Scalable and Accurate ECG Simulation for Reaction-Diffusion Models of the Human Heart.

abstract：:The pre-occlusal eruption brings the molars into functional occlusion and initiates tensional strains during mastication. We hypothesized that upon establishment of occlusal contact, the periodontal ligament (PDL) undergoes cell and extracellular matrix maturation to adapt to this mechanical function. The PDL of 12 Wi...

journal_title：Frontiers in physiology

authors： Denes BJ,Ait-Lounis A,Wehrle-Haller B,Kiliaridis S

更新日期：2020-03-05 00:00:00

abstract：:Antineoplastic drugs can be associated with several side effects, including cardiovascular toxicity (CTX). Biochemical studies have identified multiple mechanisms of CTX. Chemoterapeutic agents can alter redox homeostasis by increasing the production of reactive oxygen species (ROS) and reactive nitrogen species RNS. ...

journal_title：Frontiers in physiology

authors： Varricchi G,Ameri P,Cadeddu C,Ghigo A,Madonna R,Marone G,Mercurio V,Monte I,Novo G,Parrella P,Pirozzi F,Pecoraro A,Spallarossa P,Zito C,Mercuro G,Pagliaro P,Tocchetti CG

更新日期：2018-03-07 00:00:00

abstract：:Background and Purpose: Store-operated calcium entry (SOCE) is an important physiological phenomenon that extensively mediates intracellular calcium ion (Ca2+) load. It has been previously found in myocytes isolated from neonatal or diseased hearts. We aimed to determine its existence, molecular nature in undiseased h...

journal_title：Frontiers in physiology

authors： Wen H,Zhao Z,Fefelova N,Xie LH

更新日期：2018-12-13 00:00:00

abstract：:The central dogma of molecular biology has come under scrutiny in recent years. Here, we reviewed high-throughput mRNA and protein expression data of Escherichia coli, Saccharomyces cerevisiae, and several mammalian cells. At both single cell and population scales, the statistical comparisons between the entire transc...

journal_title：Frontiers in physiology

authors： Piras V,Tomita M,Selvarajoo K

更新日期：2012-11-23 00:00:00

abstract：:Background: Tissue availability of polyunsaturated fatty acids (PUFA) depends on several factors, including dietary intake, physical exercise, genetic variation, and metabolic turnover. However, there is limited evidence whether running training activity per se may influence indices associated with PUFA metabolism suc...

journal_title：Frontiers in physiology

authors： Davinelli S,Corbi G,Righetti S,Casiraghi E,Chiappero F,Martegani S,Pina R,De Vivo I,Simopoulos AP,Scapagnini G

更新日期：2019-04-26 00:00:00

abstract：:Pulmonary edema (PE) is an issue widely noted in acute exposure to hypoxia as seen in high altitude climbers, yet the etiology of this is not defined. Previous studies in rats showed that both hypoxia and strong sympathetic activation may induce PE. As acute exposure to hypoxia is accompanied by sympathetic activation...

journal_title：Frontiers in physiology

authors： Bölter C,Gabriel P,Appelt P,Salameh A,Schierle K,Rassler B

更新日期：2019-07-05 00:00:00

abstract：:Lactic acid and short chain fatty acids (SCFAs) produced by vaginal microbiota have reported antimicrobial and immune modulatory activities indicating their potential as biomarkers of disease and/or disease susceptibility. In asymptomatic women of reproductive-age the vaginal microbiota is comprised of lactic acid-pro...

journal_title：Frontiers in physiology

authors： Aldunate M,Srbinovski D,Hearps AC,Latham CF,Ramsland PA,Gugasyan R,Cone RA,Tachedjian G

更新日期：2015-06-02 00:00:00

abstract：:The development of IBS symptoms - altered bowel function and abdominal cramping in a subset of adult subjects exposed to severe enteric infections opened up an unprecedented opportunity to understand the etiology of this poorly understood disorder. Perhaps, for the reasons that these symptoms follow a severe enteric i...

journal_title：Frontiers in physiology

authors： Sarna SK

更新日期：2011-08-23 00:00:00

abstract：:We have isolated dental pulp cells (DPCs) from three healthy (hDPCs) and three carious (cDPCs) donors and shown that compared to hDPCs cells isolated from superficial carious lesions show higher clonogenic potential; show an equivalent proportion of cells with putative stem cell surface markers; show enhanced matrix m...

journal_title：Frontiers in physiology

authors： Alkharobi H,Beattie J,Meade J,Devine D,El-Gendy R

更新日期：2017-04-28 00:00:00

abstract：:Objective: Ventricular remodeling is considered the basis of heart failure and is involved in myocardial fibrosis. This study aimed to assess perindopril and a galectin-3 inhibitor (modified citrus pectin, MCP) for their effects on ventricular remodeling and myocardial fibrosis in rabbits with ischemic heart failure. ...

