Risk Factors for Septicemia Deaths and Disparities in a Longitudinal US Cohort.

abstract：Background:Vaccines have been used successfully for disease elimination programs in many countries. Evidence on the impact of vaccination programs can support decision-making among medical practitioners and policy makers to improve immunization rates. We estimated the health and economic impact of measles vaccination f...

journal_title：Open forum infectious diseases

authors： Paternina-Caicedo A,Driessen J,Roberts M,van Panhuis WG

更新日期：2018-06-16 00:00:00

abstract：Background:Maintaining retention in preexposure prophylaxis (PrEP) care among diverse patient populations will be needed to support PrEP's efficacy. We characterized patterns of PrEP care retention in a US municipal primary care health network and examined whether missed visits, a metric of care retention that is easy ...

journal_title：Open forum infectious diseases

authors： Spinelli MA,Scott HM,Vittinghoff E,Liu AY,Gonzalez R,Morehead-Gee A,Gandhi M,Buchbinder SP

更新日期：2019-02-26 00:00:00

abstract：BACKGROUND:Invasive aspergillosis (IA) and mucormycosis contribute to substantial mortality, especially among immunocompromised persons, including those with hematopoietic stem cell transplant (HSCT), hematologic malignancy (HM), and solid organ transplant (SOT). METHODS:Using International Classification of Diseases,...

journal_title：Open forum infectious diseases

authors： Vallabhaneni S,Benedict K,Derado G,Mody RK

更新日期：2017-01-13 00:00:00

abstract：:We present a case of a 20-year-old male who had ambiguous HIV test results after entering new provider care and whose status was later complicated by undetectable viral RNA off antiretroviral therapy (ART). Verifying HIV infection status may occasionally require sensitive DNA testing that might need to be considered i...

journal_title：Open forum infectious diseases

authors： Springer SA,Masciotra S,Johnson JA,Campbell S

更新日期：2020-10-10 00:00:00

abstract：Background:In human immunodeficiency virus (HIV) treatment, tenofovir alafenamide (TAF) is associated with greater increases in all fasting cholesterol subgroups compared with tenofovir disoproxil fumarate (TDF). Because lipid abnormalities may contribute to cardiovascular morbidity and mortality, cardiovascular risk a...

journal_title：Open forum infectious diseases

authors： Huhn GD,Shamblaw DJ,Baril JG,Hsue PY,Mills BL,Nguyen-Cleary T,McCallister S,Das M

更新日期：2019-11-11 00:00:00

abstract：BACKGROUND:Ombitasvir, paritaprevir with ritonavir, and dasabuvir (OBV/PTV/r ± DSV) ±ribavirin (RBV) are approved to treat hepatitis C virus (HCV) genotype 1 and 4 infection. Here, we investigate the safety and efficacy of OBV/PTV/r + DSV ±RBV for HCV genotype 1, and OBV/PTV/r + RBV for HCV genotype 4, in human immunod...

journal_title：Open forum infectious diseases

authors： Rockstroh JK,Orkin C,Viani RM,Wyles D,Luetkemeyer AF,Lazzarin A,Soto-Malave R,Nelson MR,Bhagani SR,Klinker HHF,Rizzardini G,Girard PM,Tural C,Shulman NS,Mobashery N,Hu YB,Fredrick LM,Pilot-Matias T,Trinh R,Gane E

更新日期：2017-07-22 00:00:00

abstract：Background:Cytomegalovirus (CMV) mononucleosis is a manifestation of primary CMV infection. This study aims to establish the link between long-term population CMV seroepidemiological trends and incidence of CMV mononucleosis requiring hospitalization. Furthermore, by analyzing serial laboratory data of patients hospita...

journal_title：Open forum infectious diseases

authors： Sridhar S,Chung TWH,Chan JFW,Cheng VCC,Lau SKP,Yuen KY,Woo PCY

更新日期：2018-10-20 00:00:00

abstract：Background:Cutaneous leishmaniasis (CL) caused by L. braziliensis is characterized by 1 or multiple well-limited ulcerated lesions. Diabetes mellitus (DM) impairs neutrophil and monocyte function, and there is a report of vegetative lesions in a patient with both diseases in Morocco. Here we evaluate the influence of D...

