a cardiomyocyte-specific member of the Leucine-rich repeat containing (LRRC) protein superfamily with critical roles in cardiac function and disease pathogenesis. Recent studies have identified LRRC10 mutations in human idiopathic dilated cardiomyopathy (DCM) and L...

journal_title：Frontiers in physiology

authors： Brody MJ,Lee Y

更新日期：2016-08-03 00:00:00

abstract：:The multifunctional CD36 scavenger receptor facilitates fatty acid (FA) uptake and oxidation and it has been involved in the pathophysiology related to dysfunctional FA metabolism. The common variant in the CD36 gene, rs1761667 (A/G), whose allele A is characterized by a reduced protein expression, has been associated...

journal_title：Frontiers in physiology

authors： Melis M,Carta G,Pintus S,Pintus P,Piras CA,Murru E,Manca C,Di Marzo V,Banni S,Tomassini Barbarossa I

更新日期：2017-12-06 00:00:00

abstract：:Consumption of acidic foods and drinks and other factors that cause enamel wear are responsible for the daily enamel loss and degradation. Use of some toothpastes that have been showed to possess different properties of remineralisation and/or repair of the enamel surface may help to protect tooth enamel. The aim of t...

journal_title：Frontiers in physiology

authors： Lelli M,Putignano A,Marchetti M,Foltran I,Mangani F,Procaccini M,Roveri N,Orsini G

更新日期：2014-09-05 00:00:00

abstract：:New therapeutic agents are needed in digestive tract tumors. Co-029/tspan8 is a tetraspanin frequently expressed on human colorectal tumors, In this work, we report the effects of the monoclonal antibody Ts29.2, targeting Co-029/tspan8, on colorectal tumor cells in vitro and after implantation in nude mice. HT29, Isre...

journal_title：Frontiers in physiology

authors： Ailane N,Greco C,Zhu Y,Sala-Valdés M,Billard M,Casal I,Bawa O,Opolon P,Rubinstein E,Boucheix C

更新日期：2014-09-19 00:00:00

abstract：:This work investigates the effect of arterial bifurcation angulation on atherosclerosis development through in-silico simulations of coupled cell dynamics. The computational model presented here combines cellular pathways, fluid dynamics, and physiologically-realistic vessel geometries as observed in the human vascula...

journal_title：Frontiers in physiology

authors： Dowding S,Zakkaroff C,Moore S,David T

更新日期：2018-10-31 00:00:00

abstract：:Teeth and dentitions contain many morphological characters which give them a particularly important weight in comparative anatomy, systematics, physiology and ecology. As teeth are organs that contain the hardest mineralized tissues vertebrates can produce, their fossil remains are abundant and the study of their anat...

journal_title：Frontiers in physiology

authors： Bertin TJC,Thivichon-Prince B,LeBlanc ARH,Caldwell MW,Viriot L

更新日期：2018-11-21 00:00:00

abstract：:We aimed to investigate the effects of resistance training (RT) combined with no-load isometric actions (iso-holds) during the inter-set recovery period versus RT that involves passive inter-set rest on muscular strength, muscular hypertrophy, and muscular endurance in resistance-trained men. Twenty-seven resistance-t...

journal_title：Frontiers in physiology

authors： Schoenfeld BJ,Grgic J,Contreras B,Delcastillo K,Alto A,Haun C,De Souza EO,Vigotsky AD

更新日期：2020-01-15 00:00:00

abstract：:Adipose tissue is recognized as an important organ with metabolic, regulatory, and plastic roles. Adipose tissue-derived stem cells (ASCs) with self-renewal properties localize in the stromal vascular fraction (SVF) being present in a vascular niche, thereby, contributing to local regulation of angiogenesis and vessel...

journal_title：Frontiers in physiology

authors： Panina YA,Yakimov AS,Komleva YK,Morgun AV,Lopatina OL,Malinovskaya NA,Shuvaev AN,Salmin VV,Taranushenko TE,Salmina AB

更新日期：2018-11-26 00:00:00

abstract：:The aim of this study is to detect the effects of C60 fullerenes, which possess pronounced antioxidant properties, in comparison with the actions of the known exogenous antioxidants N-acetylcysteine (NAC) and β-Alanine in terms of exercise tolerance and contractile property changes of the m. triceps surae (TS) during ...

journal_title：Frontiers in physiology

authors： Vereshchaka IV,Bulgakova NV,Maznychenko AV,Gonchar OO,Prylutskyy YI,Ritter U,Moska W,Tomiak T,Nozdrenko DM,Mishchenko IV,Kostyukov AI

