Plasticity of Adipose Tissue-Derived Stem Cells and Regulation of Angiogenesis.

abstract：:Aging is associated with a decline in cardiac function due to a decreased myocardial reserve. This adverse cardiac remodeling comprises of a variety of changes, including a reduction in mitochondrial function and a decline in the expression of the peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a...

journal_title：Frontiers in physiology

authors： Whitehead N,Gill JF,Brink M,Handschin C

更新日期：2018-03-21 00:00:00

abstract：:A Boolean model is a simple, discrete and dynamic model without the need to consider the effects at the intermediate levels. However, little effort has been made into constructing activation, inhibition, and protein decay networks, which could indicate the direct roles of a gene (or its synthesized protein) as an acti...

journal_title：Frontiers in physiology

authors： Chen L,Kulasiri D,Samarasinghe S

更新日期：2018-09-25 00:00:00

abstract：:About 14% of veterans who suffer from Gulf war illness (GWI) complain of some form of gastrointestinal disorder but with no significant markers of clinical pathology. Our previous studies have shown that exposure to GW chemicals resulted in altered microbiome which was associated with damage associated molecular patte...

journal_title：Frontiers in physiology

authors： Kimono D,Sarkar S,Albadrani M,Seth R,Bose D,Mondal A,Li Y,Kar AN,Nagarkatti M,Nagarkatti P,Sullivan K,Janulewicz P,Lasley S,Horner R,Klimas N,Chatterjee S

更新日期：2019-10-14 00:00:00

abstract：:We explored the metagenomic, metabolomic and trace metal makeup of intestinal microbiota and environment in healthy male participants during the run-in (5 day) and the following three 21-day interventions: normoxic bedrest (NBR), hypoxic bedrest (HBR) and hypoxic ambulation (HAmb) which were carried out within a contr...

journal_title：Frontiers in physiology

authors： Šket R,Debevec T,Kublik S,Schloter M,Schoeller A,Murovec B,Vogel Mikuš K,Makuc D,Pečnik K,Plavec J,Mekjavić IB,Eiken O,Prevoršek Z,Stres B

更新日期：2018-03-13 00:00:00

abstract：Background:The aim of this study is to report on the genetic composition of Brugada syndrome (BrS) patients undergoing genetic testing in Hong Kong. Methods:Patients with suspected BrS who presented to the Hospital Authority of Hong Kong between 1997 and 2019, and underwent genetic testing, were analyzed retrospective...

journal_title：Frontiers in physiology

authors： Tse G,Lee S,Liu T,Yuen HC,Wong ICK,Mak C,Mok NS,Wong WT

更新日期：2020-09-18 00:00:00

abstract：:Purpose: Few large-scale population-based studies have adequately examined the relationships between steroid hormones, health status and physical fitness. The purpose of the study was to describe the relationship of serum basal endogenous steroid hormones (testosterone, TES; empirical free testosterone, EFT; cortisol,...

journal_title：Frontiers in physiology

authors： Gagnon SS,Nindl BC,Vaara JP,Santtila M,Häkkinen K,Kyröläinen H

更新日期：2018-07-27 00:00:00

abstract：:Introduction: Heart Rate Variability (HRV) and Pulse Rate Variability (PRV), are non-invasive techniques for monitoring changes in the cardiac cycle. Both techniques have been used for assessing the autonomic activity. Although highly correlated in healthy subjects, differences in HRV and PRV have been observed under ...

journal_title：Frontiers in physiology

authors： Mejía-Mejía E,Budidha K,Abay TY,May JM,Kyriacou PA

更新日期：2020-07-23 00:00:00

abstract：:The mDurance® system is an innovative digital tool that combines wearable surface electromyography (sEMG), mobile computing and cloud analysis to streamline and automatize the assessment of muscle activity. The tool is particularly devised to support clinicians and sport professionals in their daily routines, as an as...

journal_title：Frontiers in physiology

authors： Molina-Molina A,Ruiz-Malagón EJ,Carrillo-Pérez F,Roche-Seruendo LE,Damas M,Banos O,García-Pinillos F

更新日期：2020-11-27 00:00:00

abstract：:Octopuses (Octopus vulgaris) are generally considered to possess extraordinary cognitive abilities including the ability to successfully perform in a serial reversal learning task. During reversal learning, an animal is presented with a discrimination problem and after reaching a learning criterion, the signs of the s...

journal_title：Frontiers in physiology

authors： Bublitz A,Weinhold SR,Strobel S,Dehnhardt G,Hanke FD

更新日期：2017-02-07 00:00:00

abstract：:Nitric oxide serves essential roles in normal vascular physiology, but paradoxically contributes to vascular pathology in disease. During brain ischemia, aberrant nitric oxide levels can cause cellular injury through induction of nitrosative/oxidative stress and post-translational activation of matrix-metalloproteinas...

