Alteration in Taste Perception in Cancer: Causes and Strategies of Treatment.

Abstract:

:The sense of taste is responsible for the detection and ingestion of food to cover energetic requirements in health and disease. The change in taste perception might lead to malnutrition that is usually one of the frequent causes of morbidity and mortality in patients with cancer. In this review, we summarize the mechanisms of taste perception and how they are altered in cancer. We also address the question of the implication of inflammation, responsible for the alterations in taste modalities. We highlight the role of radio- and chemotherapy in the modulation of taste physiology. Other several factors like damage to taste progenitor cells and disruption of gut microbiota are also dealt with relation to taste perception in cancer. We further shed light on how to restore taste acuity, by using different preventive methods, dietary modifications and pharmacotherapy in subjects with advanced cancer state.

journal_name

Front Physiol

journal_title

Frontiers in physiology

authors

Murtaza B,Hichami A,Khan AS,Ghiringhelli F,Khan NA

doi

10.3389/fphys.2017.00134

subject

Has Abstract

pub_date

2017-03-08 00:00:00

pages

134

issn

1664-042X

journal_volume

8

pub_type

杂志文章,评审
  • A Personalized Signature and Chronotherapy-Based Platform for Improving the Efficacy of Sepsis Treatment.

    abstract::Sepsis remains a major therapeutic challenge and is associated with a high rate of morbidity and mortality. It is a dynamic condition in which multiple parameters change over time, rendering it difficult to overcome the various injurious responses, which worsen the prognosis in these patients. The prognosis of sepsis ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2019.01542

    authors: Kenig A,Ilan Y

    更新日期:2019-12-19 00:00:00

  • Role of nitric oxide and related molecules in schizophrenia pathogenesis: biochemical, genetic and clinical aspects.

    abstract::Currently, schizophrenia is considered a multifactorial disease. Over the past 50 years, many investigators have considered the role of toxic free radicals in the etiology of schizophrenia. This is an area of active research which is still evolving. Here, we review the recent data and current concepts on the roles of ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2015.00139

    authors: Nasyrova RF,Ivashchenko DV,Ivanov MV,Neznanov NG

    更新日期:2015-05-11 00:00:00

  • Validity and Reliability of the 30-s Continuous Jump for Anaerobic Power and Capacity Assessment in Combat Sport.

    abstract::Cycling test such Wingate anaerobic test (WAnT) is used to measure anaerobic power (AP), but not anaerobic capacity (AC, i.e., the metabolic energy demand). However, in sports that do not involve cycling movements (Karate), the continuous jump for 30 s (vertical jumps for 30 s) has been extensively used to measure ana...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2018.00543

    authors: Čular D,Ivančev V,Zagatto AM,Milić M,Beslija T,Sellami M,Padulo J

    更新日期:2018-05-15 00:00:00

  • Partial Amino Acid Metabolism and Glutamine Synthesis as the Ammonia Defensive Strategies During Aerial Exposure in Chinese Loach Paramisgurnus dabryanus.

    abstract::The Paramisgurnus dabryanus was exposed to air to assess the changes in plasma, liver and muscle free amino acid (FAA) contents. The FAA concentrations in plasma, liver and muscle of P. dabryanus were significantly affected by aerial exposure (P < 0.05). After 12 h of aerial exposure, the plasma glutamate contents inc...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.00014

    authors: Zhang YL,Wang GY,Zhang ZH,Xie YY,Jin H,Dong ZR

    更新日期:2019-01-29 00:00:00

  • Function and Regulation of Lipid Biology in Caenorhabditis elegans Aging.

    abstract::Rapidly expanding aging populations and a concomitant increase in the prevalence of age-related diseases are global health problems today. Over the past three decades, a large body of work has led to the identification of genes and regulatory networks that affect longevity and health span, often benefiting from the tr...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2012.00143

    authors: Hou NS,Taubert S

    更新日期:2012-05-18 00:00:00

  • The Whitish Inner Mantle of the Giant Clam, Tridacna squamosa, Expresses an Apical Plasma Membrane Ca2+-ATPase (PMCA) Which Displays Light-Dependent Gene and Protein Expressions.

    abstract::Giant clams live in symbiosis with extracellular zooxanthellae and display high rates of growth and shell formation (calcification) in light. Light-enhanced calcification requires an increase in the supply of Ca2+ to, and simultaneously an augmented removal of H+ from, the extrapallial fluid where shell formation occu...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2017.00781

    authors: Ip YK,Hiong KC,Goh EJK,Boo MV,Choo CYL,Ching B,Wong WP,Chew SF

    更新日期:2017-10-10 00:00:00

  • Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease.

