Retracted: miR-26a-5p Regulates Synovial Fibroblast Invasion in Patients with Rheumatoid Arthritis by Targeting Smad.

abstract：:BACKGROUND Different blood pressure targets should be formulated for different groups of people. This study aimed to assess the effectiveness of intensive blood control in improving the carotid morphology and hemodynamics in Chinese patients with hyperhomocysteinemia-type hypertension and high risk of stroke. MATERIAL...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wu W,Liu J,Li A,Li J,Yang Y,Ye X,Zheng J

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Dysfunction of blood vessels and endothelial cells is regarded as a primary triggering factor of the development of autoimmunological processes in systemic sclerosis (scleroderma, SSc). Literature data suggest that the duration of Raynaud's phenomenon may correlate with disease severity. MATERIAL/METHODS:Th...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dziankowska-Bartkowiak B,Zalewska A,Sysa-Jedrzejowska A

更新日期：2004-05-01 00:00:00

abstract：:BACKGROUND At present, whether human cytomegalovirus (HCMV) infection is associated with type 2 diabetes mellitus (T2DM) is debatable. The effect of active HCMV infection on glucose regulation has been poorly studied. Although HCMV infection is correlated with atherosclerosis in cardiovascular disease, the role of HCM...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang J,Liu YY,Sun HL,Li S,Xiong HR,Yang ZQ,Xiang GD,Jiang XJ

更新日期：2015-12-30 00:00:00

abstract：:The most prominent theory describes the Crohn's Syndrome as a dysregulated, inappropriate immune response to otherwise innocuous bowel flora in a genetically susceptible host. The autoimmune theory assumes that a specific infectious agent does not exist. Data from mouse models, impairment of the mucosal epithelial bar...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chamberlin WM,Naser SA

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Aortic cross-clamping during abdominal aortic aneurysm (AAA) open repair leads to development of ischemia-reperfusion injury. Electron paramagnetic resonance spectroscopy (EPR) spin-trapping is a valuable method of direct measurement of free radicals. The objective of the study was to evaluate the results of...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Majewski W,Krzyminiewski R,Stanisić M,Iskra M,Krasiński Z,Nowak M,Dobosz B

更新日期：2014-11-27 00:00:00

abstract：BACKGROUND:Detection of Leishmania parasite in patients by classical methods at the early stage of infection is limited. Several studies have shown that polymerase chain reaction (PCR) is more effective for the diagnosis of visceral Leishmaniasis (VL) in clinical samples. The purpose of this study was to develop a simp...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Pal S,Aggarwal G,Haldar A,Majumdar A,Majumdar HK,Duttagupta S

更新日期：2004-01-01 00:00:00

abstract：:BACKGROUND The purpose of the present study was to investigate the function and mechanism of dihydroartemisinin (DHA) in treating ovalbumin-induced asthma in BALB/c mice. MATERIAL AND METHODS Thirty female BALB/c mice were randomly separated into 3 groups: the control group, the asthma model group stimulated by ovalbu...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu H,Ji W

更新日期：2019-05-22 00:00:00

abstract：BACKGROUND:Despite the wide application of open reduction and internal fixation with locking plates for the treatment of proximal humeral fractures, the surgical invasive approach remains controversial. This study aimed to evaluate the pros and cons of the minimally invasive lateral approach for the treatment of proxim...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu K,Liu PC,Liu R,Wu X

更新日期：2015-02-15 00:00:00

abstract：:BACKGROUND Colorectal cancer (CRC) has become a heavy health burden around the world, accounting for about 10% of newly diagnosed cancer cases. In the present study, we aimed to establish the miRNA-based prediction signature to assess the prognosis of CRC patients. MATERIAL AND METHODS A total of 451 CRC patients' exp...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Qian J,Zeng L,Jiang X,Zhang Z,Luo X

更新日期：2019-09-27 00:00:00

abstract：:BACKGROUND Endothelial injury is the main mechanism of atherosclerosis, and is caused by oxidized low-density lipoprotein (ox-LDL). Astragaloside IV (AS-IV) is the primary active ingredient of the Chinese herb Huangqi, and exhibits antioxidant and anti-inflammatory properties in cardiovascular diseases. This study inv...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu Z,Li J,Zhang X

