Compliant Titin Isoform Content Is Reduced in Left Ventricles of Sedentary Versus Active Rats.

abstract：Context:Strength-endurance mainly depends on the power output, which is often expressed relative to the individual's maximal power capability (Pmax). However, an individual can develop the same power, but in different combinations of force and velocity (force-velocity condition). Also, at matched power output, changing...

journal_title：Frontiers in physiology

authors： Rivière JR,Peyrot N,Cross MR,Messonnier LA,Samozino P

更新日期：2020-10-09 00:00:00

abstract：:Lepidopteran species detect CO2 via a specialized organ located on the peripheral segment of the labial palps, the labial palp pit organ (LPO). Based on tracing of LPO sensory neurons targeting one distinct antennal-lobe glomerulus, Kent and her colleagues described the projections originating from the LPO in the sphi...

journal_title：Frontiers in physiology

authors： Kc P,Chu X,Kvello P,Zhao XC,Wang GR,Berg BG

更新日期：2020-03-17 00:00:00

abstract：:Background: Measuring the extent to which renal artery stenosis (RAS) alters renal haemodynamics may permit precision medicine by physiologically guided revascularization. This currently requires invasive intra-arterial pressure measurement with associated risks and is rarely performed. The present proof-of-concept st...

journal_title：Frontiers in physiology

authors： Mandaltsi A,Grytsan A,Odudu A,Kadziela J,Morris PD,Witkowski A,Ellam T,Kalra P,Marzo A

更新日期：2018-08-17 00:00:00

abstract：:We have isolated dental pulp cells (DPCs) from three healthy (hDPCs) and three carious (cDPCs) donors and shown that compared to hDPCs cells isolated from superficial carious lesions show higher clonogenic potential; show an equivalent proportion of cells with putative stem cell surface markers; show enhanced matrix m...

journal_title：Frontiers in physiology

authors： Alkharobi H,Beattie J,Meade J,Devine D,El-Gendy R

更新日期：2017-04-28 00:00:00

abstract：:This study was designed to investigate the effects of a newly synthesized carboxymethyl-glucan (CM-G) on blood pressure (BP), baroreflex sensitivity (BRS) and sympathetic vascular modulation in renovascular hypertensive rats. Male Wistar rats were divided into four groups: Sham (n = 10); 2K1C (subjected to renal arter...

journal_title：Frontiers in physiology

authors： Carvalho-Galvão A,Gadelha DDA,de Brito Alves JL,Khan BA,Castro-Gomez RJH,Cruz JC,Magnani M,Braga VA

更新日期：2018-05-23 00:00:00

abstract：:A Boolean model is a simple, discrete and dynamic model without the need to consider the effects at the intermediate levels. However, little effort has been made into constructing activation, inhibition, and protein decay networks, which could indicate the direct roles of a gene (or its synthesized protein) as an acti...

journal_title：Frontiers in physiology

authors： Chen L,Kulasiri D,Samarasinghe S

更新日期：2018-09-25 00:00:00

abstract：:Mollusk shells are products of biomineralization and possess excellent mechanical properties, and shell matrix proteins (SMPs) have important functions in shell formation. A novel SMP with a PDZ domain (PDZ-domain-containing-protein-1, PDCP-1) was identified from the shell matrices of Mytilus coruscus. In this study, ...

journal_title：Frontiers in physiology

authors： Sun Q,Jiang Y,Yan X,Fan M,Zhang X,Xu H,Liao Z

更新日期：2020-10-02 00:00:00

abstract：:The Paramisgurnus dabryanus was exposed to air to assess the changes in plasma, liver and muscle free amino acid (FAA) contents. The FAA concentrations in plasma, liver and muscle of P. dabryanus were significantly affected by aerial exposure (P < 0.05). After 12 h of aerial exposure, the plasma glutamate contents inc...

journal_title：Frontiers in physiology

authors： Zhang YL,Wang GY,Zhang ZH,Xie YY,Jin H,Dong ZR

更新日期：2019-01-29 00:00:00

abstract：:Swimming induced pulmonary edema (SIPE) is a complication that can occur during exercise with the possibility of misdiagnosis and can quickly become life threatening; however, medical literature infrequently describes SIPE. Therefore, the aim of this review was to analyse all individual cases diagnosed with SIPE as re...

journal_title：Frontiers in physiology

authors： Grünig H,Nikolaidis PT,Moon RE,Knechtle B

更新日期：2017-08-31 00:00:00

abstract：:Most sense organs of arthropods are ensconced in small exoskeletal compartments that hinder direct access to plasma membranes. We have developed a method for exposing live sensory and supporting cells in such structures. The technique uses a viscous light cured resin to embed and support the structure, which is then s...

journal_title：Frontiers in physiology

authors： Kay AR,Raccuglia D,Scholte J,Sivan-Loukianova E,Barwacz CA,Armstrong SR,Guymon CA,Nitabach MN,Eberl DF