更新日期：2018-05-15 00:00:00

abstract：:As opposed to the standard tolerogenic apoptosis, immunogenic cell death (ICD) constitutes a type of cellular demise that elicits an adaptive immune response. ICD has been characterized in malignant cells following cytotoxic interventions, such as chemotherapy or radiotherapy. Briefly, ICD of cancer cells releases som...

journal_title：Frontiers in physiology

authors： Checcoli A,Pol JG,Naldi A,Noel V,Barillot E,Kroemer G,Thieffry D,Calzone L,Stoll G

更新日期：2020-11-12 00:00:00

abstract：:Directed cell migration is essential all along an individual's life, from embryogenesis to tissue repair and cancer metastasis. Thus, due to its biomedical relevance, directed cell migration is currently under intense research. Directed cell migration has been shown to be driven by an assortment of external biasing cu...

journal_title：Frontiers in physiology

authors： Barriga EH,Theveneau E

更新日期：2020-11-25 00:00:00

abstract：:Objective: This study aims to investigate the effect of astragaloside IV on adipose lipolysis and hepatic gluconeogenesis. Methods: High-fat diet (HFD) feeding induced adipose dysfunction with enhanced endogenous glucose production in mice. The effects of Astragaloside IV on lipolysis and hepatic glucose production we...

journal_title：Frontiers in physiology

authors： Du Q,Zhang S,Li A,Mohammad IS,Liu B,Li Y

更新日期：2018-01-23 00:00:00

abstract：:Skeletal muscle is a plastic tissue that undergoes cellular and metabolic adaptations under conditions of increased contractile activity such as exercise. Using adult zebrafish as an exercise model, we previously demonstrated that swimming training stimulates hypertrophy and vascularization of fast muscle fibers, cons...

journal_title：Frontiers in physiology

authors： Rovira M,Arrey G,Planas JV

更新日期：2017-12-18 00:00:00

abstract：:For many model organisms traditionally in use for cardiac electrophysiological studies, characterization of ion channel genes is lacking. We focused here on two genes encoding the inward rectifier current, KCNJ2 and KCNJ12, in the dog heart. A combination of RT-PCR, 5'-RACE, and 3'-RACE demonstrated the status of KCNJ...

journal_title：Frontiers in physiology

authors： Houtman MJ,Takanari H,Kok BG,van Eck M,Montagne DR,Vos MA,de Boer TP,van der Heyden MA

更新日期：2012-01-30 00:00:00

abstract：:Since the mid-1980s magnetic resonance imaging (MRI) has been investigated as a non- or minimally invasive tool to probe kidney allograft function. Despite this long-standing interest, MRI still plays a subordinate role in daily practice of transplantation nephrology. With the introduction of new functional MRI techni...

journal_title：Frontiers in physiology

authors： van Eijs MJM,van Zuilen AD,de Boer A,Froeling M,Nguyen TQ,Joles JA,Leiner T,Verhaar MC

更新日期：2017-05-16 00:00:00

abstract：:The aims of the present study were to (a) examine recovery time-course and (b) analyze the usefulness of the Hooper-Index (wellness index) and resting heart rate variability (HRV) in professional soccer players during an in-season phase. The Hooper-Index and resting HRV were collected on matchday and on the four follo...

journal_title：Frontiers in physiology

authors： Rabbani A,Clemente FM,Kargarfard M,Chamari K

更新日期：2019-02-19 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) play important roles in transcriptional and post-transcriptional regulation. However, little is currently known about the mechanisms by which they regulate skeletal muscle development in the chicken. In this study, we used RNA sequencing to profile the leg muscle transcriptome (lncRNA an...

journal_title：Frontiers in physiology

authors： Li Z,Ouyang H,Zheng M,Cai B,Han P,Abdalla BA,Nie Q,Zhang X

更新日期：2017-01-09 00:00:00

abstract：:Nedd4-2 is a ubiquitin ligase previously demonstrated to regulate endocytosis and lysosomal degradation of the epithelial Na(+) channel (ENaC) and other ion channels and transporters. Recent studies using Nedd4-2 knockout mice specifically in kidney or lung epithelia has revealed a critical role for this E3 ubiquitin ...