journal_title：Open forum infectious diseases

authors： Lago AS,Lima FR,Carvalho AM,Sampaio C,Lago N,Guimarães LH,Lago J,Machado PRL,Carvalho LP,Arruda S,Carvalho EM

更新日期：2020-10-19 00:00:00

abstract：:We assessed the impact of a rapid molecular assay for influenza detection whether outsourced or performed onsite 24/7 in a University Hospital in Paris, France. Shorter median time-to-results (16.8 vs 2.3 hours, P < .05) and an increased rate of adequate prescription of oseltamivir (76.6% vs 95.3%, P < .05) were obser...

journal_title：Open forum infectious diseases

authors： Jacquier H,Péan de Ponfilly G,Chauvin A,Amarsy R,Benmansour H,Hoang-Nguyen DT,Lecorché E,Mesnil C,Mougari F,Munier AL,Salmona M,Berçot B,Le Goff J,Cambau E

更新日期：2020-08-25 00:00:00

abstract：:Background.  Sepsis is a serious and common condition with high mortality and morbidity. The public awareness, knowledge, and perception of sepsis in Sweden are unknown. Methods.  A survey was performed using an online interview distributed to adults, aged 18-74, between March 6 and 9, 2015. Results.  A total of 1001 ...

journal_title：Open forum infectious diseases

authors： Mellhammar L,Christensson B,Linder A

更新日期：2015-10-26 00:00:00

abstract：:Peritoneal dialysis (PD)-associated peritonitis constitutes a major complication associated with the procedure. PD-associated peritonitis caused by nontuberculous mycobacteria, usually as a result of an infection related to the PD catheter, has been reported in adults and is associated with significant complications a...

journal_title：Open forum infectious diseases

authors： Imam O,Al-Zubaidi K,Janahi M,Imam A,Leghrouz B,Dobson S,Sundararaju S,Tsui KM,Hasan MR,Perez-Lopez A

更新日期：2020-11-27 00:00:00

abstract：:This article provides a comprehensive review of currently available treatment options for infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance in Gram-negative bacteria is an emerging and serious global public health threat. Carbapenems have been used as the "last-line" treatment f...

journal_title：Open forum infectious diseases

authors： Morrill HJ,Pogue JM,Kaye KS,LaPlante KL

更新日期：2015-05-05 00:00:00

abstract：:Passive surveillance data had signaled the possibility of gastrointestinal adverse events occurring after the administration of high-dose inactivated influenza vaccine (IIV-HD). However, in a large, prospective randomized clinical trial, rates of serious gastrointestinal events were no greater among IIV-HD recipients ...

journal_title：Open forum infectious diseases

authors： Talbot HK,Dunning AJ,Robertson CA,Landolfi VA,Greenberg DP,DiazGranados CA

更新日期：2018-05-22 00:00:00

abstract：Background:Clinical features of Lyme disease (LD) range from localized skin lesions to serious disseminated disease. Information on risk factors for Lyme arthritis, facial palsy, carditis, and meningitis is limited but could facilitate disease recognition and elucidate pathophysiology. Methods:Patients from high-incid...

journal_title：Open forum infectious diseases

authors： Kwit NA,Nelson CA,Max R,Mead PS

更新日期：2017-11-18 00:00:00

abstract：Background:The 13-valent pneumococcal conjugate vaccine (PCV13) and the 23-valent pneumococcal polysaccharide vaccine (PPSV23) were both recommended to adults aged ≥65 years. The study examines adults ≥65 years for risk of adverse events (AEs) requiring medical attention following vaccination with PCV13 as compared wit...

journal_title：Open forum infectious diseases

authors： Tseng HF,Sy LS,Qian L,Liu IA,Mercado C,Lewin B,Tartof SY,Nelson J,Jackson LA,Daley MF,Weintraub E,Klein NP,Belongia E,Liles EG,Jacobsen SJ