更新日期：2016-09-12 00:00:00

abstract：:Mild cognitive impairment (MCI) is a common symptom at the baseline of early Parkinson's disease (PD) diagnosis, but the neural mechanism is unclear. To address the issue, the present study employed resting-state functional magnetic resonance imaging data of 19 drug-naïve PD patients with normal cognition (PD-NC), 10 ...

journal_title：Frontiers in physiology

authors： Wang Z,Jia X,Chen H,Feng T,Wang H

更新日期：2018-08-14 00:00:00

abstract：:Planarians undergo continuous body size remodeling under starvation or during regeneration. This process likely involves autophagy and autophagic cell death, but this hypothesis is supported by few studies. To test this hypothesis, we cloned and characterized autophagy-related gene 7 (Atg7) from the planarian Dugesia ...

journal_title：Frontiers in physiology

authors： Ma K,Zhang Y,Song G,Wu M,Chen G

更新日期：2018-09-04 00:00:00

abstract：:A water surface acts not only as an optic mirror but also as an acoustic mirror. Echolocation calls emitted by bats at low heights above water are reflected away from the bat, and hence the background clutter is reduced. Moreover, targets on the surface create an enhanced echo. Here, we formally quantified the effect ...

journal_title：Frontiers in physiology

authors： Zsebok S,Kroll F,Heinrich M,Genzel D,Siemers BM,Wiegrebe L

更新日期：2013-04-05 00:00:00

abstract：:For early prevention of cardiovascular disease, early detection and risk factor insights are necessary. The autonomic balance reflects cardiovascular risk and can be measured by heart rate variability (HRV). Therefore, our purpose is to examine associations between HRV and the energy-related biomarkers leptin and adip...

journal_title：Frontiers in physiology

authors： Van De Wielle R,Michels N

更新日期：2017-07-12 00:00:00

abstract：:The complex interactions that give rise to heart rate variability (HRV) involve coupled physiological oscillators operating over a wide range of different frequencies and length-scales. Based on the premise that interactions are key to the functioning of complex systems, the time-dependent deterministic coupling param...

journal_title：Frontiers in physiology

authors： Ticcinelli V,Stankovski T,Iatsenko D,Bernjak A,Bradbury AE,Gallagher AR,Clarkson PBM,McClintock PVE,Stefanovska A

更新日期：2017-10-13 00:00:00

abstract：:Sarcopenia is the age-related progressive loss of skeletal muscle mass and strength finally leading to poor physical performance. Impaired myogenesis contributes to the pathogenesis of sarcopenia, while mitochondrial dysfunctions are thought to play a primary role in skeletal muscle loss during aging. Here we studied ...

journal_title：Frontiers in physiology

authors： Belli R,Bonato A,De Angelis L,Mirabilii S,Ricciardi MR,Tafuri A,Molfino A,Leigheb M,Costelli P,Caruso M,Muscaritoli M,Ferraro E

更新日期：2019-07-10 00:00:00

abstract：:As a biomaterial, chitosan has been widely used in tissue engineering, wound healing, drug delivery, and other biomedical applications. It can be formulated in a variety of forms, such as powder, film, sphere, gel, and fiber. These features make chitosan an almost ideal biomaterial in cell culture applications, and ce...

journal_title：Frontiers in physiology

authors： Gao W,Lai JC,Leung SW

更新日期：2012-08-21 00:00:00

abstract：:The appearance of oxygen in the terrestrial atmosphere represented an important selective pressure for ancestral living organisms and contributed toward setting up the pace of evolutionary changes in structural and functional systems. The evolution of using oxygen for efficient energy production served as a driving fo...

journal_title：Frontiers in physiology

authors： Naudí A,Jové M,Ayala V,Portero-Otín M,Barja G,Pamplona R

更新日期：2013-12-17 00:00:00

abstract：:Aim: To investigate whether housing temperature influences rat adiposity, and the extent it is modified by diet and/or pregnancy. Housing temperature impacts on brown adipose tissue, that possess a unique uncoupling protein (UCP) 1, which, when activated by reduced ambient temperature, enables rapid heat generation. M...

journal_title：Frontiers in physiology

authors： Albustanji L,Perez GS,AlHarethi E,Aldiss P,Bloor I,Barreto-Medeiros JM,Budge H,Symonds ME,Dellschaft N

更新日期：2019-03-06 00:00:00

abstract：:Purpose: This study aimed to examine the exercise-mediated musculoskeletal recovery following hindlimb suspension (HS) in order to identify whether bone modeling and muscle hypertrophy would eventuate in a synchronized manner during recovery stage. Methods: To identify whether 2-week HS would be sufficient to induce a...

