Ethanol Mediated Inhibition of Synaptic Vesicle Recycling at Amygdala Glutamate Synapses Is Dependent upon Munc13-2.

abstract：:Regaining communication abilities in patients who are unable to speak or move is one of the main goals in decoding brain waves for brain-computer interface (BCI) control. Many BCI approaches designed for communication rely on attention to visual stimuli, commonly applying an oddball paradigm, and require both eye move...

journal_title：Frontiers in neuroscience

authors： Reichert C,Tellez Ceja IF,Sweeney-Reed CM,Heinze HJ,Hinrichs H,Dürschmid S

更新日期：2020-12-01 00:00:00

abstract：:Neuromorphic Vision sensors have improved greatly since the first silicon retina was presented almost three decades ago. They have recently matured to the point where they are commercially available and can be operated by laymen. However, despite improved availability of sensors, there remains a lack of good datasets,...

journal_title：Frontiers in neuroscience

authors： Tan C,Lallee S,Orchard G

更新日期：2015-10-13 00:00:00

abstract：:The sliding-window-based dynamic functional connectivity networks (D-FCNs) derived from resting-state functional magnetic resonance imaging (rs-fMRI) are effective methods for diagnosing various neurological diseases, including autism spectrum disorder (ASD). However, traditional D-FCNs are low-order networks based on...

journal_title：Frontiers in neuroscience

authors： Zhao F,Chen Z,Rekik I,Lee SW,Shen D

更新日期：2020-04-28 00:00:00

abstract：Background:Cranial irradiation is a common therapy for the treatment of brain tumors, but unfortunately patients suffer from side effects, particularly cognitive impairment, caused by neurodegenerative and neuroinflammatory mechanisms. Finding a therapeutic agent protecting hippocampal neurons would be beneficial. Fing...

journal_title：Frontiers in neuroscience

authors： Metzdorf J,Hobloss Z,Schlevogt S,Ayzenberg I,Stahlke S,Pedreiturria X,Haupeltshofer S,Gold R,Tönges L,Kleiter I

更新日期：2019-07-09 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) allows studying human brain function non-invasively up to the spatial resolution of cortical columns and layers. Most fMRI acquisitions rely on the blood oxygenation level dependent (BOLD) contrast employing T(*) 2 weighted 2D multi-slice echo-planar imaging (EPI). At ultra...

journal_title：Frontiers in neuroscience

authors： Kemper VG,De Martino F,Vu AT,Poser BA,Feinberg DA,Goebel R,Yacoub E

更新日期：2015-05-05 00:00:00

abstract：:Bispectral analysis is a signal processing technique that makes it possible to capture the non-linear and non-Gaussian properties of the EEG signals. It has found various applications in EEG research and clinical practice, including the assessment of anesthetic depth, the identification of epileptic seizures, and more...

journal_title：Frontiers in neuroscience

authors： Chella F,D'Andrea A,Basti A,Pizzella V,Marzetti L

更新日期：2017-05-16 00:00:00

abstract：:Risperidone (RIS), an atypical antipsychotic has been found to show anti-inflammatory effect against lipopolysaccharide (LPS)-induced inflammation. In vitro study has revealed that RIS inhibits the LPS-induced reactive oxygen species (ROS) formation. We investigated the antioxidant effects of RIS on LPS-induced oxidat...

journal_title：Frontiers in neuroscience

authors： Al-Amin MM,Choudhury MFR,Chowdhury AS,Chowdhury TR,Jain P,Kazi M,Alkholief M,Alshehri SM,Reza HM

更新日期：2018-06-08 00:00:00

abstract：:Stimulation of the pineal gland via its sympathetic innervation pathway results in the production of N-acetylserotonin and melatonin. Melatonin has many therapeutic roles and is heavily implicated in the regulation of the sleep-wake cycle. In addition, N-acetylserotonin has recently been reported to promote neurogenes...

journal_title：Frontiers in neuroscience

authors： Lumsden SC,Clarkson AN,Cakmak YO

更新日期：2020-04-02 00:00:00

abstract：:How speech signals are analyzed and represented remains a foundational challenge both for cognitive science and neuroscience. A growing body of research, employing various behavioral and neurobiological experimental techniques, now points to the perceptual relevance of both phoneme-sized (10-40 Hz modulation frequency...

journal_title：Frontiers in neuroscience

authors： Chait M,Greenberg S,Arai T,Simon JZ,Poeppel D

更新日期：2015-06-16 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) is increasingly used in both research and therapeutic settings, but its precise mechanisms remain largely unknown. At a neuronal level, tDCS modulates cortical excitability by shifting the resting membrane potential in a polarity-dependent way: anodal stimulation increase...