journal_title：Frontiers in physiology

authors： Li S,Li S,Hao X,Zhang Y,Deng W

更新日期：2019-03-22 00:00:00

abstract：:Woody breast (WB) myopathy in modern broilers is causing major meat quality issues and consumer complaints. The poultry industry is sorting out WB filets through the inconsistent manual hand-palpation method. Bioelectrical impedance analysis (BIA) method was evaluated as a rapid and objective WB detection method. Fres...

journal_title：Frontiers in physiology

authors： Morey A,Smith AE,Garner LJ,Cox MK

更新日期：2020-07-10 00:00:00

abstract：:Moonlighting proteins are a subset of multifunctional proteins characterized by their multiple, independent, and unrelated biological functions. We recently set up a large-scale identification of moonlighting proteins using a protein-protein interaction (PPI) network approach. We established that 3% of the current hum...

journal_title：Frontiers in physiology

authors： Zanzoni A,Chapple CE,Brun C

更新日期：2015-06-23 00:00:00

abstract：:Purpose: To examine the effects of deceptively aggressive bike pacing on performance, pacing, and associated physiological and perceptual responses during simulated sprint-distance triathlon. Methods: Ten non-elite, competitive male triathletes completed three simulated sprint-distance triathlons (0.75 km swim, 500 kJ...

journal_title：Frontiers in physiology

authors： Taylor D,Smith MF

更新日期：2017-01-24 00:00:00

abstract：:In order to investigate protective roles of dietary selenium yeast (SY) and tea polyphenols (TPs) on growth of juvenile Wuchang bream (Megalobrama amblycephala) and its resistance under ammonia stress, juvenile Wuchang bream were randomly assigned into four groups: a control group fed basal diets and three treatment g...

journal_title：Frontiers in physiology

authors： Guo H,Lin W,Hou J,Wang L,Zhang D,Wu X,Li L,Li D

更新日期：2018-10-02 00:00:00

abstract：:Human diseases have been investigated in the context of single genes as well as complex networks of genes. Though single gene approaches have been extremely successful in the past, most human diseases are complex and better characterized by multiple interacting genes commonly known as networks or pathways. With the ad...

journal_title：Frontiers in physiology

authors： Sahoo D

更新日期：2012-07-23 00:00:00

abstract：:This study evaluated the effects of continuous and intermittent blood flow restriction (BFR) with 70% of full arterial occlusion pressure on bar velocity during the bench press exercise against a wide range of resistive loads. Eleven strength-trained males (age: 23.5 ± 1.4 years; resistance training experience: 2.8 ± ...

journal_title：Frontiers in physiology

authors： Wilk M,Gepfert M,Krzysztofik M,Stastny P,Zajac A,Bogdanis GC

更新日期：2020-11-27 00:00:00

abstract：:In aged subjects, late-onset Alzheimer's disease (LOAD) starts in the lateral entorhinal allocortex where a failure of clearance mechanisms triggers an accumulation of neurotoxic amyloid-β42 oligomers (Aβ42-os). In neurons and astrocytes, Aβ42-os enhance the transcription of Aβ precursor protein (APP) and β-secretase/...

journal_title：Frontiers in physiology

authors： Chiarini A,Armato U,Liu D,Dal Prà I

更新日期：2016-04-26 00:00:00

abstract：:In this paper, we computationally generate hypotheses for dose-finding studies in the context of desynchronizing neuromodulation techniques. Abnormally strong neuronal synchronization is a hallmark of several brain disorders. Coordinated Reset (CR) stimulation is a spatio-temporally patterned stimulation technique tha...

journal_title：Frontiers in physiology

authors： Manos T,Zeitler M,Tass PA

更新日期：2018-04-12 00:00:00

abstract：:The main goal of this study was to assess the impact of the cambered bar (CB) during the bench press exercise on power output and bar velocity when compared to a standard bar (SB). Ten healthy strength-trained men (age = 27.9 ± 3.7 years; body mass = 90.1 ± 12.5 kg; resistance training experience = 6.5 ± 2.7 years; be...

journal_title：Frontiers in physiology

authors： Krzysztofik M,Zajac A,Żmijewski P,Wilk M

更新日期：2020-10-20 00:00:00

abstract：:Patients undergoing hyperbaric oxygen therapy and divers engaged in underwater activity are at risk of central nervous system oxygen toxicity. An algorithm for predicting CNS oxygen toxicity in active underwater diving has been published previously, but not for humans at rest. Using a procedure similar to that employe...

journal_title：Frontiers in physiology

authors： Aviner B,Arieli R,Yalov A

更新日期：2020-08-17 00:00:00

abstract：:Accurate evaluation of the appearance of QTc sex differences during childhood and adolescence is intricate. Inter-subject differences of individual QT/RR patterns make generic heart rate corrections inaccurate because of fast resting heart rates in children. The study investigated 527 healthy children and adolescents ...