    abstract::In aged subjects, late-onset Alzheimer's disease (LOAD) starts in the lateral entorhinal allocortex where a failure of clearance mechanisms triggers an accumulation of neurotoxic amyloid-β42 oligomers (Aβ42-os). In neurons and astrocytes, Aβ42-os enhance the transcription of Aβ precursor protein (APP) and β-secretase/...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2016.00134

    authors: Chiarini A,Armato U,Liu D,Dal Prà I

    更新日期:2016-04-26 00:00:00

  • The Effect of Heart Rate on Jump-Shot Accuracy of Adolescent Basketball Players.

    abstract::Basketball is a team sport, where fundamental skills - fundamentals - are key determinants for success. Jump-shot (JS) is a basketball fundamental used frequently during game. It is interesting to spread light on the relationship between effort intensity and JS ability. Study aim was to investigate different heart rat...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2018.01065

    authors: Padulo J,Nikolaidis PT,Cular D,Dello Iacono A,Vando S,Galasso M,Lo Storto D,Ardigò LP

    更新日期:2018-08-03 00:00:00

  • Intravenous Vitamin C for Cancer Therapy - Identifying the Current Gaps in Our Knowledge.

    abstract::The use of intravenous vitamin C (IVC) for cancer therapy has long been an area of intense controversy. Despite this, high dose IVC has been administered for decades by complementary health care practitioners and physicians, with little evidence base resulting in inconsistent clinical practice. In this review we pose ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2018.01182

    authors: Carr AC,Cook J

    更新日期:2018-08-23 00:00:00

  • Plasma Protein and MicroRNA Biomarkers of Insulin Resistance: A Network-Based Integrative -Omics Analysis.

    abstract::Although insulin resistance (IR) is a key pathophysiologic condition underlying various metabolic disorders, impaired cellular glucose uptake is one of many manifestations of metabolic derangements in the human body. To study the systems-wide molecular changes associated with obesity-dependent IR, we integrated inform...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.00379

    authors: Choi H,Koh HWL,Zhou L,Cheng H,Loh TP,Parvaresh Rizi E,Toh SA,Ronnett GV,Huang BE,Khoo CM

    更新日期:2019-04-05 00:00:00

  • The Effect of Chinese Herbal Medicine on Quality of Life and Exercise Tolerance in Heart Failure With Preserved Ejection Fraction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    abstract::Background: Chinese herbal medicine (CHM) has a good effect of alleviating symptoms and improving quality of life and exercise tolerance in patients with heart failure with preserved ejection fraction (HFpEF), but it wasn't sufficiently valued and promoted because of the lack of evidence-based medical evidence. Aim: T...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2018.01420

    authors: Wang J,Yang R,Zhang F,Jia C,Wang P,Liu J,Gao K,Xie H,Wang J,Zhao H,Chen J,Wang W

    更新日期:2018-10-26 00:00:00

  • Posttranslational Amelogenin Processing and Changes in Matrix Assembly during Enamel Development.

    abstract::The extracellular tooth enamel matrix is a unique, protein-rich environment that provides the structural basis for the growth of long and parallel oriented enamel crystals. Here we have conducted a series of in vivo and in vitro studies to characterize the changes in matrix shape and organization that take place durin...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2017.00790

    authors: Pandya M,Lin T,Li L,Allen MJ,Jin T,Luan X,Diekwisch TGH

    更新日期:2017-10-17 00:00:00

  • Integrative Computational Network Analysis Reveals Site-Specific Mediators of Inflammation in Alzheimer's Disease.

    abstract::Alzheimer's disease (AD) is a major neurodegenerative disease and is one of the most common cause of dementia in older adults. Among several factors, neuroinflammation is known to play a critical role in the pathogenesis of chronic neurodegenerative diseases. In particular, studies of brains affected by AD show a clea...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2018.00154

    authors: Ravichandran S,Michelucci A,Del Sol A

    更新日期:2018-03-02 00:00:00

  • Corrigendum: Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3).

    abstract::[This corrects the article DOI: 10.3389/fphys.2019.01574.]. ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,已发布勘误

    doi:10.3389/fphys.2020.00072

    authors: Figueroa VA,Jara O,Oliva CA,Ezquer M,Ezquer F,Retamal MA,Martínez AD,Altenberg GA,Vargas AA

    更新日期:2020-02-11 00:00:00

  • The Circadian Clock Improves Fitness in the Fruit Fly, Drosophila melanogaster.

