Dihydroartemisinin Ameliorated Ovalbumin-Induced Asthma in Mice via Regulation of MiR-183C.

abstract：:BACKGROUND Esophageal squamous cell carcinoma (ESCC), a major histological subtype of esophageal cancer, is a common cause of tumor-related deaths in the world. Due to the lack of understanding of the pathogenesis of ESCC, its clinical treatment is still a big challenge. In the present study, we aimed to identify an E...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang X,Gu M,Ju Y,Zhou J

更新日期：2020-03-24 00:00:00

abstract：:BACKGROUND Effective early management of cerebral infarction patients with transient ischemic attack (TIA) is undermined by an inability to predict who is at highest risk of stroke. MATERIAL AND METHODS A total of 577 TIA patients with symptoms lasting no more than 1 hour were prospectively investigated and divided in...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Lu Y,Yu J,Hu J,Tan Y,Wu J,Zhao Y,Liu X

更新日期：2019-01-02 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the influence of genetic polymorphism of cholesteryl ester transfer protein (CETP) gene polymorphism -629C/A on the therapeutic effect of atorvastatin and clinical outcome in Han Chinese patients with coronary heart disease (CHD). MATERIAL AND METHODS:From October 20...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Gu GL,Xu XL,Yang QY,Zeng RL

更新日期：2014-12-30 00:00:00

abstract：BACKGROUND:Inflammation and pulmonary injury caused by mechanical ventilation is a complex process in which long pentraxin 3 (PTX3) is suggested to play an important role. The effect of mechanical stretch on PTX3 mRNA and protein expression in human alveolar epithelial cells (A549) was investigated. MATERIAL/METHODS:I...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wu Q,Shu H,Yao S,Xiang H

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Cajal bodies (CB) are distinct sub-nuclear domains rich in small nuclear ribonucleoprotein particles (snRNPs); they are involved in pre-mRNA processing. Lupus erythematosus (SLE) is an autoimmune disease characterized by autoantibody production against different nuclear molecules, including those involved in...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Vázquez-Talavera J,Ramírez-Sandoval R,Esparza Ibarra E,Avalos-Díaz E,Herrera-Esparza R

更新日期：2004-05-01 00:00:00

abstract：UNLABELLED:BACKGROUND; Cerebral amyloid angiopathy (CAA) is a condition characterized by amyloid deposition in the walls of leptomeningal and cerebral cortical blood vessels. Clinically, CAA results in recurrent lobar haemorrhage that frequently presents with cognitive impairment or recurrent cerebral ischaemic events....

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Felwick R,Amar K

更新日期：2007-02-01 00:00:00

abstract：:BACKGROUND Septin9 is a member of GTP-binding protein family, and is used as a predictive diagnostic index. However, it has not been widely adopted due to inconsistent results reported in the literature. The present study was performed to determine the diagnostic accuracy of methylated Septin9 (mSEPT9) for colorectal ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yan S,Liu Z,Yu S,Bao Y

更新日期：2016-09-25 00:00:00

abstract：BACKGROUND:Semipermeability to fluid transport is one of the principal attributes of a tissue like articular cartilage. Consequently, this characteristic can be exploited in attempts to understand the functional roles of the biological layer of Surface Active Phospholipids (SAPL) which form on its surfaces. A previous ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Y,Crawford RW,Oloyede A

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The associations between the thrombomodulin (TM) polymorphisms and coronary artery disease (CAD) risk remain controversial. The aim of this study was to evaluate the association of TM polymorphisms with CAD susceptibility using a meta-analysis approach. MATERIAL/METHODS:All eligible studies were identified ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang S,Zhang Z,Zhang F,Wei C,Bu Y,Zheng S,Su D

更新日期：2014-08-10 00:00:00

abstract：:BACKGROUND Recent studies have suggested that hepatocyte senescence could contribute to hepatic steatosis and its progression in nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanism causing hepatocyte senescence in this pathological condition is still unclear. A thorough understanding of the mec...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang J,Li Y,Wang B,Luo Y,Shi J,Zhao B