journal_title：Frontiers in physiology

authors： Underly RG,Shih AY

更新日期：2021-01-11 00:00:00

abstract：:Na(+)/Ca(2+) exchanger (NCX) proteins extrude Ca(2+) from the cell to maintain cellular homeostasis. Since NCX proteins contribute to numerous physiological and pathophysiological events, their pharmacological targeting has been desired for a long time. This intervention remains challenging owing to our poor understan...

journal_title：Frontiers in physiology

authors： Giladi M,Tal I,Khananshvili D

更新日期：2016-02-09 00:00:00

abstract：:Cotton rats are one of the experimental rodents used for testing different infectious and non-infectious diseases, including gastrointestinal tract pathology. However, their intestinal morphological characteristics are still poorly understood. Here, we clarified the anatomical and histological characteristics of the c...

journal_title：Frontiers in physiology

authors： Chuluunbaatar T,Ichii O,Nakamura T,Irie T,Namba T,Islam MR,Otani Y,Masum MA,Okamatsu-Ogura Y,Elewa YHA,Kon Y

更新日期：2020-10-26 00:00:00

abstract：:Intravascular hemolysis occurs in hereditary, acquired, and iatrogenic hemolytic conditions but it could be also a normal physiological process contributing to intercellular signaling. New evidence suggests that intravascular hemolysis and the associated release of adenosine triphosphate (ATP) may be an important mech...

journal_title：Frontiers in physiology

authors： Grygorczyk R,Orlov SN

更新日期：2017-12-22 00:00:00

abstract：:Prior peripheral hypoxia induced via remote ischemic preconditioning (IPC) can improve physical performance in male athletes through improved O2 delivery and utilization. Since females may have an innate protective mechanism against ischemia-reperfusion injury, and since muscle metabolism during contraction differs be...

journal_title：Frontiers in physiology

authors： Paradis-Deschênes P,Joanisse DR,Billaut F

更新日期：2017-01-05 00:00:00

abstract：:The "Woody" or "Wooden" breast disease is a severe myopathy of pectoralis major muscle recently identified within rapidly growing broiler lines all around the world with a prevalence rate around 20%, or even higher. Although of significant ethical and economic impact, little is known regarding the structural and funct...

journal_title：Frontiers in physiology

authors： Liu J,Puolanne E,Schwartzkopf M,Arner A

更新日期：2020-04-09 00:00:00

abstract：:To fully unravel the ixodid ticks' role as vectors of viral pathogens, their susceptibility to new control measures, and their ability to develop acaricide resistance, acclimatization of ticks under laboratory conditions is greatly needed. However, the unique and complicated feeding behavior of these ticks compared to...

journal_title：Frontiers in physiology

authors： Talactac MR,Hernandez EP,Fujisaki K,Tanaka T

更新日期：2018-12-04 00:00:00

abstract：:3-iodothyronamine (T1AM) is an endogenous amine, that has been detected in many rodent tissues, and in human blood. It has been hypothesized to derive from thyroid hormone metabolism, but this hypothesis still requires validation. T1AM is not a ligand for nuclear thyroid hormone receptors, but stimulates with nanomola...

journal_title：Frontiers in physiology

authors： Zucchi R,Accorroni A,Chiellini G

更新日期：2014-10-16 00:00:00

abstract：:Unlike most excitable cells, certain syncytial smooth muscle cells are known to exhibit spontaneous action potentials of varying shapes and sizes. These differences in shape are observed even in electrophysiological recordings obtained from a single cell. The origin and physiological relevance of this phenomenon are c...

journal_title：Frontiers in physiology

authors： Appukuttan S,Padmakumar M,Young JS,Brain KL,Manchanda R

更新日期：2018-09-20 00:00:00

abstract：:Acute beer or alcohol ingestion reduces arterial stiffness, but the dose required to reduce arterial stiffness is unclear. Therefore, this study aimed to determine the acute effects of ingesting various amounts of beer on arterial stiffness in healthy men. Nine men (20-22 years) participated, in eight trials in random...

journal_title：Frontiers in physiology

authors： Nishiwaki M,Yamaguchi T,Nishida R,Matsumoto N

更新日期：2020-08-28 00:00:00

abstract：:As verbal encouragement (VE) is used in high intensity functional exercise testing, this randomized controlled crossover study aimed at investigating whether VE affects high intensity functional strength and endurance performance testing. We further examined between-day variability of high intensity functional strengt...

journal_title：Frontiers in physiology

authors： Engel FA,Faude O,Kölling S,Kellmann M,Donath L

更新日期：2019-04-25 00:00:00

abstract：:The extensive literature dealing with the Golgi system emphasizes its role in protein secretion and modification, usually without specifying from which evolutionary ancient cell physiological necessity such secretion originated. Neither does it specify which functional requirements the secreted proteins must meet. Fro...