    abstract::It is assumed that a properly timed circadian clock enhances fitness, but only few studies have truly demonstrated this in animals. We raised each of the three classical Drosophila period mutants for >50 generations in the laboratory in competition with wildtype flies. The populations were either kept under a conventi...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.01374

    authors: Horn M,Mitesser O,Hovestadt T,Yoshii T,Rieger D,Helfrich-Förster C

    更新日期:2019-11-01 00:00:00

  • Longitudinal Study of Functional Reinnervation of the Denervated Skin by Collateral Sprouting of Peptidergic Nociceptive Nerves Utilizing Laser Doppler Imaging.

    abstract::Restitution of cutaneous sensory function is accomplished by neural regenerative processes of distinct mechanisms following peripheral nerve lesions. Although methods available for the study of functional cutaneous nerve regeneration are specific and accurate, they are unsuitable for the longitudinal follow-up of the ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2020.00439

    authors: Lakatos S,Jancsó G,Horváth Á,Dobos I,Sántha P

    更新日期:2020-05-21 00:00:00

  • Microbial pathways in colonic sulfur metabolism and links with health and disease.

    abstract::Sulfur is both crucial to life and a potential threat to health. While colonic sulfur metabolism mediated by eukaryotic cells is relatively well studied, much less is known about sulfur metabolism within gastrointestinal microbes. Sulfated compounds in the colon are either of inorganic (e.g., sulfates, sulfites) or or...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2012.00448

    authors: Carbonero F,Benefiel AC,Alizadeh-Ghamsari AH,Gaskins HR

    更新日期:2012-11-28 00:00:00

  • Muscular Adaptations to Whole Body Blood Flow Restriction Training and Detraining.

    abstract::Resistance training with blood flow restriction is typically performed during single exercises for the lower- or upper-body, which may not replicate real world programming. The present study examined the change in muscle strength and mass in a young healthy population during an 8-week whole body resistance training pr...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.01099

    authors: Brandner CR,Clarkson MJ,Kidgell DJ,Warmington SA

    更新日期:2019-09-10 00:00:00

  • Embryonic Exposure to Valproic Acid Affects Social Predispositions for Dynamic Cues of Animate Motion in Newly-Hatched Chicks.

    abstract::Early predispositions to preferentially orient toward cues associated with social partners have been documented in several vertebrate species including human neonates and domestic chicks. Human newborns at high familiar risk of Autism Spectrum Disorder (ASD) show differences in their attention toward these predisposed...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.00501

    authors: Lorenzi E,Pross A,Rosa-Salva O,Versace E,Sgadò P,Vallortigara G

    更新日期:2019-04-30 00:00:00

  • Qualitative modeling identifies IL-11 as a novel regulator in maintaining self-renewal in human pluripotent stem cells.

    abstract::Pluripotency in human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) is regulated by three transcription factors-OCT3/4, SOX2, and NANOG. To fully exploit the therapeutic potential of these cells it is essential to have a good mechanistic understanding of the maintenance of self-renewal and pl...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2013.00303

    authors: Peterson H,Abu Dawud R,Garg A,Wang Y,Vilo J,Xenarios I,Adjaye J

    更新日期:2013-10-28 00:00:00

  • Effect of phenylephrine vs. ephedrine on frontal lobe oxygenation during caesarean section with spinal anesthesia: an open label randomized controlled trial.

    abstract:BACKGROUND:During caesarean section spinal anesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine. Phenylephrine is however reported to reduce the near infrared spectroscopy-determined frontal lobe oxygenation (ScO2) but whether that is the case for patients expo...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2014.00081

    authors: Foss VT,Christensen R,Rokamp KZ,Nissen P,Secher NH,Nielsen HB

    更新日期:2014-03-03 00:00:00

  • Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of Spontaneous SR Ca 2+ Release.

    abstract::Early afterdepolarization (EAD) is known to cause lethal ventricular arrhythmias in long QT syndrome (LQTS). In this study, dynamical mechanisms of EAD formation in human ventricular myocytes (HVMs) were investigated using the mathematical model developed by ten Tusscher and Panfilov (Am J Physiol Heart Circ Physiol 2...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.01545

    authors: Kurata Y,Tsumoto K,Hayashi K,Hisatome I,Kuda Y,Tanida M

    更新日期:2020-01-10 00:00:00

  • Antineoplastic Drug-Induced Cardiotoxicity: A Redox Perspective.

    abstract::Antineoplastic drugs can be associated with several side effects, including cardiovascular toxicity (CTX). Biochemical studies have identified multiple mechanisms of CTX. Chemoterapeutic agents can alter redox homeostasis by increasing the production of reactive oxygen species (ROS) and reactive nitrogen species RNS. ...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2018.00167

    authors: Varricchi G,Ameri P,Cadeddu C,Ghigo A,Madonna R,Marone G,Mercurio V,Monte I,Novo G,Parrella P,Pirozzi F,Pecoraro A,Spallarossa P,Zito C,Mercuro G,Pagliaro P,Tocchetti CG