更新日期：2020-03-19 00:00:00

abstract：:BACKGROUND Serum hepatitis B virus (HBV) DNA and hepatitis B e antigen (HBeAg) liver function in patients with chronic hepatitis B (CHB) are significantly associated. A comparison of clinical significance of fecal HBV DNA and serum HBV DNA has not yet been reported. MATERIAL AND METHODS Stool and serum samples were co...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zheng JS,Chen MM,Yang HF,Zhou XT,Liu YY,Li JB

更新日期：2015-12-09 00:00:00

abstract：:BACKGROUND Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) aggravates the overall severity in COPD patients, resulting in severe morbidity and mortality. However, there are no objective biomarkers currently available to predict the development of AECOPD. Several studies have indicated that galecti...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Feng W,Wu X,Li S,Zhai C,Wang J,Shi W,Li M

更新日期：2017-09-26 00:00:00

abstract：:BACKGROUND To investigate the prognostic value of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), and pancreatic stone protein (PSP) in children with sepsis. MATERIAL AND METHODS A total of 214 patients with sepsis during hospitalization were enrolled. Serum levels of PCT, hs-CRP, and PSP were measu...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wu Q,Nie J,Wu FX,Zou XL,Chen FY

更新日期：2017-03-30 00:00:00

abstract：:BACKGROUND The aim of this study was to discuss the possible roles and clinical value of 2 circRNAs (hsa_circ_0049224 and has_circ_0049220) in SLE patients. MATERIAL AND METHODS Reverse-transcription real-time polymerase chain reaction (RT-PCR) was conducted to detect the expressions of hsa_circ_0049224, has_circ_0049...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang C,Huang J,Chen Y,Shi W

更新日期：2018-04-02 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase-2 (MMP-2) has been shown to activate a non-thromboxane, non-ADP pathway of platelet aggregation. In contrast, nitric oxide (NO) is known to inhibit platelet adhesion and aggregation. Therefore, we have studied the release of MMP-2 during platelet adhesion to fibrinogen, the effects o...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Martinez A,Salas E,Radomski A,Radomski MW

更新日期：2001-07-01 00:00:00

abstract：:BACKGROUND In recent years, emerging evidence has suggested that ulcerative colitis occurs as a consequence of an imbalance between oxidative stress and antioxidant capacity. The objective of this study was to investigate whether serum total bilirubin and serum uric acid levels were associated with ulcerative colitis....

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tian S,Li J,Li R,Liu Z,Dong W

更新日期：2018-09-09 00:00:00

abstract：BACKGROUND:Leptin plays an important role in controlling satiety and maintaining energy balance. Acromegaly is characterized by decreased fat, which increases after the disease is cured. Our objective was to investigate serum leptin in acromegaly in terms of disease activity, body fat content, insulin and glucose level...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bolanowski M,Milewicz A,Bidzińska B,Jedrzejuk D,Daroszewski J,Mikulski E

更新日期：2002-10-01 00:00:00

abstract：:BACKGROUND A prospective clinical study was conducted to assess different regimens of steroid therapy and preservation of hearing following cochlear implantation. MATERIAL AND METHODS Study participants were ≥18 years-of-age, with a cochlear duct length ≥27.1 mm measured by computed tomography (CT), with hearing sound...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Skarżyńska MB,Skarżyński PH,Król B,Kozieł M,Osińska K,Gos E,Skarżyński H

更新日期：2018-04-22 00:00:00

abstract：:Selective COX-2 inhibitors increase the risk of myocardial infarction and stroke that is attributed to their ability to inhibit prostacyclin (PGI2), lipoxins, resolvins, and endothelial nitric oxide (eNO) but not platelet COX-1 derived thromboxane A2 (TXA2). In contrast, aspirin blocks both COX-1 and COX-2 enzymes tha...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Das UN

更新日期：2005-07-01 00:00:00

abstract：:The purpose of this study was to investigate the distribution of Chlamydia trachomatis (CT) genotypes in infective diseases of the female lower genital tract, especially in cervical diseases. This study included 128 CT-positive women. DNA was extracted from cervical swabs. Omp1 gene PCR-RFLP and sequencing were used t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Y,Chen J,Yang L,Jiang Y,Li L,Yi W,Lan L,Zhang L