journal_title：Frontiers in physiology

authors： Rotin D,Staub O

更新日期：2012-06-21 00:00:00

abstract：:Temporal computations are important in the acoustic communication of anurans. In many cases, calls between closely related species are nearly identical spectrally but differ markedly in temporal structure. Depending on the species, calls can differ in pulse duration, shape and/or rate (i.e., amplitude modulation), dir...

journal_title：Frontiers in physiology

authors： Rose GJ

更新日期：2014-05-30 00:00:00

abstract：:Microvesicles (MVs) are released by most cell types in physiological conditions, but their number is often increased upon cellular activation or neoplastic transformation. This suggests that their detection may be helpful in pathological conditions to have information on activated cell types and, possibly, on the natu...

journal_title：Frontiers in physiology

authors： Colombo E,Borgiani B,Verderio C,Furlan R

更新日期：2012-03-29 00:00:00

abstract：:Red blood cell nitric oxide synthase (RBC-NOS) dependent NO production positively affects RBC deformability which is known to improve oxygen supply to the working tissue. Whole-body electrostimulation (WB-EMS) has been shown to improve maximum strength, sprinting and jumping performance, and to increase deformability ...

journal_title：Frontiers in physiology

authors： Filipovic A,Bizjak D,Tomschi F,Bloch W,Grau M

更新日期：2019-05-09 00:00:00

abstract：:Introduction: Endothelial progenitor cells (EPCs) display a unique ability to promote angiogenesis and restore endothelial function in injured blood vessels. NADPH oxidase 4 (NOX4)-derived hydrogen peroxide (H2O2) serves as a signaling molecule and promotes endothelial cell proliferation and migration as well as prote...

journal_title：Frontiers in physiology

authors： Hakami NY,Ranjan AK,Hardikar AA,Dusting GJ,Peshavariya HM

更新日期：2017-03-23 00:00:00

abstract：:To determine the level of hypoxia from which muscle activation (MA) is reduced during incremental exercise to exhaustion (IE), and the role played by PIO2 in this process, ten volunteers (21 ± 2 years) performed four IE in severe acute hypoxia (SAH) (PIO2 = 73 mmHg). Upon exhaustion, subjects were asked to continue ex...

journal_title：Frontiers in physiology

authors： Torres-Peralta R,Losa-Reyna J,Morales-Alamo D,González-Izal M,Pérez-Suárez I,Ponce-González JG,Izquierdo M,Calbet JA

更新日期：2016-08-17 00:00:00

abstract：:Red blood cell (RBC) deformability is an important determinant of the microcirculation. It is influenced by various hematological parameters but also by nitric oxide (NO) which is produced in RBC from L-arginine by RBC-NO synthase. Longitudinal studies on blood profile, deformability at rest and NO levels but also dif...

journal_title：Frontiers in physiology

authors： Grau M,Cremer JM,Schmeichel S,Kunkel M,Bloch W

更新日期：2018-12-19 00:00:00

abstract：UNLABELLED:Since Matrix metalloproteinases (MMPs) have been suggested to contribute to dentin caries progression, the hypothesis that MMP inhibition would affect the progression of dentin caries is clinically relevant. Grape seed extracts (GSE) have been previously reported to be natural inhibitors of MMPs. OBJECTIVE:...

journal_title：Frontiers in physiology

authors： Khaddam M,Salmon B,Le Denmat D,Tjaderhane L,Menashi S,Chaussain C,Rochefort GY,Boukpessi T

更新日期：2014-10-31 00:00:00

abstract：:Dental and periodontal tissue development is a complex process involving various cell-types. A finely orchestrated network of communications between these cells is implicated. During early development, communications between cells from the oral epithelium and the underlying mesenchyme govern the dental morphogenesis w...

journal_title：Frontiers in physiology

authors： Gama A,Navet B,Vargas JW,Castaneda B,Lézot F

更新日期：2015-11-05 00:00:00

abstract：:Realistic electrocardiogram (ECG) simulation with numerical models is important for research linking cellular and molecular physiology to clinically observable signals, and crucial for patient tailoring of numerical heart models. However, ECG simulation with a realistic torso model is computationally much harder than ...

journal_title：Frontiers in physiology

authors： Potse M

更新日期：2018-04-20 00:00:00

abstract：:As verbal encouragement (VE) is used in high intensity functional exercise testing, this randomized controlled crossover study aimed at investigating whether VE affects high intensity functional strength and endurance performance testing. We further examined between-day variability of high intensity functional strengt...

journal_title：Frontiers in physiology

authors： Engel FA,Faude O,Kölling S,Kellmann M,Donath L

更新日期：2019-04-25 00:00:00