更新日期：2019-03-22 00:00:00

abstract：BACKGROUND:The aim of this study was to analyze the effects of obesity and leptin levels on patients with migraine, and to observe the change of leptin levels in migraineurs. MATERIAL AND METHODS:We enrolled 52 migraine patients from the Headache Clinic in Shandong Provincial Hospital into a randomized controlled tria...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ligong Z,Jinjin Q,Chunfu C,Congcong L,Xiaojun D

更新日期：2015-10-28 00:00:00

abstract：:BACKGROUND Splenic injury is the leading cause of major bleeding after blunt abdominal trauma. We examined the clinical and radiological presentations, management, and outcome of blunt splenic injuries (BSI) in our institution. MATERIAL AND METHODS A retrospective study of BSI patients between 2011 and 2014 was conduc...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jabbour G,Al-Hassani A,El-Menyar A,Abdelrahman H,Peralta R,Ellabib M,Al-Jogol H,Asim M,Al-Thani H

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:Suicide gene therapy, particularly that utilizing the cytosine deaminase/5-fluorocytosine (CD/5-FC) system, represents a novel and attractive methodology of cancer research. Mechanistically, the CD enzyme can convert the antifungal agent 5-FC into the antimetabolite agent 5-fluorouracil (5-FU), thereby killi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lv SQ,Zhang KB,Zhang EE,Gao FY,Yin CL,Huang CJ,He JQ,Yang H

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The present study was carried out to compile normative data for dimensions of the common iliac arteries at varying gestational ages. MATERIAL/METHODS:We used anatomical dissection, digital-image analysis (system of Leica QWin Pro 16) and statistical analysis (Student T test, one-way ANOVA, post-hoc RIR Tuke...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Szpinda M,Szpinda A,Woźniak A,Daroszewski M,Mila-Kierzenkowska C

更新日期：2012-03-01 00:00:00

abstract：:BACKGROUND The present research aimed to explore the risk factors for adverse cardiovascular events in elderly patients with acute myocardial infarction (AMI) combined with NAFLD. MATERIAL AND METHODS We included 325 AMI patients hospitalized in the Department of Cardiology. AMI patients underwent emergency thrombolys...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xia W,Yang N,Li Y

更新日期：2020-06-01 00:00:00

abstract：:BACKGROUND Growing evidence indicates that a non-coding RNA named miR-34b/c plays crucial roles in carcinogenesis, and its common polymorphism, pri-miR-34b/c rs4938723, also participates in this process and is associated with cancer susceptibility. However, this association was previously undefined and ambiguous. Ther...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xu B,Zhu Y,Tang Y,Zhang Z,Wen Q

更新日期：2018-10-04 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is the main histologic form of lung cancer that affects human health, but biomarkers for therapeutic diagnosis and prognosis of the disease are currently lacking. The gene expression profile GSE18842 was downloaded from the Gene Expression Omnibus database in this prospective study, ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu X,Liu X,Li J,Ren F

更新日期：2019-12-05 00:00:00

abstract：:BACKGROUND More and more patients with lung adenocarcinoma were detected with ground glass nodule (GGN) due to the popularity of low-dose spiral computed tomography (LDCT) recently. The clinicopathological characteristics and epidermal growth factor receptor (EGFR) mutation features were unclear. MATERIAL AND METHODS ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xu Y,Zheng M,Wang N,Wang R

更新日期：2019-11-11 00:00:00

abstract：BACKGROUND:Factor XIII deficiency is a rare inherited bleeding disorder that is often difficult to diagnose. As there are no standard screening tests established patients with Factor XIII deficiency are not correctly identified. Especially postoperative bleeding and haemorrhage after difficult plastic reconstructive op...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Dragu A,Bach AD,Leffler M,Unglaub F,Horch RE

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Focal adhesion kinase (FAK) is an enzyme of the tyrosine kinase group linked to signaling pathways between cells and the extracellular matrix. In tumor cells in vitro, FAK expression correlated with their ability for invasion and metastasis. Additionally, in vivo FAK has been implicated in malignant transfor...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Theocharis SE,Klijanienko JT,Padoy E,Athanassiou S,Sastre-Garau XX

