Group-based developmental BMI trajectories, polycystic ovary syndrome, and gestational diabetes: a community-based longitudinal study.

abstract：:Proteinuria is a defining criterion for the diagnosis of pre-eclampsia. The amount of protein lost per day has been thought by some to predict both maternal and fetal outcome. The systematic review of 16 primary papers including over 6700 patients by Thangaratinam and colleagues published this month in BMC Medicine su...

journal_title：BMC medicine

authors： Hofmeyr GJ,Belfort M

更新日期：2009-03-24 00:00:00

abstract：BACKGROUND:Accurate and timely cause of death (COD) data are essential for informed public health policymaking. Medical certification of COD generally provides the majority of COD data in a population and is an essential component of civil registration and vital statistics (CRVS) systems. Accurate completion of the med...

journal_title：BMC medicine

authors： Hart JD,Sorchik R,Bo KS,Chowdhury HR,Gamage S,Joshi R,Kwa V,Li H,Mahesh BPK,Mclaughlin D,Mikkelsen L,Miki J,Napulan R,Rampatige R,Reeve M,Sarmiento C,War NS,Richards N,Riley ID,Lopez AD

更新日期：2020-03-09 00:00:00

abstract：BACKGROUND:Insulin-like growth factor-1 (IGF-I) signalling is important for cancer initiation and progression. Given the emerging evidence for the role of the stroma in these processes, we aimed to characterize the effects of IGF-I on cancer cells and stromal cells separately. METHODS:We used an ex vivo culture model ...

journal_title：BMC medicine

authors： Rajski M,Zanetti-Dällenbach R,Vogel B,Herrmann R,Rochlitz C,Buess M

更新日期：2010-01-05 00:00:00

abstract：BACKGROUND:Adiposity is a strong risk factor for cancer incidence and mortality. However, most of the evidence available has focused on body mass index (BMI) as a marker of adiposity. There is limited evidence on relationships of cancer with other adiposity markers, and if these associations are linear or not. The aim ...

journal_title：BMC medicine

authors： Parra-Soto S,Cowley ES,Rezende LFM,Ferreccio C,Mathers JC,Pell JP,Ho FK,Celis-Morales C

更新日期：2021-01-11 00:00:00

abstract：BACKGROUND:Tumor necrosis factor (TNF)-α inhibitors are increasingly being used in inflammatory bowel disease (IBD). Because this chronic intestinal disorder often affects women of fertile age, it is essential to assess the effect of biologics on pregnancy outcome. METHODS:We performed a systematic review of the Engli...

journal_title：BMC medicine

authors： Nielsen OH,Loftus EV Jr,Jess T

更新日期：2013-07-31 00:00:00

abstract：BACKGROUND:Lethal and edema toxins secreted by Bacillus anthracis during anthrax infection were found to incite serious cardiovascular complications. However, the underlying mechanisms in anthrax lethal toxin-induced cardiac anomalies remain unknown. This study was designed to evaluate the impact of antioxidant enzyme ...

journal_title：BMC medicine

authors： Kandadi MR,Yu X,Frankel AE,Ren J

更新日期：2012-11-07 00:00:00

abstract：BACKGROUND:Niemann-Pick disease type C is a fatal and progressive neurodegenerative disorder characterized by the accumulation of unesterified cholesterol in late endosomes and lysosomes. We sought to develop new therapeutics for this disorder by harnessing the body's endogenous cholesterol scavenging particle, high-de...

journal_title：BMC medicine

authors： Schultz ML,Fawaz MV,Azaria RD,Hollon TC,Liu EA,Kunkel TJ,Halseth TA,Krus KL,Ming R,Morin EE,McLoughlin HS,Bushart DD,Paulson HL,Shakkottai VG,Orringer DA,Schwendeman AS,Lieberman AP

更新日期：2019-11-11 00:00:00

abstract：BACKGROUND:Dietary assessment is complex, and strategies to select the most appropriate dietary assessment tool (DAT) in epidemiological research are needed. The DIETary Assessment Tool NETwork (DIET@NET) aimed to establish expert consensus on Best Practice Guidelines (BPGs) for dietary assessment using self-report. M...

journal_title：BMC medicine

authors： Cade JE,Warthon-Medina M,Albar S,Alwan NA,Ness A,Roe M,Wark PA,Greathead K,Burley VJ,Finglas P,Johnson L,Page P,Roberts K,Steer T,Hooson J,Greenwood DC,Robinson S,DIET@NET consortium.