journal_title：Frontiers in neuroscience

authors： Varoli E,Pisoni A,Mattavelli GC,Vergallito A,Gallucci A,Mauro LD,Rosanova M,Bolognini N,Vallar G,Romero Lauro LJ

更新日期：2018-05-15 00:00:00

abstract：:Background: Gambling disorder (GD) is the most common behavioral addiction and shares pathophysiological and clinical features with substance use disorders (SUDs). Effective therapeutic interventions for GD are lacking. Non-invasive brain stimulation (NIBS) may represent a promising treatment option for GD. Objective:...

journal_title：Frontiers in neuroscience

authors： Zucchella C,Mantovani E,Federico A,Lugoboni F,Tamburin S

更新日期：2020-08-18 00:00:00

abstract：:Early detection is critical for effective management of Alzheimer's disease (AD) and screening for mild cognitive impairment (MCI) is common practice. Among several deep-learning techniques that have been applied to assessing structural brain changes on magnetic resonance imaging (MRI), convolutional neural network (C...

journal_title：Frontiers in neuroscience

authors： Pan D,Zeng A,Jia L,Huang Y,Frizzell T,Song X

更新日期：2020-05-13 00:00:00

abstract：:Electroencephalography (EEG) is perhaps the most widely used brain-imaging technique for pediatric populations. However, EEG signals are prone to distortion by motion. Compared to adults, infants' motion is both more frequent and less stereotypical yet motion effects on the infant EEG signal are largely undocumented. ...

journal_title：Frontiers in neuroscience

authors： Georgieva S,Lester S,Noreika V,Yilmaz MN,Wass S,Leong V

更新日期：2020-04-28 00:00:00

abstract：:Using BOLD functional magnetic resonance imaging (fMRI) techniques, we examined the relationships between activities in the neural systems elicited by the decision stage of the Iowa Gambling Task (IGT), and food choices of either vegetables or snacks high in fat and sugar. Twenty-three healthy normal weight adolescent...

journal_title：Frontiers in neuroscience

authors： He Q,Xiao L,Xue G,Wong S,Ames SL,Xie B,Bechara A

更新日期：2014-11-04 00:00:00

abstract：:While convolutional neural networks (CNNs) continue to renew state-of-the-art performance across many fields of machine learning, their hardware implementations tend to be very costly and inflexible. Neuromorphic hardware, on the other hand, targets higher efficiency but their inference accuracy lags far behind that o...

journal_title：Frontiers in neuroscience

authors： Sim H,Lee J

更新日期：2020-12-23 00:00:00

abstract：:In patients with impaired liver function and hepatic encephalopathy (HE), consistent elevations of blood ammonia concentration suggest a crucial role in the pathogenesis of HE. Ammonia and acetate are metabolized in brain both primarily in astrocytes. Here, we used dynamic [(11)C]acetate PET of the brain to measure th...

journal_title：Frontiers in neuroscience

authors： Iversen P,Mouridsen K,Hansen MB,Jensen SB,Sørensen M,Bak LK,Waagepetersen HS,Schousboe A,Ott P,Vilstrup H,Keiding S,Gjedde A

更新日期：2014-11-03 00:00:00

abstract：:Orexins are hypothalamic neuropeptides that were initially identified in the rat brain as endogenous ligands for an (previously) orphan G-protein-coupled receptor (GPCR). They are multitasking peptides involved in many physiological functions, including regulation of feeding behavior, wakefulness and autonomic/neuroen...

journal_title：Frontiers in neuroscience

authors： Soya S,Sakurai T

更新日期：2020-07-10 00:00:00

abstract：:The increasing rate of age-related hearing loss (ARHL), with its subsequent reduction in quality of life and increase in health care costs, requires new therapeutic strategies to reduce and delay its impact. The goal of this study was to determine if ARHL could be reduced in a rat model by administering a combination ...

journal_title：Frontiers in neuroscience

authors： Alvarado JC,Fuentes-Santamaría V,Gabaldón-Ull MC,Juiz JM

更新日期：2018-07-31 00:00:00

abstract：:The efficacy of neuronal function requires a well-balanced extracellular ion homeostasis and a steady supply with nutrients and metabolites. Therefore, all organisms equipped with a complex nervous system developed a so-called blood-brain barrier, protecting it from an uncontrolled entry of solutes, metabolites or pat...

journal_title：Frontiers in neuroscience

authors： Limmer S,Weiler A,Volkenhoff A,Babatz F,Klämbt C

更新日期：2014-11-14 00:00:00

abstract：:Openness to experience (OTE) has relatively stable and heritable characteristics. Previous studies have used candidate gene approaches to explore the genetic mechanisms of OTE, but genome-wide polygenic scores have a greater genetic effect than other genetic analysis methods, and previous studies have never examined t...