更新日期：2018-05-02 00:00:00

abstract：: Background.  The mechanism of virologic failure (VF) of lopinavir/ritonavir (LPV/r) monotherapy is not well understood. We assessed sequence changes in human immunodeficiency virus-1 reverse-transcriptase (RT) and protease (PR) regions. Methods. ...

journal_title：Open forum infectious diseases

authors： Vardhanabhuti S,Katzenstein D,Bartlett J,Kumarasamy N,Wallis CL

更新日期：2016-08-24 00:00:00

abstract：Background:Patients with suspected tuberculosis are often overtreated with antituberculosis drugs. We evaluated the diagnostic value of the focused assessment with sonography for HIV-associated tuberculosis (FASH) in rural Tanzania. Methods:In a prospective cohort study, the frequency of FASH signs was compared betwee...

journal_title：Open forum infectious diseases

authors： Ndege R,Weisser M,Elzi L,Diggelmann F,Bani F,Gingo W,Sikalengo G,Mapesi H,Mchomvu E,Kamwela L,Mnzava D,Battegay M,Reither K,Paris DH,Rohacek M

更新日期：2019-04-25 00:00:00

abstract：BACKGROUND:Intra-abdominal infections (IAI) constitute a common reason for hospitalization. However, there is lack of standardization in empiric management of (1) anaerobes, (2) enterococci, (3) fungi, and (4) multidrug-resistant organisms (MDRO). The recommendation is to institute empiric coverage for some of these or...

journal_title：Open forum infectious diseases

authors： Marcus G,Levy S,Salhab G,Mengesha B,Tzuman O,Shur S,Burke E,Mayeda RC,Cochavi L,Perluk I,Zaidenstein R,Lazarovitch T,Dadon M,Marchaim D

更新日期：2016-12-20 00:00:00

abstract：:In this study, we report a complete (clinical, radiological, and virological) sustained (1 year) response after nivolumab salvage therapy in a progressive multifocal leukoencephalopathy patient. Analyses of the cells infiltrate in a pretreatment brain biopsy suggest that parenchymal programmed cell death-L1+ macrophag...

journal_title：Open forum infectious diseases

authors： Audemard-Verger A,Gasnault J,Faisant M,Besse MC,Martin-Silva N,Berra M,Fournier L,Boutemy J,Maigne G,De Boysson H,Ruet A,Vabret A,Chapon F,Martin-Blondel G,Aouba A

更新日期：2019-09-30 00:00:00

abstract：Background:The number of invasive group A Streptococcus (iGAS) infections due to hitherto extremely rare type emm74 strains has increased in several Canadian provinces since late 2015. We hypothesized that the cases recorded in the different provinces are linked and caused by strains of an emm74 clone that recently eme...

journal_title：Open forum infectious diseases

authors： Teatero S,McGeer A,Tyrrell GJ,Hoang L,Smadi H,Domingo MC,Levett PN,Finkelstein M,Dewar K,Plevneshi A,Athey TBT,Gubbay JB,Mulvey MR,Martin I,Demczuk W,Fittipaldi N

更新日期：2018-04-20 00:00:00

abstract：BACKGROUND:Because hospitals in a region are connected via patient sharing, a norovirus outbreak in one hospital may spread to others. METHODS:We utilized our Regional Healthcare Ecosystem Analyst software to generate an agent-based model of all the acute care facilities in Orange County (OC), California and simulated...

journal_title：Open forum infectious diseases

authors： Bartsch SM,Huang SS,Wong KF,Avery TR,Lee BY

更新日期：2014-07-02 00:00:00

abstract：:Toxoplasma encephalitis is a well recognized complication of acquired immune deficiency syndrome, solid organ transplantation, and allogeneic hematopoietic stem cell transplantation (HSCT). However, patients with hematologic malignancies not treated with allogeneic HSCT may also develop this condition, which requires ...

journal_title：Open forum infectious diseases

authors： Morjaria S,Epstein DJ,Romero FA,Taur Y,Seo SK,Papanicolaou GA,Hatzoglou V,Rosenblum M,Perales MA,Scordo M,Kaltsas A