更新日期：2017-11-15 00:00:00

abstract：BACKGROUND:Human fetal adrenal glands are highly active and, with the placenta, regulate circulating progesterone, estrogen and corticosteroids in the fetus. At birth the adrenals are essential for neonate salt retention through secretion of aldosterone, while adequate glucocorticoids are required to prevent adrenal in...

journal_title：BMC medicine

authors： Johnston ZC,Bellingham M,Filis P,Soffientini U,Hough D,Bhattacharya S,Simard M,Hammond GL,King P,O'Shaughnessy PJ,Fowler PA

更新日期：2018-02-12 00:00:00

abstract：BACKGROUND:Atrazine (2-chloro-4-ethytlamino-6-isopropylamine-1,3,5-triazine; ATR), is the most commonly applied broad-spectrum herbicide in the world. Unintentional overspray of ATR poses an immune function health hazard. The biomolecular mechanisms responsible for ATR-induced immunotoxicity, however, are little unders...

journal_title：BMC medicine

authors： Zhang X,Wang M,Gao S,Ren R,Zheng J,Zhang Y

更新日期：2011-10-27 00:00:00

abstract：:Although imatinib is firmly established as an effective therapy for newly diagnosed patients with chronic myeloid leukemia (CML), the field continues to advance on several fronts. In this minireview we cover recent results of second generation tyrosine kinase inhibitors in newly diagnosed patients, investigate the sta...

journal_title：BMC medicine

authors： Eiring AM,Khorashad JS,Morley K,Deininger MW

更新日期：2011-08-26 00:00:00

abstract：BACKGROUND:The World Health Organisation estimates that by 2030 there will be approximately 350 million people with type 2 diabetes. Associated with renal complications, heart disease, stroke and peripheral vascular disease, early identification of patients with undiagnosed type 2 diabetes or those at an increased risk...

journal_title：BMC medicine

authors： Collins GS,Mallett S,Omar O,Yu LM

更新日期：2011-09-08 00:00:00

abstract：BACKGROUND:In July 2014, an outbreak of Ebola virus disease (EVD) started in Pujehun district, Sierra Leone. On January 10th, 2015, the district was the first to be declared Ebola-free by local authorities after 49 cases and a case fatality rate of 85.7%. The Pujehun outbreak represents a precious opportunity for impro...

journal_title：BMC medicine

authors： Ajelli M,Parlamento S,Bome D,Kebbi A,Atzori A,Frasson C,Putoto G,Carraro D,Merler S

更新日期：2015-11-26 00:00:00

abstract：:Severe anemia contributes significantly to child mortality in sub-Saharan Africa. Blood transfusion is used in emergencies but carries risks. In BMC Medicine, Olupot-Olupot and colleagues report the findings of a phase II trial in children with severe anemia in Eastern Uganda. They provide important early safety and e...

journal_title：BMC medicine

authors： Brick T,Peters MJ

更新日期：2014-04-25 00:00:00

abstract：BACKGROUND:Recently, some US cohorts have shown a moderate association between red and processed meat consumption and mortality supporting the results of previous studies among vegetarians. The aim of this study was to examine the association of red meat, processed meat, and poultry consumption with the risk of early d...

journal_title：BMC medicine

authors： Rohrmann S,Overvad K,Bueno-de-Mesquita HB,Jakobsen MU,Egeberg R,Tjønneland A,Nailler L,Boutron-Ruault MC,Clavel-Chapelon F,Krogh V,Palli D,Panico S,Tumino R,Ricceri F,Bergmann MM,Boeing H,Li K,Kaaks R,Khaw KT,Wareha

更新日期：2013-03-07 00:00:00

abstract：BACKGROUND:There has been concern that the incidence of autism and other pervasive developmental disorders (PDDs) is increasing. Previous studies have been smaller, restricted to autism (excluding other pervasive developmental disorders such as Asperger's syndrome), included boys only, or have not been based on a natio...

journal_title：BMC medicine

authors： Smeeth L,Cook C,Fombonne PE,Heavey L,Rodrigues LC,Smith PG,Hall AJ

更新日期：2004-11-09 00:00:00

abstract：BACKGROUND:Despite the worldwide increasing burden of diabetes, there has been no corresponding scale-up of treatment in developing countries and limited evidence of program effectiveness. In 2002, in collaboration with the Ministry of Health of Cambodia, Médecins Sans Frontières initiated an outpatient program of subs...

journal_title：BMC medicine

authors： Raguenaud ME,Isaakidis P,Reid T,Chy S,Keuky L,Arellano G,Van Damme W

更新日期：2009-07-14 00:00:00

abstract：BACKGROUND:The cost-effectiveness of universal rotavirus (RV) vaccination is controversial in developed countries. As a result, RV vaccination programs do not currently exist in most European countries. Hospitalization is the main driver of RV disease costs, and prematurity, low birth weight (LBW) and underlying medica...

journal_title：BMC medicine

authors： Bruijning-Verhagen P,Mangen MJ,Felderhof M,Hartwig NG,van Houten M,Winkel L,de Waal WJ,Bonten MJ

更新日期：2013-04-26 00:00:00

abstract：BACKGROUND:Skin toxicity is a common side effect of radiotherapy for solid tumors. Its management can cause treatment gaps and thus can impair cancer treatment. At present, in many countries no standard recommendation for treatment of skin during radiotherapy exists. In this study, we explored the effect of topically-a...