journal_title：Frontiers in neuroscience

authors： Ren Z,Liu C,Meng J,Liu Q,Shi L,Wu X,Song L,Qiu J

更新日期：2021-01-11 00:00:00

abstract：UNLABELLED:α2-adrenoceptors (α2AR) lower central sympathetic output and peripheral catecholamine release, and may therefore prevent sympathetic hyperactivity and hypertension. The α2AR are dysfunctional in male spontaneously hypertensive rats (SHR). Premenopausal females are less hypertensive than males. The purpose of...

journal_title：Frontiers in neuroscience

authors： Berg T

更新日期：2016-03-30 00:00:00

abstract：:Numerous observational studies have shown that depressive symptoms are common in individuals with mild cognitive impairment (MCI) who have a higher rate of progress to dementia. However, it is still uncertain whether there are any differences between MCI patients with and without depression symptom in their brain func...

journal_title：Frontiers in neuroscience

authors： Yu Y,Li Z,Lin Y,Yu J,Peng G,Zhang K,Jia X,Luo B

更新日期：2019-12-17 00:00:00

abstract：:Event-related potentials (ERPs) are often used in brain-computer interfaces (BCIs) for communication or system control for enhancing or regaining control for motor-disabled persons. Especially results from single-trial EEG classification approaches for BCIs support correlations between single-trial ERP detection perfo...

journal_title：Frontiers in neuroscience

authors： Kirchner EA,Kim SK

更新日期：2018-03-27 00:00:00

abstract：:Abnormal accumulation of TAR DNA-binding protein 43 (TDP-43) in the cytoplasm and its disappearance from the nucleus are pathological features of amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) and are directly involved in the pathogenesis of these conditions. TDP-43 is an essential nuclear protein...

journal_title：Frontiers in neuroscience

authors： Sugai A,Kato T,Koyama A,Koike Y,Kasahara S,Konno T,Ishihara T,Onodera O

更新日期：2018-02-01 00:00:00

abstract：:The prevalence of depressive disorders is growing worldwide, notably due to stagnation in the development of drugs with greater antidepressant efficacy, the continuous large proportion of patients who do not respond to conventional antidepressants, and the increasing rate of chronic medical conditions associated with ...

journal_title：Frontiers in neuroscience

authors： Vancassel S,Capuron L,Castanon N

更新日期：2018-07-24 00:00:00

abstract：:The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal cord, providing sensory input to the micturition centers within the central nervous system. Under normal conditions, the continuous activation of these neurons during bladder distension goes mostly unnoticed. However, for ...

journal_title：Frontiers in neuroscience

authors： Grundy L,Caldwell A,Brierley SM

更新日期：2018-12-12 00:00:00

abstract：:Gambling is a widespread recreational activity and requires pitting the values of potential wins and losses against their probability of occurrence. Neuropsychological research showed that betting behavior on laboratory gambling tasks is highly sensitive to focal lesions to the ventromedial prefrontal cortex (vmPFC) a...

journal_title：Frontiers in neuroscience

authors： Studer B,Apergis-Schoute AM,Robbins TW,Clark L

更新日期：2012-04-18 00:00:00

abstract：:Analog arrays are a promising emerging hardware technology with the potential to drastically speed up deep learning. Their main advantage is that they employ analog circuitry to compute matrix-vector products in constant time, irrespective of the size of the matrix. However, ConvNets map very unfavorably onto analog a...

journal_title：Frontiers in neuroscience

authors： Rasch MJ,Gokmen T,Rigotti M,Haensch W

更新日期：2019-07-30 00:00:00

abstract：:The detection of mild cognitive impairment (MCI), the transitional stage between normal cognitive changes of aging and the cognitive decline caused by AD, is of paramount clinical importance, since MCI patients are at increased risk of progressing into AD. Electroencephalographic (EEG) alterations in the spectral cont...

journal_title：Frontiers in neuroscience

authors： Dimitriadis SI,Laskaris NA,Bitzidou MP,Tarnanas I,Tsolaki MN

更新日期：2015-10-20 00:00:00

abstract：:We investigated whether the categorical perception (CP) of speech might also provide a mechanism that aids its perception in noise. We varied signal-to-noise ratio (SNR) [clear, 0 dB, -5 dB] while listeners classified an acoustic-phonetic continuum (/u/ to /a/). Noise-related changes in behavioral categorization were ...

journal_title：Frontiers in neuroscience

authors： Bidelman GM,Bush LC,Boudreaux AM

更新日期：2020-02-27 00:00:00