journal_title：Frontiers in physiology

authors： Andršová I,Hnatkova K,Helánová K,Šišáková M,Novotný T,Kala P,Malik M

更新日期：2019-08-02 00:00:00

abstract：:In the chronic stage of myocardial infarction, a significant number of patients develop life-threatening ventricular tachycardias (VT) due to the arrhythmogenic nature of the remodeled myocardium. Radiofrequency ablation (RFA) is a common procedure to isolate reentry pathways across the infarct scar that are responsib...

journal_title：Frontiers in physiology

authors： Lopez-Perez A,Sebastian R,Izquierdo M,Ruiz R,Bishop M,Ferrero JM

更新日期：2019-05-15 00:00:00

abstract：:The aim of this study is to detect the effects of C60 fullerenes, which possess pronounced antioxidant properties, in comparison with the actions of the known exogenous antioxidants N-acetylcysteine (NAC) and β-Alanine in terms of exercise tolerance and contractile property changes of the m. triceps surae (TS) during ...

journal_title：Frontiers in physiology

authors： Vereshchaka IV,Bulgakova NV,Maznychenko AV,Gonchar OO,Prylutskyy YI,Ritter U,Moska W,Tomiak T,Nozdrenko DM,Mishchenko IV,Kostyukov AI

更新日期：2018-05-15 00:00:00

abstract：:As arteries become stiffer with aging, reflected waves move faster and augment late systolic pressure. Few studies have described the age-related changes in both peripheral and central systolic blood pressures in populations. We investigated the age dependency of peripheral (pSBP) and central (cSBP) systolic pressure ...

journal_title：Frontiers in physiology

authors： Wojciechowska W,Li Y,Stolarz-Skrzypek K,Kawecka-Jaszcz K,Staessen JA,Wang JG,European Project on Genes in Hypertension and the JingNing Study Investigators.

更新日期：2012-06-15 00:00:00

abstract：Background:The development of childhood motor competence demonstrates a high degree of inter-individual variation. Some children's competence levels increase whilst others' competence levels remain unchanged or even decrease over time. However, few studies have examined this developmental change in motor competence acr...

journal_title：Frontiers in physiology

authors： Coppens E,Bardid F,Deconinck FJA,Haerens L,Stodden D,D'Hondt E,Lenoir M

更新日期：2019-10-02 00:00:00

abstract：:Renal fibrosis is characterized by progressive accumulation of extracellular matrix (ECM) proteins, resulting in loss of organ function and eventually requiring renal replacement therapy. Unfortunately, no efficacious treatment options are available to halt renal fibrosis and translational models to test pharmacologic...

journal_title：Frontiers in physiology

authors： Stribos EGD,Seelen MA,van Goor H,Olinga P,Mutsaers HAM

更新日期：2017-12-12 00:00:00

abstract：:Patients undergoing the complex treatment for hematological malignancies are exposed to a high physiological and psychological distress inducing fatigue and physical inactivity. In line with cancer-related metabolic changes patients are predisposed for skeletal muscle mass loss that leads to a functional decline, affe...

journal_title：Frontiers in physiology

authors： Schink K,Reljic D,Herrmann HJ,Meyer J,Mackensen A,Neurath MF,Zopf Y

更新日期：2018-12-18 00:00:00

abstract：:The microbes in the gastrointestinal tract are separated from the host by a single layer of intestinal epithelial cells (IECs) that plays pivotal roles in maintaining homeostasis by absorbing nutrients and providing a physical and immunological barrier to potential pathogens. Preservation of homeostasis requires the c...

journal_title：Frontiers in physiology

authors： Burgueño JF,Fritsch J,Santander AM,Brito N,Fernández I,Pignac-Kobinger J,Conner GE,Abreu MT

更新日期：2019-12-12 00:00:00

abstract：:Advances in the development of voltage sensitive dyes and Ca(2+) sensors in combination with innovative microscopy techniques allowed researchers to perform functional measurements with an unprecedented spatial and temporal resolution. At the moment, one of the shortcomings of available technologies is their incapabil...

journal_title：Frontiers in physiology

authors： Crocini C,Coppini R,Ferrantini C,Pavone FS,Sacconi L

更新日期：2014-10-20 00:00:00

abstract：:Knowledge of the lung vessel morphology in healthy subjects is necessary to improve our understanding about the functional network of the lung and to recognize pathologic deviations beyond the normal inter-subject variation. Established values of normal lung morphology have been derived from necropsy material of only ...

journal_title：Frontiers in physiology

authors： Pienn M,Burgard C,Payer C,Avian A,Urschler M,Stollberger R,Olschewski A,Olschewski H,Johnson T,Meinel FG,Bálint Z

更新日期：2018-04-10 00:00:00