Exercise, Telomeres, and Cancer: "The Exercise-Telomere Hypothesis".

abstract：:Many studies have investigated the physiological response to microgravity in both astronauts and animals. However, while space agencies have sought to deploy more women on their missions; animal models rarely include females studies or comparisons between males and females. Therefore, we exposed adult female rats to 2...

journal_title：Frontiers in physiology

authors： Semple C,Riveros D,Nagy JA,Rutkove SB,Mortreux M

更新日期：2020-04-03 00:00:00

abstract：:The spawning migration of the European eel is an extensive journey over 5000 to 7000 km from the European coast to the Sargasso Sea. Eels do not feed during this journey and on-board fuels must be sufficient to support the journey of 3.5 to 6 month, as well as sexual maturation and the spawning activity. Swimming of e...

journal_title：Frontiers in physiology

authors： Pelster B

更新日期：2015-01-05 00:00:00

abstract：:The earliest humans relied on large quantities of metabolic energy from the oxidation of fatty acids to develop larger brains and bodies, prevent and reduce disease risk, extend longevity, in addition to other benefits. This was enabled through the consumption of a high fat and low-carbohydrate diet (LCD). Increased f...

journal_title：Frontiers in physiology

authors： Maffetone P,Laursen PB

更新日期：2020-04-02 00:00:00

abstract：:Most sense organs of arthropods are ensconced in small exoskeletal compartments that hinder direct access to plasma membranes. We have developed a method for exposing live sensory and supporting cells in such structures. The technique uses a viscous light cured resin to embed and support the structure, which is then s...

journal_title：Frontiers in physiology

authors： Kay AR,Raccuglia D,Scholte J,Sivan-Loukianova E,Barwacz CA,Armstrong SR,Guymon CA,Nitabach MN,Eberl DF

更新日期：2016-09-12 00:00:00

abstract：:Bioenergetic profiling of cancer cells is of great potential because it can bring forward new and effective therapeutic strategies along with early diagnosis. Metabolic Control Analysis (MCA) is a methodology that enables quantification of the flux control exerted by different enzymatic steps in a metabolic network th...

journal_title：Frontiers in physiology

authors： Kaambre T,Chekulayev V,Shevchuk I,Tepp K,Timohhina N,Varikmaa M,Bagur R,Klepinin A,Anmann T,Koit A,Kaldma A,Guzun R,Valvere V,Saks V

更新日期：2013-06-28 00:00:00

abstract：Background:Angiotensin II (Ang II) could promote the development of atrial fibrosis in atrial fibrillation (AF). Apelin can inhibit the occurrence of myocardial fibrosis. However, the effect of apelin on Ang II-induced atrial fibrosis and subsequent AF still remains unknown. Objective:In the present study, we examined...

journal_title：Frontiers in physiology

authors： Lv W,Zhang L,Cheng X,Wang H,Qin W,Zhou X,Tang B

更新日期：2020-11-19 00:00:00

abstract：:The analysis of human brain functional networks is achieved by computing functional connectivity indices reflecting phase coupling and interactions between remote brain regions. In magneto- and electroencephalography, the most frequently used functional connectivity indices are constructed based on Fourier-based cross...

journal_title：Frontiers in physiology

authors： La Rocca D,Wendt H,van Wassenhove V,Ciuciu P,Abry P

更新日期：2021-01-07 00:00:00

abstract：:Recent efforts to ensure the reliability of computational model-based predictions in healthcare, such as the ASME V&V40 Standard, emphasize the importance of uncertainty quantification (UQ) and sensitivity analysis (SA) when evaluating computational models. UQ involves empirically determining the uncertainty in model ...

journal_title：Frontiers in physiology

authors： Pathmanathan P,Cordeiro JM,Gray RA

更新日期：2019-06-26 00:00:00

abstract：:Muscle quality and the physiological condition of fish are affected greatly by the culture environment. In aquaculture ponds, a bio-floating bed planted with vegetation is often used to improve water quality. This study investigated the growth and muscle quality of grass carp (Ctenopharyngodon idellus) cultured in pon...

journal_title：Frontiers in physiology

authors： Zhang X,Wang J,Tang R,He X,Li L,Takagi Y,Li D

更新日期：2019-05-31 00:00:00

abstract：:Human pluripotent stem cells (hPSCs) represent a new and exciting field in modern medicine, now the focus of many researchers and media outlets. The hype is well-earned because of the potential of stem cells to contribute to disease modeling, drug screening, and even therapeutic approaches. In this review, we focus fi...