    更新日期:2018-03-07 00:00:00

  • Differential transport function of lymphatic vessels in the rat tail model and the long-term effects of Indocyanine Green as assessed with near-infrared imaging.

    abstract:INTRODUCTION:Near-infrared (NIR) imaging has emerged as a novel imaging modality for assessing lymphatic function in vivo. While the technique has provided quantitative data previously unavailable, questions remain in regards to the spatiotemporal capabilities of the approach. We address three of the more important iss...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2013.00215

    authors: Weiler M,Dixon JB

    更新日期:2013-08-15 00:00:00

  • EPCR Gene Ser219Gly Polymorphism and Venous Thromboembolism: A Meta-Analysis of 9,494 Subjects.

    abstract::Background: Although endothelial cell protein C receptor (EPCR) gene Ser219Gly polymorphism has been associated with venous thromboembolism (VTE) susceptibility, no clear consensus has yet been reached. Objective and methods: A meta-analysis of 9,494 subjects from 13 individual studies was conducted to better elucidat...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2017.00339

    authors: Li YY,Wu JJ,Yang XX,Geng HY,Gong G,Kim HJ

    更新日期:2017-05-26 00:00:00

  • Respiratory Metabolism Responses of Chinese Mitten Crab, Eriocheir sinensis and Chinese Grass Shrimp, Palaemonetes sinensis, Subjected to Environmental Hypoxia Stress.

    abstract::Environmental hypoxia represents a major physiological challenge for Eriocheir sinensis and Palaemonetes sinensis and is a severe problem in aquaculture. Therefore, understanding the metabolic response mechanisms of E. sinensis and P. sinensis, which are economically important species, to environmental hypoxia and reo...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2018.01559

    authors: Bao J,Li X,Yu H,Jiang H

    更新日期:2018-11-06 00:00:00

  • Photodynamic Physiology-Photonanomanipulations in Cellular Physiology with Protein Photosensitizers.

    abstract::Singlet oxygen generated in a type II photodynamic action, due to its limited lifetime (1 μs) and reactive distance (<10 nm), could regulate live cell function nanoscopically. The genetically-encoded protein photosensitizers (engineered fluorescent proteins such as KillerRed, TagRFP, and flavin-binding proteins such a...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2017.00191

    authors: Jiang HN,Li Y,Cui ZJ

    更新日期:2017-04-04 00:00:00

  • Increases in apoptosis, caspase activity and expression of p53 and bax, and the transition between two types of mitochondrion-rich cells, in the gills of the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater.

    abstract::This study aimed to test the hypothesis that branchial osmoregulatory acclimation involved increased apoptosis and replacement of mitochdonrion-rich cells (MRCs) in the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater. A significant increase in branchial caspase-3/-7 act...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2013.00135

    authors: Ching B,Chen XL,Yong JH,Wilson JM,Hiong KC,Sim EW,Wong WP,Lam SH,Chew SF,Ip YK

    更新日期:2013-06-07 00:00:00

  • Match Fatigue Time-Course Assessment Over Four Days: Usefulness of the Hooper Index and Heart Rate Variability in Professional Soccer Players.

    abstract::The aims of the present study were to (a) examine recovery time-course and (b) analyze the usefulness of the Hooper-Index (wellness index) and resting heart rate variability (HRV) in professional soccer players during an in-season phase. The Hooper-Index and resting HRV were collected on matchday and on the four follo...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章

    doi:10.3389/fphys.2019.00109

    authors: Rabbani A,Clemente FM,Kargarfard M,Chamari K

    更新日期:2019-02-19 00:00:00

  • Imaging Atherosclerosis by PET, With Emphasis on the Role of FDG and NaF as Potential Biomarkers for This Disorder.

    abstract::Molecular imaging has emerged in the past few decades as a novel means to investigate atherosclerosis. From a pathophysiological perspective, atherosclerosis is characterized by microscopic inflammation and microcalcification that precede the characteristic plaque buildup in arterial walls detected by traditional asse...

    journal_title:Frontiers in physiology

    pub_type: 杂志文章,评审

    doi:10.3389/fphys.2020.511391

    authors: Mayer M,Borja AJ,Hancin EC,Auslander T,Revheim ME,Moghbel MC,Werner TJ,Alavi A,Rajapakse CS

    更新日期:2020-10-22 00:00:00