journal_title：Frontiers in physiology

authors： Song H,Cho S,Lee HY,Lee H,Song W

更新日期：2018-08-13 00:00:00

abstract：:Circadian clocks are endogenous oscillators essential for orchestrating daily rhythms in physiology, metabolism and behavior. While mouse models have been instrumental to elucidate the molecular mechanism of circadian rhythm generation, our knowledge about the molecular makeup of circadian oscillators in humans is sti...

journal_title：Frontiers in physiology

authors： Börding T,Abdo AN,Maier B,Gabriel C,Kramer A

更新日期：2019-05-09 00:00:00

abstract：:Tumor cells alter their metabolism to maintain unregulated cellular proliferation and survival, but this transformation leaves them reliant on constant supply of nutrients and energy. In addition to the widely studied dysregulated glucose metabolism to fuel tumor cell growth, accumulating evidences suggest that utiliz...

journal_title：Frontiers in physiology

authors： Ghaffari P,Mardinoglu A,Nielsen J

更新日期：2015-12-16 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle. Mitochondrial dysfunction is a well-known pathological feature of DMD. However, whether mitochondrial dysfunction occurs before muscle fiber damage in DMD pathology is not well known. Furthermore, the impact upon heterozygous femal...

journal_title：Frontiers in physiology

authors： Moore TM,Lin AJ,Strumwasser AR,Cory K,Whitney K,Ho T,Ho T,Lee JL,Rucker DH,Nguyen CQ,Yackly A,Mahata SK,Wanagat J,Stiles L,Turcotte LP,Crosbie RH,Zhou Z

更新日期：2020-06-19 00:00:00

abstract：Objective:Develop an automated approach to detect flash (<1.0 s) or prolonged (>2.0 s) capillary refill time (CRT) that correlates with clinician judgment by applying several supervised machine learning (ML) techniques to pulse oximeter plethysmography data. Materials and Methods:Data was collected in the Pediatric In...

journal_title：Frontiers in physiology

authors： Hunter RB,Jiang S,Nishisaki A,Nickel AJ,Napolitano N,Shinozaki K,Li T,Saeki K,Becker LB,Nadkarni VM,Masino AJ

更新日期：2020-10-06 00:00:00

abstract：:The use of aquatic invertebrates in biomedical research and as environmental sentinels has dramatically grown in recent decades, with an increased need in understanding of comparative pathology. The Unionids freshwater mussels are a group of worldwide distributed bivalves residing small ditches and ponds, lakes, canal...

journal_title：Frontiers in physiology

authors： Carella F,Villari G,Maio N,De Vico G

更新日期：2016-11-01 00:00:00

abstract：:Voltage-gated potassium (Kv) channels shape the action potentials of excitable cells and regulate membrane potential and ion homeostasis in excitable and non-excitable cells. With 40 known members in the human genome and a variety of homomeric and heteromeric pore-forming α subunit interactions, post-translational mod...

journal_title：Frontiers in physiology

authors： Kanda VA,Abbott GW

更新日期：2012-06-28 00:00:00

abstract：:For many hereditary disorders, although the underlying genetic mutation may be known, the molecular mechanism leading to hemolytic anemia is still unclear and needs further investigation. Previous studies revealed an increased intracellular Ca2+ in red blood cells (RBCs) from patients with sickle cell disease, thalass...

journal_title：Frontiers in physiology

authors： Hertz L,Huisjes R,Llaudet-Planas E,Petkova-Kirova P,Makhro A,Danielczok JG,Egee S,Del Mar Mañú-Pereira M,van Wijk R,Vives Corrons JL,Bogdanova A,Kaestner L

更新日期：2017-09-06 00:00:00

abstract：:Pancreatic cancer is one of the deadliest human malignancies and little progress has been achieved in its treatment over the past decades. Advances in our understanding of the biology of this disease provide new potential opportunities for treatment. Pancreatic cancer is preceded by precursor lesions, the most common ...

journal_title：Frontiers in physiology

authors： Collins MA,Pasca di Magliano M

更新日期：2014-01-21 00:00:00

abstract：:Odorant binding proteins (OBPs) are proposed to be directly required for odorant discrimination and represent potential interesting targets for pest control. In the notoriously agricultural pest Adelphocoris lineolatus, our previous functional investigation of highly expressed antennal OBPs clearly supported this view...

journal_title：Frontiers in physiology

authors： Sun L,Wei Y,Zhang DD,Ma XY,Xiao Y,Zhang YN,Yang XM,Xiao Q,Guo YY,Zhang YJ

更新日期：2016-06-01 00:00:00

abstract：:We present a first description of the distribution and characterization of epitheliocystis infections in brown trout (Salmo trutta) from the upper catchments of two major European rivers, the Rhine and the Rhone. Overall, epitheliocystis was widely distributed, with 70% of the Rhine and 67% of the Rhone sites harborin...

journal_title：Frontiers in physiology

authors： Guevara Soto M,Vaughan L,Segner H,Wahli T,Vidondo B,Schmidt-Posthaus H

更新日期：2016-04-18 00:00:00