journal_title：Frontiers in physiology

authors： Martinez Y,Dubois-Dauphin M,Krause KH

更新日期：2012-03-19 00:00:00

abstract：:Intermittent hypoxia (IH), characterized as cyclic episodes of short-period hypoxia followed by normoxia, occurs in many physiological and pathophysiological conditions such as pregnancy, athlete, obstructive sleep apnea, and asthma. Hypoxia can induce autophagy, which is activated in response to protein aggregates, i...

journal_title：Frontiers in physiology

authors： Chang JC,Hu WF,Lee WS,Lin JH,Ting PC,Chang HR,Shieh KR,Chen TI,Yang KT

更新日期：2019-08-07 00:00:00

abstract：:Coral reef communities are undergoing marked declines due to a variety of stressors including disease. The sea fan coral, Gorgonia ventalina, is a tractable study system to investigate mechanisms of immunity to a naturally occurring pathogen. Functional studies in Gorgonia ventalina immunity indicate that several key ...

journal_title：Frontiers in physiology

authors： Burge CA,Mouchka ME,Harvell CD,Roberts S

更新日期：2013-07-25 00:00:00

abstract：:The purpose of this study was to analyze the correlation between decompression-related physiological stress markers, given by inflammatory processes and immune system activation and changes in Heart Rate Variability, evaluating whether Heart Rate Variability can be used to estimate the physiological stress caused by t...

journal_title：Frontiers in physiology

authors： Schirato SR,El-Dash I,El-Dash V,Bizzarro B,Marroni A,Pieri M,Cialoni D,Chaui-Berlinck JG

更新日期：2020-07-03 00:00:00

abstract：:Background: Whole-body electromyostimulation (WB-EMS) gained increasing interest in sports within recent years. However, few intervention studies have examined the effects of WB-EMS on trained subjects in comparison to conventional strength training. Objective: The aim of the present mini-meta-analysis of 5 recently c...

journal_title：Frontiers in physiology

authors： Wirtz N,Dörmann U,Micke F,Filipovic A,Kleinöder H,Donath L

更新日期：2019-11-08 00:00:00

abstract：:Background: Hypoxia represents both an outcome of cardiopulmonary diseases and a trigger for severe pulmonary complications as pulmonary hypertension. Because nitric oxide (NO) is a critical mediator in the development of pulmonary hypertension, the modulators of its downstream function may become target of pharmacolo...

journal_title：Frontiers in physiology

authors： Nydegger C,Martinelli C,Di Marco F,Bulfamante G,von Segesser L,Tozzi P,Samaja M,Milano G

更新日期：2018-03-27 00:00:00

abstract：:Odontoblast cells generated from human dental pulp stem/progenitor cells (hDPSCs) secrete reparative dentin in responds to an injury. Endogenous Wnt signaling is also activated during this process, and these Wnt-activated cells are responsible for the following repair response. R-spondin 2 (Rspo2) is a potent stem cel...

journal_title：Frontiers in physiology

authors： Gong Y,Yuan S,Sun J,Wang Y,Liu S,Guo R,Dong W,Li R

更新日期：2020-08-07 00:00:00

abstract：:In our digitized society, advanced information and communication technology and highly interactive work environments impose high demands on cognitive capacity. Optimal workload conditions are important for assuring employee's health and safety of other persons. This is particularly relevant in safety-critical occupati...

journal_title：Frontiers in physiology

authors： Radüntz T,Fürstenau N,Mühlhausen T,Meffert B

更新日期：2020-04-21 00:00:00

abstract：:Introduction: Although short-term (approximately 10-min) fatiguing DP has been reported not to alter the joint kinematics or displacement of the centre of mass (COM) of high-level skiers, we hypothesize that prolonged DP does change these kinematics, since muscular strength is impaired following endurance events lasti...

journal_title：Frontiers in physiology

authors： Zoppirolli C,Bortolan L,Stella F,Boccia G,Holmberg HC,Schena F,Pellegrini B

更新日期：2018-07-25 00:00:00

abstract：BACKGROUND:During caesarean section spinal anesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine. Phenylephrine is however reported to reduce the near infrared spectroscopy-determined frontal lobe oxygenation (ScO2) but whether that is the case for patients expo...

journal_title：Frontiers in physiology

authors： Foss VT,Christensen R,Rokamp KZ,Nissen P,Secher NH,Nielsen HB

更新日期：2014-03-03 00:00:00

abstract：:Current cardiac drug safety assessments focus on hERG channel block and QT prolongation for evaluating arrhythmic risks, whereas the optogenetic approach focuses on the action potential (AP) waveform generated by a monolayer of human cardiomyocytes beating synchronously, thus assessing the contribution of several ion ...