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Retinoblastoma (Rb) is the most common primary malignant intraocular tumour in childhood. The "two hit" theory, formulated by Knudson in 1971 to explain the variegated clinical expression of the disease, led to the discovery of the so called tumour suppressor genes and the identification of the Rb1 as the pr...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Mastrangelo D,De Francesco S,Di Leonardo A,Lentini L,Hadjistilianou T

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Serum CA-125 has been used as a biomarker of gynecological tumors. In this study, we investigated the CA-125 levels in cervical and vaginal secretions from Chinese patients with endometrial polyps, hyperplasia and carcinoma in comparison with those in endometrium and serum. MATERIAL/METHODS:An electro-chemi...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： He SM,Xing F,Sui H,Wu Y,Wang Y,Wang D,Chen G,Kong Z,Zhou SF

更新日期：2011-11-01 00:00:00

abstract：:BACKGROUND Stroke is a serious health problem all over the world. Ischemia causes 85% of strokes and 75% of these ischemic strokes occur within the area supplied by the internal carotid artery (ICA). MATERIAL AND METHODS This study included 47 acute stroke patients who were in the large-artery atherosclerosis group ac...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Alagoz AN,Acar BA,Acar T,Karacan A,Demiryürek BE

更新日期：2016-12-16 00:00:00

abstract：:BACKGROUND The aim of this study was to investigate the correlation between indocyanine green plasma disappearance rate (ICG-PDR) and allograft function as well as postoperative complications after liver transplantation. MATERIAL AND METHODS In this prospective study, 115 cases of adult liver transplantation performed...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Sun Y,Yu L,Liu Y

更新日期：2018-06-01 00:00:00

abstract：:Systemic diseases of connective tissue, including chronic juvenile arthritis are associated with a number of metabolic disorders such as e.g. lipid disturbances. The purpose of the present work was to analyse the composition of fatty acids in erythrocyte phospholipids of children with juvenile chronic arthritis and to...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Górska A,Nawrocki A,Urban M,Florys B

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Usefulness of anthropometric indices (AI) as predictors of CV risk is unclear and remains controversial. MATERIAL/METHODS:To evaluate the correlation between AI and CV risk factors in the Croatian adult population and to observe possible differences between coastal and inland regions and urban and rural set...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Vrdoljak D,Bergman Marković B,Kranjčević K,Ivezić Lalić D,Vučak J,Katić M

更新日期：2012-02-01 00:00:00

abstract：:BACKGROUND The aim of this study was to evaluate the effect of oral contraceptive pills (OCP) on the macula, the retinal nerve fiber layer (RNFL), and choroidal thickness (CT). MATERIAL AND METHODS A total of 24 healthy women taking monophasic OCP (3 mg drospirenone and 0.03 mg ethinylestradiol) for contraception only...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Madendag Y,Acmaz G,Atas M,Sahin E,Tayyar AT,Madendag IÇ,Özdemir F,Senol V

更新日期：2017-11-27 00:00:00

abstract：:BACKGROUND This study analyzed the macular 3D-OCT images of Vogt-Koyanagi-Harada disease (VKH) in uveitis, explored the characteristics of 3D-OCT images of the macular region of VKH, and assessed which characteristics contribute most to VKH diagnosis. MATERIAL AND METHODS The 3D-OCT examination of 25 cases of VKH was ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhao GL,Li RZ,Pang YH,Wang XQ,Peng HJ,Wei JF,Zhou Z

更新日期：2018-02-03 00:00:00

abstract：BACKGROUND:Benzodiazepine binding sites distinct from the GABA-receptor-chloride-complex in the central nervous system have been recognized in many peripheral tissues, but their physiological role remains unexplained. Our study was undertaken to examine the effects of diazepam, clonazepam, and PK 11195, a peripheral be...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Rajtar G,Zółkowska D,Kleinrok Z

更新日期：2002-04-01 00:00:00

abstract：:BACKGROUND The aim of this study was to explore the regulating effects of Substance P (SP) on the collagen synthesis of rat myocardial fibroblasts (CFBs) induced by angiotensin II (Ang II) and its potential mechanism. MATERIAL AND METHODS The CFBs of a neonatal SD rat were separately cultured and divided into the cont...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yang Z,Zhang X,Guo N,Li B,Zhao S

更新日期：2016-12-16 00:00:00