更新日期：2016-03-30 00:00:00

abstract：:Background.  Sepsis is a major cause of morbidity and mortality among older adults. The main goals of this study were to assess the association of sepsis at intensive care unit (ICU) admission with mortality and to identify predictors associated with increased mortality in older adults. Methods.  We conducted a prospe...

journal_title：Open forum infectious diseases

authors： Rowe T,Araujo KL,Van Ness PH,Pisani MA,Juthani-Mehta M

更新日期：2016-01-21 00:00:00

abstract：Background:Preventing severe complications of influenza such as hospitalization is a public health priority; however, estimates of influenza vaccine effectiveness (VE) against influenza-associated acute lower respiratory tract infection (LRTI) hospitalizations are limited. We examined influenza VE against influenza-ass...

journal_title：Open forum infectious diseases

authors： Chow EJ,Rolfes MA,Carrico RL,Furmanek S,Ramirez JA,Ferdinands JM,Fry AM,Patel MM

更新日期：2020-06-30 00:00:00

abstract：:Background.  Advanced fibrosis occurs more commonly in human immunodeficiency virus (HIV)-hepatitis B virus (HBV) coinfected individuals; therefore, fibrosis monitoring is important in this population. However, transient elastography (TE) data in HIV-HBV coinfection are lacking. We aimed to assess liver fibrosis using...

journal_title：Open forum infectious diseases

authors： Audsley J,Robson C,Aitchison S,Matthews GV,Iser D,Sasadeusz J,Lewin SR

更新日期：2016-02-12 00:00:00

abstract：Background:Patients with chronic hepatitis C virus (HCV) infection and active or previous hepatitis B virus (HBV) are at risk of HBV reactivation (HBV-R) during direct-acting antiviral (DAA) therapy. Recent reports suggest that HBV-R may even occur several months after completion of DAA therapy. The aim of this study w...

journal_title：Open forum infectious diseases

authors： Mücke MM,Mücke VT,Peiffer KH,Sarrazin C,Zeuzem S,Berger A,Vermehren J

更新日期：2018-12-15 00:00:00

abstract：Background:In 2012, the US Food and Drug Administration (FDA) required drug manufacturers to give advance notice of impending drug shortages. A survey of infectious diseases (ID) physicians was undertaken to determine the impact of this requirement and to follow-up on prior perceptions of ID physicians on shortages of ...

journal_title：Open forum infectious diseases

authors： Gundlapalli AV,Beekmann SE,Graham DR,Polgreen PM,Members of the Emerging Infections Network.

更新日期：2018-04-23 00:00:00

abstract：Background:US hematopoietic cell transplantation (HCT) recipients have a low prevalence of latent tuberculosis infection (LTBI), but if latently infected they are at risk for progression to active tuberculosis. At our center, all HCT recipients underwent LTBI testing pretransplant by tuberculin skin testing (TST) until...

journal_title：Open forum infectious diseases

authors： Sosa-Moreno A,Narita M,Spitters C,Swetky M,Podczervinski S,Lind ML,Holmberg L,Liu C,Edelstein R,Pergam SA

更新日期：2020-06-10 00:00:00

abstract：:We investigated the microbial burden on the operating room environment when patients on contact precautions for a multidrug-resistant pathogen received surgery. Our study demonstrated that the perioperative environment was contaminated with aerobic bacteria and methicillin-resistant Staphylococcus aureus (MRSA) after ...

journal_title：Open forum infectious diseases

authors： Kanamori H,Rutala WA,Gergen MF,Weber DJ

更新日期：2020-10-27 00:00:00

abstract：Background:Kindergarten-entry vaccination requirements have played an important role in controlling vaccine-preventable diseases in the United States. Forty-eight states and the District of Colombia offer nonmedical exemptions to vaccines, ranging in stringency. Methods:We analyzed state-level exemption data from 2011...

journal_title：Open forum infectious diseases

authors： Omer SB,Porter RM,Allen K,Salmon DA,Bednarczyk RA

更新日期：2017-11-15 00:00:00