journal_title：Frontiers in physiology

authors： Björk S,Ojala EA,Nordström T,Ahola A,Liljeström M,Hyttinen J,Kankuri E,Mervaala E

更新日期：2017-11-02 00:00:00

abstract：:Within the vasculature Kv7 channels are key regulators of basal tone and contribute to a variety of receptor mediated vasorelaxants. The Kv7.4 isoform, abundant within the vasculature, is key to these processes and was recently shown to have an obligatory requirement of G-protein βγ subunits for its voltage dependent ...

journal_title：Frontiers in physiology

authors： Greenwood IA,Stott JB

更新日期：2020-01-14 00:00:00

abstract：:Percutaneous edge-to-edge mitral valve (MV) repair using MitraClip has been recently established as a treatment option for patients with heart failure and functional mitral regurgitation (MR), which significantly expands the number of patients that can be treated with this device. This study aimed to quantify the morp...

journal_title：Frontiers in physiology

authors： Caballero A,Mao W,McKay R,Hahn RT,Sun W

更新日期：2020-05-07 00:00:00

abstract：:The present study aims (1) to evaluate ratings of perceived exertion (RPE) and corresponding intensities during a maximal graded cycling test and (2) to determine the effects of 6 weeks of supramaximal cycling exercise (SCE) intervention on RPE and associated physiological factors in young and older sedentary groups. ...

journal_title：Frontiers in physiology

authors： Jabbour G,Majed L

更新日期：2018-10-25 00:00:00

abstract：:Skeletal muscles are the largest cells in the body and are one of the few syncytial ones. There is a longstanding belief that a given nucleus controls a defined volume of cytoplasm, so when a muscle grows (hypertrophy) or shrinks (atrophy), the number of myonuclei change accordingly. This phenomenon is known as the "m...

journal_title：Frontiers in physiology

authors： Schwartz LM

更新日期：2019-01-25 00:00:00

abstract：:Aims: Simultaneous measurement of right (RV) and left ventricle (LV) myocardial blood flow (MBF), oxygen extraction fraction (OEF), and oxygen consumption (MVO2) non-invasively in humans would provide new possibilities to understand cardiac physiology and different patho-physiological states. Methods: We developed and...

journal_title：Frontiers in physiology

authors： Kudomi N,Kalliokoski KK,Oikonen VJ,Han C,Kemppainen J,Sipilä HT,Knuuti J,Heinonen IHA

更新日期：2019-06-19 00:00:00

abstract：:Arrhythmogenic cardiomyopathy (AC) has originally been described as a disorder characterized by fibrofatty replacement of the myocardium, primarily of the right ventricle (RV), and ventricular tachyarrhythmias, sudden death, and at a late stage progressive heart failure. Arrhythmogenic right ventricular dysplasia or c...

journal_title：Frontiers in physiology

authors： Hauer RN,Cox MG,Groeneweg JA

更新日期：2012-09-17 00:00:00

abstract：Background:The development of childhood motor competence demonstrates a high degree of inter-individual variation. Some children's competence levels increase whilst others' competence levels remain unchanged or even decrease over time. However, few studies have examined this developmental change in motor competence acr...

journal_title：Frontiers in physiology

authors： Coppens E,Bardid F,Deconinck FJA,Haerens L,Stodden D,D'Hondt E,Lenoir M

更新日期：2019-10-02 00:00:00

abstract：:Purpose: To examine the effects of deceptively aggressive bike pacing on performance, pacing, and associated physiological and perceptual responses during simulated sprint-distance triathlon. Methods: Ten non-elite, competitive male triathletes completed three simulated sprint-distance triathlons (0.75 km swim, 500 kJ...

journal_title：Frontiers in physiology

authors： Taylor D,Smith MF

更新日期：2017-01-24 00:00:00

abstract：:Knowledge of the lung vessel morphology in healthy subjects is necessary to improve our understanding about the functional network of the lung and to recognize pathologic deviations beyond the normal inter-subject variation. Established values of normal lung morphology have been derived from necropsy material of only ...

journal_title：Frontiers in physiology

authors： Pienn M,Burgard C,Payer C,Avian A,Urschler M,Stollberger R,Olschewski A,Olschewski H,Johnson T,Meinel FG,Bálint Z

更新日期：2018-04-10 00:00:00

abstract：:Deep learning (DL) has attracted the attention of computational toxicologists as it offers a potentially greater power for in silico predictive toxicology than existing shallow learning algorithms. However, contradicting reports have been documented. To further explore the advantages of DL over shallow learning, we co...

journal_title：Frontiers in physiology

authors： Idakwo G,Thangapandian S,Luttrell J 4th,Zhou Z,Zhang C,Gong P

更新日期：2019-08-13 00:00:00