journal_title：Frontiers in physiology

authors： De Loof A,Schoofs L

更新日期：2020-10-15 00:00:00

abstract：:The liver was among the first organs in which connexin proteins have been identified. Hepatocytes harbor connexin32 and connexin26, while non-parenchymal liver cells typically express connexin43. Connexins give rise to hemichannels, which dock with counterparts on adjacent cells to form gap junctions. Both hemichannel...

journal_title：Frontiers in physiology

authors： Maes M,Decrock E,Cogliati B,Oliveira AG,Marques PE,Dagli ML,Menezes GB,Mennecier G,Leybaert L,Vanhaecke T,Rogiers V,Vinken M

更新日期：2014-01-10 00:00:00

abstract：:Before they develop competent endothermy, mammals and birds are sensitive to fluctuating temperature. It follows that early life thermal environment can trigger changes to the ontogeny of thermoregulatory control. At the ecological level, we have incomplete knowledge of how such responses affect temperature tolerance ...

journal_title：Frontiers in physiology

authors： Nord A,Giroud S

更新日期：2020-05-25 00:00:00

abstract：:To determine the level of hypoxia from which muscle activation (MA) is reduced during incremental exercise to exhaustion (IE), and the role played by PIO2 in this process, ten volunteers (21 ± 2 years) performed four IE in severe acute hypoxia (SAH) (PIO2 = 73 mmHg). Upon exhaustion, subjects were asked to continue ex...

journal_title：Frontiers in physiology

authors： Torres-Peralta R,Losa-Reyna J,Morales-Alamo D,González-Izal M,Pérez-Suárez I,Ponce-González JG,Izquierdo M,Calbet JA

更新日期：2016-08-17 00:00:00

abstract：:Somatostatin (SST) is a regulatory peptide and acts as an endogenous inhibitory regulator of the secretory and proliferative responses of target cells. SST's actions are mediated by a family of seven transmembrane domain G protein-coupled receptors that comprise five distinct subtypes (SSTR1-5). SSTR5 is one of the ma...

journal_title：Frontiers in physiology

authors： Zhou G,Sinnett-Smith J,Liu SH,Yu J,Wu J,Sanchez R,Pandol SJ,Abrol R,Nemunaitis J,Rozengurt E,Brunicardi FC

更新日期：2014-06-25 00:00:00

abstract：:Overconsumption of fructose leads to metabolic syndrome as a result of hypertension, insulin resistance, and hyperlipidemia. In this study, the renal function of animals submitted to high fructose intake was analyzed from weaning to adulthood using in vivo and ex vivo methods, being compared with a normal control grou...

journal_title：Frontiers in physiology

authors： Yokota R,Ronchi FA,Fernandes FB,Jara ZP,Rosa RM,Leite APO,Fiorino P,Farah V,do Nascimento NRF,Fonteles MC,Casarini DE

更新日期：2018-10-10 00:00:00

abstract：:Comparison of genomic sequences from diverse vertebrate species has revealed numerous highly conserved regions that do not appear to encode proteins or functional RNAs. Often these "conserved non-coding elements," or CNEs, can direct gene expression to specific tissues in transgenic models, demonstrating they have reg...

journal_title：Frontiers in physiology

authors： Turner EE,Cox TC

更新日期：2014-01-21 00:00:00

abstract：:Epilepsy is one of the most common disorders of the brain. Clinically, to corroborate an epileptic seizure-like symptom and to find the seizure localization, electroencephalogram (EEG) data are often visually examined by a clinical doctor to detect the presence of epileptiform discharges. Epileptiform discharges are t...

journal_title：Frontiers in physiology

authors： Li Q,Gao J,Zhang Z,Huang Q,Wu Y,Xu B

更新日期：2020-08-05 00:00:00

abstract：:Telomeres are genomic complex at the end of chromosomes that protects the DNA and telomere length (TL) is related to several age-related diseases, lifespan, and cancer. On the other hand, cancer is a multifactorial disease that is responsible for reduce the quality of life and kills millions of people every year. Both...

journal_title：Frontiers in physiology

authors： Nomikos NN,Nikolaidis PT,Sousa CV,Papalois AE,Rosemann T,Knechtle B

更新日期：2018-12-18 00:00:00

abstract：:Background: Substantial research has been done on the impact of carbohydrate and fat availability on endurance exercise adaptation, though its role in the acute adaptive response to resistance exercise has yet to be fully characterized. Purpose: We aimed to assess the effects of a pre-resistance exercise isocaloric mi...

journal_title：Frontiers in physiology

authors： Knuiman P,Hopman MTE,Wouters JA,Mensink M

更新日期：2018-01-26 00:00:00