journal_title：BMC medicine

authors： Pajonk F,Riedisser A,Henke M,McBride WH,Fiebich B

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Dystroglycanopathies are a group of inherited disorders characterized by vast clinical and genetic heterogeneity and caused by abnormal functioning of the ECM receptor dystroglycan (Dg). Remarkably, among many cases of diagnosed dystroglycanopathies, only a small fraction can be linked directly to mutations ...

journal_title：BMC medicine

authors： Yatsenko AS,Kucherenko MM,Xie Y,Aweida D,Urlaub H,Scheibe RJ,Cohen S,Shcherbata HR

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:Tobacco smoking is a leading cause of cardiovascular disease (CVD) morbidity and mortality. Evidence on the relation of smoking to different subtypes of CVD, across fatal and non-fatal outcomes, is limited. METHODS:A prospective study of 188,167 CVD- and cancer-free individuals aged ≥ 45 years from the Aust...

journal_title：BMC medicine

authors： Banks E,Joshy G,Korda RJ,Stavreski B,Soga K,Egger S,Day C,Clarke NE,Lewington S,Lopez AD

更新日期：2019-07-03 00:00:00

abstract：BACKGROUND:The treatment of patients with haematological malignancies by means of haematopoietic stem cell transplantation (HSCT) is often accompanied by life threatening infections. With emerging antimicrobial resistance there is an increased need for new agents, with a beneficial safety profile. Therefore we evaluate...

journal_title：BMC medicine

authors： Velden WJ,van Iersel TM,Blijlevens NM,Donnelly JP

更新日期：2009-09-08 00:00:00

abstract：BACKGROUND:Armed conflicts are associated with a wide range of impacts on the mental health of children and adolescents. We evaluated the effectiveness of a school-based intervention aimed at reducing symptoms of posttraumatic stress disorder, depression, and anxiety (treatment aim); and improving a sense of hope and f...

journal_title：BMC medicine

authors： Tol WA,Komproe IH,Jordans MJ,Ndayisaba A,Ntamutumba P,Sipsma H,Smallegange ES,Macy RD,de Jong JT

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Major depression, although frequent in primary care, is commonly hidden behind multiple physical complaints that are often the first and only reason for patient consultation. Major depression can be screened by two validated questions that are easier to use in primary care than the full Diagnostic and Statis...

journal_title：BMC medicine

authors： Lombardo P,Vaucher P,Haftgoli N,Burnand B,Favrat B,Verdon F,Bischoff T,Herzig L

更新日期：2011-10-18 00:00:00

abstract：:Nanooncology, the application of nanobiotechnology to the management of cancer, is currently the most important chapter of nanomedicine. Nanobiotechnology has refined and extended the limits of molecular diagnosis of cancer, for example, through the use of gold nanoparticles and quantum dots. Nanobiotechnology has als...

journal_title：BMC medicine

authors： Jain KK

更新日期：2010-12-13 00:00:00

abstract：BACKGROUND:Alcohol consumption is a leading contributor to death and disability worldwide, but previous research has not examined the effects of different patterns of alcohol consumption. The study objective was to understand the relationship between different alcohol consumption patterns and adverse health outcomes ri...

journal_title：BMC medicine

authors： Jani BD,McQueenie R,Nicholl BI,Field R,Hanlon P,Gallacher KI,Mair FS,Lewsey J

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:Breast cancer patients who have not previously attended mammography screening may be more likely to discontinue adjuvant hormone therapy and therefore have a worse disease prognosis. METHODS:We conducted a population-based cohort study using data from Stockholm Mammography Screening Program, Stockholm-Gotla...

journal_title：BMC medicine

authors： He W,Eriksson L,Törnberg S,Strand F,Hall P,Czene K

更新日期：2019-01-31 00:00:00

abstract：:The lack of formal training programs for peer reviewers places the scientific quality of biomedical publications at risk, as the introduction of 'hidden' bias may not be easily recognized by the reader. The exponential increase in the number of manuscripts submitted for publication worldwide, estimated in the millions...

journal_title：BMC medicine

authors： Stahel PF,Moore EE

更新日期：2014-09-26 00:00:00

abstract：:This is an Erratum to BMC Medicine 2015, 13:59, highlighting previously undeclared competing interests and including more information in the acknowledgements section.Please see related article: http://www.biomedcentral.com/1741-7015/13/59. The statement in the competing interests should read as follows: This study is ...

journal_title：BMC medicine

authors： Huang T,Xu M,Lee A,Cho S,Qi L

更新日期：2015-04-16 00:00:00

abstract：BACKGROUND:The use of early morning sputum samples (EMS) to diagnose tuberculosis (TB) can result in treatment delay given the need for the patient to return to the clinic with the EMS, increasing the chance of patients being lost during their diagnostic workup. However, there is little evidence to support the superior...

journal_title：BMC medicine

authors： Murphy ME,Phillips PPJ,Mendel CM,Bongard E,Bateson ALC,Hunt R,Murthy S,Singh KP,Brown M,Crook AM,Nunn AJ,Meredith SK,Lipman M,McHugh TD,Gillespie SH,REMoxTB Consortium.

更新日期：2017-10-27 00:00:00