Development of Chitosan/Poly(Vinyl Alcohol) Electrospun Nanofibers for Infection Related Wound Healing.

Abstract:

:Chitosan is a cheap resource, which is widely used in biomedical applications due to its biocompatible and antibacterial properties. In this study, composite nanofibrous membranes of chitosan (CS) and poly(vinyl alcohol) (PVA) loaded with antibiotics at different ratios were successfully fabricated by electrospinning. The composite nanofibers were subjected to further analysis by scanning electron microscopy (SEM). SEM images revealed that the volumetric ratio of CS/PVA at 50/50 achieved an optimal nanofibrous structure (i.e., that most similar to natural tissues) compared with other volumetric ratios, which indicated that this CS/PVA electrospun scaffold has great potential to be used for infection related wound dressing for skin tissue regeneration.

journal_name

Front Physiol

journal_title

Frontiers in physiology

authors

Wang M,Roy AK,Webster TJ

doi

10.3389/fphys.2016.00683

subject

Has Abstract

pub_date

2017-01-11 00:00:00

pages

683

issn

1664-042X

journal_volume

7

pub_type

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