更新日期：2017-09-17 00:00:00

abstract：BACKGROUND:The study aimed at evaluating neopterin concentration in relation to heart failure etiology and determining basal neopterin concentration in relation to the clinical state of patients after 12 months of standard treatment. MATERIAL/METHODS:The examined group was composed of 47 patients with NYHA class II an...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wietlicka-Kokoszanek I,Jablecka A,Smolarek I,Bogdanski P,Chmara E,Korzeniowska K,Kazmierczak M,Kazmierczak E,Musialik K

更新日期：2010-05-01 00:00:00

abstract：:BACKGROUND The prevalence of chronic pain among the elderly is high (estimated at 25-85%) and may adversely affect their everyday functioning, although it is often unrecognized. MATERIAL AND METHODS The aim of this study was to assess the prevalence of chronic pain, especially with th...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Stompór M,Grodzicki T,Stompór T,Wordliczek J,Dubiel M,Kurowska I

更新日期：2019-04-12 00:00:00

abstract：:BACKGROUND Protein kinase C zeta (PKC ζ) plays an important role in insulin induced glycometabolism and insulin receptor (IR) associated signaling pathways. The full activation of PKC ζ depends on its translocation from cytosol to membrane and phosphorylation at Thr410. However, the mechanism of PKC ζ activation remai...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yingying X,Caijuan W,Yenan Y,Yuqin T,Xueqin C,Zhongming W

更新日期：2017-07-28 00:00:00

abstract：:BACKGROUND At present, whether human cytomegalovirus (HCMV) infection is associated with type 2 diabetes mellitus (T2DM) is debatable. The effect of active HCMV infection on glucose regulation has been poorly studied. Although HCMV infection is correlated with atherosclerosis in cardiovascular disease, the role of HCM...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhang J,Liu YY,Sun HL,Li S,Xiong HR,Yang ZQ,Xiang GD,Jiang XJ

更新日期：2015-12-30 00:00:00

abstract：:BACKGROUND The aim of this study was to investigate the clinical significance of NLRP3 and HMGB1 in patients with active ulcerative colitis. MATERIAL AND METHODS This was a prospective observational study which included a total of 62 cases with active ulcerative colitis during January 2017 to December 2018. The patien...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chen Y,Wu D,Sun L

更新日期：2020-01-05 00:00:00

abstract：BACKGROUND:Transforming growth factor-β1 is a member of a large class of polypeptides that regulate the proliferation, differentiation, and carcinogenesis of epithelial cells. The rs1800470 polymorphism influences transforming growth factor-β1 expression and has been associated with lung cancer susceptibility. However,...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Fan H,Yu H,Deng H,Chen X

更新日期：2014-11-20 00:00:00

abstract：:BACKGROUND Osteoporosis is a common disorder leading to bone loss. At present, the treatment options available for the management of osteoporosis are limited. The present investigation evaluated the protective effect of fangchinoline against osteoporosis and also postulates the possible mechanism of action. MATERIAL A...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu W,Ding W,Shang X,Zhu D,Dai X

更新日期：2019-01-11 00:00:00

abstract：:BACKGROUND Colorectal carcinoma (CRC) is one of the most frequently diagnosed malignancies. Cucurbitacin B (CuB) is a natural compound isolated from herbs and shows anticancer activity in several cancers. MATERIAL AND METHODS Here, we analyzed the effects of different CuB concentrations on the proliferative and invasive...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chai Y,Xiang K,Wu Y,Zhang T,Liu Y,Liu X,Zhen W,Si Y

更新日期：2018-12-19 00:00:00

abstract：BACKGROUND:Changing a central venous catheter occlusive dressing on a twice-weekly basis is usually recommended in hemato-oncological patients. A longer interval is believed to give rise to infections. However, frequent dressing changes might cause local cutaneous damage. MATERIAL/METHODS:Local cutaneous damage and in...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Vokurka S,Bystricka E,Visokaiova M,Scudlova J

更新日期：2009-03-01 00:00:00

abstract：:BACKGROUND Hepatocellular carcinoma (HCC) is one of the most common malignancies occurring worldwide and is most frequent type of liver cancer. The risk for developing HCC increases with the severity of inflammation and fibrosis. The members of the interleukin-1 (IL-1) family are primarily proinflammatory cytokines du...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Tak KH,Yu GI,Lee MY,Shin DH

更新日期：2018-05-26 00:00:00